-
1
-
-
0028345075
-
The clinical potential of renin inhibitors and angiotensin antagonists
-
Apr
-
Cody RJ. The clinical potential of renin inhibitors and angiotensin antagonists. Drugs 1994 Apr; 47: 586-98
-
(1994)
Drugs
, vol.47
, pp. 586-598
-
-
Cody, R.J.1
-
2
-
-
0030032937
-
Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure
-
Jan
-
Awan NA, Mason DT. Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure. Am Heart J 1996 Jan; 131: 177-85
-
(1996)
Am Heart J
, vol.131
, pp. 177-185
-
-
Awan, N.A.1
Mason, D.T.2
-
3
-
-
0029773902
-
Biology of angiotensin II receptor inhibition with a focus on losartan; a new drug for the treatment of hypertension
-
Sep
-
Tallant EA, Ferrario CM. Biology of angiotensin II receptor inhibition with a focus on losartan; a new drug for the treatment of hypertension. Expert Opin Invest Drug 1996 Sep: 5: 1201-14
-
(1996)
Expert Opin Invest Drug
, vol.5
, pp. 1201-1214
-
-
Tallant, E.A.1
Ferrario, C.M.2
-
4
-
-
0029017714
-
The angiotensin II type I receptor antagonists: A new class of antihypertensive drugs
-
Jul 10
-
Bauer JH, Reams GP. The angiotensin II type I receptor antagonists: a new class of antihypertensive drugs. Arch Intern Med 1995 Jul 10; 155: 1361-8
-
(1995)
Arch Intern Med
, vol.155
, pp. 1361-1368
-
-
Bauer, J.H.1
Reams, G.P.2
-
5
-
-
0027208070
-
Angiotensin II receptors and angiotensin II receptor antagonists
-
Timmermans PBMWM. Wong PC, Chiu AT, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993; 45 (2): 205-51
-
(1993)
Pharmacol Rev
, vol.45
, Issue.2
, pp. 205-251
-
-
Timmermans, P.B.M.W.M.1
Wong, P.C.2
Chiu, A.T.3
-
7
-
-
0029549912
-
Valsartan: Preclinical and clinical profile of an antihypertensive angiotensin-II antagonist
-
Criseione L. Bradley WA. Bühlmayer P, et al. Valsartan: preclinical and clinical profile of an antihypertensive angiotensin-II antagonist. Cardiovasc Drug Rev 1995; 13 (3): 230-50
-
(1995)
Cardiovasc Drug Rev
, vol.13
, Issue.3
, pp. 230-250
-
-
Criseione, L.1
Bradley, W.A.2
Bühlmayer, P.3
-
9
-
-
0028019601
-
Characterization of contractile endothelin and angiotensin receptors in human resistance arteries: Evidence for two endothelin and one angiotensin receptor
-
Oct 28
-
Tschudi MR, Luscher TF, Characterization of contractile endothelin and angiotensin receptors in human resistance arteries: evidence for two endothelin and one angiotensin receptor. Biochem Biophys Res Commun 1994 Oct 28: 204: 685-90
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 685-690
-
-
Tschudi, M.R.1
Luscher, T.F.2
-
10
-
-
0012298753
-
Single- and multipledose phase I trials with the angiotensin II antagonist valsartan
-
Dec
-
Müller P, Flesch G, de Gasparo M. et al. Single- and multipledose phase I trials with the angiotensin II antagonist valsartan [abstract]. J Hypertens 1993 Dec: 11 Suppl. 5: S459-60
-
(1993)
J Hypertens
, vol.11
, Issue.5 SUPPL.
-
-
Müller, P.1
Flesch, G.2
De Gasparo, M.3
-
11
-
-
0028117856
-
Angiotensin II receptor blockade with single doses of valsartan in healthy, normotensive subjects
-
Müller P. Cohen T, de Gasparo M. et al. Angiotensin II receptor blockade with single doses of valsartan in healthy, normotensive subjects. Eur J Clin Pharmacol 1994; 47 (3): 231-45
-
(1994)
Eur J Clin Pharmacol
, vol.47
, Issue.3
, pp. 231-245
-
-
Müller, P.1
Cohen, T.2
De Gasparo, M.3
-
12
-
-
0009670824
-
The pressor inhibitory effect of angiotensin-II antagonist (valsartan, CGP 48933) on angiotensin-II infusions in healthy subjects
-
Apr
-
Harb G, Morgan JM. Prasad P, et al. The pressor inhibitory effect of angiotensin-II antagonist (valsartan, CGP 48933) on angiotensin-II infusions in healthy subjects [abstraet]. J Invest Med 1995 Apr; 43 Suppl. 2: 239A
-
(1995)
J Invest Med
, vol.43
, Issue.2 SUPPL.
-
-
Harb, G.1
Morgan, J.M.2
Prasad, P.3
-
13
-
-
8544235265
-
Valsartan, a new angiotensin II receptor blocker: Tolerabilily and effect on renal function in treated hypertensive patients with stable renal insufficiency (protocol 26)
-
Data on file
-
Faulhaber HD, Stein G. Jansa U, et al. Valsartan, a new angiotensin II receptor blocker: Tolerabilily and effect on renal function in treated hypertensive patients with stable renal insufficiency (protocol 26). Novartis. 1997. (Data on file)
-
(1997)
Novartis
-
-
Faulhaber, H.D.1
Stein, G.2
Jansa, U.3
-
14
-
-
8544237290
-
Valsartan, a new angiotensin II receptor antagonist. Tolerability and effects on renal function in patients with renovascular arterial hypertension (protocol 25)
-
Data on file
-
Arzilli F, Favilla S, Motolese M, et al. Valsartan, a new angiotensin II receptor antagonist. Tolerability and effects on renal function in patients with renovascular arterial hypertension (protocol 25). Novartis. 1997. (Data on file)
-
(1997)
Novartis
-
-
Arzilli, F.1
Favilla, S.2
Motolese, M.3
-
15
-
-
8544238062
-
The effects of valsartan on mesenteric resistance vessel structure, heart weight and blood pressure in the NZ GH rat
-
Dec
-
Warman LP, Griffin MA, Ledingham JM, et al. The effects of valsartan on mesenteric resistance vessel structure, heart weight and blood pressure in the NZ GH rat [abstract]. 28th Annu Sci Meet ASCEPT 1994 Dec: 1: 123
-
(1994)
28th Annu Sci Meet ASCEPT
, vol.1
, pp. 123
-
-
Warman, L.P.1
Griffin, M.A.2
Ledingham, J.M.3
-
16
-
-
8544220003
-
A comparison of the effects of valsartan and enalapril on blood pressure and LV mass in New Zealand GH-rats
-
Dec
-
Pham LTV, Ledingham JM, Cross MA, et al. A comparison of the effects of valsartan and enalapril on blood pressure and LV mass in New Zealand GH-rats [abstract]. 28th Annu Sci Meet ASCEPT 1994 Dec; 1: 97
-
(1994)
28th Annu Sci Meet ASCEPT
, vol.1
, pp. 97
-
-
Pham, L.T.V.1
Ledingham, J.M.2
Cross, M.A.3
-
17
-
-
8544269654
-
Absolute bioavailability and pharmacokinetics of valsartan, an angiotensin II receptor antagonist, in man
-
Data on file
-
Flesch G, Mueller P, Lloyd P. Absolute bioavailability and pharmacokinetics of valsartan, an angiotensin II receptor antagonist, in man. Novartis, 1996. (Data on file)
-
(1996)
Novartis
-
-
Flesch, G.1
Mueller, P.2
Lloyd, P.3
-
18
-
-
8544220702
-
Pharmacokinetics and pharmacodynamic effects of the angiotensin II antagonist valsartan at steady state in healthy, normotensive sujects
-
In press
-
Müller P, Flesch G, de Gasparo M, et al. Pharmacokinetics and pharmacodynamic effects of the angiotensin II antagonist valsartan at steady state in healthy, normotensive sujects. Eur J Pharmacol. In press
-
Eur J Pharmacol
-
-
Müller, P.1
Flesch, G.2
De Gasparo, M.3
-
19
-
-
0030896929
-
Protein binding in plasma of valsartan, a new angiotensin II receptor antagonist
-
Colussi DM, Parisot C, Rossolino ML, et al. Protein binding in plasma of valsartan, a new angiotensin II receptor antagonist. J Clin Pharmacol 1997; 37-. 214-21
-
(1997)
J Clin Pharmacol
, vol.37
, pp. 214-221
-
-
Colussi, D.M.1
Parisot, C.2
Rossolino, M.L.3
-
20
-
-
0000188326
-
Plasma concentrations and antihypertensive effect of 10 to 160 mg doses of valsartan (VAL) in hypertensive patients
-
Oct
-
Kalbag J, Prasad P, Redalieu E, et al. Plasma concentrations and antihypertensive effect of 10 to 160 mg doses of valsartan (VAL) in hypertensive patients [abstract]. Pharm Res 1994 Oct: 11 Suppl.: S367
-
(1994)
Pharm Res
, vol.11
, Issue.SUPPL.
-
-
Kalbag, J.1
Prasad, P.2
Redalieu, E.3
-
21
-
-
0031022244
-
14C]-radiolabelled valsartan in healthy male volunteers after a single oral dose
-
14C]-radiolabelled valsartan in healthy male volunteers after a single oral dose. Xenobiotica 1997; 27(1): 59-71
-
(1997)
Xenobiotica
, vol.27
, Issue.1
, pp. 59-71
-
-
Waldmeier, F.1
Flesch, G.2
Müller, P.3
-
22
-
-
8544271196
-
Pharmacokinetics of valsartan in patients with liver disease
-
Data on file
-
Brookman LJ, Rolan PE, Benjamin IS, et al. Pharmacokinetics of valsartan in patients with liver disease. Novartis, 1996. (Data on file)
-
(1996)
Novartis
-
-
Brookman, L.J.1
Rolan, P.E.2
Benjamin, I.S.3
-
23
-
-
0030893274
-
Effect of renal function on the pharmacokinetics of valsartan
-
Prasad P, Mangat S, Choi L, et al. Effect of renal function on the pharmacokinetics of valsartan. Clin Drug Invest 1997: 13 (4): 207-14
-
(1997)
Clin Drug Invest
, vol.13
, Issue.4
, pp. 207-214
-
-
Prasad, P.1
Mangat, S.2
Choi, L.3
-
24
-
-
0009328595
-
The effect of age on the Pharmacokinetics of valsartan
-
Sioufi A, Marfil F, Jaouen A, et al. The effect of age on the Pharmacokinetics of valsartan [abstract]. Eur J Drug Metab Pharmacokinet 1996 (Special issue): 86
-
(1996)
Eur J Drug Metab Pharmacokinet
, Issue.SPEC. ISSUE
, pp. 86
-
-
Sioufi, A.1
Marfil, F.2
Jaouen, A.3
-
25
-
-
0028352782
-
Angiotensin-II antagonist CGP-48933 (valsartan): Results of a double-blind, placebocontrolled multicenter study
-
May
-
Strödter D, Zeissig I, Heath R, et al. Angiotensin-II antagonist CGP-48933 (valsartan): results of a double-blind, placebocontrolled multicenter study [in German]. Nieren Hoch 1994 May; 23: 217-20
-
(1994)
Nieren Hoch
, vol.23
, pp. 217-220
-
-
Strödter, D.1
Zeissig, I.2
Heath, R.3
-
26
-
-
0027399060
-
The Fifth Report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure (JNC V)
-
Jan 25
-
Joint National Committee on Detection Evaluation and Treatment of High Blood Pressure. The Fifth Report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure (JNC V). Arch Intern Med 1993 Jan 25; 153: 154-83
-
(1993)
Arch Intern Med
, vol.153
, pp. 154-183
-
-
-
27
-
-
0027274762
-
1993 Guidelines for the managment of mild hypertension: Memorandum from a World Health Organization/International Society of Hypertension meeting
-
World Health Organization Guidelines Subcommittee. 1993 Guidelines for the managment of mild hypertension: memorandum from a World Health Organization/International Society of Hypertension meeting. J Hypertens 1993; 11: 905-18
-
(1993)
J Hypertens
, vol.11
, pp. 905-918
-
-
-
28
-
-
0029969837
-
The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension
-
Oparil S, Dyke S, Harris F, et al. The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension. Clin Ther 1996; 18 (5): 797-810
-
(1996)
Clin Ther
, vol.18
, Issue.5
, pp. 797-810
-
-
Oparil, S.1
Dyke, S.2
Harris, F.3
-
29
-
-
0348170069
-
Results of a pilot dose-ranging trial of valsartan in patients with essential hypertension
-
Apr
-
Chrysant SG, Holtzman J, Lewin A, et al. Results of a pilot dose-ranging trial of valsartan in patients with essential hypertension [abstract]. Am J Hypertens 1996 Apr; 9: 121A (Pt 2)
-
(1996)
Am J Hypertens
, vol.9
, Issue.2 PART
-
-
Chrysant, S.G.1
Holtzman, J.2
Lewin, A.3
-
30
-
-
8544243036
-
Long term safety, tolerability and efficacy of valsartan: Results from one and two year trials (protocol 31E/11E)
-
Data on file
-
Chen S, James D. Hester A, et al. Long term safety, tolerability and efficacy of valsartan: results from one and two year trials (protocol 31E/11E). Novartis, 1996. (Data on file)
-
(1996)
Novartis
-
-
Chen, S.1
James, D.2
Hester, A.3
-
31
-
-
8544268913
-
Valsartan, a new angiotensin II antagonist: Antihypertensive effects over 24 hours (protocol 31 ABPM)
-
Data on file
-
Neutel J, Weber M, Pool J, et al. Valsartan, a new angiotensin II antagonist: antihypertensive effects over 24 hours (protocol 31 ABPM). Novartis. 1996. (Data on file)
-
(1996)
Novartis
-
-
Neutel, J.1
Weber, M.2
Pool, J.3
-
32
-
-
8544221408
-
Valsartan: Long term efficacy and tolerability compared to lisinopril in elderly patients with essential hypertension (protocol 28)
-
Data on file
-
Valsartan: long term efficacy and tolerability compared to lisinopril in elderly patients with essential hypertension (protocol 28). Novartis. 1996. (Data on file)
-
(1996)
Novartis
-
-
-
33
-
-
84877071134
-
Valsartan. a new angiotensin II antagonist for the treatment of essential hypertension. Efficacy, tolerabilty and safely compared to an angiotensin converting enzyme inhibitor lisinopril (protocol 50)
-
Data on file
-
Black HR. Graff A, Shute D, et al. Valsartan. a new angiotensin II antagonist for the treatment of essential hypertension. Efficacy, tolerabilty and safely compared to an angiotensin converting enzyme inhibitor lisinopril (protocol 50). Novartis, 1997. (Data on file)
-
(1997)
Novartis
-
-
Black, H.R.1
Graff, A.2
Shute, D.3
-
34
-
-
3643132971
-
A comparison of the efficacy and tolerability of a new angiotensin II antagonist, valsartan. with enalapril in patients with mild-to-moderate essential hypertension
-
Aug
-
Grün A, Francillon A, Bodin F, et al. A comparison of the efficacy and tolerability of a new angiotensin II antagonist, valsartan. with enalapril in patients with mild-to-moderate essential hypertension [abstract]. Eur Heart J 1995 Aug; 16 Suppl.: 61
-
(1995)
Eur Heart J
, vol.16
, Issue.SUPPL.
, pp. 61
-
-
Grün, A.1
Francillon, A.2
Bodin, F.3
-
35
-
-
0029775814
-
Valsartan. a new angiotensin II antagonist for the treatment of essential hypertension: Efficacy and safety compared with placebo and enalapril
-
Holwerda NJ, Fogari R, Angeli P, et al. Valsartan. a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. J Hypertens 1996; 14: 1147-51
-
(1996)
J Hypertens
, vol.14
, pp. 1147-1151
-
-
Holwerda, N.J.1
Fogari, R.2
Angeli, P.3
-
36
-
-
8544244418
-
Valsartan. a new angiotensin II antagonist: Efficacy and tolerability compared with an angiotensin converting enzyme inhibitor enalapril in essential hypertension
-
In press
-
Mallion J-M, Boutelant S, Chabaux P, et al. Valsartan. a new angiotensin II antagonist: efficacy and tolerability compared with an angiotensin converting enzyme inhibitor enalapril in essential hypertension. Blood Pres Mon. In press
-
Blood Pres Mon
-
-
Mallion, J.-M.1
Boutelant, S.2
Chabaux, P.3
-
37
-
-
0002887081
-
Comparison of the efficacy of two angiotensin II antagonists, valsartan and losartan. in essential hypertension
-
Oddou-Stock P, Gatlin M, Kohi P, et al. Comparison of the efficacy of two angiotensin II antagonists, valsartan and losartan. in essential hypertension [abstract]. Am J Hypertens 1997; 10 (4): 84A
-
(1997)
Am J Hypertens
, vol.10
, Issue.4
-
-
Oddou-Stock, P.1
Gatlin, M.2
Kohi, P.3
-
38
-
-
0030925703
-
Valsartan. a new angiotensin II antagonist for the treatment of essential hypetension: Efficacy and safety compared to hydrochlorothiazide
-
Hegner G, Faust G, Freytag F, et al. Valsartan. a new angiotensin II antagonist for the treatment of essential hypetension: efficacy and safety compared to hydrochlorothiazide. Eur J Pharmacol 1997; 52: 173-177
-
(1997)
Eur J Pharmacol
, vol.52
, pp. 173-177
-
-
Hegner, G.1
Faust, G.2
Freytag, F.3
-
39
-
-
0029807227
-
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: A comparative study of the efficacy and safety against amlodipine
-
Sep
-
Corea L, Cardoni O, Fogari R, et al. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine. Clin Pharmacol Ther 1996 Sep; 60: 341-6
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 341-346
-
-
Corea, L.1
Cardoni, O.2
Fogari, R.3
-
40
-
-
4244049623
-
Comparison of the angiotensin II antagonist valsartan with the β-blocker atenolol in patients with severe essential hypertension
-
Cifkova R, Botteri F, Mann J, et al. Comparison of the angiotensin II antagonist valsartan with the β-blocker atenolol in patients with severe essential hypertension [abstract]. Am J Hypertens 1997; 10 (4): 114A
-
(1997)
Am J Hypertens
, vol.10
, Issue.4
-
-
Cifkova, R.1
Botteri, F.2
Mann, J.3
-
41
-
-
0030668490
-
Efficacy and tolerability of valsartan compared with lisinopril in patients with hypertension and renal insufficiency
-
In press
-
Perico N, Spormann D, Peruzzi E, et al. Efficacy and tolerability of valsartan compared with lisinopril in patients with hypertension and renal insufficiency. Clin Drug Invest. In press
-
Clin Drug Invest
-
-
Perico, N.1
Spormann, D.2
Peruzzi, E.3
-
42
-
-
8544269653
-
Valsartan facts and figures
-
Data on file
-
Valsartan facts and figures. Novartis, 1996. (Data on file)
-
(1996)
Novartis
-
-
-
43
-
-
0030980604
-
Valsartan. a new angiotensin II receptor antagonist: A double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide
-
Benz J, Oshrain C, Henry D. et al. Valsartan. a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide. J Clin Pharmacol 1997; 37: 101-7
-
(1997)
J Clin Pharmacol
, vol.37
, pp. 101-107
-
-
Benz, J.1
Oshrain, C.2
Henry, D.3
-
45
-
-
0024311243
-
Blood pressure as a risk factor for cardiovascular disease. The Framingham study - 30 years of follow-up
-
May
-
Stokes J, Kannel WB, Wolf PA, et al. Blood pressure as a risk factor for cardiovascular disease. The Framingham study - 30 years of follow-up. Hypertension 1989 May; 13 Suppl. 5: 133-5
-
(1989)
Hypertension
, vol.13
, Issue.5 SUPPL.
, pp. 133-135
-
-
Stokes, J.1
Kannel, W.B.2
Wolf, P.A.3
-
46
-
-
0029153162
-
Management guidelines for hypertension: Is anyone taking notice?
-
Swales JD. Management guidelines for hypertension: is anyone taking notice? J Hum Hypertens 1995; 9: S9-S13
-
(1995)
J Hum Hypertens
, vol.9
-
-
Swales, J.D.1
-
47
-
-
0029971915
-
Choice of initial therapy for hypertension
-
May 22-29
-
Kaplan NM. Gifford Jr RW. Choice of initial therapy for hypertension. JAMA 1996 May 22-29; 275: 1577-80
-
(1996)
JAMA
, vol.275
, pp. 1577-1580
-
-
Kaplan, N.M.1
Gifford Jr., R.W.2
-
48
-
-
0029932496
-
Losartan potassium: A review of its pharmacology, clinical efficacy and tolerability in the management of hypertension
-
May
-
Goa KL, Wagstaff AJ, Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension. Drugs 1996 May; 51: 820-45
-
(1996)
Drugs
, vol.51
, pp. 820-845
-
-
Goa, K.L.1
Wagstaff, A.J.2
-
49
-
-
0027145599
-
New therapeutic agents in the management of hypertension: Angiotensin II-receptor antagonists and renin inhibitors
-
Dec
-
Foote EF, Halstenson CE. New therapeutic agents in the management of hypertension: angiotensin II-receptor antagonists and renin inhibitors. Ann Pharmacother 1993 Dec: 27: 1495-503
-
(1993)
Ann Pharmacother
, vol.27
, pp. 1495-1503
-
-
Foote, E.F.1
Halstenson, C.E.2
-
50
-
-
0028840484
-
Effect of angiotensin II blockade on cardiac hypertrophy and remodelling: A review
-
Nov
-
Dahlöf B. Effect of angiotensin II blockade on cardiac hypertrophy and remodelling: a review. J Hum Hypertens 1995 Nov; 9 Suppl. 5: 37-44
-
(1995)
J Hum Hypertens
, vol.9
, Issue.5 SUPPL.
, pp. 37-44
-
-
Dahlöf, B.1
|