Absolute ProGRP quantification in a clinical relevant concentration range using LC-MS/MS and a comprehensive internal standard

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 13, 2009, Pages 1359-1365

  Winther, Bjørn ^a   Moi, Petter ^a   Nordlund, Marianne S ^b   Lunder, Niclas ^c   Paus, Elisabeth ^b   Reubsaet, J Léon E ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c DIAKONHJEMMET HOSPITAL   (Norway)

Author keywords

Absolute quantification; Biomarker; Internal standard; LC MS MS; MRM; NHS acetylation; ProGRP; Signature peptide; Small cell lung cancer; Tryptic peptide

Indexed keywords

ABSOLUTE QUANTIFICATION; INTERNAL STANDARD; LC-MS/MS; MRM; NHS-ACETYLATION; PROGRP; SIGNATURE PEPTIDE; SMALL CELL LUNG CANCER; TRYPTIC PEPTIDE;

ACETONITRILE; ACETYLATION; AMINES; AMINO ACIDS; BIOLOGICAL ORGANS; BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; STANDARDS;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

ACETONITRILE; ASPARAGINYLLEUCYLLEUCYLGLYCYLLEUCYLISOLEUCYLGLUTAMYLALANYLLYSINE; BIOLOGICAL MARKER; LYSINE; PEPTIDE; PROGASTRIN RELEASING PEPTIDE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; HUMAN; LIQUID CHROMATOGRAPHY; LUNG SMALL CELL CANCER; PRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ASSAY; STANDARD; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; HUMANS; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; REFERENCE STANDARDS; TANDEM MASS SPECTROMETRY;

EID: 64149102099     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.12.023     Document Type: Article

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