Diet-related telomere shortening and chromosome stability

Mutagenesis

Volumn 27, Issue 1, 2012, Pages 49-57

  Marcon, Francesca ^a   Siniscalchi, Ester ^a   Crebelli, Riccardo ^a   Saieva, Calogero ^b   Sera, Francesco ^b   Fortini, Paola ^a   Simonelli, Valeria ^a   Palli, Domenico ^b  

^a Italian National Health Institute   (Italy)

^b CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; ARTICLE; CHROMOSOMAL INSTABILITY; CHROMOSOME SIZE; DIETARY INTAKE; FEMALE; FOOD INTAKE; GENOTYPE; HUMAN; LYMPHOCYTE; MALE; NORMAL HUMAN; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT; SMOKING; TELOMERE LENGTH; VEGETABLE;

ANTIOXIDANTS; BETA CAROTENE; BIOLOGICAL MARKERS; CHROMOSOMAL INSTABILITY; DIET; FEMALE; GENOTYPE; HUMANS; LIFE STYLE; LYMPHOCYTES; MALE; MICRONUCLEUS TESTS; MICRONUTRIENTS; MIDDLE AGED; OXIDATIVE STRESS; QUESTIONNAIRES; SEQUENCE ANALYSIS, DNA; SMOKING; TELOMERE; TELOMERE SHORTENING; VEGETABLES;

EID: 84555195034     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger056     Document Type: Article

References (67)

1. Blackburn, E. H. (1991) Structure and function of telomeres. Nature, 350, 569573.
2. Palm, W. and de Lange, T. (2008) How shelterin protects mammalian telomeres. Annu. Rev. Genet., 42, 301-334.
3. O'Sullivan, R. J. and Karlseder, J. (2010) Telomeres: Protecting chromosomes against genome instability. Nat. Rev. Mol. Cell. Biol., 11, 171-181.
4. Makarov, V. L., Hirose, Y. and Langmore, J. P. (1997) Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88, 657-666. (Pubitemid 27152408)
5. Cech, T. R. (2004) Beginning to understand the end of the chromosome. Cell, 116, 273-279. (Pubitemid 38167317)
6. Greider, C. W. and Blackburn, E. H. (1996) Telomeres, telomerase and cancer. Sci. Am., 274, 92-97.
7. Reddel, R. R. and Bryan, T. M. (2003) Alternative lengthening of telomeres: Dangerous road less travelled. Lancet, 361, 1840-1841. (Pubitemid 36645174)
8. Cawthon, R. M., Smith, K. R., O'Brien, E., Sivatchenko, A. and Kerber, R. A. (2003) Association between telomere length in blood and mortality in people aged 60 years or older. Lancet, 361, 393-395. (Pubitemid 36164975)
9. Martin-Ruiz, C., Dickinson, H. O., Keys, B., Rowan, E., Kenny, R. A. and Von Zglinicki, T. (2006) Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann. Neurol., 60, 174-180. (Pubitemid 44182392)
10. Wu, X., Amos, C. I., Zhu, Y., Zhao, H., Grossman, B. H., Shay, J. W., Luo, S., Hong, W. K. and Spitz, M. R. (2003) Telomere dysfunction: A potential cancer predisposition factor. J. Natl. Cancer Inst., 95, 1211-1218. (Pubitemid 37069551)
11. Vasa-Nicotera, M., Brouilette, S., Mangino, M. et al. (2005) Mapping of a major locus that determines telomere length in humans. Am. J. Hum. Genet., 76, 147-151. (Pubitemid 40023773)
12. Andrew, T., Aviv, A., Falchi, M. et al. (2006) Mapping genetic loci that determine leukocyte telomere length in a large sample of unselected female sibling pairs. Am. J. Hum. Genet., 78, 480-486. (Pubitemid 43291229)
13. Cherkas, L. F., Hunkin, J. L., Kato, B. S. et al. (2008) The association between physical activity in leisure time and leukocyte telomere length. Arch. Intern. Med., 168, 154-158. (Pubitemid 351185881)
14. Valdes, A. M., Andrew, T., Gardner, J. P., Kimura, M., Oelsner, E., Cherkas, L. F., Aviv, A. and Spector, T. D. (2005) Obesity, cigarette smoking, and telomere length in women. Lancet, 366, 662-664. (Pubitemid 41176019)
15. Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D. and Cawthon, R. M. (2004) Accelerated telomere shortening in response to life stress. Proc. Natl Acad. Sci. U. S. A., 101, 17312-17315. (Pubitemid 39627816)
16. von Zglinicki, T. and Martin-Ruiz, C. M. (2005) Telomeres as biomarkers for ageing and age-related diseases. Curr. Mol. Med., 5, 197-203. (Pubitemid 40601647)
17. Houben, J. M., Moonen, H. J., van Schooten, F. J. and Hageman, G. J. (2008) Telomere length assessment: Biomarker of chronic oxidative stress? Free Radic. Biol. Med., 44, 235-246.
18. Xu, Q., Parks, C. G., DeRoo, L. A., Cawthon, R. M., Sandler, D. P. and Chen, H. (2009) Multivitamin use and telomere length in women. Am. J. Clin. Nutr., 89, 1857-1863.
19. Bull, C. F., O'Callaghan, N. J., Mayrhofer, G. and Fenech, M. F. (2009) Telomere length in lymphocytes of older South Australian men may be inversely associated with plasma homocysteine. Rejuvenation Res., 12, 341-349.
20. Cassidy, A., De Vivo, I., Liu, Y., Han, J., Prescott, J., Hunter, D. J. and Rimm, E. B. (2010) Associations between diet, lifestyle factors, and telomere length in women. Am. J. Clin. Nutr., 91, 1273-1280.
21. Ames, B. N. (2006) Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. Proc. Natl Acad. Sci. U. S. A., 103, 17589-17594. (Pubitemid 44852204)
22. Bull, C. and Fenech, M. (2008) Genome-health nutrigenomics and nutrigenetics: Nutritional requirements or 'nutriomes' for chromosomal stability and telomere maintenance at the individual level. Proc. Nutr. Soc., 67, 146-156. (Pubitemid 351543396)
23. Blount, B. C., Mack, M. M., Wehr, C. M., MacGregor, J. T., Hiatt, R. A., Wang, G., Wickramasinghe, S. N., Everson, R. B. and Ames, B. N. (1997) Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage. Proc. Natl Acad. Sci. U. S. A., 94, 3290-3295.
24. Maret, W. and Krezel, A. (2007) Cellular zinc and redox buffering capacity of metallothionein/thionein in health and disease. Mol. Med., 13, 371-375. (Pubitemid 47378138)
25. Gonzalo, S., Jaco, I., Fraga, M. F., Chen, T., Li, E., Esteller, M. and Blasco, M. A. (2006) DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat. Cell Biol., 8, 416-424.
26. Renaud, S., Loukinov, D., Abdullaev, Z., Guilleret, I., Bosman, F. T., Lobanenkov, V. and Benhattar, J. (2007) Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. Nucleic Acids Res., 35, 1245-1256. (Pubitemid 46522976)
27. Fenech, M. F. (2010) Dietary reference values of individual micronutrients and nutriomes for genome damage prevention: Current status and a road map to the future. Am. J. Clin. Nutr., 91, 1438S-1454S.
28. Williams, E. S., Klingler, R., Ponnaiya, B., Hardt, T., Schrock, E., Lees- Miller, S. P., Meek, K., Ullrich, R. L. and Bailey, S. M. (2009) Telomere dysfunction and DNA-PKcs deficiency: Characterization and consequence. Cancer Res., 69, 2100-2107.
29. Yasaei, H. and Slijepcevic, P. (2010) Defective Artemis causes mild telomere dysfunction. Genome Integr., 1, 3.
30. Marcon, F., Palli, D., Zufferli, A., Mazzoli, E., Siniscalchi, E., Sera, F., Saieva, C. and Crebelli, R. (2009) Evaluation of radiation-induced chromosome instability in subjects with a family history of gastric cancer. Biomarkers, 14, 226-234.
31. Pisani, P., Faggiano, F., Krogh, V., Palli, D., Vineis, P. and Berrino, F. (1997) Relative validity and reproducibility of a food frequency dietary questionnaire for use in the Italian EPIC centres. Int. J. Epidemiol., 26 (Suppl. 1), S152-S160. (Pubitemid 27129699)
32. Palli, D., Berrino, F., Vineis, P. et al. (2003) A molecular epidemiology project on diet and cancer: The EPIC-Italy Prospective Study. Design and baseline characteristics of participants. Tumori, 89, 586-593. (Pubitemid 38155535)
33. Pala, V., Sieri, S., Palli, D. et al. (2003) Diet in the Italian EPIC cohorts: Presentation of data and methodological issues. Tumori, 89, 594-607. (Pubitemid 38155536)
34. Salvini, S. (1997) A food composition database for epidemiological studies in Italy. Cancer Lett., 114, 299-300. (Pubitemid 27140136)
35. Kruk, P. A., Rampino, N. J. and Bohr, V. A. (1995) DNA damage and repair in telomeres: Relation to aging. Proc. Natl Acad. Sci. U. S. A., 92, 258-262.
36. Cherif, H., Tarry, J. L., Ozanne, S. E. and Hales, C. N. (2003) Ageing and telomeres: A study into organ-and gender-specific telomere shortening. Nucleic Acids Res., 31, 1576-1583. (Pubitemid 36304920)
37. Carere, A., Antoccia, A., Crebelli, R. et al. (1995) Genetic effects of petroleum fuels: Cytogenetic monitoring of gasoline station attendants. Mutat. Res., 332, 17-26.
38. Fenech, M. (2000) The in vitro micronucleus technique. Mutat. Res., 455, 81-95.
39. Baird, D. M. (2005) New developments in telomere length analysis. Exp. Gerontol., 40, 363-368. (Pubitemid 40775728)
40. Tarry-Adkins, J. L., Chen, J. H., Smith, N. S., Jones, R. H., Cherif, H. and Ozanne, S. E. (2009) Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets. FASEB J., 23, 1521-1528.
41. Guan, J. Z., Maeda, T., Sugano, M., Oyama, J., Higuchi, Y. and Makino, N. (2007) Change in the telomere length distribution with age in the Japanese population. Mol. Cell Biochem., 304, 353-360. (Pubitemid 47456884)
42. Harley, C. B., Futcher, A. B. and Greider, C. W. (1990) Telomeres shorten during ageing of human fibroblasts. Nature, 345, 458-460.
43. Shay, J. W. and Wright, W. E. (2000) Hayflick, his limit, and cellular ageing. Nat. Rev. Mol. Cell Biol., 1, 72-76.
44. Hsu, C. P., Hsu, N. Y., Lee, L. W. and Ko, J. L. (2006) Ets2 binding site single nucleotide polymorphism at the hTERT gene promoter-effect on telomerase expression and telomere length maintenance in non-small cell lung cancer. Eur. J. Cancer, 42, 1466-1474.
45. Matsubara, Y., Murata, M., Yoshida, T., Watanabe, K., Saito, I., Miyaki, K., Omae, K. and Ikeda, Y. (2006) Telomere length of normal leukocytes is affected by a functional polymorphism of hTERT. Biochem. Biophys. Res. Commun., 341, 128-131. (Pubitemid 43117395)
46. Jang, J. S., Choi, Y. Y., Lee, W. K. et al. (2008) Telomere length and the risk of lung cancer. Cancer Sci., 99, 1385-1389. (Pubitemid 351761728)
47. McGrath, M., Wong, J. Y., Michaud, D., Hunter, D. J. and De Vivo, I. (2007) Telomere length, cigarette smoking, and bladder cancer risk in men and women. Cancer Epidemiol. Biomarkers Prev., 16, 815-819. (Pubitemid 46650587)
48. Mirabello, L., Huang, W. Y., Wong, J. Y., Chatterjee, N., Reding, D., Crawford, E. D., De Vivo, I., Hayes, R. B. and Savage, S. A. (2009) The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging Cell, 8, 405-413.
49. Ocké, M. C., Bueno-de-Mesquita, H. B., Pols, M. A., Smit, H. A., van Staveren, W. A. and Kromhout, D. (1997) The Dutch EPIC food frequency questionnaire. II. Relative validity and reproducibility for nutrients. Int. J. Epidemiol., 26 (Suppl. 1), S49-S58. (Pubitemid 27129689)
50. von Zglinicki, T. (2002) Oxidative stress shortens telomeres. Trends Biochem. Sci., 27, 339-344. (Pubitemid 34756516)
51. Kawanishi, S. and Oikawa, S. (2004) Mechanism of telomere shortening by oxidative stress. Ann. N. Y. Acad. Sci., 1019, 278-284. (Pubitemid 38951320)
52. Serra, V., von Zglinicki, T., Lorenz, M. and Saretzki, G. (2003) Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening. J. Biol. Chem., 278, 6824-6830. (Pubitemid 36800672)
53. van Steensel, B., Smogorzewska, A. and de Lange, T. (1998) TRF2 protects human telomeres from end-to-end fusions. Cell, 92, 401-413. (Pubitemid 28093017)
54. Opresko, P. L., Fan, J., Danzy, S., Wilson, D. M., 3rd and Bohr, V. A. (2005) Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2. Nucleic Acids Res., 33, 1230-1239. (Pubitemid 41439916)
55. Petersen, S., Saretzki, G. and von Zglinicki, T. (1998) Preferential accumulation of single-stranded regions in telomeres of human fibroblasts. Exp. Cell Res., 239, 152160.
56. Stewart, S. A., Ben-Porath, I., Carey, V. J., O'Connor, B. F., Hahn, W. C. and Weinberg, R. A. (2003) Erosion of the telomeric single-strand overhang at replicative senescence. Nat. Genet., 33, 492-496. (Pubitemid 36390011)
57. Makpol, S., Zainuddin, A., Rahim, N. A., Yusof, Y. A. and Ngah, W. Z. (2010) Alphatocopherol modulates hydrogen peroxide-induced DNA damage and telomere shortening of human skin fibroblasts derived from differently aged individuals. Planta Med., 76, 869-875.
58. Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M. and Mazur, M. (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact., 160, 1-40. (Pubitemid 43227479)
59. Caballero, A., Ugidos, A., Liu, B. et al. (2011) Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing. Mol. Cell, 42, 390-400.
60. Fenech, M., Kirsch-Volders, M., Natarajan, A. T. et al. (2011) Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis, 26, 125-132.
61. Saltman, D., Morgan, R., Cleary, M. L. and de Lange, T. (1993) Telomeric structure in cells with chromosome end associations. Chromosoma, 102, 121-128. (Pubitemid 23040895)
62. Capper, R., Britt-Compton, B., Tankimanova, M., Rowson, J., Letsolo, B., Man, S., Haughton, M. and Baird, D. M. (2007) The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev., 21, 2495-2508. (Pubitemid 47529377)
63. Hemann, M. T., Strong, M. A., Hao, L. Y. and Greider, C. W. (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell, 107, 67-77. (Pubitemid 32972038)
64. Counter, C. M., Avilion, A. A., LeFeuvre, C. E., Stewart, N. G., Greider, C. W., Harley, C. B. and Bacchetti, S. (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11, 1921-1929.
65. Kimura, M., Barbieri, M., Gardner, J. P., Skurnick, J., Cao, X., van Riel, N., Rizzo, M. R., Paoliso, G. and Aviv, A. (2007) Leukocytes of exceptionally old persons display ultra-short telomeres. Am. J. Physiol. Regul. Integr. Comp. Physiol., 293, R2210-R2217. (Pubitemid 350224013)
66. Baird, D. M. (2008) Mechanisms of telomeric instability. Cytogenet. Genome Res., 122, 308-314.
67. Letsolo, B. T., Rowson, J. and Baird, D. M. (2010) Fusion of short telomeres in human cells is characterized by extensive deletion and microhomology, and can result in complex rearrangements. Nucleic Acids Res., 38, 1841-1852.