Dried blood spot (DBS) evaluation of compounds with differing physiochemical properties and card lots using LC-MS/MS

American Pharmaceutical Review

Volumn 14, Issue 7, 2011, Pages 34-40

  Pham, Roger ^a   Moore, Earl ^a   Wells, Mary C ^a   Xu, Guifen ^a   Bruenner, Bernd A ^a   James, Christopher A ^a   Wong, Philip ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONCENTRATION (PARAMETERS); DRIED BLOOD SPOT TESTING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PHYSICAL CHEMISTRY; QUALITY CONTROL; RAT;

EID: 84555190848     PISSN: 10998012     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Li W, Tse FLS. Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomed. Chromatogr. 24(1), 49-65 (2010).
2. Edelbroek P.M., Heijden J., Stolk L.M., Dried Blood Spot Methods in Therapeutic Drug Monitoring: Methods, Assays, and Pitfalls, Therapeutic Drug Monitoring, 31 (2009) 327-336.
3. P. Patel, Mulla H, Tanna S, Pandya H, Facilitating pharmacokinetic studies in children: a new use of dried blood spots. Arch. Dis. Child. 95(6), 484-487 (2010).
4. Pandya HC, Spooner N, Mulla H, Dried blood spots, pharmacokinetic studies and better medicines for children. Bioanalysis 3(7), 779-786 (2011).
5. Guthrie R., Susi A., A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants, Pediatrics 32(3), 338-343 (1963).
6. Johannessen A., Dried blood spots in HIV monitoring: applications in resources-limited settings, Bioanalysis. 2, 1893-1908 (2010).
7. Wong P, Pham R, Whitely C, Soto M, Salyers K, James C, Bruenner B. A. Pharma. Biomed. Anal. 56(3), 604-608 (2011).
8. Uyeda C, Pham R, Fide S, Henne K, Xu G, Soto M, James C, Wong P. Application of automated dried blood spot sampling and LC-MS/MS for pharmacokinetic studies of AMG 517 in rats. Bioanalysis 3 (20), 2349-2356 (2011).
9. Spooner N, Lad R, Barfield M, Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: considerations for the validation of a quantitative bioanalytical method. Anal. Chem. 81,1557-1563 (2009).
10. Amsterdam PV, Waldrop C. The application of dried blood spot sampling in global clinical trials. Bioanalysis 2(11), 1783-1786 (2010).
11. D'Arienzo CJ, Ji QC, Discenza I et al. DBS sampling can be used to stabilize prodrugs in drug discovery rodent studies without the addition of esterase inhibitors. Bioanalysis, 2(8), 1415-1422 (2010).
12. Bowen CL, Cades J, Volpatti J, Licea-Perez, Evans CA. Feasibility of dried blood and plasma spots to the enhanced stability of glucuronide stability, Presented at the 59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO, June 5-9, 2011.
13. Denniff P., Spooner N., The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs, Bioanalysis. 2(8), 1385-1395 (2010).
14. Phadnis R, Moore E, Pham R et al. Application of DBS to the pharmacokinetic evaluation of compounds with various blood-to-plasma ratios using LC-MS/MS. Presented at the 59th ASMS Conference on Mass Spectrometry and Allied Topics, Denver, CO, June 5-9, 2011.
15. Rowland M, Emmons GT, Use of dried blood spots in drug development: Pharmacokinetic considerations, AAPS J. 12(3), 290-293 (2010).
16. Emmons G, Rowland M, Pharmacokinetic considerations as to when to use dried blood spot sampling, Bioanalysis 2(11), 1791-1796 (2010).
17. Wickremsinhe ER, Abdul BG, Huang NH et al., Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies. Bioanalysis 3(14), 1635-1646 (2011).
18. Blessborn D., Romsing S., Bergquvist Y., Lindegardh N., Assay for screening for six antimalarial drugs and one metabolite using dried blood spot sampling, sequential extraction and ion-trap detection, Bioanalysis. 2(11), 1839-1847 (2010).
19. Ertl P, Rohde B, Selzer P, Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties. J. Med. Chem. 43, 3714-3717 (2000).
20. Ertl P. Polar Surface Area, in Molecular Drug Properties, R. Mannhold (ed), Wiley-VCH, pp 111-126, 2007.
21. Kehler JR, Bowen CL, Boram S, Evans CA. Application of DBS for quantitative assessment of the peptides Exendin-4; comparison of plasma and DBS method by UHPLC-MS/MS. Bioanalysis, 2(8), 1461-1468 (2010).