Dried blood spot sampling: Coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies

Bioanalysis

Volumn 3, Issue 14, 2011, Pages 1635-1646

  Wickremsinhe, Enaksha R ^a   Abdul, Basira G ^a   Huang, Naijia H ^a   Richard, John W ^a,b   Hanes, Jennifer L ^b   Ruterbories, Kenneth J ^a   Perkins, Everett J ^a   Chaudhary, Ajai K ^a,c  

^a ELI LILLY AND COMPANY   (United States)

^b Covance Laboratories Ltd ^*  (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LLY 1; LLY 3; LLY 4; LLY 8; NEW DRUG; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BLOOD VOLUME; CONTROLLED STUDY; DRIED BLOOD SPOT; DRUG STABILITY; ENVIRONMENTAL TEMPERATURE; FEASIBILITY STUDY; FLOW RATE; IN VIVO STUDY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MATHEMATICAL ANALYSIS; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

BLOOD PROTEINS; DRIED BLOOD SPOT TESTING; FEASIBILITY STUDIES; HUMANS; PHARMACEUTICAL PREPARATIONS; PLASMA;

EID: 79960485984     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.124     Document Type: Article

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