Molecular docking and competitive binding study discovered different binding modes of microsomal prostaglandin e synthase-1 inhibitors

Journal of Chemical Information and Modeling

Volumn 51, Issue 12, 2011, Pages 3254-3261

  He, Shan ^b   Lai, Luhua ^a,b  

^a PEKING UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DISEASES; LIPIDS; MOLECULAR MODELING;

BINDING MECHANISMS; COMPETITIVE BINDING; INHIBITION MECHANISMS; INHIBITORY MECHANISM; MICROSOMAL PROSTAGLANDIN; MOLECULAR DOCKING; STRUCTURAL MODELING; THERAPEUTIC TARGETS;

BINDING SITES;

ENZYME INHIBITOR; ISOMERASE; PROSTAGLANDIN E SYNTHASE;

ARTICLE; BINDING COMPETITION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; HUMAN; METABOLISM; MICROSOME; PROTEIN BINDING;

BINDING SITES; BINDING, COMPETITIVE; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICROSOMES; MODELS, MOLECULAR; PROTEIN BINDING;

EID: 84555169343     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci200427k     Document Type: Article

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