Effect of intrauterine morphine sulfate exposure on cerebellar histomorphological changes in neonatal mice

Folia Neuropathologica

Volumn 49, Issue 4, 2011, Pages 328-334

  Ghafari, Soraya ^a   Roshandel, Danial ^a   Golalipour, Mohammad Jafar ^a  

^a GOLESTAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cerebellum; Cortex; Morphine sulfate; Mouse; Purkinje cells

Indexed keywords

MORPHINE SULFATE;

ANIMAL CELL; ARTICLE; CELL DENSITY; CEREBELLUM; CEREBELLUM CORTEX; CONTROLLED STUDY; FEMALE; FETUS; FETUS WEIGHT; HISTOPATHOLOGY; MORPHOMETRICS; MOUSE; NEUROTOXICITY; NEWBORN; NONHUMAN; PREGNANCY; PRENATAL DRUG EXPOSURE; PURKINJE CELL;

EID: 84455162094     PISSN: 16414640     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Atici S, Cinel L, Cinel I, Doruk N, Aktekin M, Akca A, Camdeviren H, Oral U. Opioid neurotoxicity: comparison of morphine and tramadol in an experimental rat model. Int J Neurosci 2004; 114: 1001-1011. (Pubitemid 38923893)
2. Atta FAM. Depressant of morphine on cellular composition of lymphoid tissues and cerebellum in rats. J Egypt Ger Soc Zool 2002; 39: 411-438.
3. Bekheet SH, Saker SA, Abdel-Kader AM, Younis AEA. Histopathological and biochemical changes of morphine sulphate administration on the cerebellum of albino rats. Tissue Cell 2010; 42: 165-175.
4. Cadet P, Rasmussen M, Zhu W, Tonnesen E, Mantione KJ, Stefano GB. Endogenous morphinergic signaling and tumor growth Front. Biosci 2004; 9: 3176-3186.
5. Cheng N, Quimby FW, Lei XG. Impacts of glutathione peroxidase-1 knockout on the protection by injected selenium against the pro-oxidant-induced liver aponecrosis and signaling in selenium deficient mice. Free Radic Biol Med 2003; 34: 918-927. (Pubitemid 36316076)
6. Chooa RE, Huestis MA, Schroeder JR, Shin AS, Jones HE. Neonatal abstinence syndrome in methadone-exposed infants is altered by level of prenatal tobacco exposure. Drug Alcohol Dependence 2004; 75: 253-260. (Pubitemid 38993295)
7. Demeri O, Celik IM, Sur E, Ozkan Y, Aydin MF, Salbacak A. Histological and morphometric studies of the cerebellar cortex and nucleolus organizer region (Ag-Nors) in Purkinje neurons of chronic morphine treated rats. In: Proceedings of the XVII Intern. Symposium on Morphological Science. Timisoara, Romania, September 2002; 11-15.
8. Dinda A, Gitman M, Singhal PC. Immunomodulatory effect of morphine: therapeutic implications. Expert Opin Drug Saf 2005; 4: 669-675. (Pubitemid 40946065)
9. Farber NB, Onley JW. Drugs of abuse that cause developing neurons to commit suicide. Dev Brain Res 2003; 147: 37-45. (Pubitemid 38114695)
10. Fazel A, Jalali M. Morphine experimentally induced exencephaly and spina bifida in mice. Arch Iranian Med 2002; 5: 179-183. (Pubitemid 35314991)
11. Garcia MM, Gilster J, Harlan RE. Chronic morphine decreases calbindin D-28k immunoreactivity in a subset of cerebellar Purkinje neurons of rat brain. Brain Res 1996; 734: 123-134. (Pubitemid 26334039)
12. Goldstein A. Binding selectivity profiles for ligands of multiple receptor types: focus on opioid receptors. Trends in Pharmacological Sciences 1987; 8: 456-459. (Pubitemid 18001767)
13. Hammer RPJ, Ricalde AA, Seatriz JV. Effects of opiates on brain development. Neurotoxicology 1989; 10: 475-483.
14. Hauser KF, Gurwell JA, Turbek CS. Morphine inhibits Purkinje cell survival and dendritic differentiation in organotypic cultures of the mouse cerebellum. Exp Neurol 1994; 130: 95-105.
15. Hauser KF, Harris-White ME, Jackson JA, Opanashuk LA, Carney JM. Opioids disrupt Ca2+ homeostasis and induce carbonyl oxyradical production in mouse astrocytes in vitro: transient increases and adaptation to sustained exposure. Exp Neurol 1998; 151: 70-76. (Pubitemid 28223856)
16. Hauser KF, Houdi AA, Turbeck CS, Elde RP, Maxson W. Opioids intrinsically inhibit the genesis of mouse cerebellar granule neuron precursors in vitro: differential impact of mu and delta receptor activation on proliferation and neurite elongation. Eur J Neurosci 2000; 12: 1281-1293. (Pubitemid 30224232)
17. Hauser KF. Morphine regulates DNA synthesis in rat cerebellar neuroblasts in vitro. J Dev Brain Res 1992; 70: 291-297. (Pubitemid 23003779)
18. Hauser KF, McLaughlin PJ, Zagon IS. Endogenous opioids regulate dendritic growth and spine formation in developing rat brain. Brain Res 1987; 416: 157-161. (Pubitemid 17102260)
19. Hauser KF, Osborne JG, Stiene-Martin A, Melner MH. Cellular localization of proenkephalin mRNA and enkephalinpeptide products in cultured astrocytes. Brain Res 1990; 522: 347-353. (Pubitemid 20259791)
20. Jacob JT. Effect of the cardiac glycoside digoxin, on neuronal viability, serotonin production and brain development in the embryo. MSc. Thesis in anatomy with specialization in cell biology. School of Medicin, Faculty of Health Science, University of Pretoria, South Africa. 2007.
21. Lorber BA, Freitag SK, Bartolome JV. Effects of beta-endorphin on DNA synthesis in brain regions of preweanling rats. Brain Res 1990; 531: 329-332. (Pubitemid 20348643)
22. Mao J, Sung B, Ji RR, Lim G. Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. J Neurosci 2002; 22: 7650-7661. (Pubitemid 35386364)
23. Nasiraei-Moghadam S, Sahraei H, Bahadoran H, Sadooghi M, Salimi SH, Kaka GR, Imani H, Mahdavi-Nasab H, Dashtnavard H. Effects of maternal oral morphine consumption on neural tube development in Wistar rats. Brain Res Dev Brain Res 2005; 159: 12-17. (Pubitemid 41557709)
24. National Institute on Drug Abuse. National Pregnancy and Health Survey: Drug Use Among Women Delivering Live Births: 1992 (NIH Publication 96-3819). Department of Health and Human Services, Rockville 1996; 1-157.
25. Nestler EJ. Historical review: molecular and cellular mechanisms of opiate and cocaine addiction. Trends Pharmacol Sci 2004; 25: 210-218. (Pubitemid 38519912)
26. Oehmichen M, Meissner C, Reiter A, Birkholz M. Neuropathology in non-human immunodeficiency virus-infected drug addicts: hypoxic brain damage after chronic intravenous drug abuse. Acta Neuropathol 1996; 91: 642-646. (Pubitemid 26166679)
27. Ornoy A, Michailevskaya V, Lukooshov I. The developmental outcome of children born to heroin-dependent mothers, raised at home or adopted. Child Abuse Negl 1996; 20: 385-396. (Pubitemid 26138636)
28. Pretorius E, Bornman MS. Calcium-mediated aponecrosis plays a central role in the pathogenesis of estrogenic chemical-induced neurotoxicity. Med Hypotheses 2005; 65: 893-904.
29. Raehal KM, Bohn LM. Mu opioid receptor regulation and opiate responsiveness. AAPSJ 2005; 7: E587-591.
30. Ray JR, Dubinj W, Blechner JN. Fetal growth retardation following maternal morphine administration: nutritional or drug effect? Biol Neonal 1977; 32: 222-228. (Pubitemid 8265785)
31. Sacerdote P. Opioids and the immune system. Palliat Med 2006; 20: 9-15.
32. Sadraie SH, Kaka GR, Sahraei H. Effects of maternal oral administration of morphine sulfate on developing rat fetal cerebrum: a morphometrical evaluation. Brain Res 2008; 1245: 36-40.
33. Schmahl W, Funk R, Miaskowski U, Plendl J. Long-lasting effects of naltrexone, an opioid receptor antagonist, on cell proliferation in developing rat forebrain. Brain Res 1989; 486: 297-300. (Pubitemid 19135140)
34. Seatrix JV, Hammer RPJ. Effects of opiate on neuronal development in the rat cerebral cortex. Brain Res Bull 1993; 30: 523-527.
35. Shinoda H, Marini AM, Cosi C, Schwartz JP. Brain region and gene specificity of neuropeptide gene expression in cultured astrocytes. Science 1989; 245: 415-417. (Pubitemid 19203367)
36. Simat M, Parpan F, Fritschy JM. Heterogeneity of glycinergic and gabaergic interneurons in the granule cell layer of mouse cerebellum. J Comp Neurol 2007; 500: 71-83. (Pubitemid 44904302)
37. Slotkin TA. Perinatal exposure to methadone: how do early biochemical alterations cause neurofunctional disturbances? Prog Brain Res 1988; 73: 265-279.
38. Spruce BA, Curtis R, Wilkin GP, Glover DM. Aneuropeptide precursor in cerebellum: proenkephalin exists in subpopulations of both neurons and astrocytes. EMBO J 1990; 9: 1787-1795.
39. Thomas JD, Goodlett CR, West JR. Alcohol-induced Purkinje cell loss depends on developmental timing of alcohol exposure and correlates with motor performance. Dev Brain Res 1998; 105: 159-166. (Pubitemid 28153424)
40. Turchan-Cholewo J, Liu Y, Gartner S, Reid R, Jie C, Peng X. Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl. Neurobiol Dis 2006; 23: 109-119. (Pubitemid 43922460)
41. Wilson GS, McCreay R, Kean J, Baxter JC. The development of pre-school children of heroin-addicted mothers: a controlled study. Pediatrics 1979; 63: 135-141. (Pubitemid 9111213)
42. Zagon IS, McLaughlin PJ. Endogenous opioids regulate cell proliferation in the developing rat brain. Brain Res 1987; 412: 68-72. (Pubitemid 17096684)
43. Zagon IS, McLaughlin PJ. Identification of opioid peptides regulating proliferation of neurons and glia in the developing nervous system. Brain Res 1991; 542: 318-323.
44. Zhang Y, Chen Q, Yu LC. Morphine: a protective or destructive role in neurons? Neuroscientist 2008; 14: 561-570.
45. Zhu Y, Hsu MS, Pintar JE. Developmental expression of the mu, kappa and delta opioid receptor mRNAs in mouse. J Neurosci 1998; 18: 2538-2549. (Pubitemid 28141801)