Physicochemical properties and oral bioavailability of ursolic acid nanoparticles using supercritical anti-solvent (SAS) process

Food Chemistry

Volumn 132, Issue 1, 2012, Pages 319-325

  Yang, Lei ^a   Sun, Zhen ^a   Zu, Yuangang ^a   Zhao, Chunjian ^a   Sun, Xiaowei ^a   Zhang, Zhonghua ^a   Zhang, Lin ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

Author keywords

Bioavailability; Nanoparticles; Supercritical anti solvent process; Ursolic acid

Indexed keywords

GRAVIMETRIC ANALYSIS; INFRARED SPECTROSCOPY; NANOPARTICLES; SCANNING ELECTRON MICROSCOPY; SOLVENTS; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION; X RAY DIFFRACTION ANALYSIS;

AMORPHOUS STATE; ANTI-SOLVENTS; BIOAVAILABILITY; DISSOLUTION TESTS; DRUG CONCENTRATION; DRUG SOLUTIONS; MEAN PARTICLE SIZE; PARTICLE FORMATIONS; PARTICLE SIZE REDUCTION; PHYSICAL MODIFICATIONS; PHYSICOCHEMICAL PROPERTY; PROCESS PARAMETERS; PROCESS VARIABLES; SUPER-CRITICAL; THERMAL GRAVIMETRIC ANALYSIS; URSOLIC ACID;

BIOCHEMISTRY;

NANOPARTICLE; URSOLIC ACID; SOLVENT; TRITERPENE;

ANIMAL EXPERIMENT; ARTICLE; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG SOLUTION; FLOW RATE; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRESSURE; PROCESSING; RAT; SCANNING ELECTRON MICROSCOPY; SUPERCRITICAL ANTISOLVENT PROCESS; TEMPERATURE; THERMOGRAVIMETRY; X RAY DIFFRACTION; BIOAVAILABILITY; CHEMISTRY; ORAL DRUG ADMINISTRATION;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; NANOPARTICLES; PHYSICOCHEMICAL PROCESSES; SOLVENTS; TRITERPENES;

EID: 84355166537     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.10.083     Document Type: Article

References (34)

1. S. Balanehru, and B. Nagarajan Protective effect of oleanolic acid and ursolic acid against lipid peroxidation Biochemistry International 24 1991 981 990
2. S. Binduja, P.K.S. Visen, and D.P. Agarwal Ursolic acid isolated from Eucalyptus tereticornis protects against ethanol toxicity in isolated rat hepatocytes Phytotherapy Research 14 2000 163 166 (Pubitemid 30326008)
3. I. Brigger, C. Dubernet, and P. Couvreur Nanoparticles in cancer therapy and diagnosis Advanced Drug Delivery Reviews 54 2002 631 651 (Pubitemid 35247520)
4. M.A.T. Cardoso, G.A. Monteiro, J.P. Cardoso, T.J.V. Prazeres, J.M.F. Figueiredo, J.M.G. Martinho, J.M.S. Cabral, and A.M.F. Palavra Supercritical antisolvent micronisation of minocycline hydrochloride The Journal of Supercritical Fluids 44 2008 238 244
5. 2 antisolvent with enhanced mass transfer International Journal of Pharmaceutics 228 2001 19 31 (Pubitemid 32905362)
6. H. Gwak, J. Choi, and H. Choi Enhanced bioavailability of piroxicam via salt formation with ethanolamines International Journal of Pharmaceutics 297 2005 156 161 (Pubitemid 40720275)
7. Y. Hakuta, H. Hayashi, and K. Arai Fine particle formation using supercritical fluids, current opinion in solid state Materials Science 7 2003 341 351 (Pubitemid 38462041)
8. P.O. Harmand, R. Duval, C. Delage, and A. Simon Ursolic acid induces apoptosis through mitochondrial intrinsic pathway and caspase-3 activation in M4Beu melanoma cells International Journal of Cancer 114 2005 1 11 (Pubitemid 40194303)
9. H.L. Hong, Q.L. Suo, L.M. Han, and C.P. Li Study on precipitation of astaxanthin in supercritical fluid Powder Technology 191 2009 294 298
10. J. Jung, and M. Perrut Particle design using supercritical fluids: Literature and patent survey The Journal of Supercritical Fluids 20 2001 179 219 (Pubitemid 32607129)
11. C.G. Kalogiannis, E. Pavlidou, and C.G. Panayiotou Production of amoxicillin microparticles by supercritical antisolvent precipitation Industrial & Engineering Chemistry Research 44 2005 9339 9346 (Pubitemid 41801578)
12. M. Kim, S. Jin, J. Kim, H. Park, H. Song, R. Neubert, and S. Hwang Preparation, characterisation and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process European journal of pharmaceutics and biopharmaceutics 69 2008 454 465
13. Q.F. Liao, W. Yang, Y. Jia, X.H. Chen, Q.T. Gao, and K.S. Bi LC-MS determination and pharmacokinetic studies of ursolic acid in rat plasma after administration of the traditional Chinese medicinal preparation Lu-Ying extract The Pharmaceutical Society of Japan 125 2005 509 515 (Pubitemid 40874445)
14. J. Liu Pharmacology of oleanolic acid and ursolic acid Journal of Ethnopharmacology 49 1995 57 68 (Pubitemid 26010740)
15. J. Lu, Y.L. Zheng, D.M. Wu, L. Luo, D.X. Sun, and Q. Shan Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose Biochemical Pharmacology 74 2007 1078 1090 (Pubitemid 47284011)
16. I.D. Marco, and E. Reverchon Influence of pressure, temperature and concentration on the mechanisms of particle precipitation in supercritical antisolvent micronisation The Journal of Supercritical Fluids 58 2011 295 302
17. Z. Ovesná, K. Kozics, and D. Slameňová Protective effects of ursolic acid and oleanolic acid in leukemic cells Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 600 2006 131 137
18. C.I. Park, M.S. Shin, and H.Y. Kim Micronisation of arbutine using supercritical anti-solvent Korean Journal of Chemical Engineering 25 2008 581 584
19. I. Pasquali, R. Bettini, and F. Giordano Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics European Journal of Pharmaceutical Sciences 27 2006 299 310 (Pubitemid 43148948)
20. P. Pathak, M.J. Meziani, T. Desai, and Y.P. Sun Nanosizing drug particles in supercritical fluid processing Journal of the American Chemical Society 126 2004 10842 10843 (Pubitemid 39180560)
21. V. Patravale, A. Date, and R. Kulkarni Nanosuspensions: A promising drug delivery strategy Journal of Pharmacy and Pharmacology 56 2004 827 840 (Pubitemid 38885975)
22. B. Prabagar, B. Yoo, J. J Woo, J. Kim, J. Rhee, M.G. Piao, H. Choi, and C.S. Yong Enhanced bioavailability of poorly water-soluble clotrimazole by inclusion with β-cyclodextrin Archives of Pharmacal Research 30 2007 249 254
23. K.R. Price, I.T. Johnson, G. Fenwick, and M. Malinow The chemistry and biological significance of saponins in foods and feeding stuffs Critical Reviews in Food Science and Nutrition 26 1987 27 135
24. E. Reverchon Supercritical antisolvent precipitation of micro-and nano-particles The Journal of Supercritical Fluids 15 1999 1 21 (Pubitemid 129671809)
25. E. Reverchon, I.D. Marco, and G.D. Porta Rifampicin microparticles production by supercritical antisolvent precipitation International Journal of Pharmaceutics 243 2002 83 91
26. R. Saravanan, P. Viswanathan, and K.V. Pugalendi Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats Life Sciences 78 2006 713 718 (Pubitemid 41821127)
27. G.V. Shavi, A.R. Kumar, Y.N. Usha, K. Armugam, O. Ranjan, K. Ginjupalli, S. Pandey, and N. Udupa Enhanced dissolution and bioavailability of gliclazide using solid dispersion techniques International Journal of Drug Delivery 2 2010 49 57
28. Y.H. Shih, Y.C. Chein, J.Y. Wang, and Y.S. Fu Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats Neuroscience Letters 362 2004 136 140
29. L.O. Somova, A. Nadar, P. Rammanan, and F.O. Shode Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension Phytomedicine 10 2003 115 121 (Pubitemid 36433204)
30. D.H. Won, M.S. Kim, S. Lee, J.S. Park, and S.J. Hwang Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process International Journal of Pharmaceutics 301 2005 199 208 (Pubitemid 41206604)
31. L. Yang, J.M. Huang, Y.G. Zu, C.H. Ma, H. Wang, X.W. Sun, and Z. Sun Preparation and radical scavenging activities of polymeric procyanidins nanoparticles by a supercritical antisolvent (SAS) process Food Chemistry 128 2011 1152 1159
32. Y. Yin, F. Cui, C. Mu, M. Choi, J.S. Kim, S. Chung, C. Shim, and D. Kim Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation Journal of Controlled Release 140 2009 86 94
33. C. Zhao, L. Wang, Y. Zu, C. Li, S. Liu, L. Yang, X. Zhao, and B. Zu Micronisation of Ginkgo biloba extract using supercritical antisolvent process Powder Technology 209 2011 73 80
34. X. Zhao, Y. Zu, Q. Li, M. Wang, B. Zu, X. Zhang, R. Jiang, and C. Zu Preparation and characterisation of camptothecin powder micronized by a supercritical antisolvent (SAS) process The Journal of Supercritical Fluids 12 2010 412 419