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Volumn 9, Issue 1, 2012, Pages 91-103

Iontophoretic drug delivery across the nail

Author keywords

Iontophoresis; Nail; Onychomycosis; Terbinafine; Topical

Indexed keywords

AMOROLFINE; CICLOPIROX; CICLOPIROXOLAMINE; FLUCONAZOLE; ITRACONAZOLE; TERBINAFINE; TIOCONAZOLE; TRIAMCINOLONE ACETONIDE;

EID: 84255171218     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2012.642364     Document Type: Review
Times cited : (33)

References (94)
  • 2
    • 77956621286 scopus 로고    scopus 로고
    • Toenail onychomycosis: An important global disease burden
    • Thomas J, Jacobson GA, Narkowicz CK, et al. Toenail onychomycosis: an important global disease burden. J Clin Pharm Ther 2010;35:497-519
    • (2010) J Clin Pharm Ther , vol.35 , pp. 497-519
    • Thomas, J.1    Jacobson, G.A.2    Narkowicz, C.K.3
  • 3
    • 72049102873 scopus 로고    scopus 로고
    • Nail psoriasis: Clinical presentation and best practice recommendations
    • Edwards F, de Berker D. Nail psoriasis: clinical presentation and best practice recommendations. Drugs 2009;69:2351-61
    • (2009) Drugs , vol.69 , pp. 2351-61
    • Edwards, F.1    De Berker, D.2
  • 5
    • 63049083901 scopus 로고    scopus 로고
    • Management of psoriatic nail disease
    • de Berker D. Management of psoriatic nail disease. Semin Cutan Med Surg 2009;28:39-43
    • (2009) Semin Cutan Med Surg , vol.28 , pp. 39-43
    • De Berker, D.1
  • 6
    • 0033778442 scopus 로고    scopus 로고
    • Management of nail psoriasis
    • de Berker D. Management of nail psoriasis. Clin Exp Dermatol 2000;25:357-62
    • (2000) Clin Exp Dermatol , vol.25 , pp. 357-62
    • De Berker, D.1
  • 7
    • 84921431339 scopus 로고    scopus 로고
    • Topical treatments for fungal infections of the skin and nails of the foot
    • Crawford F, Hart R, Bell-Syer S, et al. Topical treatments for fungal infections of the skin and nails of the foot. Cochrane Database Syst Rev 2000(1):CD001434
    • (2000) Cochrane Database Syst Rev , Issue.1
    • Crawford, F.1    Hart, R.2    Bell-Syer, S.3
  • 9
    • 57049140007 scopus 로고    scopus 로고
    • Enhancing the nail permeability of topically applied drugs
    • Murdan S. Enhancing the nail permeability of topically applied drugs. Expert Opin Drug Del 2008;5:1267-82
    • (2008) Expert Opin Drug Del , vol.5 , pp. 1267-82
    • Murdan, S.1
  • 10
    • 84255165633 scopus 로고    scopus 로고
    • Nail delivery
    • Rathbone MJ, Hadgraft J, Roberts MS, Lane ME, editors 2nd edition. Informa Healthcare; New York
    • Green DM, Brain KR, Walters KA. Nail Delivery. In: Rathbone MJ, Hadgraft J, Roberts MS, Lane ME, editors. Modified-release drug delivery technology. Volume 2 2nd edition. Informa Healthcare; New York: 2008. p. 383-93
    • (2008) Modified-release Drug Delivery Technology , vol.2 , pp. 383-93
    • Green, D.M.1    Brain, K.R.2    Walters, K.A.3
  • 11
    • 70649115369 scopus 로고    scopus 로고
    • Transungual drug delivery: Current status
    • Elkeeb R, AliKhan A, Elkeeb L, et al. Transungual drug delivery: current status. Int J Pharm Jan 2010;384:1-8
    • (2010) Int J Pharm Jan , vol.384 , pp. 1-8
    • Elkeeb, R.1    Alikhan, A.2    Elkeeb, L.3
  • 12
    • 3142547033 scopus 로고    scopus 로고
    • Reverse iontophoresis for non-invasive transdermal monitoring
    • DOI 10.1088/0967-3334/25/3/R01, PII S0967333404542739
    • Leboulanger B, Guy RH, Delgado-Charro MB. Reverse iontophoresis for non-invasive transdermal monitoring. Phys Meas 2004;25:R35-50 (Pubitemid 38901997)
    • (2004) Physiological Measurement , vol.25 , Issue.3
    • Leboulanger, B.1    Guy, R.H.2    Delgado-Charro, M.B.3
  • 13
    • 0001385422 scopus 로고
    • Iontophoresis
    • Hadgraft J, Guy RH editors Marcel Dekker; New York
    • Burnette RR. Iontophoresis. In: Hadgraft J, Guy RH, editors. Transdermal drug delivery. Marcel Dekker; New York: 1989
    • (1989) Transdermal Drug Delivery
    • Burnette, R.R.1
  • 15
    • 63649107817 scopus 로고    scopus 로고
    • Recent advances on transdermal iontophoretic drug delivery and non-invasive sampling
    • Delgado-Charro MB. Recent advances on transdermal iontophoretic drug delivery and non-invasive sampling. J Drug Deliv Sci Tec 2009;19:75-88
    • (2009) J Drug Deliv Sci Tec , vol.19 , pp. 75-88
    • Delgado-Charro, M.B.1
  • 16
    • 4043173348 scopus 로고    scopus 로고
    • Iontophoresis: Applications in drug delivery and non-invasive monitoring
    • Guy RH Hadgraft J editors 2nd edition. Marcel Dekker, New York
    • Delgado-Charro MB, Guy RH. Iontophoresis: Applications in drug delivery and non-invasive monitoring. In: Guy RH, Hadgraft J, editors, Transdermal drug delivery. 2nd edition. Marcel Dekker, New York; 2003
    • (2003) Transdermal Drug Delivery
    • Delgado-Charro, M.B.1    Guy, R.H.2
  • 17
    • 31544465937 scopus 로고    scopus 로고
    • Iontophoresis: A non-invasive ocular drug delivery
    • DOI 10.1016/j.jconrel.2005.09.049, PII S0168365905005286
    • Eljarrat-Binstock E, Domb AJ. Iontophoresis: a non-invasive ocular drug delivery. J Control Release 2006;110:479-89 (Pubitemid 43163439)
    • (2006) Journal of Controlled Release , vol.110 , Issue.3 , pp. 479-489
    • Eljarrat-Binstock, E.1    Domb, A.J.2
  • 18
    • 0026651040 scopus 로고
    • Model systems in iontophoresis-transport efficacy
    • Sage BH, Riviere JE. Model systems in iontophoresis-transport efficacy. Adv Drug Deliver Rev 1992;9:265-87
    • (1992) Adv Drug Deliver Rev , vol.9 , pp. 265-87
    • Sage, B.H.1    Riviere, J.E.2
  • 20
    • 0026928482 scopus 로고
    • The role of electroosmotic flow in transdermal iontophoresis
    • Pikal MJ. The role of electroosmotic flow in transdermal iontophoresis Adv Drug Deliver Rev. 1992;9:201-37
    • (1992) Adv Drug Deliver Rev. , vol.9 , pp. 201-37
    • Pikal, M.J.1
  • 21
    • 0026924780 scopus 로고
    • Skin biological issues in electrically enhanced transdermal delivery
    • Ledger PW. Skin biological issues in electrically enhanced transdermal delivery. Adv Drug Deliver Rev 1992;9:289-307
    • (1992) Adv Drug Deliver Rev , vol.9 , pp. 289-307
    • Ledger, P.W.1
  • 22
    • 0024565708 scopus 로고
    • Application of electrodiffusion theory for a homogeneous membrane to iontophoretic transport through skin
    • DOI 10.1016/0168-3659(89)90042-4
    • Kasting GB, Keister JC. Application of electrodiffusion theory for a homogeneous membrane to iontophoretic transport through skin. J Control Release 1989;8:195-210 (Pubitemid 19098999)
    • (1989) Journal of Controlled Release , vol.8 , Issue.3 , pp. 195-210
    • Kasting, G.B.1    Keister, J.C.2
  • 23
    • 0035659460 scopus 로고    scopus 로고
    • Contributions of electromigration and electroosmosis to iontophoretic drug delivery
    • DOI 10.1023/A:1013318412527
    • Marro D, Kalia YN, Delgado-Charro MB, et al. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Pharm Res 2001;18:1701-8 (Pubitemid 34020425)
    • (2001) Pharmaceutical Research , vol.18 , Issue.12 , pp. 1701-1708
    • Marro, D.1    Kalia, Y.N.2    Delgado-Charro, M.B.3    Guy, R.H.4
  • 24
    • 34548386588 scopus 로고    scopus 로고
    • Quantitative structure-permeation relationship for iontophoretic transport across the skin
    • DOI 10.1016/j.jconrel.2007.07.004, PII S0168365907003604
    • Mudry B, Carrupt PA, Guy RH, et al. Quantitative structure-permeation relationship for iontophoretic transport across the skin. J Control Release 2007;122:165-72 (Pubitemid 47361407)
    • (2007) Journal of Controlled Release , vol.122 , Issue.2 , pp. 165-172
    • Mudry, B.1    Carrupt, P.-A.2    Guy, R.H.3    Delgado-Charro, M.B.4
  • 26
    • 33645225108 scopus 로고    scopus 로고
    • Transport numbers in transdermal iontophoresis
    • Mudry B, Guy RH, Delgado-Charro MB. Transport numbers in transdermal iontophoresis. Biophys J 2006;90:2822-30
    • (2006) Biophys J , vol.90 , pp. 2822-30
    • Mudry, B.1    Guy, R.H.2    Delgado-Charro, M.B.3
  • 27
    • 33645339785 scopus 로고    scopus 로고
    • Electromigration of ions across the skin: Determination and prediction of transport numbers
    • Mudry B, Guy RH, Delgado-Charro MB. Electromigration of ions across the skin: determination and prediction of transport numbers. J Pharm Sci 2006;95:561-9
    • (2006) J Pharm Sci , vol.95 , pp. 561-9
    • Mudry, B.1    Guy, R.H.2    Delgado-Charro, M.B.3
  • 28
    • 77957019192 scopus 로고    scopus 로고
    • Trans-scleral iontophoretic delivery of low molecular weight therapeutics
    • Gungor S, Delgado-Charro MB, Ruiz-Perez B, et al. Trans-scleral iontophoretic delivery of low molecular weight therapeutics. J Control Release 2010;147:225-31
    • (2010) J Control Release , vol.147 , pp. 225-31
    • Gungor, S.1    Delgado-Charro, M.B.2    Ruiz-Perez, B.3
  • 30
    • 0035966545 scopus 로고    scopus 로고
    • Characterization of the iontophoretic permselectivity properties of human and pig skin
    • DOI 10.1016/S0168-3659(00)00350-3, PII S0168365900003503
    • Marro D, Guy RH, Delgado-Charro MB. Characterization of the iontophoretic permselectivity properties of human and pig skin. J Control Release 2001;70:213-17 (Pubitemid 32144805)
    • (2001) Journal of Controlled Release , vol.70 , Issue.1-2 , pp. 213-217
    • Marro, D.1    Guy, R.H.2    Delgado-Charro, M.B.3
  • 31
    • 0025325427 scopus 로고
    • Transport mechanisms in iontophoresis. I. A theoretical model for the effect of electroosmotic flow on flux enhancement in transdermal iontophoresis
    • DOI 10.1023/A:1015816532532
    • Pikal MJ. Transport mechanisms in iontophoresis. I. A theoretical model for the effect of electroosmotic flow on flux enhancement in transdermal iontophoresis. Pharm Res 1990;7:118-26 (Pubitemid 20208062)
    • (1990) Pharmaceutical Research , vol.7 , Issue.2 , pp. 118-126
    • Pikal, M.J.1
  • 32
    • 0023426505 scopus 로고
    • Characterization of the permselective properties of excised human skin during iontophoresis
    • Burnette RR, Ongpipattanakul B. Characterization of the permselective properties of excised human skin during iontophoresis. J Pharm Sci 1987;76:765-73
    • (1987) J Pharm Sci , vol.76 , pp. 765-73
    • Burnette, R.R.1    Ongpipattanakul, B.2
  • 33
    • 0030272432 scopus 로고    scopus 로고
    • Reverse iontophoresis: Parameters determining electro-osmotic flow. II. Electrode chamber formulation
    • DOI 10.1016/0168-3659(96)01345-4
    • Santi P, Guy RH. Reverse iontophoresis - parameters determining electro-osmotic flow. 2.Electrode chamber formulation. J Control Release 1996;42:29-36 (Pubitemid 26297873)
    • (1996) Journal of Controlled Release , vol.42 , Issue.1 , pp. 29-36
    • Santi, P.1    Guy, R.H.2
  • 34
    • 0029919084 scopus 로고    scopus 로고
    • Reverse iontophoresis - Parameters determining electroosmotic flow: I. pH and ionic strength
    • DOI 10.1016/0168-3659(95)00115-8
    • Santi P, Guy RH. Reverse iontophoresis - Parameters determining electroosmotic flow.1. pH and ionic strength. J Control Release 1996;38:159-65 (Pubitemid 26096660)
    • (1996) Journal of Controlled Release , vol.38 , Issue.2-3 , pp. 159-165
    • Santi, P.1    Guy, R.H.2
  • 36
    • 0022643278 scopus 로고
    • Percutaneous iontophoresis of prednisolone - A pharmacokinetic study
    • DOI 10.1111/j.1365-2230.1986.tb00424.x
    • James MP, Graham RM, English J. Percutaneous iontophoresis of prednisolone-a pharmacokinetic study. Clin Exp Dermatol 1986;11:54-61 (Pubitemid 16201375)
    • (1986) Clinical and Experimental Dermatology , vol.11 , Issue.1 , pp. 54-61
    • James, M.P.1    Graham, R.M.2    English, J.3
  • 39
    • 39749153039 scopus 로고    scopus 로고
    • Transungual iontophoretic transport of polar neutral and positively charged model permeants: Effects of electrophoresis and electroosmosis
    • DOI 10.1002/jps.21025
    • Hao JS, Li SK. Transungual iontophoretic transport of polar neutral and positively charged model permeants: Effects of electrophoresis and electroosmosis. J Pharm Sci 2008;97:893-905 (Pubitemid 351293889)
    • (2008) Journal of Pharmaceutical Sciences , vol.97 , Issue.2 , pp. 893-905
    • Hao, J.1    Li, S.K.2
  • 40
    • 77953594289 scopus 로고    scopus 로고
    • Electroosmotic transport of mannitol across human nail during constant current iontophoresis
    • Dutet J, Delgado-Charro MB. Electroosmotic transport of mannitol across human nail during constant current iontophoresis. J Pharm Pharmacol 2010;62:721-9
    • (2010) J Pharm Pharmacol , vol.62 , pp. 721-9
    • Dutet, J.1    Delgado-Charro, M.B.2
  • 41
    • 77952670322 scopus 로고    scopus 로고
    • Transungual iontophoresis of lithium and sodium: Effect of pH and co-ion competition on cationic transport numbers
    • Dutet J, Delgado-Charro MB. Transungual iontophoresis of lithium and sodium: effect of pH and co-ion competition on cationic transport numbers. J Control Release 2010;144:168-74
    • (2010) J Control Release , vol.144 , pp. 168-74
    • Dutet, J.1    Delgado-Charro, M.B.2
  • 42
    • 0019348871 scopus 로고
    • The human nail: Structure, growth and pathological changes
    • Runne U, Orfanos CE. The human nail: structure, growth and pathological changes. Curr Probl Dermatol 1981;9:102-49
    • (1981) Curr Probl Dermatol , vol.9 , pp. 102-49
    • Runne, U.1    Orfanos, C.E.2
  • 43
    • 57049159644 scopus 로고    scopus 로고
    • Mechanistic study of electroosmotic transport across hydrated nail plates: Effects of pH and ionic strength
    • Hao J, Li SK. Mechanistic study of electroosmotic transport across hydrated nail plates: effects of pH and ionic strength. J Pharm Sci 2008;97:5186-97
    • (2008) J Pharm Sci , vol.97 , pp. 5186-97
    • Hao, J.1    Li, S.K.2
  • 44
    • 42749095174 scopus 로고    scopus 로고
    • Chemical method to enhance transungual transport and iontophoresis efficiency
    • Hao JS, Smith KA, Li SK. Chemical method to enhance transungual transport and iontophoresis efficiency. Int J Pharm 2008;357:61-9
    • (2008) Int J Pharm , vol.357 , pp. 61-9
    • Hao, J.S.1    Smith, K.A.2    Li, S.K.3
  • 45
    • 67349193547 scopus 로고    scopus 로고
    • Effects of ionic strength on passive and iontophoretic transport of cationic permeant across human nail
    • Smith KA, Hao J, Li SK. Effects of ionic strength on passive and iontophoretic transport of cationic permeant across human nail. Pharm Res 2009;26:1446-55
    • (2009) Pharm Res , vol.26 , pp. 1446-55
    • Smith, K.A.1    Hao, J.2    Li, S.K.3
  • 46
    • 73949125681 scopus 로고    scopus 로고
    • Time-dependent electrical properties of human nail upon hydration in vivo
    • Hao J, Smith KA, Li SK. Time-dependent electrical properties of human nail upon hydration in vivo. J Pharm Sci 2010;99:107-18
    • (2010) J Pharm Sci , vol.99 , pp. 107-18
    • Hao, J.1    Smith, K.A.2    Li, S.K.3
  • 47
    • 67349218515 scopus 로고    scopus 로고
    • Iontophoretically enhanced ciclopirox delivery into and across human nail plate
    • Hao J, Smith KA, Li SK. Iontophoretically enhanced ciclopirox delivery into and across human nail plate. J Pharm Sci 2009;98:3608-16
    • (2009) J Pharm Sci , vol.98 , pp. 3608-16
    • Hao, J.1    Smith, K.A.2    Li, S.K.3
  • 48
    • 65949087874 scopus 로고    scopus 로고
    • Trans-ungual iontophoretic delivery of terbinafine
    • Nair AB, Vaka SR, Sammeta SM, et al. Trans-ungual iontophoretic delivery of terbinafine. J Pharm Sci 2009;98:1788-96
    • (2009) J Pharm Sci , vol.98 , pp. 1788-96
    • Nair, A.B.1    Vaka, S.R.2    Sammeta, S.M.3
  • 49
    • 80052456636 scopus 로고    scopus 로고
    • Transungual delivery of terbinafine by iontophoresis in onychomycotic nails
    • published online 4 April 2011; doi:10.3109/03639045.2011.568946
    • Nair AB, Kiran Vaka SR, Murthy SN. Transungual delivery of terbinafine by iontophoresis in onychomycotic nails. Drug Dev Ind Pharmacy 2011 published online 4 April 2011; doi:10.3109/03639045.2011.568946
    • (2011) Drug Dev Ind Pharmacy
    • Nair, A.B.1    Kiran Vaka, S.R.2    Murthy, S.N.3
  • 50
    • 68149161625 scopus 로고    scopus 로고
    • An ex vivo toe model used to assess applicators for the iontophoretic ungual delivery of terbinafine
    • Nair AB, Kim HD, Davis SP, et al. An ex vivo toe model used to assess applicators for the iontophoretic ungual delivery of terbinafine. Pharm Res 2009;26:2194-201
    • (2009) Pharm Res , vol.26 , pp. 2194-201
    • Nair, A.B.1    Kim, H.D.2    Davis, S.P.3
  • 51
    • 77952669400 scopus 로고    scopus 로고
    • Iontophoretic terbinafine HCL 1.0% delivery across porcine and human nails
    • Amichai B, Mosckovitz R, Trau H, et al. Iontophoretic terbinafine HCL 1.0% delivery across porcine and human nails. Mycopathologia 2010;169:343-9
    • (2010) Mycopathologia , vol.169 , pp. 343-9
    • Amichai, B.1    Mosckovitz, R.2    Trau, H.3
  • 52
    • 84255208577 scopus 로고    scopus 로고
    • Iontophoresis to enhance topical delivery of terbinafine to the nail
    • Ramaswamy C, Kim H, Fridam P, et al. Iontophoresis to enhance topical delivery of terbinafine to the nail. Skin Forum 8th Annual Meeting, 2007, p.24
    • (2007) Skin Forum 8th Annual Meeting , pp. 24
    • Ramaswamy, C.1    Kim, H.2    Fridam, P.3
  • 53
    • 79955039597 scopus 로고    scopus 로고
    • Effect of polyethylene glycols on the trans-ungual delivery of terbinafine
    • Nair AB, Chakraborty B, Murthy SN. Effect of polyethylene glycols on the trans-ungual delivery of terbinafine. Curr Drug Delivery 2010;7:407-14
    • (2010) Curr Drug Delivery , vol.7 , pp. 407-14
    • Nair, A.B.1    Chakraborty, B.2    Murthy, S.N.3
  • 54
    • 67349211775 scopus 로고    scopus 로고
    • Alteration of the diffusional barrier property of the nail leads to greater terbinafine drug loading and permeation
    • Nair AB, Sammeta SM, Kim HD, et al. Alteration of the diffusional barrier property of the nail leads to greater terbinafine drug loading and permeation. Int J Pharm 2009;375:22-7
    • (2009) Int J Pharm , vol.375 , pp. 22-7
    • Nair, A.B.1    Sammeta, S.M.2    Kim, H.D.3
  • 55
    • 68149168360 scopus 로고    scopus 로고
    • Ungual and trans-ungual iontophoretic delivery of terbinafine for the treatment of onychomycosis
    • Nair AB, Kim HD, Chakraborty B, et al. Ungual and trans-ungual iontophoretic delivery of terbinafine for the treatment of onychomycosis. J Pharm Sci 2009;98:4130-40
    • (2009) J Pharm Sci , vol.98 , pp. 4130-40
    • Nair, A.B.1    Kim, H.D.2    Chakraborty, B.3
  • 56
    • 52949122473 scopus 로고    scopus 로고
    • A few aspects of transonychial water loss (TOWL): Inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish
    • Murdan S, Hinsu D, Guimier M. A few aspects of transonychial water loss (TOWL): inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish. Eur J Pharm Biopharm 2008;70:684-9
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 684-9
    • Murdan, S.1    Hinsu, D.2    Guimier, M.3
  • 57
    • 77949831375 scopus 로고    scopus 로고
    • Influence of pH on transungual passive and iontophoretic transport
    • Smith KA, Hao J, Li SK. Influence of pH on transungual passive and iontophoretic transport. J Pharm Sci 2010;99:1955-67
    • (2010) J Pharm Sci , vol.99 , pp. 1955-67
    • Smith, K.A.1    Hao, J.2    Li, S.K.3
  • 58
    • 72749103231 scopus 로고    scopus 로고
    • Iontophoretic delivery of terbinafine in onychomycosis: A preliminary study
    • Amichai B, Nitzan B, Mosckovitz R, et al. Iontophoretic delivery of terbinafine in onychomycosis: a preliminary study. Br J Dermatol 2010;162:46-50
    • (2010) Br J Dermatol , vol.162 , pp. 46-50
    • Amichai, B.1    Nitzan, B.2    Mosckovitz, R.3
  • 59
    • 70350619628 scopus 로고    scopus 로고
    • In vivo transungual iontophoresis: Effect of DC current application on ionic transport and on transonychial water loss
    • Dutet J, Delgado-Charro MB. In vivo transungual iontophoresis: effect of DC current application on ionic transport and on transonychial water loss. J Control Release 2009;140:117-25
    • (2009) J Control Release , vol.140 , pp. 117-25
    • Dutet, J.1    Delgado-Charro, M.B.2
  • 60
    • 35748948955 scopus 로고    scopus 로고
    • Effect of hydration on the permeation of ketoconazole through human nail plate in vitro
    • DOI 10.1016/j.ejps.2007.07.009, PII S0928098707003247
    • Gunt HB, Kasting GB. Effect of hydration on the permeation of ketoconazole through human nail plate in vitro. Eur J Pharm Sci 2007;32:254-60 (Pubitemid 350051888)
    • (2007) European Journal of Pharmaceutical Sciences , vol.32 , Issue.4-5 , pp. 254-260
    • Gunt, H.B.1    Kasting, G.B.2
  • 61
    • 82755189404 scopus 로고    scopus 로고
    • Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof: Implications for drug delivery
    • doi:10.1016/j.jconrel.2011.08.021
    • Nogueiras Nieto L, Gomez Amoza JL, Delgado Charro MB, et al. Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof: Implications for drug delivery. J Control Release 2011;doi:10.1016/j.jconrel. 2011.08.021
    • (2011) J Control Release
    • Nogueiras Nieto, L.1    Gomez Amoza, J.L.2    Delgado Charro, M.B.3
  • 65
    • 65449149031 scopus 로고    scopus 로고
    • Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia
    • Bragulla HH, Homberger DG. Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat 2009;214:516-59
    • (2009) J Anat , vol.214 , pp. 516-59
    • Bragulla, H.H.1    Homberger, D.G.2
  • 68
    • 0031446133 scopus 로고    scopus 로고
    • Iontophoretic transport pathways: Dependence on penetrant physicochemical properties
    • Turner NG, Guy RH. Iontophoretic transport pathways: dependence on penetrant physicochemical properties. J Pharm Sci 1997;86:1385-9
    • (1997) J Pharm Sci , vol.86 , pp. 1385-9
    • Turner, N.G.1    Guy, R.H.2
  • 69
    • 0033636424 scopus 로고    scopus 로고
    • Scanning electrochemical microscopy of iontophoretic transport in hairless mouse skin. Analysis of the relative contributions of diffusion, migration, and electroosmosis to transport in hair follicles
    • Bath BD, Scott ER, Phipps JB, et al. Scanning electrochemical microscopy of iontophoretic transport in hairless mouse skin. Analysis of the relative contributions of diffusion, migration, and electroosmosis to transport in hair follicles. J Pharm Sci 2000;89:1537-49
    • (2000) J Pharm Sci , vol.89 , pp. 1537-49
    • Bath, B.D.1    Scott, E.R.2    Phipps, J.B.3
  • 70
    • 0028869479 scopus 로고
    • Direct imaging of molecular transport through skin
    • Scott ER, Phipps JB, White HS. Direct imaging of molecular transport through skin. J Invest Dermatol 1995;104:142-5
    • (1995) J Invest Dermatol , vol.104 , pp. 142-5
    • Scott, E.R.1    Phipps, J.B.2    White, H.S.3
  • 71
    • 46249121350 scopus 로고    scopus 로고
    • Use of softening agents to improve the production of formalin-fixed, paraffin-embedded sections of nail tissue: An assessment
    • Orchard GE, Torres J, Sounthararajah R. Use of softening agents to improve the production of formalin-fixed, paraffin-embedded sections of nail tissue: an assessment. Brit J Biomed Sci 2008;65:68-70 (Pubitemid 351913977)
    • (2008) British Journal of Biomedical Science , vol.65 , Issue.2 , pp. 68-70
    • Orchard, G.E.1    Torres, J.2    Sounthararajah, P.3
  • 72
    • 0021723695 scopus 로고
    • Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: Effect on circulating lymphocyte subsets and function
    • Frey BM, Walker C, Frey FJ, et al. Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: effect on circulating lymphocyte subsets and function. J Immunol 1984;133:2479-87 (Pubitemid 15204772)
    • (1984) Journal of Immunology , vol.133 , Issue.5 , pp. 2479-2487
    • Frey, B.M.1    Walker, C.2    Frey, F.J.3    De Weck, A.L.4
  • 73
    • 0023006318 scopus 로고
    • The dose-dependent systemic availability of prednisone: One reason for the reduced biological effect of alternate-day prednisone
    • Frey FJ, Ruegsegger MK, Frey BM. The dose-dependent systemic availability of prednisone: one reason for the reduced biological effect of alternate-day prednisone. Brit J Clin Pharmacol 1986;21:183-9 (Pubitemid 17189978)
    • (1986) British Journal of Clinical Pharmacology , vol.21 , Issue.2 , pp. 183-189
    • Frey, F.J.1    Ruegsegger, M.K.2    Frey, B.M.3
  • 74
    • 34247877773 scopus 로고    scopus 로고
    • Pseudomonas chloronychia in a patient with nail psoriasis
    • Sakata S, Howard A. Pseudomonas chloronychia in a patient with nail psoriasis. Med J Aust 2007;186:424 (Pubitemid 46691866)
    • (2007) Medical Journal of Australia , vol.186 , Issue.8 , pp. 424
    • Sakata, S.1    Howard, A.2
  • 75
    • 0029148743 scopus 로고
    • Noninvasive investigation of human skin after in vivo iontophoresis
    • Thysman S, Van Neste D, Preat V. Noninvasive investigation of human skin after in vivo iontophoresis. Skin Pharmacol 1995;8:229-36
    • (1995) Skin Pharmacol , vol.8 , pp. 229-36
    • Thysman, S.1    Van Neste, D.2    Preat, V.3
  • 76
    • 33644768913 scopus 로고    scopus 로고
    • Recovery of human skin impedance in vivo after iontophoresis: Effect of metal ions
    • Curdy C, Kalia YN, Falson-Rieg F, et al. Recovery of human skin impedance in vivo after iontophoresis: effect of metal ions. AAPS PharmSci 2000;2:E23
    • (2000) AAPS PharmSci , vol.2
    • Curdy, C.1    Kalia, Y.N.2    Falson-Rieg, F.3
  • 78
    • 0034982822 scopus 로고    scopus 로고
    • Non-invasive assessment of the effects of iontophoresis on human skin in-vivo
    • DOI 10.1211/0022357011776117
    • Curdy C, Kalia YN, Guy RH. Non-invasive assessment of the effects of iontophoresis on human skin in-vivo. J Pharm Pharmacol 2001;53:769-77 (Pubitemid 32529719)
    • (2001) Journal of Pharmacy and Pharmacology , vol.53 , Issue.6 , pp. 769-777
    • Curdy, C.1    Kalia, Y.N.2    Guy, R.H.3
  • 79
    • 84255181140 scopus 로고    scopus 로고
    • Evaluation of the effect of iontophoresis on human nail in vitro by impedance and infrared spectroscopies
    • Benzeval I, Bowen CR, Guy RH, et al. Evaluation of the effect of iontophoresis on human nail in vitro by impedance and infrared spectroscopies. Skin Forum 11th Annual Meeting 2010, p.3
    • (2010) Skin Forum 11th Annual Meeting , pp. 3
    • Benzeval, I.1    Bowen, C.R.2    Guy, R.H.3
  • 80
    • 77950995335 scopus 로고    scopus 로고
    • Studies in drug transport vs. current in iontophoretic onychomycosis treatment
    • Barsness M, Davis SP, Etheredge R. Studies in drug transport vs. current in iontophoretic onychomycosis treatment. Conf Proc IEEE Eng Med Biol Soc 2009;289-94
    • (2009) Conf Proc IEEE Eng Med Biol Soc , pp. 289-94
    • Barsness, M.1    Davis, S.P.2    Etheredge, R.3
  • 82
    • 3242759069 scopus 로고    scopus 로고
    • Noninvasive glucose monitoring by reverse iontophoresis in vivo: Application of the internal standard concept
    • DOI 10.1373/clinchem.2004.032862
    • Sieg A, Guy RH, Delgado-Charro MB. Noninvasive glucose monitoring by reverse iontophoresis in vivo: application of the internal standard concept. Clin Chem 2004;50:1383-90 (Pubitemid 38970646)
    • (2004) Clinical Chemistry , vol.50 , Issue.8 , pp. 1383-1390
    • Sieg, A.1    Guy, R.H.2    Delgado-Charro, M.B.3
  • 83
    • 0346040093 scopus 로고    scopus 로고
    • The composite solubility versus pH profile and its role in intestinal absorption prediction
    • Hendriksen BA, Felix MV, Bolger MB. The composite solubility versus pH profile and its role in intestinal absorption prediction. AAPS PharmSci 2003;5:E4
    • (2003) AAPS PharmSci , vol.5
    • Hendriksen, B.A.1    Felix, M.V.2    Bolger, M.B.3
  • 84
    • 77952293446 scopus 로고    scopus 로고
    • Physicochemical characterization of terbinafine-cyclodextrin complexes in solution and in the solid state
    • Uzqueda M, Martin C, Zornoza A, et al. Physicochemical characterization of terbinafine-cyclodextrin complexes in solution and in the solid state. J Inc Phenom Macrocycl Chem 2010;66:393-402
    • (2010) J Inc Phenom Macrocycl Chem , vol.66 , pp. 393-402
    • Uzqueda, M.1    Martin, C.2    Zornoza, A.3
  • 85
    • 76949106263 scopus 로고    scopus 로고
    • Iontophoretic terbinafine delivery in onychomycosis: Questionable nail growth
    • Oon HH, Tan HH. Iontophoretic terbinafine delivery in onychomycosis: questionable nail growth. Br J Dermatol 2010;162:699-700
    • (2010) Br J Dermatol , vol.162 , pp. 699-700
    • Oon, H.H.1    Tan, H.H.2
  • 86
    • 33746225529 scopus 로고    scopus 로고
    • Different physicochemical properties of antimycotic agents are relevant for penetration into and through human nails
    • Neubert RHH, Gensbugel C, Jackel A, et al. Different physichochemical properties of antmycotic agents are relevant for penetration into and through human nails. Pharmazie 2006;61:604-7 (Pubitemid 44098027)
    • (2006) Pharmazie , vol.61 , Issue.7 , pp. 604-607
    • Neubert, R.H.H.1    Gensbugel, C.2    Jackel, A.3    Wartewig, S.4
  • 89
    • 1242351713 scopus 로고    scopus 로고
    • Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults
    • Courtney R, Wexler D, Radwanski E, et al. Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults. Br J Clin Pharmacol 2003;57:218-22
    • (2003) Br J Clin Pharmacol , vol.57 , pp. 218-22
    • Courtney, R.1    Wexler, D.2    Radwanski, E.3
  • 90
    • 79956079702 scopus 로고    scopus 로고
    • Review of fluconazole properties and analytical methods for its determination
    • 32
    • Ruela Correa JC, Nunes Salgado HR. Review of fluconazole properties and analytical methods for its determination. CRC CR Rev Anal Chem 2011;41:124:32
    • (2011) CRC CR Rev Anal Chem , vol.41 , pp. 124
    • Ruela Correa, J.C.1    Nunes Salgado, H.R.2
  • 91
    • 0030595303 scopus 로고    scopus 로고
    • Systematic approach to the treatment of enantiomeric separations in capillary electrophoresis and liquid chromatography III. A binding constant-retention factor relationship and effects of acetonitrile on the chiral separation of tioconazole
    • DOI 10.1016/0021-9673(96)00274-9
    • Ferguson PD, Goodall DM, Loran JS. Systematic approach to the treatment of enantiomeric separations in capillary electrophoresis and liquid chromatography. III A binding constant-retention factor relationship and effects of acetonitrile on the chiral separation of tioconazole. J Chromatogr A 1996;745:25-35 (Pubitemid 26319862)
    • (1996) Journal of Chromatography A , vol.745 , Issue.1-2 , pp. 25-35
    • Ferguson, P.D.1    Goodall, D.M.2    Loran, J.S.3
  • 92
    • 0023272276 scopus 로고
    • Drug release from thermosetting fatty vehicles filled into hard gelatin capsules
    • Howard JR, Gould PL. Drug release from thermosetting fatty vehicles filled into hard gelatin capsules. Drug Dev Ind Pharm 1987;13:1031-45 (Pubitemid 17100412)
    • (1987) Drug Development and Industrial Pharmacy , vol.13 , Issue.6 , pp. 1031-1045
    • Howard, J.R.1    Gould, P.L.2
  • 93
    • 79955045075 scopus 로고    scopus 로고
    • Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids
    • Thakur A, Kadam RS, Kompella UB. Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug Metab Dispos 2011;39:771-81
    • (2011) Drug Metab Dispos , vol.39 , pp. 771-81
    • Thakur, A.1    Kadam, R.S.2    Kompella, U.B.3


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