-
1
-
-
0000440615
-
Structural characteristics and permeability properties of the human nail: A review
-
Gupchup GV, Zatz JL. Structural characteristics and permeability properties of the human nail: a review. J Cosmet Sci 1999;50:363-85
-
(1999)
J Cosmet Sci
, vol.50
, pp. 363-385
-
-
Gupchup, G.V.1
Zatz, J.L.2
-
2
-
-
0037006909
-
Drug delivery to the nail following topical application
-
Murdan S, Drug delivery to the nail following topical application. Int J Pharm 2002;236:1-26
-
(2002)
Int J Pharm
, vol.236
, pp. 1-26
-
-
Murdan, S.1
-
3
-
-
57049096312
-
-
Editors. Percutaneous absorption. Drugs, Cosmetics, Mechanisms, Methodology. New York: Marcel Dekker Inc
-
Sun Y, Liu JC, Wang JCT, De Doncker P. Nail penetration. Focus on topical delivery of antifungal drugs for onychomycosis treatment. In: Bronaugh, RL, Maibach, HI, Editors. Percutaneous absorption. Drugs - Cosmetics - Mechanisms - Methodology. New York: Marcel Dekker Inc., 1999;759-87
-
(1999)
Nail penetration. Focus on topical delivery of antifungal drugs for onychomycosis treatment
, pp. 759-787
-
-
Sun, Y.1
Liu, J.C.2
Wang, J.C.T.3
De Doncker, P.4
-
4
-
-
57049119460
-
-
Murdan S. 1st meeting on topical drug delivery to the nail. Meeting abstract. Expert Opin Drug Deliv 2007;4:453-5 5 Halmy K. Experience with nail lacquers containing amorolfine 5% and ciclopirox 8% in patients with onychomycosis. J Am Acad Dermatol Suppl 2005;S150:P1821
-
Murdan S. 1st meeting on topical drug delivery to the nail. Meeting abstract. Expert Opin Drug Deliv 2007;4:453-5 5 Halmy K. Experience with nail lacquers containing amorolfine 5% and ciclopirox 8% in patients with onychomycosis. J Am Acad Dermatol Suppl 2005;S150:P1821
-
-
-
-
5
-
-
57049129187
-
-
NanoBio Corporation announces positive phase 1 clinical results for topical treatment for onychomycosis, available at, Last accessed 29 April 2008
-
NanoBio Corporation announces positive phase 1 clinical results for topical treatment for onychomycosis, available at http://www.nanobio.com/ News/NB-002_Phase1_Results.html [Last accessed 29 April 2008]
-
-
-
-
6
-
-
0030973380
-
Nail penetration of the antifungal agent oxiconazole after repeated topical application in healthy volunteers, and the effect of acetylcysteine
-
Van Hoogdalem EJ, Van den Hoven WE, Terpstra IJ, et al. Nail penetration of the antifungal agent oxiconazole after repeated topical application in healthy volunteers, and the effect of acetylcysteine. Eur J Pharm Sci 1997;5:119-27
-
(1997)
Eur J Pharm Sci
, vol.5
, pp. 119-127
-
-
Van Hoogdalem, E.J.1
Van den Hoven, W.E.2
Terpstra, I.J.3
-
7
-
-
0005660977
-
Basic science of the nail unit
-
Scher, R.K, Daniel, C.R, Editors, Philadelphia: WB Saunders
-
Fleckman P. Basic science of the nail unit, In: Scher, R.K., Daniel, C.R., Editors, Nails: Therapy, Diagnosis, Surgery. Philadelphia: WB Saunders, 1997;37-54
-
(1997)
Nails: Therapy, Diagnosis, Surgery
, pp. 37-54
-
-
Fleckman, P.1
-
9
-
-
34250204897
-
Psoriasis of the nail: Anatomy, pathology, clinical presentation, and a review of the literature on therapy
-
Jiaravuthisan MM, Sasseville D, Vender RB, et al. Psoriasis of the nail: anatomy, pathology, clinical presentation, and a review of the literature on therapy. J Am Acad Dermatol 2007;57:1-27
-
(2007)
J Am Acad Dermatol
, vol.57
, pp. 1-27
-
-
Jiaravuthisan, M.M.1
Sasseville, D.2
Vender, R.B.3
-
10
-
-
33846880369
-
The structure and properties of nails and periungual tissues
-
Forslind B, Linberg M, Norlén L, Editors, New York: Marcel Dekker;
-
De Berker D, Forslind B. The structure and properties of nails and periungual tissues. In: Forslind B, Linberg M, Norlén L, Editors. Skin, hair and nails, Structure and Function, New York: Marcel Dekker; 2004:409-64
-
(2004)
Skin, hair and nails, Structure and Function
, pp. 409-464
-
-
De Berker, D.1
Forslind, B.2
-
13
-
-
0024564696
-
Ultrasound structure of the human nail plate
-
Jemec GBE, Serup J. Ultrasound structure of the human nail plate. Arch Dermatol 1989;125:643-6
-
(1989)
Arch Dermatol
, vol.125
, pp. 643-646
-
-
Jemec, G.B.E.1
Serup, J.2
-
15
-
-
0013968149
-
The histochemistry of the human nail
-
Jarrett A, Spearman RIC. The histochemistry of the human nail. Arch Derm 1966;94:652-7
-
(1966)
Arch Derm
, vol.94
, pp. 652-657
-
-
Jarrett, A.1
Spearman, R.I.C.2
-
16
-
-
0033781077
-
A large-scale North American study of fungal isolates from nails: The frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns
-
Ghannoum MA, Hajjeh RA, Scher R, et al. A large-scale North American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns. J Am Acad Dermatol 2000;43:641-8
-
(2000)
J Am Acad Dermatol
, vol.43
, pp. 641-648
-
-
Ghannoum, M.A.1
Hajjeh, R.A.2
Scher, R.3
-
18
-
-
0026009008
-
The diagnosis of nail fungal infection
-
Daniel CR. The diagnosis of nail fungal infection. Arch Dermatol 1991;127:1566-7
-
(1991)
Arch Dermatol
, vol.127
, pp. 1566-1567
-
-
Daniel, C.R.1
-
19
-
-
0029764340
-
Onychomycosis: A significant medical disorder
-
Scher RK. Onychomycosis: a significant medical disorder. J Am Acad Dermatol 1996;35:S2-5
-
(1996)
J Am Acad Dermatol
, vol.35
-
-
Scher, R.K.1
-
20
-
-
0028137160
-
Topical and surgical treatment of onychomycosis
-
Cohen PR, Scher RK. Topical and surgical treatment of onychomycosis. J Am Acad Dermatol 1994;31:S74-7
-
(1994)
J Am Acad Dermatol
, vol.31
-
-
Cohen, P.R.1
Scher, R.K.2
-
23
-
-
45949095795
-
Review of antifungal therapy and the severity index for assessing onychomycosis: Part I
-
Baran R, Hay RJ, Garduno JI. Review of antifungal therapy and the severity index for assessing onychomycosis: Part I. J Dermatol Treat 2008;19:72-81
-
(2008)
J Dermatol Treat
, vol.19
, pp. 72-81
-
-
Baran, R.1
Hay, R.J.2
Garduno, J.I.3
-
25
-
-
33645662161
-
Topical and oral combination therapy for toenail onychomycosis - an updated review
-
Bristow IR, Baran R. Topical and oral combination therapy for toenail onychomycosis - an updated review. J Am Podiatr Med Assoc 2006;96:116-9
-
(2006)
J Am Podiatr Med Assoc
, vol.96
, pp. 116-119
-
-
Bristow, I.R.1
Baran, R.2
-
26
-
-
0031595796
-
Relapses of onychomycosis after successful treatment with systemic antifungals: A three-year follow-up
-
Tosti A, Piraccini BM, Stinchi C, Colombo MD. Relapses of onychomycosis after successful treatment with systemic antifungals: a three-year follow-up. Dermatology 1998;197:162-6
-
(1998)
Dermatology
, vol.197
, pp. 162-166
-
-
Tosti, A.1
Piraccini, B.M.2
Stinchi, C.3
Colombo, M.D.4
-
27
-
-
0142196749
-
Treatment failures and relapses in onychomycosis: A stubborn clinical problem
-
Arrese JE, Piérard GE. Treatment failures and relapses in onychomycosis: a stubborn clinical problem. Dermatology 2003;207:255-60
-
(2003)
Dermatology
, vol.207
, pp. 255-260
-
-
Arrese, J.E.1
Piérard, G.E.2
-
29
-
-
0030445353
-
Psoriasis of the nails associated with disability in a large number of patients: Results of a recent interview with 1, 728 patients
-
De Jong EM, Seegers BA, Gulinck MK, et al. Psoriasis of the nails associated with disability in a large number of patients: results of a recent interview with 1, 728 patients. Dermatology 1996;193:300-3
-
(1996)
Dermatology
, vol.193
, pp. 300-303
-
-
De Jong, E.M.1
Seegers, B.A.2
Gulinck, M.K.3
-
30
-
-
34147106954
-
Biological therapy and nail psoriasis
-
Lawry M. Biological therapy and nail psoriasis. Derm Ther 2007;20:60-7
-
(2007)
Derm Ther
, vol.20
, pp. 60-67
-
-
Lawry, M.1
-
31
-
-
0030768511
-
In vitro permeability of the human nail and of a keratin membrane from bovine hooves: Prediction of the penetration rate of antimycotics through the nail plate and their efficiency
-
Mertin D, Lippold BC. In vitro permeability of the human nail and of a keratin membrane from bovine hooves: prediction of the penetration rate of antimycotics through the nail plate and their efficiency. J Pharm Pharmacol 1997;49:866-72
-
(1997)
J Pharm Pharmacol
, vol.49
, pp. 866-872
-
-
Mertin, D.1
Lippold, B.C.2
-
32
-
-
1442309064
-
In vitro permeation of several drugs through the human nail plate: Relationship between physicochemical properties and nail permeability of drugs
-
Kobayashi Y, Komatsu T, Sumi M, et al. In vitro permeation of several drugs through the human nail plate: relationship between physicochemical properties and nail permeability of drugs. Eur J Pharm Sci 2004;21:471-7
-
(2004)
Eur J Pharm Sci
, vol.21
, pp. 471-477
-
-
Kobayashi, Y.1
Komatsu, T.2
Sumi, M.3
-
33
-
-
0020660430
-
Physicochemical characterisation of the human nail: Permeation pattern for water and the homologous alcohols and differences with respect to the stratum corneum
-
Walters KA, Flynn GL, Marvel JR. Physicochemical characterisation of the human nail: permeation pattern for water and the homologous alcohols and differences with respect to the stratum corneum. J Pharm Pharmacol 1983;35:28-33
-
(1983)
J Pharm Pharmacol
, vol.35
, pp. 28-33
-
-
Walters, K.A.1
Flynn, G.L.2
Marvel, J.R.3
-
34
-
-
0031015804
-
In vitro permeability of the human nail and of a keratin membrane from bovine hooves: Influence of the partition coefficient octanol/water and the water solubility of drugs on their permeability and maximum flux
-
Mertin D, Lippold BC. In vitro permeability of the human nail and of a keratin membrane from bovine hooves: influence of the partition coefficient octanol/water and the water solubility of drugs on their permeability and maximum flux. J Pharm Pharmacol 1997;49:30-4
-
(1997)
J Pharm Pharmacol
, vol.49
, pp. 30-34
-
-
Mertin, D.1
Lippold, B.C.2
-
36
-
-
0020576881
-
Characterisation of the proteins of human hair and nail by electrophoresis
-
Marshall RC. Characterisation of the proteins of human hair and nail by electrophoresis. J Invest Dermatol 1983;80:519-24
-
(1983)
J Invest Dermatol
, vol.80
, pp. 519-524
-
-
Marshall, R.C.1
-
37
-
-
0021828923
-
-
Walters KA, Flynn GL, Marvel JR. Penetration of the human nail plate: the effects of vehicle pH on the permeation of miconazole, J Pharm Pharmacol 1985;37:498-9
-
"Walters KA, Flynn GL, Marvel JR. Penetration of the human nail plate: the effects of vehicle pH on the permeation of miconazole, J Pharm Pharmacol 1985;37:498-9
-
-
-
-
38
-
-
0031911670
-
Subungual dermatophytoma complicating dermatophyte onychomycosis
-
Roberts DT, Evans EG. Subungual dermatophytoma complicating dermatophyte onychomycosis. Br J Dermatol 1998;138:189-90
-
(1998)
Br J Dermatol
, vol.138
, pp. 189-190
-
-
Roberts, D.T.1
Evans, E.G.2
-
39
-
-
0032946662
-
Drug permeation through the three layers of the human nail plate
-
Kobayashi Y, Miyamoto M, Sugibayashi K, Morimoto, Y. Drug permeation through the three layers of the human nail plate. J Pharm Pharmacol 1999;51:271-8
-
(1999)
J Pharm Pharmacol
, vol.51
, pp. 271-278
-
-
Kobayashi, Y.1
Miyamoto, M.2
Sugibayashi, K.3
Morimoto, Y.4
-
40
-
-
0026922265
-
-
Pittrof F, Gerhards J, Erni W, Klecak G. Loceryl(nail lacquer - realisation of a new galenical approach to onychomycosis therapy. Clin Exp Dermatol 1992;17(Suppl 1):26-8
-
Pittrof F, Gerhards J, Erni W, Klecak G. Loceryl(nail lacquer - realisation of a new galenical approach to onychomycosis therapy. Clin Exp Dermatol 1992;17(Suppl 1):26-8
-
-
-
-
41
-
-
0026640773
-
Comparative efficacy and safety of amorolfine nail lacquer 2-percent versus 5-percent once weekly
-
Lauharanta J. Comparative efficacy and safety of amorolfine nail lacquer 2-percent versus 5-percent once weekly. Clin Exp Dermatol 1992;17:41-3
-
(1992)
Clin Exp Dermatol
, vol.17
, pp. 41-43
-
-
Lauharanta, J.1
-
42
-
-
84980111648
-
The treatment of onychomycosis with griseofulvin
-
Hargreaves GK. The treatment of onychomycosis with griseofulvin. Br J Dermatol 1960;72:358-64
-
(1960)
Br J Dermatol
, vol.72
, pp. 358-364
-
-
Hargreaves, G.K.1
-
43
-
-
15744382593
-
Topical treatment of onychomycosis with an electrically driven high-speed grinder
-
Fukuda T, Shiohara T. Topical treatment of onychomycosis with an electrically driven high-speed grinder. Jpn J Dermatol 2001;111:37-42
-
(2001)
Jpn J Dermatol
, vol.111
, pp. 37-42
-
-
Fukuda, T.1
Shiohara, T.2
-
44
-
-
34250786939
-
Evaluation of a nail grinding system using an electronic high-speed dental teeth grinder in patients with onychomycosis
-
Kishimoto K. Evaluation of a nail grinding system using an electronic high-speed dental teeth grinder in patients with onychomycosis. Jpn J Dermatol 2005;115:1035-40
-
(2005)
Jpn J Dermatol
, vol.115
, pp. 1035-1040
-
-
Kishimoto, K.1
-
45
-
-
34250772898
-
Effects of foot care intervention including nail drilling combined with topical antifungal application in diabetic patients with onychomycosis
-
Sumikawa M, Egawa T, Honda I, et al. Effects of foot care intervention including nail drilling combined with topical antifungal application in diabetic patients with onychomycosis. J Dermatol 2007;34:456-64
-
(2007)
J Dermatol
, vol.34
, pp. 456-464
-
-
Sumikawa, M.1
Egawa, T.2
Honda, I.3
-
46
-
-
0036803955
-
Nail morphology studies as assessments for onychomycosis treatment modalities
-
Repka MA, O'Haver J, See CH, et al. Nail morphology studies as assessments for onychomycosis treatment modalities. Int J Pharm 2002;245:25-36
-
(2002)
Int J Pharm
, vol.245
, pp. 25-36
-
-
Repka, M.A.1
O'Haver, J.2
See, C.H.3
-
47
-
-
4444235907
-
Influence of human nail etching for the assessment of topical onychomycosis therapies
-
Repka MA, Mididoddi PK, Stodghill SP. Influence of human nail etching for the assessment of topical onychomycosis therapies. Int J Pharm 2004;282:95-106
-
(2004)
Int J Pharm
, vol.282
, pp. 95-106
-
-
Repka, M.A.1
Mididoddi, P.K.2
Stodghill, S.P.3
-
49
-
-
57049173795
-
-
available from, Last accessed 29 April 2008
-
Pathformer: better than a hot paper clip, available from http://medgadget.com/archives/2006/06/pathformer_bett.html [Last accessed 29 April 2008]
-
Pathformer: Better than a hot paper clip
-
-
-
50
-
-
57049161279
-
A randomised, double-blind, placebo-controlled, pilot study of 1% terbinafine cream applied twice daily and delivered via nail plate microporation for the treatment of subungual toenail onychomycosis
-
Boker A, Cioccon D, Kimball A. A randomised, double-blind, placebo-controlled, pilot study of 1% terbinafine cream applied twice daily and delivered via nail plate microporation for the treatment of subungual toenail onychomycosis. J Am Acad Dermatol 2007;56:AB114
-
(2007)
J Am Acad Dermatol
, vol.56
-
-
Boker, A.1
Cioccon, D.2
Kimball, A.3
-
52
-
-
57049139180
-
-
available from, Last accessed 03 July 2008
-
Transdermal and transungual microconduits, available from http://carlislescientific.com/news.html [Last accessed 03 July 2008]
-
Transdermal and transungual microconduits
-
-
-
53
-
-
57049166334
-
-
Mididoddi P, Upadhye S, Raymond C, et al. Influence of etching and ultrasound on the permeability of ciclopirox through the human nail. AAPS J 2006;8(S2):R6114
-
Mididoddi P, Upadhye S, Raymond C, et al. Influence of etching and ultrasound on the permeability of ciclopirox through the human nail. AAPS J 2006;8(S2):R6114
-
-
-
-
54
-
-
57049113070
-
-
Torkar A, Kristl J, Murdan S. Low-frequency ultrasound to enhance topical drug delivery to the nail. AAPS J 2007;9(S2)T3221
-
Torkar A, Kristl J, Murdan S. Low-frequency ultrasound to enhance topical drug delivery to the nail. AAPS J 2007;9(S2)T3221
-
-
-
-
55
-
-
1542328828
-
Low-frequency sonophoresis - a review
-
Mitragotri S, Kost J. Low-frequency sonophoresis - a review. Adv Drug Del Rev 2004;56:589-601
-
(2004)
Adv Drug Del Rev
, vol.56
, pp. 589-601
-
-
Mitragotri, S.1
Kost, J.2
-
59
-
-
57049116922
-
-
Ramaswamy C, Kim H, Friden P, Murdan S. Iontophoresis to enhance topical delivery of terbinafine to the nail. AAPS J 2007;9(S2):T3086 poster available from: http://www.scienceposters-online.net/download/ ?poster_id=126 Accessed 26 September 2008
-
Ramaswamy C, Kim H, Friden P, Murdan S. Iontophoresis to enhance topical delivery of terbinafine to the nail. AAPS J 2007;9(S2):T3086 poster available from: http://www.scienceposters-online.net/download/ ?poster_id=126 Accessed 26 September 2008
-
-
-
-
60
-
-
39749153039
-
Transungual iontophoretic transport of polar neutral and positively charged model permeants: Effects of electrophoresis and electroosmosis
-
Hao J, Li SK. Transungual iontophoretic transport of polar neutral and positively charged model permeants: effects of electrophoresis and electroosmosis. J Pharm Sci 2008;97:893-905
-
(2008)
J Pharm Sci
, vol.97
, pp. 893-905
-
-
Hao, J.1
Li, S.K.2
-
61
-
-
57049159644
-
Mechanistic study of electroosmotic transport across hydrated nail plates: Effects of pH and ionic strength
-
3 April
-
Hao J, Li SK. Mechanistic study of electroosmotic transport across hydrated nail plates: effects of pH and ionic strength. J Pharm Sci 2008;3 April
-
(2008)
J Pharm Sci
-
-
Hao, J.1
Li, S.K.2
-
62
-
-
42749095174
-
Chemical method to enhance transungual transport and iontophoresis efficiency
-
Hao J, Smith KA, Li SK. Chemical method to enhance transungual transport and iontophoresis efficiency. Int J Pharm 2008;357:61-9
-
(2008)
Int J Pharm
, vol.357
, pp. 61-69
-
-
Hao, J.1
Smith, K.A.2
Li, S.K.3
-
65
-
-
0020036631
-
Bioavailability, skin- and nail-penetration of topically applied antimycotics
-
Stuttgen G, Bauer E. Bioavailability, skin- and nail-penetration of topically applied antimycotics. Mycosen 1982;25:74-80
-
(1982)
Mycosen
, vol.25
, pp. 74-80
-
-
Stuttgen, G.1
Bauer, E.2
-
66
-
-
0001361886
-
Topical pharmacology and toxicology of dimethyl sulfoxide
-
Kligman AM. Topical pharmacology and toxicology of dimethyl sulfoxide. J Am Med Assoc 1965;193:796-804
-
(1965)
J Am Med Assoc
, vol.193
, pp. 796-804
-
-
Kligman, A.M.1
-
67
-
-
0006370798
-
Human nail and its topical treatment: Brief review of current research and development of topical antifungal drug delivery for onychomycosis treatment
-
Wang JCT, Sun Y. Human nail and its topical treatment: brief review of current research and development of topical antifungal drug delivery for onychomycosis treatment. J Cosmet Sci 1998;71-76
-
(1998)
J Cosmet Sci
, pp. 71-76
-
-
Wang, J.C.T.1
Sun, Y.2
-
68
-
-
0036167779
-
Investigation of nail permeation enhancement by chemical modification using water as a probe
-
Malhotra GG, Zatz JL. Investigation of nail permeation enhancement by chemical modification using water as a probe. J Pharm Sci 2002; 91: 312-23
-
(2002)
J Pharm Sci
, vol.91
, pp. 312-323
-
-
Malhotra, G.G.1
Zatz, J.L.2
-
70
-
-
0031730650
-
Enhancing effect of N-acetyl-L-cysteine or 2-mercaptoethanol on the in vitro permeation of 5-fluorouracil or tolnaftate through the human nail plate
-
Kobayashi Y, Miyamoto M, Sugibayashi K, Morimoto Y. Enhancing effect of N-acetyl-L-cysteine or 2-mercaptoethanol on the in vitro permeation of 5-fluorouracil or tolnaftate through the human nail plate. Chem Pharm Bull 1998;46:1797-802
-
(1998)
Chem Pharm Bull
, vol.46
, pp. 1797-1802
-
-
Kobayashi, Y.1
Miyamoto, M.2
Sugibayashi, K.3
Morimoto, Y.4
-
71
-
-
35948959948
-
Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers
-
Khengar RH, Jones SA, Turner RB, et al. Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers. Pharm Res 2007;24:2207-12
-
(2007)
Pharm Res
, vol.24
, pp. 2207-2212
-
-
Khengar, R.H.1
Jones, S.A.2
Turner, R.B.3
-
72
-
-
0012587817
-
Equilibrium constants of the reactions of sulfite with cystine and with dithiodiglycolic acid
-
Stricks W, Kolthoff IM. Equilibrium constants of the reactions of sulfite with cystine and with dithiodiglycolic acid. J Am Chem Soc 1951;73:4569-74
-
(1951)
J Am Chem Soc
, vol.73
, pp. 4569-4574
-
-
Stricks, W.1
Kolthoff, I.M.2
-
73
-
-
57049178806
-
-
Ng Y, Mohorcic M, Torkar A, et al. Sodium sulphite - a potential onycheal enhancer to increase the topical drug delivery to the nail. AAPS J 2007;9(S2):T3181
-
Ng Y, Mohorcic M, Torkar A, et al. Sodium sulphite - a potential onycheal enhancer to increase the topical drug delivery to the nail. AAPS J 2007;9(S2):T3181
-
-
-
-
74
-
-
57049164688
-
The use of a novel ungual penetration enhancing technology, MedNail to demonstrate that disulphide bond disruption in the nail increases the permeability of three antifungal agents
-
London, 25-6 June
-
Khengar RH, Jones SA, Brown MB. The use of a novel ungual penetration enhancing technology, MedNail to demonstrate that disulphide bond disruption in the nail increases the permeability of three antifungal agents. Proc Skin Forum 2008, London, 25-6 June
-
(2008)
Proc Skin Forum
-
-
Khengar, R.H.1
Jones, S.A.2
Brown, M.B.3
-
75
-
-
0031862902
-
The effect of keratolytic agents on the permeability of three imidazole antimycotic drugs through the human nail
-
Quintanar-Guerrero D, Ganem-Quintanar A, Tapia-Olguin P, et al. The effect of keratolytic agents on the permeability of three imidazole antimycotic drugs through the human nail. Drug Dev Ind Pharm 1998;24:685-90
-
(1998)
Drug Dev Ind Pharm
, vol.24
, pp. 685-690
-
-
Quintanar-Guerrero, D.1
Ganem-Quintanar, A.2
Tapia-Olguin, P.3
-
76
-
-
14144256248
-
Combination of fluconazole and urea in a nail lacquer for treating onychomycosis
-
Baran R, Coquard F. Combination of fluconazole and urea in a nail lacquer for treating onychomycosis. J Dermatolog Treat 2005;16:52-5
-
(2005)
J Dermatolog Treat
, vol.16
, pp. 52-55
-
-
Baran, R.1
Coquard, F.2
-
77
-
-
0018152678
-
Urea ointment in the non-surgical avulsion of nail dystrophies
-
Farber EM, South DA. Urea ointment in the non-surgical avulsion of nail dystrophies. Cutis 1978;22:689-92
-
(1978)
Cutis
, vol.22
, pp. 689-692
-
-
Farber, E.M.1
South, D.A.2
-
78
-
-
0037001207
-
Chemical avulsion with urea nail lacquer
-
Baran R, Tosti A. Chemical avulsion with urea nail lacquer. J Dermatol Treat 2002;13:161-4
-
(2002)
J Dermatol Treat
, vol.13
, pp. 161-164
-
-
Baran, R.1
Tosti, A.2
-
79
-
-
0022359715
-
Physicochemical characterisation of the human nail: Solvent effects on the permeation of homologous alcohols
-
Walters KA, Flynn GL, Marvel JR. Physicochemical characterisation of the human nail: solvent effects on the permeation of homologous alcohols. J Pharm Pharmacol 1985;37:771-5
-
(1985)
J Pharm Pharmacol
, vol.37
, pp. 771-775
-
-
Walters, K.A.1
Flynn, G.L.2
Marvel, J.R.3
-
80
-
-
0030975475
-
In vitro permeability of the human nail and of a keratin membrane from bovine hooves: Penetration of chloramphenicol from lipophilic vehicles and a nail lacquer
-
Mertin D, Lippold BC. In vitro permeability of the human nail and of a keratin membrane from bovine hooves: penetration of chloramphenicol from lipophilic vehicles and a nail lacquer. J Pharm Pharmacol 1997;49:241-5
-
(1997)
J Pharm Pharmacol
, vol.49
, pp. 241-245
-
-
Mertin, D.1
Lippold, B.C.2
-
81
-
-
35748948955
-
Effect of hydration on the permeation of ketoconazole through human nail plate in vitro
-
Gunt BH, Kasting GB. Effect of hydration on the permeation of ketoconazole through human nail plate in vitro Eur J Pharm Sci 2007;32:254-60
-
(2007)
Eur J Pharm Sci
, vol.32
, pp. 254-260
-
-
Gunt, B.H.1
Kasting, G.B.2
-
83
-
-
33846888289
-
An investigation into keratinolytic enzymes to enhance ungual drug delivery
-
Mohorcic M, Torkar A, Friedrich J, et al. An investigation into keratinolytic enzymes to enhance ungual drug delivery, Int J Pharm 2007;332:196-201
-
(2007)
Int J Pharm
, vol.332
, pp. 196-201
-
-
Mohorcic, M.1
Torkar, A.2
Friedrich, J.3
-
84
-
-
33749478702
-
Influence of tartaric acid on the bioadhesion and mechanical properties of hot-melt extruded hydroxypropyl cellulose films for the human nail
-
Mididoddi PK, Prodduturi S, Repka MA. Influence of tartaric acid on the bioadhesion and mechanical properties of hot-melt extruded hydroxypropyl cellulose films for the human nail. Drug Dev Indus Pharm 2006;32:1059-66
-
(2006)
Drug Dev Indus Pharm
, vol.32
, pp. 1059-1066
-
-
Mididoddi, P.K.1
Prodduturi, S.2
Repka, M.A.3
-
85
-
-
33947161961
-
Characterization of hot-melt extruded drug delivery systems for onychomycosis
-
Mididoddi PK, Repka MA. Characterization of hot-melt extruded drug delivery systems for onychomycosis. Eur J Pharm Biopharm 2007;66:95-105
-
(2007)
Eur J Pharm Biopharm
, vol.66
, pp. 95-105
-
-
Mididoddi, P.K.1
Repka, M.A.2
-
87
-
-
0242302566
-
Permeation of ciclopirox across porcine hoof membrane: Effect of pressure sensitive adhesives and vehicles
-
Myoung Y, Choi HK. Permeation of ciclopirox across porcine hoof membrane: effect of pressure sensitive adhesives and vehicles. Eur J Pharm Sci 2003;20:319-25
-
(2003)
Eur J Pharm Sci
, vol.20
, pp. 319-325
-
-
Myoung, Y.1
Choi, H.K.2
-
88
-
-
14844312114
-
Bioadhesive patch-based delivery of 5-aminolevulinic acid to the nail for photodynamic therapy of onychomycosis
-
Donnelly RF, McCarron PA, Lightowler JM, Woolfson AD. Bioadhesive patch-based delivery of 5-aminolevulinic acid to the nail for photodynamic therapy of onychomycosis. J Control Rel 2005;103:381-92
-
(2005)
J Control Rel
, vol.103
, pp. 381-392
-
-
Donnelly, R.F.1
McCarron, P.A.2
Lightowler, J.M.3
Woolfson, A.D.4
-
89
-
-
33747169865
-
Nail penetration of sertaconazole with a sertaconazole-containing nail patch formulation
-
Susilo R, Korting HC, Greb W, Strauss UP. Nail penetration of sertaconazole with a sertaconazole-containing nail patch formulation. Am J Clin Dermatol 2006;7:259-62
-
(2006)
Am J Clin Dermatol
, vol.7
, pp. 259-262
-
-
Susilo, R.1
Korting, H.C.2
Greb, W.3
Strauss, U.P.4
-
90
-
-
23944460513
-
In vitro antimycotic activity and nail permeation models of a piroctone olamine (Octopirox) containing transungual water soluble technology
-
Dubini F, Bellotti MG, Frangi A, et al. In vitro antimycotic activity and nail permeation models of a piroctone olamine (Octopirox) containing transungual water soluble technology. Arzneimittel Forschung Drug Res 2005;55:478-83
-
(2005)
Arzneimittel Forschung Drug Res
, vol.55
, pp. 478-483
-
-
Dubini, F.1
Bellotti, M.G.2
Frangi, A.3
-
91
-
-
12844282890
-
In vitro transungual permeation of ciclopirox from a hydroxypropyl chitosan-based, water-soluble nail lacquer
-
Monti D, Saccomani L, Chetoni P, et al. In vitro transungual permeation of ciclopirox from a hydroxypropyl chitosan-based, water-soluble nail lacquer. Drug Dev Indus Pharm 2005;31:11-7
-
(2005)
Drug Dev Indus Pharm
, vol.31
, pp. 11-17
-
-
Monti, D.1
Saccomani, L.2
Chetoni, P.3
-
92
-
-
12244258225
-
Enhanced econazole penetration into human nail by 2-n-nonyl-1,3-dioxolane
-
Hui XY, Chan TCK, Barbadillo S, et al. Enhanced econazole penetration into human nail by 2-n-nonyl-1,3-dioxolane. J Pharm Sci 2003;92:142-8
-
(2003)
J Pharm Sci
, vol.92
, pp. 142-148
-
-
Hui, X.Y.1
Chan, T.C.K.2
Barbadillo, S.3
-
93
-
-
0006383561
-
Effect of nail polish on the hydration of the fingernail
-
Spruit D. Effect of nail polish on the hydration of the fingernail. Am Cosmetics Perfumery 1972;87:57-8
-
(1972)
Am Cosmetics Perfumery
, vol.87
, pp. 57-58
-
-
Spruit, D.1
-
94
-
-
52949122473
-
A few aspects of transonychial water loss (TOWL): Inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish
-
6 June
-
Murdan S, Hinsu D, Guimier M. A few aspects of transonychial water loss (TOWL): inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish. Eur J Pharm Biopharm 2008;published online 6 June 2008
-
(2008)
Eur J Pharm Biopharm 2008;published online
-
-
Murdan, S.1
Hinsu, D.2
Guimier, M.3
-
95
-
-
0028961164
-
Amorolfine nail lacquer: A novel formulation
-
Marty JP. Amorolfine nail lacquer: a novel formulation, J Eur Acad Dermatol Venereol 1995;4(Suppl 1)S17-21
-
(1995)
J Eur Acad Dermatol Venereol
, vol.4
, Issue.SUPPL. 1
-
-
Marty, J.P.1
-
98
-
-
34250205522
-
Ciclopirox 8% nail lacquer topical solution for the treatment of onychomycosis in patients with diabetes: A multicenter, open-label study
-
Brenner MA, Harkless LB, Mendicino RW, Page JC. Ciclopirox 8% nail lacquer topical solution for the treatment of onychomycosis in patients with diabetes: a multicenter, open-label study. J Am Podiatr Med Assoc 2007;97:195-202
-
(2007)
J Am Podiatr Med Assoc
, vol.97
, pp. 195-202
-
-
Brenner, M.A.1
Harkless, L.B.2
Mendicino, R.W.3
Page, J.C.4
-
99
-
-
34250652007
-
A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral terbinafine compared with oral terbinafine alone for the treatment of onychomycosis with matrix involvement
-
Baran R, Sigurgeirsson B, de Berker D, et al. A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral terbinafine compared with oral terbinafine alone for the treatment of onychomycosis with matrix involvement. Br J Dermatol 2007;157:149-57
-
(2007)
Br J Dermatol
, vol.157
, pp. 149-157
-
-
Baran, R.1
Sigurgeirsson, B.2
de Berker, D.3
-
100
-
-
57049143534
-
A randomized, controlled, dose-ranging study to assess the efficacy and safety of terbinafine HCl nail lacquer for onychomycosis
-
Gupta A, Mo YJ, Lu M. A randomized, controlled, dose-ranging study to assess the efficacy and safety of terbinafine HCl nail lacquer for onychomycosis. J Am Acad Dermatol 2006;54(Suppl. S)AB148
-
(2006)
J Am Acad Dermatol
, vol.54
, Issue.SUPPL. S
-
-
Gupta, A.1
Mo, Y.J.2
Lu, M.3
-
101
-
-
57049183445
-
-
Chan TC, Czarniecki C, Burrows W, et al. EcoNail (TM) (5% econazole plus 18% SEPA (R) nail lacquer in patients with severe onychomycosis: safety, local tolerability, and systemic exposure. J Invest Dermatol 2005;125:A4-A4926;Article no. 926
-
Chan TC, Czarniecki C, Burrows W, et al. EcoNail (TM) (5% econazole plus 18% SEPA (R) nail lacquer in patients with severe onychomycosis: safety, local tolerability, and systemic exposure. J Invest Dermatol 2005;125:A4-A4926;Article no. 926
-
-
-
-
102
-
-
28544446715
-
Treatment of nail psoriasis with 8% clobetasol nail lacquer: Positive experience in 10 patients
-
Regana MS, Ezquerra GM, Millet PU, Mateos FL. Treatment of nail psoriasis with 8% clobetasol nail lacquer: positive experience in 10 patients. J Eur Acad Dermatol Venereol 2005;19:573-7
-
(2005)
J Eur Acad Dermatol Venereol
, vol.19
, pp. 573-577
-
-
Regana, M.S.1
Ezquerra, G.M.2
Millet, P.U.3
Mateos, F.L.4
-
103
-
-
57049168518
-
Nail varnish as a drug delivery vehicle
-
Spring/Summer
-
Murdan S. Nail varnish as a drug delivery vehicle. The Drug Delivery Companies Report, 2004; Spring/Summer: 40-42
-
(2004)
The Drug Delivery Companies Report
, pp. 40-42
-
-
Murdan, S.1
-
104
-
-
34547635936
-
AN-2690, a novel antifungal for the topical treatment of onychomycosis
-
Barak O, Loo DS. AN-2690, a novel antifungal for the topical treatment of onychomycosis. Curr Opin Investig Drugs 2007;8:662-8
-
(2007)
Curr Opin Investig Drugs
, vol.8
, pp. 662-668
-
-
Barak, O.1
Loo, D.S.2
-
105
-
-
35348994986
-
In vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate
-
Hui X, Baker SJ, Wester RC, et al. In vitro penetration of a novel oxaborole antifungal (AN2690) into the human nail plate. J Pharm Sci 2007;96:2622-31
-
(2007)
J Pharm Sci
, vol.96
, pp. 2622-2631
-
-
Hui, X.1
Baker, S.J.2
Wester, R.C.3
-
106
-
-
1842863494
-
Antifungal drug response in an in vitro model of dermatophyte nail infection
-
Osborne CS, Leitner I, Favre B, Ryder NS. Antifungal drug response in an in vitro model of dermatophyte nail infection. Med Mycol 2004;42:159-63
-
(2004)
Med Mycol
, vol.42
, pp. 159-163
-
-
Osborne, C.S.1
Leitner, I.2
Favre, B.3
Ryder, N.S.4
-
107
-
-
57049087852
-
A multi-model approach for the evaluation of topical antifungal agents and formulations for the treatment of onychomycosis, Focus on Fungal Infections 17, San Diego, CA
-
Last accessed 02/07/08
-
Lenn J, Chern W, Buchta R, et al. A multi-model approach for the evaluation of topical antifungal agents and formulations for the treatment of onychomycosis, Focus on Fungal Infections 17, San Diego, CA, 7-9th March 2007, poster available from: http://www.medpharm.co.uk/ news/documents/2007FocusAntifungal_posterl.pdf, Last accessed 02/07/08
-
7-9th March 2007, poster available from
-
-
Lenn, J.1
Chern, W.2
Buchta, R.3
-
108
-
-
57049163381
-
An investigation into correlations between onycheal antifungal drug flux and resulting fungal inhibition in in vitro assays
-
London, 25-6 June
-
Meng W, Li HY, Ashbee R, et al. An investigation into correlations between onycheal antifungal drug flux and resulting fungal inhibition in in vitro assays. Proc Skin Forum 2008, London, 25-6 June
-
(2008)
Proc Skin Forum
-
-
Meng, W.1
Li, H.Y.2
Ashbee, R.3
-
109
-
-
0034754026
-
A plea to bridge the gap between antifungals and the management of onychomycosis. Current opinion
-
Arrese JE, Pierard-Franchimont C, Pierard GE. A plea to bridge the gap between antifungals and the management of onychomycosis. Current opinion Am J Clin Dermatol 2001;2:281-4
-
(2001)
Am J Clin Dermatol
, vol.2
, pp. 281-284
-
-
Arrese, J.E.1
Pierard-Franchimont, C.2
Pierard, G.E.3
|