Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

Neurobiology of Learning and Memory

Volumn 97, Issue 1, 2012, Pages 17-29

  Gerstein, Hilary ^a,b   O'Riordan, Kenneth ^a   Osting, Sue ^a   Schwarz, Martin ^c   Burger, Corinna ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

Astrocytes; Cognitive impairment; Gene transfer; Hippocampus; LTP; Metabotropic glutamate receptor

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; PARVOVIRUS VECTOR; PROTEIN HOMER 1;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CONVALESCENCE; DRUG MECHANISM; FEMALE; FREQUENCY MODULATION; GENE FUNCTION; GENE INACTIVATION; HIPPOCAMPAL CA1 REGION; IN VITRO STUDY; LEARNING DISORDER; LONG TERM POTENTIATION; MALE; MAZE TEST; MENTAL PERFORMANCE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; SPATIAL DISCRIMINATION; THETA RHYTHM; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ANIMALS; BEHAVIOR, ANIMAL; BENZOATES; CARRIER PROTEINS; GENE TRANSFER TECHNIQUES; GLYCINE; HIPPOCAMPUS; MAZE LEARNING; MICE; MICE, KNOCKOUT; NEURONAL PLASTICITY; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; RECOGNITION (PSYCHOLOGY); SOCIAL BEHAVIOR; SYNAPSES;

EID: 84155195217     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2011.08.009     Document Type: Article

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