The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region

Brain Research

Volumn 1022, Issue 1-2, 2004, Pages 12-18

  Francesconi, Walter ^a,b,c   Cammalleri, Maurizio ^a,b   Sanna, Pietro Paolo ^a,c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF PISA   (Italy)

^c Jolla CA USA Pietro Paolo Sanna   (United States)

Author keywords

Excitatory postsynaptic potential; Memory; Metabotropic glutamate receptor; Synaptic plasticity

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID; S6 KINASE; THREONINE;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN SLICE; CONTROLLED STUDY; DENDRITE; DRUG ACTIVITY; DRUG EFFECT; DRUG UTILIZATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; INHIBITION KINETICS; LONG TERM POTENTIATION; MUTANT; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SYNAPSE; TIME;

ANIMALS; ANIMALS, NEWBORN; BENZOATES; DENDRITES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLYCINE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LONG-TERM POTENTIATION; NEURONS; PHOSPHORYLATION; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; THREONINE; TIME FACTORS;

EID: 4444361472     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.06.060     Document Type: Article

References (30)

1. A. Aiba, C. Chen, K. Herrup, C. Rosenmund, C.F. Stevens, and S. Tonegawa Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice Cell 79 1994 365 375
2. R. Anwyl Metabotropic glutamate receptors: electrophysiological properties and role in plasticity Brain Res. Brain Res. Rev. 29 1999 83 120
3. Z.I. Bashir, Z.A. Bortolotto, C.H. Davies, N. Berretta, A.J. Irving, A.J. Seal, J.M. Henley, D.E. Jane, J.C. Watkins, and G.L. Collingridge Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors Nature 363 1993 347 350
4. A. Berthele, D.J. Laurie, S. Platzer, W. Zieglgansberger, T.R. Tolle, and B. Sommer Differential expression of rat and human type I metabotropic glutamate receptor splice variant messenger RNAs Neuroscience 85 1998 733 749
5. Z.A. Bortolotto, Z.I. Bashir, C.H. Davies, and G.L. Collingridge A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation Nature 368 1994 740 743
6. M. Cammalleri, R. Lutjens, F. Berton, A.R. King, C. Simpson, W. Francesconi, and P.P. Sanna Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1 Proc. Natl. Acad. Sci. U. S. A. 100 2003 14368 14373
7. P. Chinestra, L. Aniksztejn, D. Diabira, and Y. Ben-Ari (RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons J. Neurophysiol. 70 1993 2684 2689
8. B. Clark, S. Baker, J. Goldsworthy, J. Harris, and A. Kingston (+)-2-Methyl-4-carboxyphenylglycine (LY367385) selectively antagonizes metabotropic glutamate mGluR1 receptors Bioorg. Med. Chem. Lett. 7 1997 2777 2780
9. P.J. Conn, and J.P. Pin Pharmacology and functions of metabotropic glutamate receptors Annu. Rev. Pharmacol. Toxicol. 37 1997 205 237
10. F. Conquet, Z.I. Bashir, C.H. Davies, H. Daniel, F. Ferraguti, F. Bordi, K. Franz-Bacon, A. Reggiani, V. Matarese, and F. Conde Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1 Nature 372 1994 237 243
11. U. Frey, Y.Y. Huang, and E.R. Kandel Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons Science 260 1993 1661 1664
12. F. Gasparini, K. Lingenhohl, N. Stoehr, P.J. Flor, M. Heinrich, I. Vranesic, M. Biollaz, H. Allgeier, R. Heckendorn, S. Urwyler, M.A. Varney, E.C. Johnson, S.D. Hess, S.P. Rao, A.I. Sacaan, E.M. Santori, G. Velicelebi, and R. Kuhn 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist Neuropharmacology 38 1999 1493 1503
13. D.R. Ireland, and W.C. Abraham Group I mGluRs increase excitability of hippocampal CA1 pyramidal neurons by a PLC-independent mechanism J. Neurophysiol. 88 2002 107 116
14. J.A. Kerner, D.G. Standaert, J.B. Penney Jr., A.B. Young, and G.B. Landwehrmeyer Expression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum, neocortex, and hippocampus Brain Res. Mol. Brain Res. 48 1997 259 269
15. Y.M. Lu, Z. Jia, C. Janus, J.T. Henderson, R. Gerlai, J.M. Wojtowicz, and J.C. Roder Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP J. Neurosci. 17 1997 5196 5205
16. R. Lujan, Z. Nusser, J.D. Roberts, R. Shigemoto, and P. Somogyi Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus Eur. J. Neurosci. 8 1996 1488 1500
17. R. Lujan, J.D. Roberts, R. Shigemoto, H. Ohishi, and P. Somogyi Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites J. Chem. Neuroanat. 13 1997 219 241
18. G. Mannaioni, M.J. Marino, O. Valenti, S.F. Traynelis, and P.J. Conn Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function J. Neurosci. 21 2001 5925 5934
19. O.J. Manzoni, M.G. Weisskopf, and R.A. Nicoll MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus Eur. J. Neurosci. 6 1994 1050 1054
20. S. Otani, Y. Ben-Ari, and M.P. Roisin-Lallemand Metabotropic receptor stimulation coupled to weak tetanus leads to long-term potentiation and a rapid elevation of cytosolic protein kinase C activity Brain Res. 613 1993 1 9
21. G. Richter-Levin, M.L. Errington, H. Maegawa, and T.V. Bliss Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning Neuropharmacology 33 1994 853 857
22. G. Riedel, and K. Reymann An antagonist of the metabotropic glutamate receptor prevents LTP in the dentate gyrus of freely moving rats Neuropharmacology 32 1993 929 931
23. S.M. Rodrigues, E.P. Bauer, C.R. Farb, G.E. Schafe, and J.E. LeDoux The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala J. Neurosci. 22 2002 5219 5229
24. R. Rong, J.Y. Ahn, H. Huang, E. Nagata, D. Kalman, J.A. Kapp, J. Tu, P.F. Worley, S.H. Snyder, and K. Ye PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis Nat. Neurosci. 6 2003 1153 1161
25. P.P. Sanna, K.T. Keyser, T.J. Deerink, M.H. Ellisman, H.J. Karten, and F.E. Bloom Distribution and ontogeny of parvalbumin immunoreactivity in the chicken retina Neuroscience 47 1992 745 751
26. P.P. Sanna, F. Berton, M. Cammalleri, M.K. Tallent, G.R. Siggins, F.E. Bloom, and W. Francesconi A role for Src kinase in spontaneous epileptiform activity in the CA3 region of the hippocampus Proc. Natl. Acad. Sci. U. S. A. 97 2000 8653 8657
27. P.P. Sanna, M. Cammalleri, F. Berton, C. Simpson, R. Lutjens, F.E. Bloom, and W. Francesconi Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region J. Neurosci. 22 2002 3359 3365
28. R. Shigemoto, A. Kinoshita, E. Wada, S. Nomura, H. Ohishi, M. Takada, P.J. Flor, A. Neki, T. Abe, S. Nakanishi, and N. Mizuno Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus J. Neurosci. 17 1997 7503 7522
29. S.J. Tang, G. Reis, H. Kang, A.C. Gingras, N. Sonenberg, and E.M. Schuman A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus Proc. Natl. Acad. Sci. U. S. A. 99 2002 467 472
30. V.W. Wilsch, T. Behnisch, T. Jager, K.G. Reymann, and D. Balschun When are class I metabotropic glutamate receptors necessary for long-term potentiation? J. Neurosci. 18 1998 6071 6080