Methylphenidate administration determines enduring changes in neuroglial network in rats

European Neuropsychopharmacology

Volumn 22, Issue 1, 2012, Pages 53-63

  Cavaliere, Carlo ^a   Cirillo, Giovanni ^a   Bianco, Maria Rosaria ^a   Adriani, Walter ^b   De Simone, Antonietta ^a   Leo, Damiana ^c   Perrone Capano, Carla ^d,e   Papa, Michele ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

Author keywords

ADHD; Drug addiction; Glutamate transporters; Methylphenidate; NNOS; Plasticity; Reactive astrocytosis

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; METHYLPHENIDATE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTOSIS; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITIC SPINE; DRUG EFFECT; GLIA; LIMBIC CORTEX; MALE; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; CHOICE BEHAVIOR; CONDITIONING, OPERANT; GLIAL FIBRILLARY ACIDIC PROTEIN; METHYLPHENIDATE; NERVE NET; NEUROGLIA; NEURONS; NITRIC OXIDE SYNTHASE TYPE I; RATS; RATS, WISTAR; REWARD;

EID: 84155172488     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2011.04.003     Document Type: Article

References (60)

1. Adriani W., Rea M., Baviera M., Invernizzi W., Carli M., Ghirardi O., Caprioli A., Laviola G. Acetyl-L-carnitine reduces impulsive behaviour in adolescent rats. Psychopharmacology 2004, 176:296-304.
2. Adriani W., Leo D., Greco D., Rea M., di Porzio U., Laviola G., Perrone-Capano C. Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression. Neuropsychopharmacology 2006, 31:1946-1956.
3. Alvarez-Maubecin V., Garcia-Hernandez F., Williams J.T., Van Bockstaele E.J. Functional coupling between neurons and glia. J. Neurosci. 2000, 20:4091-4098.
4. Araque A., Parpura V., Sanzgiri R.P., Haydon P.G. Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci. 1999, 22:208-215.
5. Beique J.C. Homeostatic plasticity in a reward processing region: accumbens neurons scale too! (Commentary on Sun & Wolf). Eur. J. Neurosci. 2009, 30:537-538.
6. Berman S., O'Neill J., Fears S., Bartzokis G., London E.D. Abuse of amphetamines and structural abnormalities in the brain. Ann. N. Y. Acad. Sci. 2008, 1141:195-220.
7. Brahmachari S., Fung Y.K., Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J. Neurosci. 2006, 26:4930-4939.
8. Bunch L., Erichsen M.N., Jensen A.A. Excitatory amino acid transporters as potential drug targets. Expert Opin. Ther. Targets 2009, 13:719-731.
9. Carlezon W.A., Konradi C. Understanding the neurobiological consequences of early exposure to psychotropic drugs: linking behavior with molecules. Neuropharmacology 2004, 47:47-60.
10. Cavaliere C., Cirillo G., Bianco M.R., Rossi F., De Novellis V., Maione S., Papa M. Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model. Neuron Glia Biol. 2007, 3:141-153.
11. Cirillo G., Maggio N., Bianco M.R., Vollono C., Sellitti S., Papa M. Discriminative behavioral assessment unveils remarkable reactive astrocytosis and early molecular correlates in basal ganglia of 3-nitropropionic acid subchronic treated rats. Neurochem. Int. 2010, 56:152-160.
12. Eng L.F., Ghirnikar R.S. GFAP and astrogliosis. Brain Pathol. 1994, 4:229-237.
13. French S.J., Totterdell S. Quantification of morphological differences in boutons from different afferent populations to the nucleus accumbens. Brain Res. 2004, 1007:167-177.
14. Giaume C., Koulakoff A., Roux L., Holcman D., Rouach N. Astroglial networks: a step further in neuroglial and gliovascular interactions. Nat. Rev. Neurosci. 2010, 11:87-99.
15. Giovannoni R., Maggio N., Bianco M.R., Cavaliere C., Cirillo G., Lavitrano M., Papa M. Reactive astrocytosis and glial glutamate transporter clustering are early changes in a spinocerebellar ataxia type 1 transgenic mouse model. Neuron Glia Biol. 2007, 3:335-351.
16. Gray J.D., Punsoni M., Tabori N.E., Melton J.T., Fanslow V., Ward M.J., Zupan B., Menzer D., Rice J., Drake C.T., Romeo R.D., Brake W.G., Torres-Reveron A., Milner T.A. Methylphenidate administration to juvenile rats alters brain areas involved in cognition, motivated behaviors, appetite, and stress. J. Neurosci. 2007, 27:7196-7207.
17. Guilarte T.R., Nihei M.K., McGlothan J.L., Howard A.S. Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity. Neuroscience 2003, 122:499-513.
18. Hamilton N.B., Attwell D. Do astrocytes really exocytose neurotransmitters?. Nat. Rev. Neurosci. 2010, 11:227-238.
19. Hastjarjo T., Silberberg A., Hursh S.R. Risky choice as a function of amount and variance in food supply. J. Exp. Anal. Behav. 1990, 53:155-161.
20. Haydon P.G., Blendy J., Moss S.J., Rob Jackson F. Astrocytic control of synaptic transmission and plasticity: a target for drugs of abuse?. Neuropharmacology 2009, 56(Suppl. 1):83-90.
21. Henneberger C., Papouin T., Oliet S.H., Rusakov D.A. Long-term potentiation depends on release of D-serine from astrocytes. Nature 2010, 463:232-236.
22. Hernandez P.J., Kelley A.E. Cracking addiction the second time around: reconsolidation of drug-related memories. Neuron 2005, 47:772-775.
23. Hyman S.E., Malenka R.C., Nestler E.J. Neural mechanisms of addiction: the role of reward-related learning and memory. Annu. Rev. Neurosci. 2006, 29:565-598.
24. Itzhak Y., Ali S.F. Role of nitrergic system in behavioral and neurotoxic effects of amphetamine analogs. Pharmacol. Ther. 2006, 109:246-262.
25. Jiang J., Amara S.G. New views of glutamate transporter structure and function: advances and challenges. Neuropharmacology 2011, 60:172-181.
26. Kaminski B.J., Ator N.A. Behavioral and pharmacological variables affecting risky choice in rats. J. Exp. Anal. Behav. 2001, 75:275-297.
27. Karisson R.-M., Heilig M., Holmes A. Loss of glutamate transporter GLAST (EAAT1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and mGlu2/3 agonist. Biol. Psychiatry 2008, 64:810-814.
28. Kauer J.A., Malenka R.C. Synaptic plasticity and addiction. Nat. Rev. Neurosci. 2007, 8:844-858.
29. Kelley A.E. Memory and addiction: shared neural circuitry and molecular mechanisms. Neuron 2004, 44:161-179.
30. Kugler P., Schleyer V. Developmental expression of glutamate transporters and glutamate dehydrogenase in astrocytes of the postnatal rat hippocampus. Hippocampus 2004, 14:975-985.
31. Leo D., Adriani W., Cavaliere C., Cirillo G., Marco E.M., Romano E., di Porzio U., Papa M., Perrone-Capano C., Laviola G. Methylphenidate to adolescent rats drives enduring changes of accumbal Htr7 expression: implications for impulsive behavior and neuronal morphology. Genes Brain Behav. 2009, 8:356-368.
32. Lobsiger C.S., Cleveland D.W. Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease. Nat. Neurosci. 2007, 10:1355-1360.
33. Lyles J., Cadet J.L. Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms. Brain Res. Brain Res. Rev. 2003, 42:155-168.
34. Machado-Vieira R., Manji H.K., Zarate C.A. The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders. Neuroscientist 2009, 15:525-539.
35. Maragakis N.J., Rothstein J.D. Glutamate transporters: animal models to neurologic disease. Neurobiol. Dis. 2004, 15:461-473.
36. Marsteller D.A., Gerasimov M.R., Schiffer W.K., Geiger J.M., Barnett C.R., Borg J.S., Scott S., Ceccarelli J., Volkow N.D., Molina P.E., Alexoff D.L., Dewey S.L. Acute handling stress modulates methylphenidate-induced catecholamine overflow in the medial prefrontal cortex. Neuropsychopharmacology 2002, 27:163-170.
37. McClure S.M., Laibson D.I., Loewenstein H., Cohen J.D. Separate neural systems value immediate and delayed monetary rewards. Science 2004, 306:503-507.
38. Mobini S., Chiang T.J., Al-Ruwaitea A.S., Ho M.Y., Bradshaw C.M., Szabadi E. Effect of central 5-hydroxytryptamine depletion on inter-temporal choice: a quantitative analysis. Psychopharmacology 2000, 149:313-318.
39. Musholt K., Cirillo G., Cavaliere C., Rosaria B.M., Bock J., Helmeke C., Braun K., Papa M. Neonatal separation stress reduces glial fibrillary acidic protein- and S100beta immunoreactive astrocytes in the rat medial precentral cortex. Dev. Neurobiol. 2009, 69:203-211.
40. Narita M., Miyatake M., Narita M., Shibasaki M., Shindo K., Nakamura A., Kuzumaki N., Nagumo Y., Suzuki T. Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse. Neuropsychopharmacology 2006, 31:2476-2488.
41. Narita M., Suzuki M., Kuzumaki N., Miyatake M., Suzuki T. Implication of activated astrocytes in the development of drug dependence differences between methamphetamine and morphine. Ann. N. Y. Acad. Sci. 2008, 1141:96-104.
42. Nestler E.J. Is there a common molecular pathway for addiction?. Nat. Neurosci. 2005, 8:1445-1449.
43. Newman E.A. New roles for astrocytes: regulation of synaptic transmission. Trends Neurosci. 2003, 26:536-542.
44. 2+-dependent glutamate release from astrocytes: vesicular glutamate transporters and cytosolic glutamate levels. Glia 2009, 57:1296-1305.
45. Paxinos G., Watson C.R., Emson P.C. AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. J. Neurosci. Methods 1980, 3:129-149.
46. Pierce R.C., Kalivas P.W. A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Res. Brain Res. Rev. 1997, 25:192-216.
47. Rao S.D., Yin H.Z., Weiss J.H. Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. J. Neurosci. 2003, 23:2627-2633.
48. Reissner K.J., Kalivas P.W. Using glutamate homeostasis as a target for treating addictive disorders. Behav. Pharmacol. 2010, 21:514-522.
49. Ridderinkhof K.R., van der Wildenberg W.P.M., Segalowitz S.J., Carter C.S. Neurocognitive mechanisms of cognitive control: the role of prefrontal cortex in action selection, response inhibition, performance monitoring and reward-based learning. Brain Cogn. 2004, 56:129-140.
50. Robinson T.E., Kolb B. Structural plasticity associated with exposure to drugs of abuse. Neuropharmacology 2004, 47:33-46.
51. Rouach N., Koulakoff A., Abudara V., Willecke K., Giaume C. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 2008, 322:1551-1555.
52. Russell V.A., Oades R.D., Tannock R., Killeen P.R., Auerbach J.G., Johansen E.B., Sagvolden T. Response variability in Attention-Deficit/Hyperactivity Disorder: a neuronal and glial energetics hypothesis. Behav. Brain Funct. 2006, 2:30.
53. Schikorski T., Stevens C.F. Quantitative ultrastructural analysis of hippocampal excitatory synapses. J. Neurosci. 1997, 17:5858-5867.
54. Schousboe A., Sarup A., Bak L.K., Waagepetersen H.S., Larsson O.M. Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission. Neurochem. Int. 2004, 45:521-527.
55. Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?. Trends Pharmacol. Sci. 1998, 19:328-334.
56. Wolf M.E. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants. Prog. Neurobiol. 1998, 54:679-720.
57. Wolf M.E., Sun X., Mangiavacchi S., Chao S.Z. Psychomotor stimulants and neuronal plasticity. Neuropharmacology 2004, 47:61-79.
58. Zahm D.S., Brog J.S. On the significance of subterritories in the "accumbens" part of the rat ventral striatum. Neuroscience 1992, 50:751-767.
59. Zorrilla E.P. Multiparous species present problems (and possibilities) to developmentalists. Dev. Psychobiol. 1997, 30:141-150.
60. Zweifel L.S., Argilli E., Bonci Zweifel, Palmiter R.D. Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron 2008, 59:486-496.