Exploring the interaction between siRNA and the SMoC biomolecule transporters: Implications for small molecule-mediated delivery of siRNA

Chemical Biology and Drug Design

Volumn 79, Issue 1, 2012, Pages 9-21

  Gooding, Matt ^a   Tudzarova, Slavica ^a   Worthington, Roberta J ^b   Kingsbury, Sarah R ^a   Rebstock, Anne Sophie ^a   Dube, Henry ^a   Simone, Michela I ^c   Visintin, Cristina ^a   Lagos, Dimitris ^d,f   Quesada, Juan Manuel Funes ^d   Laman, Heike ^e   Boshoff, Chris ^d   Williams, Gareth H ^a   Stoeber, Kai ^a   Selwood, David L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f UNIVERSITY OF HULL   (United Kingdom)

Author keywords

Calorimetric techniques; Chemical biology; Molecular modeling; Nanotechnology (drug discovery); RNAi and antisense techniques

Indexed keywords

ANTENNAPEDIA PROTEIN; BIPHENYL DERIVATIVE; HOMEODOMAIN PROTEIN; LIPOFECTAMINE; SMALL INTERFERING RNA; SMALL MOLECULE TRANSPORT AGENT;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GRIGNARD REACTION; HUMAN; HUMAN CELL; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SUZUKI REACTION;

CELL CYCLE PROTEINS; CELL LINE; GUANIDINE; HUMANS; KINETICS; MICROSCOPY, CONFOCAL; MOLECULAR DYNAMICS SIMULATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SMALL MOLECULE LIBRARIES;

EID: 84155162418     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01249.x     Document Type: Article

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