Insight into the cellular uptake mechanism of a secondary amphipathic cell-penetrating peptide for siRNA delivery

Biochemistry

Volumn 49, Issue 16, 2010, Pages 3393-3402

  Konate, Karidia ^a   Crombez, Laurence ^a   Deshayes, Sébastien ^a   Decaffmeyer, Marc ^b   Thomas, Annick ^b   Brasseur, Robert ^b   Aldrian, Gudrun ^a   Heitz, Frederic ^a   Divita, Gilles ^a  

^a UNIV MONTPELLIER   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; CELL-PENETRATING PEPTIDE; CELLULAR MEMBRANES; CELLULAR UPTAKE; CLINICAL APPLICATION; CONFORMATIONAL TRANSITIONS; ELECTROSTATIC INTERACTIONS; HELICAL STRUCTURES; HYDROPHOBIC CONTACT; NANOPARTICLE SYSTEMS; PRIMARY CELLS; PROTEOGLYCANS; SIRNA DELIVERY; STABLE COMPLEXES; STRUCTURAL POLYMORPHISMS; SURFACE MEMBRANES;

BIOLOGICAL MEMBRANES; CELL CULTURE; CELL MEMBRANES; ELECTROSTATICS; MEMBRANES; PEPTIDES; PHOSPHOLIPIDS; RNA;

COMPLEXATION;

CELL PENETRATING PEPTIDE; HEPARAN SULFATE; PHOSPHOLIPID DERIVATIVE; PROTEIN CADY; PROTEOGLYCAN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ADSORPTION; ALPHA HELIX; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FLUORESCENCE SPECTROSCOPY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL LINE; CELL MEMBRANE; CIRCULAR DICHROISM; GLYCOSAMINOGLYCANS; LIPOSOMES; MICELLES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NORMAL DISTRIBUTION; OLIGORIBONUCLEOTIDES; PEPTIDES; PHOSPHOLIPIDS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RNA, SMALL INTERFERING;

EID: 77951225648     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901791x     Document Type: Article

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