Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: Reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus

Journal of Cellular Biochemistry

Volumn 113, Issue 1, 2012, Pages 49-60

  Dakeng, Sumana ^a,b   Duangmano, Suwit ^a   Jiratchariyakul, Weena ^a   U Pratya, Yaowalak ^c   Bögler, Oliver ^b   Patmasiriwat, Pimpicha ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Apoptosis; Breast cancer; Cucurbitacin b; Trichosanthes cucumerina Linn.; WNT signaling

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; CUCURBITACIN; CUCURBITACIN B; CYCLIN D1; GALECTIN 3; GLYCOGEN SYNTHASE KINASE 3BETA; LYMPHOID ENHANCER FACTOR 1; MYC PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; T CELL FACTOR PROTEIN; TRICHOSANTHES EXTRACT; UNCLASSIFIED DRUG; WNT PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; GENE TRANSLOCATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; TRICHOSANTHES; TRICHOSANTHES CUCUMERINA; WESTERN BLOTTING;

APOPTOSIS; BETA CATENIN; BREAST NEOPLASMS; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; FEMALE; GALECTIN 3; GLYCOGEN SYNTHASE KINASE 3; HUMANS; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-MYC; TCF TRANSCRIPTION FACTORS; TRICHOSANTHES; TRITERPENES; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84055222706     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23326     Document Type: Article

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