Antiproliferative effects of cucurbitacin B in breast cancer cells: Down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle

International Journal of Molecular Sciences

Volumn 11, Issue 12, 2010, Pages 5323-5338

  Duangmano, Suwit ^a   Dakeng, Sumana ^a   Jiratchariyakul, Weena ^a   Suksamrarn, Apichart ^b   Smith, Duncan R ^a   Patmasiriwat, Pimpicha ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b RAMKHAMHAENG UNIVERSITY   (Thailand)

Author keywords

Breast cancer; c Myc; Cucurbitacin B; Estrogen receptor; hTERT; Telomerase

Indexed keywords

CUCURBITACIN; CUCURBITACIN B; DIHYDROCUCURBITACIN B; ESTROGEN RECEPTOR; MYC PROTEIN; TELOMERASE; UNCLASSIFIED DRUG; MYC PROTEIN, HUMAN; TERT PROTEIN, HUMAN; TRITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; ONCOGENE C MYC; PROTEIN EXPRESSION; TERT GENE; TRICHOSANTHES; TRICHOSANTHES CUCUMERINA; BIOSYNTHESIS; BREAST NEOPLASMS; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

TRICHOSANTHES CUCUMERINA;

BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROTO-ONCOGENE PROTEINS C-MYC; TELOMERASE; TRICHOSANTHES; TRITERPENES;

EID: 78650985401     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms11125323     Document Type: Article

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