Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells

Cancer Letters

Volumn 182, Issue 1, 2002, Pages 83-92

  Yeo, Jun Kyu ^a   Cha, Soon Do ^a   Cho, Chi Heum ^a   Kim, Sang Pyo ^a   Cho, Jae We ^b   Baek, Won Ki ^a   Suh, Min Ho ^a   Kwon, Taeg Kyu ^a   Park, Jong Wook ^a   Suh, Seong Il ^a  

^a Keimyung University School of Medicine   (South Korea)

^b Seonam University   (South Korea)

Author keywords

Bax; Calpain; Caspase; Se methylselenocysteine

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INHIBITOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CALPAIN; CALPEPTIN; CASPASE 3; CASPASE INHIBITOR; CYSTEINE DERIVATIVE; DNA FRAGMENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHOLIPASE C; PROTEIN BAX; PROTEIN INHIBITOR; SE METHYLSELENOCYSTEINE; SURVIVIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALPAIN; CASPASES; CYSTEINE; CYTOCHROME C GROUP; ENZYME ACTIVATION; FEMALE; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; ORGANOSELENIUM COMPOUNDS; OVARIAN NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 18344367420     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00075-7     Document Type: Article

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