Transcriptomic analysis in diabetic nephropathy of streptozotocin-induced diabetic rats

International Journal of Molecular Sciences

Volumn 12, Issue 12, 2011, Pages 8431-8448

  Lomas Soria, Consuelo ^a   Ramos Gómez, Minerva ^a   Guevara Olvera, Lorenzo ^b   Guevara González, Ramón ^a   Torres Pacheco, Irineo ^a   Gallegos Corona, Marco A ^a   Reynoso Camacho, Rosalía ^a  

^a UNIVERSIDAD AUTÓNOMA DE QUERÉTARO   (Mexico)

^b DEPARTAMENTO DE INGENIERÍA QUÍMICA   (Mexico)

Author keywords

cDNA libraries; Diabetes mellitus; Diabetic nephropathy; Suppression subtractive hybridization

Indexed keywords

ALBUMIN; ARGINOSUCCINATE LYASE; BINDING PROTEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM SENSING RECEPTOR; COMPLEMENTARY DNA; CREATININE; EXTRACELLULAR CALCIUM SENSING RECEPTOR; FARNESYLTRANSFERASE BETA SUBUNIT; GAMMA GLUTAMYLTRANSFERASE; GAMMA GLUTAMYLTRANSPEPTIDASE 1; GLUCOSE; GLUTAMATE AMMONIA LIGASE; HELICASE DNA BINDING PROTEIN 8; INOSITOL POLYPHOSPHATE MULTIKINASE; INSULIN; LYASE; PEPTIDASE; PHOSPHOTRANSFERASE; PROTEIN; PROTEIN FARNESYLTRANSFERASE; PROTEIN KINASE; PROTEIN KINASE WNK1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; THREONINE PROTEIN KINASE; TRANSCRIPTION FACTOR; UBIQUITIN SPECIFIC PEPTIDASE 2; UNCLASSIFIED DRUG; UREA; TRANSCRIPTOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE GENE; CONTROLLED STUDY; CREATININE CLEARANCE; DIABETIC NEPHROPATHY; DNA LIBRARY; DOWN REGULATION; EXPRESSED SEQUENCE TAG; FLUID INTAKE; FOOD INTAKE; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENETIC SCREENING; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; KIDNEY; KIDNEY MASS; MALE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PROTEIN METABOLISM; PROTEIN URINE LEVEL; RAT; SEQUENCE HOMOLOGY; STREPTOZOCIN DIABETES; SUPPRESSION SUBTRACTIVE HYBRIDIZATION; UPREGULATION; UREA BLOOD LEVEL; URINE VOLUME; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GENETICS; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; MALE; RATS; RATS, WISTAR; TRANSCRIPTOME;

EID: 84055217637     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12128431     Document Type: Article

References (42)

1. Reutens, A.T.; Atkins, R.C. Epidemiology of diabetic nephropathy. Contrib. Nephrol. 2011, 170, 1-7.
2. Caramori, M.L.; Mauer, M. Diabetes and nephropathy. Curr. Opin. Nephrol. Hypertens. 2003, 12, 273-282.
3. Wada, J.; Sun, L.; Kanwar, Y.S. Discovery of genes related to diabetic nephropathy in various animal models by current techniques. Contrib. Nephrol. 2011, 169, 161-174.
4. Bonnefont-Rousselot, D.; Beaudeux, J.L.; Therond, P.; Peynet, J.; Legrand, A.; Delattre, J. Diabetes mellitus, oxidative stress and advanced glycation end products. Ann. Pharm. Fr. 2004, 62, 147-157.
5. Alexandraki, K.; Piperi, C.; Kalofoutis, C. Inflammatory process in type 2 diabetes: The role of cytokines. Ann. N. Y. Acad. Sci. 2006, 1084, 89-117.
6. Chow, F.Y.; Nikolic-Paterson, D.J.; Atkins, R.C.; Tesch, G.H. Macrophages in streptozotocin induced diabetic nephropathy: Potential role in renal fibrosis. Nephrol. Dial. Transplant. 2004, 19, 2987-2996.
7. Kanwar, Y.S.; Wada, J.; Sun, L.; Xie, P.; Wallner, E.I.; Chen, S.; Chugh, S.; Danesh, F.R. Diabetic nephropathy: Mechanisms of renal disease progression. Exp. Biol. Med. 2008, 233, 4-11.
8. Najafian, B.; Mauer, M. Progression of diabetic nephropathy in type 1 diabetic patients. Diab. Res. Clin. Pract. 2009, 83, 1-8.
9. Wolf, G. New insights into the pathophysiology of diabetic nephropathy: From hemodynamics to molecular pathology. Eur. J. Clin. Invest. 2004, 34, 785-796.
10. Schrijvers, B.F.; Vriese, A.N.; Flyvbjerg, A. From hyperglicemia to diabetic kidney disease: The role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. Endocr. Rev. 2004, 25, 971-1010.
11. Raptis, A.; Viberti, G. Pathogenesis of diabetic nephropathy. Exp. Clin. Endocrinol. Diab. 2001, 109, 424-437.
12. Luda, D.; Yun-fai, C.L.; Aaron, P.C.; Alex, C.; Fauzia, M.; Betty, H.; Sergey, L.; Konstantin, L.; Nadya, G.; Eugene, D.S.; Paul, D.S. Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc. Natl. Acad. Sci. USA 1996, 93, 6025-6030.
13. Young, E.C.; Soo, K.A.; Won, T.L.; Jong, E.L.; Seung, H.P.; Bang, B.Y.; Kyung, A.P. Soybeans ameliolate diabetic nephropathy in rats. Evid. Based Complement. Alternat. Med. 2010, 7, 433-440.
14. Wilson, G.L.; Leiter, E.H. Streptozotocin interactions with pancreatic beta cells and the induction of insulin-dependent diabetes. Curr. Top. Microbiol. Immunol. 1990, 156, 27-54.
15. O'Connor, A.S.; Schelling, J.R. Diabetes and the kidney. Am. J. Kidney Dis. 2005, 46, 766-773.
16. Akbarzadeh, A.; Norouzian, D.; Mehrabi, M.R.; Jamshidi, S.H.; Farhangi, A.; Verdi, A.A.; Mofidian, S.M.A.; Lame-Rad, B. Induction of diabetes by streptozotocin in rats. Indian J. Clin. Biochem. 2007, 22, 60-64.
17. Yamabe, N.; Yokozawa, T.; Oya, T.; Kim, M. Therapeutic potential of (-)-epigallocatechin 3-O-gallate on renal damage in diabetic nephropathy model rats. J. Pharmacol. Exp. Ther. 2006, 9, 228-236.
18. Dalla, V.M.; Saller, A.; Bortoloso, E.; Mauer, M.; Fioretto, P. Structural involvement in type 1 and type 2 diabetic nephropathy. Diabetes Metab. 2000, 26, 8-14.
19. Omotayo, O.E.; Siti, A.S.; Mohd, S.A.W.; Sirajudeen, K.N.S.; Md, S.M.S.; Sunil, G. Comparison of antioxidant effects of honey, gliblenclamide, metmorfin, and their combinations in the kidneys of streptozotocin-induced diabetic rats. Int. J. Mol. Sci. 2011, 12, 829-843.
20. Singh, D.K.; Farrington, K. The tubulointerstitium in early diabetic nephropathy: Prime target or bystander. Int. J. Diabetes Dev. Ctry. 2010, 30, 185-190.
21. Funk, J.A.; Odejinmi, S.; Schnellmann, R.G. SRT1720 induces mitochondrial biogenesis and rescues mitochondrial function after oxidant injury in renal proximal tubule cells. J. Pharmacol. Exp. Ther. 2010, 333, 593-601.
22. Ceballos, I.; Chauveau, P.; Guerin, V.; Bardet, J.; Parvy, P.; Kamoun, P.; Jungers, P. Early alterations of plasma free amino acids in chronic renal failure. Clin. Chim. Acta 1990, 188, 101-108.
23. Chen, G.F.; Baylis, C. In vivo renal arginine release is impaired throughout development of chronic kidney disease. Am. J. Physiol. Renal Physiol. 2010, 298, 95-102.
24. McCormick, J.A.; Ellison, D.H. The WNKs: Atypical protein kinases with pleiotropic actions. Physiol. Rev. 2011, 91, 177-219.
25. + homeostasis by kidney-specific WNK1 kinase. J. Biol. Chem. 2009, 284, 12198-12206.
26. Li, S.; Wu, P.; Yarlagadda, P.; Vadjunec, N.M.; Proia, A.D.; Harris, R.A.; Portilla, D. PPAR alpha ligand protects during cisplatin-induced acute renal failure by preventing inhibition of renal FAO and PDC activity. Am. J. Physiol. Renal Physiol. 2004, 286, 572-580.
27. Cutrín, J.C.; Zingaro, B.; Camandola, S.; Boveris, A.; Pompella, A.; Poli, G. Contribution of gamma glutamyl transpeptidase to oxidative damage of ischemic rat kidney. Kidney Int. 2000, 57, 526-533.
28. Agnès, C.; Ola, K.; Hélène, D.; Michelle, B.; Mireille, M.; Bernard, F.; Gabriel, B. Inhibition of glutamine synthetase in the mouse kidney. J. Biol. Chem. 2003, 40, 38159-38166.
29. Lemieux, G.; Baverel, G.; Vinay, P.; Wadoux, P. Glutamine synthetase and glutamyltransferase in the kidney of man, dog, and rat. Am. J. Physiol. 1976, 4, 1068-1073.
30. Geibel, J.P. The calcium-sensing receptor. J. Nephrol. 2010, 16, 130-135.
31. Mathias, R.S.; Nguyen, H.T.; Zhang, M.Y.; Portale, A.A. Reduced expression of the renal calcium-sensing receptor in rats with experimental chronic renal insufficiency. J. Am. Soc. Nephrol. 1998, 9, 2067-2074.
32. Targos, B.; Barańska, J.; Pomorski, P. Store-operated calcium entry in physiology and pathology of mammalian cells. Acta Biochim. Pol. 2005, 52, 397-409.
33. 2+/calmodulin-dependent protein kinase II stimulates c-fos transcription and DNA synthesis by a Src-based mechanism in glomerular mesangial cells. J. Am. Soc. Nephrol. 2003, 14, 28-36.
34. Michalik, L.; Desvergne, B.; Wahli, W. Peroxisome proliferator-activated receptors and cancers: Complex stories. Nat. Rev. Cancer 2004, 4, 61-70.
35. Hao, C.M.; Redha, R.; Morrow, J.; Breyer, M.D. Peroxisome proliferator-activated receptor delta activation promotes cell survival following hypertonic stress. J. Biol. Chem. 2001, 277, 21341-21345.
36. Yang, T.; Michelle, D.E.; Park, J.; Smart, A.M.; Lin, Z.; Brosius, F.C.; Schnermann, J.B.; Briggs, J.P. Expression of peroxisomal proliferator-activated receptors and retinoid X receptors in the kidney. Am. J. Physiol. Renal Physiol. 1999, 277, 966-973.
37. Letavernier, E.; Perez, J.; Joye, E.; Bellocq, A.; Fouqueray, B.; Haymann, J.P.; Heudes, D.; Wahli, W.; Desvergne, B.; Baud, L. Peroxisome proliferator-activated receptor β/δ exerts a strong protection from ischemic acute renal failure. J. Am. Soc. Nephrol. 2005, 16, 2395-2402.
38. Chmielewski, M.; Sucajtys-Szulc, E.; Kossowska, E.; Swierczynski, J.; Rutkowski, B.; Boguslawski, W. Increased gene expression of liver SREBP-2 in experimental chronic renal failure. Atherosclerosis 2007, 191, 326-332.
39. Szolkiewicz, M.; Chmielewski, M.; Nogalska, A.; Stelmanska, E.; Swierczynski, J.; Rutkowski, B. The potential role of sterol regulatory element binding protein transcription factors in renal injury. J. Ren. Nutr. 2007, 17, 62-65.
40. Tao, J.; Scott, E.L.; Scott, L.; Jinping, L.; Moshe, L. Role of altered renal lipid metabolism and the sterol regulatory element binding proteins in the pathogenesis of age-related renal disease. Kidney Int. 2005, 68, 2608-2620.
41. Altschul, S.F.; Gish, W.; Miller, W.; Myers, E.W.; Lipman, D.J. Basic local alignment search tool. J. Mol. Biol. 1990, 215, 403-410.
42. Santos, L.; León-Galván, M.F.; Marino-Marmolejo, E.N.; Barba de la Rosa, A.P.; de León Rodríguez, A.; González-Amaro, R.; Guevara-González, R.G. Identification of differential expressed transcripts in cervical cancer of Mexican patients. Tumor Biol. 2011, 32, 561-568.