Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation

Journal of Pharmaceutical and Biomedical Analysis

Volumn 60, Issue , 2012, Pages 51-58

  Pauwels, Jochen ^a   D'Autry, Ward ^a   Van den Bossche, Larissa ^a   Dewever, Cédric ^a   Forier, Michel ^a   Vandenwaeyenberg, Stephanie ^a   Wolfs, Kris ^a   Hoogmartens, Jos ^a   Van Schepdael, Ann ^a   Adams, Erwin ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Gas chromatography; Headspace sampling; Liquid chromatography; Topical formulation

Indexed keywords

CAMPHOR; CAPSAICIN DERIVATIVE; GLYCOL SALICYLATE; MENTHOL; SALICYLIC ACID; SALICYLIC ACID DERIVATIVE; SALICYLIC ACID ETHYL ESTER; SALICYLIC ACID METHYL ESTER; TOPICAL AGENT; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; OINTMENT; PRIORITY JOURNAL; PROCESS OPTIMIZATION; STATIC HEADSPACE GAS CHROMATOGRAPHY; VALIDATION STUDY;

ANALGESICS, NON-NARCOTIC; CAMPHOR; CAPSAICIN; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, LIQUID; LIQUID-LIQUID EXTRACTION; MENTHOL; OINTMENTS; PHARMACEUTICAL PREPARATIONS; SALICYLATES; SALICYLIC ACID; SENSITIVITY AND SPECIFICITY;

EID: 83955162309     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.10.024     Document Type: Article

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