Ectopic retinoic acid signaling affects outflow tract cushion development through suppression of the myocardial Tbx2-Tgfβ2 pathway

Development

Volumn 139, Issue 2, 2012, Pages 385-395

  Sakabe, Masahide ^a,b   Kokubo, Hiroki ^a   Nakajima, Yuji ^c   Saga, Yumiko ^a  

^a NATIONAL INSTITUTE OF GENETICS   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Endocardial cushion tissue; Mouse; Retinoic acid signaling; Tbx2; TGA

Indexed keywords

PROTEIN; PROTEIN TBX2; RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; EMBRYO; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEART VENTRICLE SEPTUM DEFECT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION INITIATION;

ANIMALS; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ENDOCARDIAL CUSHION DEFECTS; FEMALE; GALACTOSIDES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDOLES; LUCIFERASES; MATERNAL-FETAL EXCHANGE; MICE; MICROARRAY ANALYSIS; MYOCARDIUM; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TRANSFORMING GROWTH FACTOR BETA2; TRETINOIN;

EID: 83755220982     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.067058     Document Type: Article

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