T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfβ2 expression and endocardial cushion formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 44, 2009, Pages 18604-18609

  Shirai, Manabu ^a   Imanaka Yoshida, Kyoko ^b   Schneider, Michael D ^c   Schwartz, Robert J ^d   Morisaki, Takayuki ^e  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Cardiac jelly; Cardiomyocyte identity; Epithelial mesenchymal transformation; Extracellular matrix; Misexpression

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; CRE RECOMBINASE; HYALURONAN SYNTHASE 2; SMAD PROTEIN; SYNTHETASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBX2; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOCARDIAL CUSHION; GENE ACTIVITY; GENE TARGETING; HEART DEVELOPMENT; LOXP SITE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; ENDOCARDIAL CUSHIONS; ENHANCER ELEMENTS, GENETIC; ENZYME INDUCTION; EPITHELIUM; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCURONOSYLTRANSFERASE; MESODERM; MICE; MODELS, BIOLOGICAL; MORPHOGENESIS; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION; SMAD PROTEINS; T-BOX DOMAIN PROTEINS; TRANSFORMING GROWTH FACTOR BETA2; TRANSGENES;

EID: 73249139527     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0900635106     Document Type: Article

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