Reduced light response of neuronal firing activity in the suprachiasmatic nucleus and optic nerve of cryptochrome-deficient mice

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Nakamura, Takahiro J ^a,b,c   Ebihara, Shizufumi ^b   Shinohara, Kazuyuki ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c TEIKYO HEISEI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOCHROME; CRYPTOCHROME 1; CRYPTOCHROME 2;

ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; COSMOLOGICAL PHENOMENA; DAYTIME; FUNCTIONS OF THE SENSE ORGANS AND THE SENSORY NERVOUS SYSTEM; GENOTYPE; ILLUMINATION; IN VIVO STUDY; KNOCKOUT MOUSE; LIGHT; MALE; MOUSE; NERVE CELL MEMBRANE POTENTIAL; NIGHT; NONHUMAN; OPTIC NERVE; OPTIC NERVE FIBER; PHOTORECEPTION; PHOTOSTIMULATION; RETINA; SINGLE UNIT ACTIVITY; SUPRACHIASMATIC NUCLEUS; WILD TYPE; ANIMAL; CYTOLOGY; GENETICS; MICROELECTRODE; MOUSE MUTANT; NERVE CELL; PHYSIOLOGY;

ANIMALS; CRYPTOCHROMES; LIGHT; MALE; MICE; MICE, KNOCKOUT; MICROELECTRODES; NEURONS; OPTIC NERVE; SUPRACHIASMATIC NUCLEUS;

EID: 83755220917     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028726     Document Type: Article

References (44)

1. Inouye ST, Shibata S, (1994) Neurochemical organization of circadian rhythm in the suprachiasmatic nucleus. Neurosci Res 20: 109-130.
2. Lowrey PL, Takahashi JS, (2000) Genetics of the mammalian circadian system: Photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation. Annu Rev Genet 34: 533-562.
3. Freedman MS, Lucas RJ, Soni B, von Schantz M, Munoz M, et al. (1999) Regulation of mammalian circadian behavior by non-rod, non-cone, ocular photoreceptors. Science 284: 502-504.
4. Mrosovsky N, Foster RG, Salmon PA, (1999) Thresholds for masking responses to light in three strains of retinally degenerate mice. J Comp Physiol [A] 184: 423-428.
5. Lucas RJ, Freedman MS, Munoz M, Garcia-Fernandez JM, Foster RG, (1999) Regulation of the mammalian pineal by non-rod, non-cone, ocular photoreceptors. Science 284: 505-507.
6. Lucas RJ, Douglas RH, Foster RG, (2001) Characterization of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci 4: 621-626.
7. Provencio I, Rodriguez IR, Jiang G, Hayes WP, Moreira EF, et al. (2000) A novel human opsin in the inner retina. J Neurosci 20: 600-605.
8. Miyamoto Y, Sancar A, (1998) Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals. Proc Natl Acad Sci U S A 95: 6097-6102.
9. Bowes C, Li T, Danciger M, Baxter LC, Applebury ML, et al. (1990) Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase. Nature 347: 677-680.
10. Carter-Dawson LD, LaVail MM, Sidman RL, (1978) Differential effect of the rd mutation on rods and cones in the mouse retina. Invest Ophthalmol Vis Sci 17: 489-498.
11. Yoshimura T, Ebihara S, (1998) Decline of circadian photosensitivity associated with retinal degeneration in CBA/J-rd/rd mice. Brain Res 779: 188-193.
12. Panda S, Sato TK, Castrucci AM, Rollag MD, DeGrip WJ, et al. (2002) Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 298: 2213-2216.
13. Ruby NF, Brennan TJ, Xie X, Cao V, Franken P, et al. (2002) Role of melanopsin in circadian responses to light. Science 298: 2211-2213.
14. Lucas RJ, Hattar S, Takao M, Berson DM, Foster RG, et al. (2003) Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice. Science 299: 245-247.
15. Panda S, Provencio I, Tu DC, Pires SS, Rollag MD, et al. (2003) Melanopsin is required for non-image-forming photic responses in blind mice. Science 301: 525-527.
16. Hattar S, Lucas RJ, Mrosovsky N, Thompson S, Douglas RH, et al. (2003) Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature 424: 76-81.
17. Sancar A, (2000) Cryptochrome: the second photoactive pigment in the eye and its role in circadian photoreception. Annu Rev Biochem 69: 31-67.
18. Miyamoto Y, Sancar A, (1999) Circadian regulation of cryptochrome genes in the mouse. Brain Res Mol Brain Res 71: 238-243.
19. Selby CP, Thompson C, Schmitz TM, Van Gelder RN, Sancar A, (2000) Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice. Proc Natl Acad Sci U S A 97: 14697-14702.
20. Vitaterna MH, Selby CP, Todo T, Niwa H, Thompson C, et al. (1999) Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2. Proc Natl Acad Sci U S A 96: 12114-12119.
21. Van Gelder RN, Wee R, Lee JA, Tu DC, (2003) Reduced pupillary light responses in mice lacking cryptochromes. Science 299: 222.
22. Mrosovsky N, (2001) Further characterization of the phenotype of mCry1/mCry2-deficient mice. Chronobiol Int 18: 613-625.
23. Van Gelder RN, Gibler TM, Tu D, Embry K, Selby CP, et al. (2002) Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms. J Neurogenet 16: 181-203.
24. van der Horst GT, Muijtjens M, Kobayashi K, Takano R, Kanno S, et al. (1999) Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. Nature 398: 627-630.
25. Meijer JH, Groos GA, Rusak B, (1986) Luminance coding in a circadian pacemaker: the suprachiasmatic nucleus of the rat and the hamster. Brain Res 382: 109-118.
26. Meijer JH, Rusak B, Ganshirt G, (1992) The relation between light-induced discharge in the suprachiasmatic nucleus and phase shifts of hamster circadian rhythms. Brain Res 598: 257-263.
27. Meijer JH, Watanabe K, Schaap J, Albus H, Detari L, (1998) Light responsiveness of the suprachiasmatic nucleus: long-term multiunit and single-unit recordings in freely moving rats. J Neurosci 18: 9078-9087.
28. Nakamura TJ, Fujimura K, Ebihara S, Shinohara K, (2004) Light response of the neuronal firing activity in the suprachiasmatic nucleus of mice. Neurosci Lett 371: 244-248.
29. Hartline HK, (1938) The response of single optic nerve fibers of the vertebrate eye to illumination of the retina. Am J Physiol 121: 400-415.
30. Bisti S, Gargini C, Chalupa LM, (1998) Blockade of glutamate-mediated activity in the developing retina perturbs the functional segregation of ON and OFF pathways. J Neurosci 18: 5019-5025.
31. Wang GY, Liets LC, Chalupa LM, (2001) Unique functional properties of on and off pathways in the developing mammalian retina. J Neurosci 21: 4310-4317.
32. Thompson CL, Selby CP, Partch CL, Plante DT, Thresher RJ, et al. (2004) Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction. Brain Res Mol Brain Res 122: 158-166.
33. Albus H, Bonnefont X, Chaves I, Yasui A, Doczy J, et al. (2002) Cryptochrome-deficient mice lack circadian electrical activity in the suprachiasmatic nuclei. Curr Biol 12: 1130-1133.
34. Block GD, Khalsa SB, McMahon DG, Michel S, Guesz M, (1993) Biological clocks in the retina: cellular mechanisms of biological timekeeping. Int Rev Cytol 146: 83-144.
35. Barlow RB Jr, Bolanowski SJ Jr, Brachman ML, (1977) Efferent optic nerve fibers mediate circadian rhythms in the Limulus eye. Science 197: 86-89.
36. LaVail MM, Ward PA, (1978) Studies on the hormonal control of circadian outer segment disc shedding in the rat retina. Invest Ophthalmol Vis Sci 17: 1189-1183.
37. Terman M, Terman J, (1985) A circadian pacemaker for visual sensitivity? Ann N Y Acad Sci 453: 147-161.
38. Bassi CJ, Powers MK, (1986) Daily fluctuations in the detectability of dim lights by humans. Physiol Behav 38: 871-877.
39. Berson DM, Dunn FA, Takao M, (2002) Phototransduction by retinal ganglion cells that set the circadian clock. Science 295: 1070-1073.
40. Berson DM, (2003) Strange vision: ganglion cells as circadian photoreceptors. Trends Neurosci 26: 314-320.
41. Hattar S, Liao HW, Takao M, Berson DM, Yau KW, (2002) Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science 295: 1065-1070.
42. Green CB, Besharse JC, (2004) Retinal circadian clocks and control of retinal physiology. J Biol Rhythms 19: 91-102.
43. Ruan GX, Zhang DQ, Zhou T, Yamazaki S, McMahon DG, (2006) Circadian organization of the mammalian retina. Proc Natl Acad Sci U S A 103: 9703-9708.
44. Baba K, Sengupta A, Tosini M, Contreras-Alcantara S, Tosini G, Circadian regulation of the PERIOD 2::LUCIFERASE bioluminescence rhythm in the mouse retinal pigment epithelium-choroid. Mol Vis 16: 2605-2611.