메뉴 건너뛰기




Volumn 108, Issue 49, 2011, Pages 19617-19622

Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2

Author keywords

[No Author keywords available]

Indexed keywords

ACID LIPASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PHOSPHATIDIC ACID; PHOSPHOLIPASE D2; RAC2 PROTEIN;

EID: 83755207388     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114692108     Document Type: Article
Times cited : (43)

References (34)
  • 1
    • 33750610850 scopus 로고    scopus 로고
    • Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis
    • Pestonjamasp KN, et al. (2006) Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis. Blood 108:2814-2820.
    • (2006) Blood , vol.108 , pp. 2814-2820
    • Pestonjamasp, K.N.1
  • 2
    • 70350070478 scopus 로고    scopus 로고
    • Large Arf1 guanine nucleotide exchange factors: Evolution, domain structure, and roles in membrane trafficking and human disease
    • Bui QT, Golinelli-Cohen MP, Jackson CL (2009) Large Arf1 guanine nucleotide exchange factors: Evolution, domain structure, and roles in membrane trafficking and human disease. Mol Genet Genomics 282:329-350.
    • (2009) Mol Genet Genomics , vol.282 , pp. 329-350
    • Bui, Q.T.1    Golinelli-Cohen, M.P.2    Jackson, C.L.3
  • 3
    • 22744445886 scopus 로고    scopus 로고
    • Signaling interplay in ras superfamily function
    • DOI 10.1016/j.cub.2005.07.010, PII S0960982205007487
    • Mitin N, Rossman KL, Der CJ (2005) Signaling interplay in Ras superfamily function. Curr Biol 15:R563-R574. (Pubitemid 41026614)
    • (2005) Current Biology , vol.15 , Issue.14
    • Mitin, N.1    Rossman, K.L.2    Der, C.J.3
  • 4
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
    • DOI 10.1038/nrm1587
    • Rossman KL, Der CJ, Sondek J (2005) GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6(2):167-180. (Pubitemid 40215811)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.2 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 7
    • 55549089615 scopus 로고    scopus 로고
    • Large ARF guanine nucleotide exchange factors in membrane trafficking
    • Anders N, Jürgens G (2008) Large ARF guanine nucleotide exchange factors in membrane trafficking. Cell Mol Life Sci 65:3433-3445.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3433-3445
    • Anders, N.1    Jürgens, G.2
  • 8
    • 33646866944 scopus 로고    scopus 로고
    • The elucidation of novel SH2 binding sites on PLD2
    • DOI 10.1038/sj.onc.1209340, PII 1209340
    • Di Fulvio M, Lehman N, Lin X, Lopez I, Gomez-Cambronero J (2006) The elucidation of novel SH2 binding sites on PLD2. Oncogene 25:3032-3040. (Pubitemid 43780467)
    • (2006) Oncogene , vol.25 , Issue.21 , pp. 3032-3040
    • Di, F.M.1    Lehman, N.2    Lin, X.3    Lopez, I.4    Gomez-Cambronero, J.5
  • 9
    • 34447568476 scopus 로고    scopus 로고
    • Phospholipase D2- Generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos
    • Zhao C, Du G, Skowronek K, Frohman MA, Bar-Sagi D (2007) Phospholipase D2- generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. Nat Cell Biol 9:706-712.
    • (2007) Nat Cell Biol , vol.9 , pp. 706-712
    • Zhao, C.1    Du, G.2    Skowronek, K.3    Frohman, M.A.4    Bar-Sagi, D.5
  • 10
    • 79955546947 scopus 로고    scopus 로고
    • Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2
    • Peng HJ, Henkels KM, Mahankali M, Dinauer MC, Gomez-Cambronero J (2011) Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2. J Biol Chem 286:16308-16320.
    • (2011) J Biol Chem , vol.286 , pp. 16308-16320
    • Peng, H.J.1    Henkels, K.M.2    Mahankali, M.3    Dinauer, M.C.4    Gomez-Cambronero, J.5
  • 11
    • 0026044409 scopus 로고
    • Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product
    • Hart MJ, Eva A, Evans T, Aaronson SA, Cerione RA (1991) Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature 354:311-314. (Pubitemid 21896884)
    • (1991) Nature , vol.354 , Issue.6351 , pp. 311-314
    • Hart, M.J.1    Eva, A.2    Evans, T.3    Aaronson, S.A.4    Cerione, R.A.5
  • 12
    • 32144455201 scopus 로고    scopus 로고
    • In vitro guanine nucleotide exchange activity of DHR-2/ DOCKER/CZH2 domains
    • Côté JF, Vuori K (2006) In vitro guanine nucleotide exchange activity of DHR-2/ DOCKER/CZH2 domains. Methods Enzymol 406:41-57.
    • (2006) Methods Enzymol , vol.406 , pp. 41-57
    • Côté, J.F.1    Vuori, K.2
  • 13
    • 0025277948 scopus 로고
    • A cytosolic protein catalyzes the release of GDP from p21ras
    • Wolfman A, Macara IG (1990) A cytosolic protein catalyzes the release of GDP from p21ras. Science 248(4951):67-69.
    • (1990) Science , vol.248 , Issue.4951 , pp. 67-69
    • Wolfman, A.1    Macara, I.G.2
  • 14
    • 0025186360 scopus 로고
    • Purification of a factor capable of stimulating the guanine nucleotide exchange reaction of ras proteins and its effect on ras-related small molecular mass G proteins
    • Huang YK, Kung HF, Kamata T (1990) Purification of a factor capable of stimulating the guanine nucleotide exchange reaction of ras proteins and its effect on ras-related small molecular mass G proteins. Proc Natl Acad Sci USA 87:8008-8012.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8008-8012
    • Huang, Y.K.1    Kung, H.F.2    Kamata, T.3
  • 15
    • 0025043199 scopus 로고
    • Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins
    • Yamamoto T, et al. (1990) Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins. J Biol Chem 265:16626-16634.
    • (1990) J Biol Chem , vol.265 , pp. 16626-16634
    • Yamamoto, T.1
  • 16
    • 33845751023 scopus 로고    scopus 로고
    • phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity
    • DOI 10.1128/MCB.00985-06
    • Ming W, Li S, Billadeau DD, Quilliam LA, Dinauer MC (2007) The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. Mol Cell Biol 27:312-323. (Pubitemid 46013253)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.1 , pp. 312-323
    • Ming, W.1    Li, S.2    Billadeau, D.D.3    Quilliam, L.A.4    Dinauer, M.C.5
  • 17
    • 0027729274 scopus 로고
    • Regulation of phagocyte function by low molecular weight GTPbinding proteins
    • Bokoch GM (1993) Regulation of phagocyte function by low molecular weight GTPbinding proteins. Eur J Haematol 51:313-317.
    • (1993) Eur J Haematol , vol.51 , pp. 313-317
    • Bokoch, G.M.1
  • 18
    • 0028081350 scopus 로고
    • Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins
    • Bokoch GM, Bohl BP, Chuang TH (1994) Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. J Biol Chem 269:31674-31679. (Pubitemid 24379533)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.50 , pp. 31674-31679
    • Bokoch, G.M.1    Bohl, B.P.2    Chuang, T.-H.3
  • 19
    • 33750924781 scopus 로고    scopus 로고
    • Regulation of the phagocyte NADPH oxidase by Rac GTPase
    • DOI 10.1089/ars.2006.8.1533
    • Bokoch GM, Zhao T (2006) Regulation of the phagocyte NADPH oxidase by Rac GTPase. Antioxid Redox Signal 8:1533-1548. (Pubitemid 44726329)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.9-10 , pp. 1533-1548
    • Bokoch, G.M.1    Zhao, T.2
  • 20
    • 33751175188 scopus 로고    scopus 로고
    • Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2
    • Lehman N, et al. (2006) Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2. Blood 108:3564-3572.
    • (2006) Blood , vol.108 , pp. 3564-3572
    • Lehman, N.1
  • 21
    • 0346996709 scopus 로고    scopus 로고
    • Granulocyte-Macrophage Colony-Stimulating Factor Is a Chemoattractant Cytokine for Human Neutrophils: Involvement of the Ribosomal p70 S6 Kinase Signaling Pathway
    • Gomez-Cambronero J, Horn J, Paul CC, Baumann MA (2003) Granulocyte-macrophage colony-stimulating factor is a chemoattractant cytokine for human neutrophils: Involvement of the ribosomal p70 S6 kinase signaling pathway. J Immunol 171:6846-6855. (Pubitemid 37532120)
    • (2003) Journal of Immunology , vol.171 , Issue.12 , pp. 6846-6855
    • Gomez-Cambronero, J.1    Horn, J.2    Paul, C.C.3    Baumann, M.A.4
  • 22
    • 79958047890 scopus 로고    scopus 로고
    • The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis
    • Peng HJ, et al. (2011) The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis. Mol Cell Biol 31:2227-2240.
    • (2011) Mol Cell Biol , vol.31 , pp. 2227-2240
    • Peng, H.J.1
  • 23
    • 0036045768 scopus 로고    scopus 로고
    • Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
    • Brugnera E, et al. (2002) Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol 4:574-582.
    • (2002) Nat Cell Biol , vol.4 , pp. 574-582
    • Brugnera, E.1
  • 24
    • 0037086652 scopus 로고    scopus 로고
    • A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange
    • DOI 10.1093/emboj/21.6.1315
    • Rossman KL, et al. (2002) A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J 21:1315-1326. (Pubitemid 34246510)
    • (2002) EMBO Journal , vol.21 , Issue.6 , pp. 1315-1326
    • Rossman, K.L.1    Worthylake, D.K.2    Snyder, J.T.3    Siderovski, D.P.4    Campbell, S.L.5    Sondek, J.6
  • 25
    • 68949149746 scopus 로고    scopus 로고
    • Phosphatidic acid signaling regulation of Ras superfamily of small guanosine triphosphatases
    • Zhang Y, Du G (2009) Phosphatidic acid signaling regulation of Ras superfamily of small guanosine triphosphatases. Biochim Biophys Acta 1791:850-855.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 850-855
    • Zhang, Y.1    Du, G.2
  • 26
    • 33746896166 scopus 로고    scopus 로고
    • The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis
    • Suh CI, et al. (2006) The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med 203:1915-1925.
    • (2006) J Exp Med , vol.203 , pp. 1915-1925
    • Suh, C.I.1
  • 27
    • 3142654859 scopus 로고    scopus 로고
    • Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species
    • DOI 10.1074/jbc.M313891200
    • Diebold BA, Fowler B, Lu J, Dinauer MC, Bokoch GM (2004) Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. J Biol Chem 279:28136-28142. (Pubitemid 38900087)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.27 , pp. 28136-28142
    • Diebold, B.A.1    Fowler, B.2    Lu, J.3    Dinauer, M.C.4    Bokoch, G.M.5
  • 28
    • 0037183494 scopus 로고    scopus 로고
    • Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase
    • DOI 10.1021/bi0257033
    • Moskwa P, Dagher MC, Paclet MH, Morel F, Ligeti E (2002) Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase. Biochemistry 41:10710-10716. (Pubitemid 34913331)
    • (2002) Biochemistry , vol.41 , Issue.34 , pp. 10710-10716
    • Moskwa, P.1    Dagher, M.-C.2    Paclet, M.-H.3    Morel, F.4    Ligeti, E.5
  • 30
    • 65249117435 scopus 로고    scopus 로고
    • Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis
    • Nishikimi A, et al. (2009) Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science 324:384-387.
    • (2009) Science , vol.324 , pp. 384-387
    • Nishikimi, A.1
  • 32
    • 32144432437 scopus 로고    scopus 로고
    • The SWISS-MODEL workspace: A web-based environment for protein structure homology modelling
    • DOI 10.1093/bioinformatics/bti770
    • Arnold K, Bordoli L, Kopp J, Schwede T (2006) The SWISS-MODEL workspace: A webbased environment for protein structure homology modelling. Bioinformatics 22:195-201. (Pubitemid 43205406)
    • (2006) Bioinformatics , vol.22 , Issue.2 , pp. 195-201
    • Arnold, K.1    Bordoli, L.2    Kopp, J.3    Schwede, T.4
  • 33
    • 0042622380 scopus 로고    scopus 로고
    • SWISS-MODEL: An automated protein homology-modeling server
    • DOI 10.1093/nar/gkg520
    • Schwede T, Kopp J, Guex N, Peitsch MC (2003) SWISS-MODEL: An automated protein homology-modeling server. Nucleic Acids Res 31:3381-3385. (Pubitemid 37442164)
    • (2003) Nucleic Acids Research , vol.31 , Issue.13 , pp. 3381-3385
    • Schwede, T.1    Kopp, J.2    Guex, N.3    Peitsch, M.C.4
  • 34
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
    • DOI 10.1002/elps.1150181505
    • Guex N, Peitsch MC (1997) SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling. Electrophoresis 18:2714-2723. (Pubitemid 28059943)
    • (1997) Electrophoresis , vol.18 , Issue.15 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.