-
1
-
-
34249337761
-
Perceptions of epigenetics
-
Bird, A. 2007. Perceptions of epigenetics. Nature 447: 396-398.
-
(2007)
Nature
, vol.447
, pp. 396-398
-
-
Bird, A.1
-
2
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski, A. et al. 2007. High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
-
3
-
-
40749109894
-
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
-
Cokus, S.J. et al. 2008. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 452: 215-219.
-
(2008)
Nature
, vol.452
, pp. 215-219
-
-
Cokus, S.J.1
-
4
-
-
84957846754
-
The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography
-
Hotchkiss, R.D. 1948. The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J. Biol. Chem. 175: 315-332.
-
(1948)
J. Biol. Chem.
, vol.175
, pp. 315-332
-
-
Hotchkiss, R.D.1
-
5
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch, R. & A. Bird. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33(Suppl): 245-254.
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
6
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
Feinberg, A.P. 2007. Phenotypic plasticity and the epigenetics of human disease. Nature 447: 433-440.
-
(2007)
Nature
, vol.447
, pp. 433-440
-
-
Feinberg, A.P.1
-
7
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg, A.P. & B. Tycko. 2004. The history of cancer epigenetics. Nat. Rev. Cancer 4: 143-153.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
8
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi, A. et al. 2009. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat. Genet. 41: 1350-1353.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1350-1353
-
-
Doi, A.1
-
9
-
-
77956902023
-
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
-
Ji, H. et al. 2010. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 467: 338-342.
-
(2010)
Nature
, vol.467
, pp. 338-342
-
-
Ji, H.1
-
10
-
-
0026522204
-
Profound block in thymocyte development in mice lacking p56lck
-
Molina, T.J. et al. 1992. Profound block in thymocyte development in mice lacking p56lck. Nature 357: 161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
-
11
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
Luger, K. et al. 1997. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260.
-
(1997)
Nature
, vol.389
, pp. 251-260
-
-
Luger, K.1
-
12
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T. & C.D. Allis. 2001. Translating the histone code. Science 293: 1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
13
-
-
49449100095
-
Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming
-
Zardo, G., G. Cimino & C. Nervi. 2008. Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming. Leukemia 22: 1503-1518.
-
(2008)
Leukemia
, vol.22
, pp. 1503-1518
-
-
Zardo, G.1
Cimino, G.2
Nervi, C.3
-
14
-
-
40849139208
-
Epigenetics in cancer
-
Esteller, M. 2008. Epigenetics in cancer. N. Eng. J. Med. 358: 1148-1159.
-
(2008)
N. Eng. J. Med.
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
15
-
-
33750488431
-
The genomic landscape of histone modifications in human T cells
-
Roh, T.Y. et al. 2006. The genomic landscape of histone modifications in human T cells. Proc. Natl. Acad. Sci. USA 103: 15782-15787.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15782-15787
-
-
Roh, T.Y.1
-
16
-
-
58049191558
-
Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
-
Cui, K. et al. 2009. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4: 80-93.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 80-93
-
-
Cui, K.1
-
17
-
-
48949099045
-
Inferring causal relationships among different histone modifications and gene expression
-
Yu, H. et al. 2008. Inferring causal relationships among different histone modifications and gene expression. Genome Res. 18: 1314-1324.
-
(2008)
Genome Res.
, vol.18
, pp. 1314-1324
-
-
Yu, H.1
-
18
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl, B.D. & C.D. Allis. 2000. The language of covalent histone modifications. Nature 403: 41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
19
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara, V. et al. 2006. Chromatin signatures of pluripotent cell lines. Nat. Cell Biol. 8: 532-538.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 532-538
-
-
Azuara, V.1
-
20
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B.E. et al. 2006. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
21
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
Agger, K. et al. 2007. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449: 731-734.
-
(2007)
Nature
, vol.449
, pp. 731-734
-
-
Agger, K.1
-
22
-
-
36749082438
-
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
-
Hong, S. et al. 2007. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc. Natl. Acad. Sci. USA 104: 18439-18444.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18439-18444
-
-
Hong, S.1
-
23
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh, T. et al. 2010. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat. Immunol. 11: 936-944.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 936-944
-
-
Satoh, T.1
-
24
-
-
47549105128
-
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
-
Sen, G.L. et al. 2008. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev. 22: 1865-1870.
-
(2008)
Genes Dev.
, vol.22
, pp. 1865-1870
-
-
Sen, G.L.1
-
25
-
-
77952367798
-
Widespread transcription at neuronal activity-regulated enhancers
-
Kim, T.K. et al. 2010. Widespread transcription at neuronal activity-regulated enhancers. Nature 465: 182-187.
-
(2010)
Nature
, vol.465
, pp. 182-187
-
-
Kim, T.K.1
-
26
-
-
79959346470
-
Non-coding RNAs, epigenetic memory and the passage of information to progeny
-
Morris, K.V. 2009. Non-coding RNAs, epigenetic memory and the passage of information to progeny. RNA Biol. 6: 242-247.
-
(2009)
RNA Biol.
, vol.6
, pp. 242-247
-
-
Morris, K.V.1
-
27
-
-
67349157682
-
Tiny RNAs associated with transcription start sites in animals
-
Taft, R.J. et al. 2009. Tiny RNAs associated with transcription start sites in animals. Nat. Genet. 41: 572-578.
-
(2009)
Nat. Genet.
, vol.41
, pp. 572-578
-
-
Taft, R.J.1
-
28
-
-
60149099385
-
Evolution and functions of long noncoding RNAs
-
Ponting, C.P., P.L. Oliver & W. Reik. 2009. Evolution and functions of long noncoding RNAs. Cell 136: 629-641.
-
(2009)
Cell
, vol.136
, pp. 629-641
-
-
Ponting, C.P.1
Oliver, P.L.2
Reik, W.3
-
29
-
-
1942435249
-
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
-
Bartel, D.P. & C.Z. Chen. 2004. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5: 396-400.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 396-400
-
-
Bartel, D.P.1
Chen, C.Z.2
-
30
-
-
33846283385
-
The evolution of gene regulation by transcription factors and microRNAs
-
Chen, K. & N. Rajewsky. 2007. The evolution of gene regulation by transcription factors and microRNAs. Nat. Rev. Genet. 8: 93-103.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 93-103
-
-
Chen, K.1
Rajewsky, N.2
-
31
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen, C.Z. et al. 2004. MicroRNAs modulate hematopoietic lineage differentiation. Science 303: 83-86.
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
-
32
-
-
77958134349
-
Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia
-
Zimmerman, E.I. et al. 2010. Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia. Mol. Pharmacol. 78: 811-817.
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 811-817
-
-
Zimmerman, E.I.1
-
33
-
-
0037673945
-
Osteoclast differentiation and activation
-
Boyle, W.J., W.S. Simonet & D.L. Lacey. 2003. Osteoclast differentiation and activation. Nature 423: 337-342.
-
(2003)
Nature
, vol.423
, pp. 337-342
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
34
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
Karsenty, G. & E.F. Wagner. 2002. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2: 389-406.
-
(2002)
Dev. Cell
, vol.2
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
35
-
-
0034284970
-
Bone resorption by osteoclasts
-
Teitelbaum, S.L. 2000. Bone resorption by osteoclasts. Science 289: 1504-1508.
-
(2000)
Science
, vol.289
, pp. 1504-1508
-
-
Teitelbaum, S.L.1
-
36
-
-
28544452658
-
Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system
-
Tanaka, S. et al. 2005. Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system. Immunol. Rev. 208: 30-49.
-
(2005)
Immunol. Rev.
, vol.208
, pp. 30-49
-
-
Tanaka, S.1
-
37
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey, D.L. et al. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93: 165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
-
38
-
-
0032584208
-
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
-
Yasuda, H. et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA 95: 3597-3602.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3597-3602
-
-
Yasuda, H.1
-
39
-
-
27744432009
-
Autoamplification of NFATc1 expression determines its essential role in bone homeostasis
-
Asagiri, M. et al. 2005. Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J. Exp. Med. 202: 1261-1269.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1261-1269
-
-
Asagiri, M.1
-
40
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi, H. et al. 2002. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 3: 889-901.
-
(2002)
Dev. Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
-
41
-
-
0036289336
-
Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter
-
Kitazawa, R. & S. Kitazawa. 2002. Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter. Biochem. Biophys. Res. Commun. 290: 650-655.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.290
, pp. 650-655
-
-
Kitazawa, R.1
Kitazawa, S.2
-
42
-
-
77950429619
-
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption
-
Mizoguchi, F. et al. 2010. Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption. J. Cell Biochem. 109: 866-875.
-
(2010)
J. Cell Biochem.
, vol.109
, pp. 866-875
-
-
Mizoguchi, F.1
-
43
-
-
63249113375
-
Impaired micro-RNA pathways diminish osteoclast differentiation and function
-
Sugatani, T. & K.A. Hruska. 2009. Impaired micro-RNA pathways diminish osteoclast differentiation and function. J. Biol. Chem. 284: 4667-4678.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4667-4678
-
-
Sugatani, T.1
Hruska, K.A.2
-
44
-
-
79953686494
-
A microRNA expression signature of osteoclastogenesis
-
Sugatani, T., J. Vacher & K.A. Hruska. 2011. A microRNA expression signature of osteoclastogenesis. Blood 117: 3648-3657.
-
(2011)
Blood
, vol.117
, pp. 3648-3657
-
-
Sugatani, T.1
Vacher, J.2
Hruska, K.A.3
-
45
-
-
77957664009
-
miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate
-
Mann, M. et al. 2010. miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate. Proc. Natl. Acad. Sci. USA 107: 15804-15809.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 15804-15809
-
-
Mann, M.1
-
46
-
-
79959531020
-
Regulation of RANKL-induced osteoclastogenesis by TGF-beta through molecular interaction between Smad3 and Traf6
-
Yasui, T. et al. 2011. Regulation of RANKL-induced osteoclastogenesis by TGF-beta through molecular interaction between Smad3 and Traf6. J. Bone Miner. Res. 26: 1447-1456.
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 1447-1456
-
-
Yasui, T.1
|