Role of cytochrome P450 genotype in the steps toward personalized drug therapy

Pharmacogenomics and Personalized Medicine

Volumn 4, Issue 1, 2011, Pages 123-136

  Cavallari, Larisa H ^a   Jeong, Hyunyoung ^a   Bress, Adam ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Allele; Cytochrome P450; Drug metabolism; Genotype; Polymorphism

Indexed keywords

4' HYDROXYMEPHENYTOIN; ACETYLSALICYLIC ACID; AMOXICILLIN; ANTIDEPRESSANT AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CILOSTAZOL; CLARITHROMYCIN; CLOPIDOGREL; CODEINE; CYTOCHROME P450; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; ESOMEPRAZOLE; LANSOPRAZOLE; LOSARTAN; METOPROLOL; NARCOTIC ANALGESIC AGENT; NELFINAVIR; NEUROLEPTIC AGENT; OMEPRAZOLE; PRASUGREL; PROTON PUMP INHIBITOR; RABEPRAZOLE; TAMOXIFEN; TICAGRELOR; TOLBUTAMIDE; TRAMADOL; UNINDEXED DRUG; WARFARIN;

ABDOMINAL PAIN; ACUTE CORONARY SYNDROME; ALLELE; ANTICOAGULATION; BREAST CANCER; CARDIOVASCULAR DISEASE; CYTOCHROME P450 2C19 GENE; CYTOCHROME P450 2C9 GENE; CYTOCHROME P450 2D6 GENE; CYTOCHROME P450 GENE; DOSE CALCULATION; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG ELIMINATION; DRUG MECHANISM; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG TRANSFORMATION; ENZYME ACTIVITY; GASTROESOPHAGEAL REFLUX; GENE; GENE FUNCTION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HEART ATRIUM FIBRILLATION; HEART FAILURE; HELICOBACTER INFECTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERTENSION; LIVER METABOLISM; LOSS OF FUNCTION MUTATION; PERSONALIZED MEDICINE; PHARMACOGENOMICS; PROTEIN FUNCTION; RECOMMENDED DRUG DOSE; RESPIRATION DEPRESSION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; STENT THROMBOSIS; THROMBOEMBOLISM; UNSPECIFIED SIDE EFFECT;

EID: 83755194835     PISSN: None     EISSN: 11787066     Source Type: Journal    
DOI: 10.2147/pgpm.s15497     Document Type: Review

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