메뉴 건너뛰기




Volumn 308, Issue 3, 2004, Pages 965-974

Developmental Expression of Human Hepatic CYP2C9 and CYP2C19

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; DICLOFENAC; MEPHENYTOIN;

EID: 1342344547     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.060137     Document Type: Article
Times cited : (274)

References (34)
  • 2
    • 0026569586 scopus 로고
    • Cytochrome P450 and the arachidonate cascade
    • Capdevila JH, Falck JR and Estabrook RW (1992) Cytochrome P450 and the arachidonate cascade. FASEB J 6:731-736.
    • (1992) FASEB J , vol.6 , pp. 731-736
    • Capdevila, J.H.1    Falck, J.R.2    Estabrook, R.W.3
  • 3
    • 0029962261 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and hepatocyte differentiation
    • Cereghini S (1996) Liver-enriched transcription factors and hepatocyte differentiation. FASEB J 10:267-282.
    • (1996) FASEB J , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 4
    • 0042844649 scopus 로고    scopus 로고
    • Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter
    • Chen Y, Ferguson SS, Negishi M, and Goldstein JA (2003) Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. Mol Pharmacol 64:316-324.
    • (2003) Mol Pharmacol , vol.64 , pp. 316-324
    • Chen, Y.1    Ferguson, S.S.2    Negishi, M.3    Goldstein, J.A.4
  • 5
    • 0031661240 scopus 로고    scopus 로고
    • Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans
    • Edwards RJ, Adams DA, Watts PS, Davies DS, and Boobis AR (1998) Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans. Biochem Pharmacol 56:377-387.
    • (1998) Biochem Pharmacol , vol.56 , pp. 377-387
    • Edwards, R.J.1    Adams, D.A.2    Watts, P.S.3    Davies, D.S.4    Boobis, A.R.5
  • 6
    • 0037671388 scopus 로고    scopus 로고
    • Mechanism-based inactivation of cytochrome P450 2B6 by a novel terminal acetylene inhibitor
    • Fan PW, Gu C, Marsh SA, and Stevens JC (2003) Mechanism-based inactivation of cytochrome P450 2B6 by a novel terminal acetylene inhibitor. Drug Metab Dispos 31:28-36.
    • (2003) Drug Metab Dispos , vol.31 , pp. 28-36
    • Fan, P.W.1    Gu, C.2    Marsh, S.A.3    Stevens, J.C.4
  • 7
    • 0036765751 scopus 로고    scopus 로고
    • Regulation of human CYP2C9 by the constitutive androstane receptor: Discovery of a new distal binding site
    • Ferguson SS, LeCluyse EL, Negishi M, and Goldstein JA (2002) Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. Mol Pharmacol 62:737-746.
    • (2002) Mol Pharmacol , vol.62 , pp. 737-746
    • Ferguson, S.S.1    LeCluyse, E.L.2    Negishi, M.3    Goldstein, J.A.4
  • 8
    • 0037016761 scopus 로고    scopus 로고
    • Transcriptional regulation of CYP2C9 gene: Role of glucocorticoid receptor and constitutive androstane receptor
    • Gerbal-Chaloin S, Daujat M, Pascussi J-M, Pichard-Garcia L, Vilarem M-J, and Maurel P (2002) Transcriptional regulation of CYP2C9 gene: role of glucocorticoid receptor and constitutive androstane receptor. J Biol Chem 277:209-217.
    • (2002) J Biol Chem , vol.277 , pp. 209-217
    • Gerbal-Chaloin, S.1    Daujat, M.2    Pascussi, J.-M.3    Pichard-Garcia, L.4    Vilarem, M.-J.5    Maurel, P.6
  • 9
    • 0035028935 scopus 로고    scopus 로고
    • Relative contribution of CYP2C9 and -2C19 to phenytoin 4-hydroxylation in vitro: Inhibition by sulfaphenazole, omeprazole and ticlopidine
    • Giancarlo GM, Venkatakrishnan K, Granda BW, Von Moltke LL, and Greenblatt DJ (2001) Relative contribution of CYP2C9 and -2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole and ticlopidine. Eur J Clin Pharmacol 57:31-36.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 31-36
    • Giancarlo, G.M.1    Venkatakrishnan, K.2    Granda, B.W.3    Von Moltke, L.L.4    Greenblatt, D.J.5
  • 10
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • Goldstein JA (2001) Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol 52:349-355.
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 349-355
    • Goldstein, J.A.1
  • 12
    • 0025067462 scopus 로고
    • Molecular genetics of the P-450 superfamily
    • Gonzalez FJ (1990) Molecular genetics of the P-450 superfamily. Pharmacol Ther 45:1-38.
    • (1990) Pharmacol Ther , vol.45 , pp. 1-38
    • Gonzalez, F.J.1
  • 13
    • 0030587544 scopus 로고    scopus 로고
    • Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity and prochiral selectivity of the wild-type and I359L mutant forms
    • Haining RL, Hunter AP, Veronese ME, Trager WF, and Rettie AE (1996) Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity and prochiral selectivity of the wild-type and I359L mutant forms. Arch Biochem Biophys 333:447-458.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 447-458
    • Haining, R.L.1    Hunter, A.P.2    Veronese, M.E.3    Trager, W.F.4    Rettie, A.E.5
  • 14
    • 0036156595 scopus 로고    scopus 로고
    • The ontogeny of human drug metabolizing enzymes: Phase I oxidative enzymes
    • Hines RN and McCarver DG (2002) The ontogeny of human drug metabolizing enzymes: phase I oxidative enzymes. J Pharmacol Exp Ther 300:355-360.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 355-360
    • Hines, R.N.1    McCarver, D.G.2
  • 16
    • 0029035904 scopus 로고
    • Transcriptional regulation of human CYP2C genes: Functional comparison of CYP2C9 and CYP2C18 promoter regions
    • Ibeanu GC and Goldstein JA (1995) Transcriptional regulation of human CYP2C genes: functional comparison of CYP2C9 and CYP2C18 promoter regions. Biochemistry 34:8028-8036.
    • (1995) Biochemistry , vol.34 , pp. 8028-8036
    • Ibeanu, G.C.1    Goldstein, J.A.2
  • 17
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • Kaminsky LS and Zhang ZY (1997) Human P450 metabolism of warfarin. Pharmacol Ther 73:67-74.
    • (1997) Pharmacol Ther , vol.73 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.Y.2
  • 18
    • 0038482452 scopus 로고    scopus 로고
    • Role of the hepatocyte nuclear factor 4a in control of the pregnane X receptor during fetal liver development
    • Kamiya A, Inoue Y, and Gonzalez FJ (2003) Role of the hepatocyte nuclear factor 4a in control of the pregnane X receptor during fetal liver development. Hepatology 37:1375-1384.
    • (2003) Hepatology , vol.37 , pp. 1375-1384
    • Kamiya, A.1    Inoue, Y.2    Gonzalez, F.J.3
  • 19
    • 0032891790 scopus 로고    scopus 로고
    • Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele
    • Kidd RS, Straughn AB, Meyer MC, Blaisdell J, Goldstein JA, and Dalton JT (1999) Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele. Pharmacogenetics 9:71-90.
    • (1999) Pharmacogenetics , vol.9 , pp. 71-90
    • Kidd, R.S.1    Straughn, A.B.2    Meyer, M.C.3    Blaisdell, J.4    Goldstein, J.A.5    Dalton, J.T.6
  • 20
    • 0032604625 scopus 로고    scopus 로고
    • Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs
    • Klose TS, Blaisdell JA, and Goldstein JA (1999) Gene structure of CYP2C8 and extrahepatic distribution of the human CYP2Cs. J Biochem Mol Toxicol 13:289-295.
    • (1999) J Biochem Mol Toxicol , vol.13 , pp. 289-295
    • Klose, T.S.1    Blaisdell, J.A.2    Goldstein, J.A.3
  • 21
    • 0036157094 scopus 로고    scopus 로고
    • Human hepatic flavin-containing monooxygenase 1 (FMO1) and 3 (FMO3) developmental expression
    • Koukouritaki SB, Simpson P, Yeung CK, Rettie AE, and Hines RN (2002) Human hepatic flavin-containing monooxygenase 1 (FMO1) and 3 (FMO3) developmental expression. Pediatric Res 51:236-243.
    • (2002) Pediatric Res , vol.51 , pp. 236-243
    • Koukouritaki, S.B.1    Simpson, P.2    Yeung, C.K.3    Rettie, A.E.4    Hines, R.N.5
  • 22
    • 0027739383 scopus 로고
    • A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs
    • Leemann TD, Transon C, Bonnabry P, and Dayer P (1993) A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal antiinflammatory drugs. Drugs Exp Clin Res 19:189-195.
    • (1993) Drugs Exp Clin Res , vol.19 , pp. 189-195
    • Leemann, T.D.1    Transon, C.2    Bonnabry, P.3    Dayer, P.4
  • 24
    • 0037115525 scopus 로고    scopus 로고
    • Pharmacogenetics affects dosing, efficacy and toxicity of cytochrome P450-metabolized drugs
    • Rogers JF, Nafziger AN, and Bertino JS Jr (2002) Pharmacogenetics affects dosing, efficacy and toxicity of cytochrome P450-metabolized drugs. Am J Med 113:746-750.
    • (2002) Am J Med , vol.113 , pp. 746-750
    • Rogers, J.F.1    Nafziger, A.N.2    Bertino Jr., J.S.3
  • 25
    • 0027909072 scopus 로고
    • Purification of macaque liver flavin-containing monooxygenase: A form of the enzyme related immunochemically to an isozyme expressed selectively in adult human liver
    • Sadeque AJM, Thummel KE, and Rettie AE (1993) Purification of macaque liver flavin-containing monooxygenase: a form of the enzyme related immunochemically to an isozyme expressed selectively in adult human liver. Biochim Biophys Acta Protein Struct Mol Enzymol 1162:127-134.
    • (1993) Biochim Biophys Acta Protein Struct Mol Enzymol , vol.1162 , pp. 127-134
    • Sadeque, A.J.M.1    Thummel, K.E.2    Rettie, A.E.3
  • 26
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
    • Shimada T, Yamazaki H, Mimura M, Inui Y, and Guengerich FP (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J Pharmacol Exp Ther 270:414-423.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 414-423
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5
  • 28
    • 0033048695 scopus 로고    scopus 로고
    • Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac
    • Tang W, Stearns RA, Wang RW, Chiu SH, and Baillie TA (1999) Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac. Chem Res Toxicol 12:192-199.
    • (1999) Chem Res Toxicol , vol.12 , pp. 192-199
    • Tang, W.1    Stearns, R.A.2    Wang, R.W.3    Chiu, S.H.4    Baillie, T.A.5
  • 30
    • 0030699162 scopus 로고    scopus 로고
    • Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: In vivo/in vitro correlation and inducibility
    • Treluyer J-M, Gueret G, Cheron G, Sonnier M, and Cresteil T (1997) Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: in vivo/in vitro correlation and inducibility. Pharmacogenetics 7:441-452.
    • (1997) Pharmacogenetics , vol.7 , pp. 441-452
    • Treluyer, J.-M.1    Gueret, G.2    Cheron, G.3    Sonnier, M.4    Cresteil, T.5
  • 31
    • 0036367792 scopus 로고    scopus 로고
    • Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response
    • Wei P, Zhang J, Dowhan DH, Han Y, and Moore DD (2002) Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response. Pharmacogenomics J 2:117-126.
    • (2002) Pharmacogenomics J , vol.2 , pp. 117-126
    • Wei, P.1    Zhang, J.2    Dowhan, D.H.3    Han, Y.4    Moore, D.D.5
  • 32
    • 0034010930 scopus 로고    scopus 로고
    • CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes
    • Wester MR, Lasker JM, Johnson EF, and Raucy JL (2000) CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes. Drug Metab Dispos 28:354-359.
    • (2000) Drug Metab Dispos , vol.28 , pp. 354-359
    • Wester, M.R.1    Lasker, J.M.2    Johnson, E.F.3    Raucy, J.L.4
  • 33
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P450 2C19: Correlation between 2C19 and S-mephenytoin 4′-hydroxylation
    • Wrighton SA, Stevens JC, Becker GW, and Vandenbranden M (1993) Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4′-hydroxylation. Arch Biochem Biophys 306:240-245.
    • (1993) Arch Biochem Biophys , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    Vandenbranden, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.