Anticancer effects of imperatorin isolated from Angelica dahurica: Induction of apoptosis in HepG2 cells through both death-receptor- and mitochondria-mediated pathways

Chemotherapy

Volumn 57, Issue 6, 2012, Pages 449-459

  Luo, Ke Wang ^a,b   Sun, Jian Guo ^a,b   Chan, Judy Yuet Wa ^b,c   Yang, Lu ^a,b   Wu, Shi Hua ^a,b   Fung, Kwok Pui ^b,c   Liu, Fei Yan ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c Faculty of Medicine   (Hong Kong)

Author keywords

Anticancer effect cancer; Apoptosis; HepG2; Imperatorin; Metastasis

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR; PENTOSALEN; PHOSPHATIDYLSERINE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

ANGELICA DAHURICA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DRUG EFFECT; DRUG ISOLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; WEIGHT REDUCTION; WESTERN BLOTTING;

ANGELICA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HEP G2 CELLS; HL-60 CELLS; HT29 CELLS; HUMANS; MALE; MICE; MICE, NUDE; MITOCHONDRIA; PLANT ROOTS; PSORALENS; RECEPTORS, DEATH DOMAIN; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 83755182761     PISSN: 00093157     EISSN: 14219794     Source Type: Journal    
DOI: 10.1159/000331641     Document Type: Article

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