In Vitro and in Vivo anticancer activity of a synthetic glycolipid as toll-like receptor 4 (TLR4) activator

Journal of Biological Chemistry

Volumn 286, Issue 51, 2011, Pages 43782-43792

  Lin, Yong Shiang ^a   Huang, Li De ^b   Lin, Chao Hsiung ^a   Huang, Po Hsiung ^a   Chen, Yu Jen ^c   Wong, Fen Hwa ^a   Lin, Chun Cheng ^b   Fu, Shu Ling ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE IMMUNITY; ANTICANCER ACTIVITIES; APOPTOTIC PATHWAYS; CANCER CELLS; CANCER IMMUNOTHERAPY; CHEMOKINES; CONDITIONED MEDIUM; CYTOKINES; GLYCO LIPIDS; IMMUNOSTIMULANTS; IN-VITRO; INNATE IMMUNE RESPONSE; MOLECULAR BASIS; RELATIONSHIP ANALYSIS; SIGNALING PATHWAYS; SPLENOCYTES; SUGAR MOIETY; SURVIVAL RATE; THERAPEUTIC POTENTIALS; TOLL-LIKE RECEPTOR 4; TUMOR GROWTH; TUMOR SITE;

AMINO ACIDS; CELL DEATH; DISEASES; GLUCOSE; MAMMALS; TUMORS;

CHEMICAL ACTIVATION;

CASPASE 3; CCL 34; CD11B ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOLIPID; GLYCOPROTEIN P 15095; INTERLEUKIN 12; N(G) METHYLARGININE; PICIBANIL; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL ACTIVATION; CELL ISOLATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SPLEEN CELL; STRUCTURE ACTIVITY RELATION; SURVIVAL RATE; TUMOR IMMUNITY;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOHYDRATES; CASPASE 3; CELL DEATH; CELL LINE; DRUG DELIVERY SYSTEMS; GLYCOLIPIDS; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED C3H; NEOPLASMS; NITRIC OXIDE SYNTHASE TYPE II; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4;

EID: 83755181458     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.285171     Document Type: Article

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