Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothionein

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 5 50-5, 2004, Pages

  Tomita, Kengo ^a   Azuma, Toshifumi ^b   Kitamura, Naoto ^a   Tamiya, Gen ^c   Ando, Satoshi ^c   Nagata, Hiroshi ^a   Kato, Shinzo ^a   Inokuchi, Sayaka ^a   Nishimura, Takeshi ^a   Ishii, Hiromasa ^a   Hibi, Toshifumi ^a,d  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKAI UNIVERSITY   (Japan)

^d KEIO UNIVERSITY   (Japan)

Author keywords

Oxidative stress; Tumor necrosis factor ; Zinc

Indexed keywords

ALCOHOL; ANTIOXIDANT; LEPTIN; LEPTIN RECEPTOR; LIPID; MESSENGER RNA; METALLOTHIONEIN; METALLOTHIONEIN I; METALLOTHIONEIN II; PROTEIN; UNCLASSIFIED DRUG; ZINC;

ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ALCOHOLIC STEATOHEPATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; LIPID PEROXIDATION; LIVER CELL; LIVER INJURY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; DRUG ADMINISTRATION SCHEDULE; ETHANOL; FATTY LIVER; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; KUPFFER CELLS; LEPTIN; MALE; METALLOTHIONEIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, ZUCKER; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; ZINC;

EID: 7044272742     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00107.2004     Document Type: Article

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