The influence of tumour necrosis factor-α (TNF-α) on amyloid-β (Aβ)-degrading enzymes in vitro

International Journal of Molecular Epidemiology and Genetics

Volumn 2, Issue 4, 2011, Pages 409-415

  Culpan, Doris ^a   Palmer, Jennifer ^a   Scott Miners, J ^a   Love, Seth ^a   Kehoe, Patrick G ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Alzheimer's disease; Inflammation; RT PCR; SH SY5Y cells; TNF ; Western blot

Indexed keywords

AMYLOID BETA PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN CONVERTING ENZYME; INSULINASE; MEMBRANE METALLOENDOPEPTIDASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION AND TRANSLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; NEUROBLASTOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL; WESTERN BLOTTING;

EID: 83655211653     PISSN: None     EISSN: 19481756     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Paresce DM, Chung H and Maxfield FR. Slow Degradation of Aggregates of the Alzheimer's Disease Amyloid β-Protein by Microglial Cells. Journal of Biological Chemistry 1997; 272: 29390-29397
2. Qiu WQ, Ye Z, Kholodenko D, Seubert P and Selkoe DJ. Degradation of Amyloid β-Protein by a Metalloprotease Secreted by Microglia and Other Neural and Non-neural Cells. Journal of Biological Chemistry 1997; 272: 6641-6646
3. Hickman SE, Allison EK and El Khoury J. Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice. J Neurosci 2008; 28: 8354-8360
4. Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, Holtzman DM, Miller CA, Strickland DK, Ghiso J and Zlokovic BV. Clearance of Alzheimer's amyloid-β1-40 peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. The Journal of Clinical Investigation 2000; 106: 1489-1499
5. Kuhnke D, Jedlitschky G, Grube M, Krohn M, Jucker M, Mosyagin I, Cascorbi I, Walker LC, Kroemer HK, Warzok RW and Vogelgesang S. MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's Amyloid-β Peptides-Implications for the Mechanisms of Aβ Clearance at the Blood-Brain Barrier. Brain Pathology 2007; 17: 347-353
6. Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP and Selkoe DJ. Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature Death. Neuron 2003; 40: 1087-1093
7. [] Deng-Shun Wang DWD and James S. Malter. β-Amyloid Degradation and Alzheimer's Disease. Journal of Biomedicine and Biotechnology 2006; Article ID 58406 doi: 10.1155/ JBB/2006/58406
8. Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG and Love S. Abeta-degrading enzymes in Alzheimer's disease. Brain Pathology 2008; 18: 240-252
9. Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral Amyloid Angiopathy Amyloid β Accumulates in Putative Interstitial Fluid Drainage Pathways in Alzheimer's Disease. Am J Pathol 1998; 153: 725-733
10. Weller RO, Massey A, Newman TA, Hutchings M, Kuo YM, Roher AE. Cerebral amyloid angiopathy: amyloid β accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease. Am J Pathol 1998; 153: 725-33
11. Preston SD, Steart PV, Wilkinson A, Nicoll JAR and Weller RO. Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid β from the human brain. Neuropathology and Applied Neurobiology 2003; 29: 106-117
12. McGeer P, McGeer E. Local neuroinflammation and the progression of Alzheimer's disease. J Neurovirol 2002; 8: 529-538
13. Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. Journal of Neuroimmunology 2007; 184: 69-91
14. Boche D, Nicoll JA. SYMPOSIUM: Clearance of Aβ from the Brain in Alzheimer' Disease: The Role of the Immune System in Clearance of Aβ from the Brain. Brain Pathology 2008; 18: 267-278
15. Gong C, Qin Z, Betz AL, Liu XH and Yang GY. Cellular localization of tumor necrosis factor alpha following focal cerebral ischemia in mice. Brain Research 1998; 801: 1-8
16. Orzylowska O, Oderfeld-Nowak B, Zaremba M, Januszewski S and Mossakowski M. Prolonged and concomitant induction of astroglial immunoreactivity of interleukin-1β and interleukin-6 in the rat hippocampus after transient global ischemia. Neuroscience Letters 1999; 263: 72-76
17. Chao C, Hu S, Frey W, 2nd, Ala T, Tourtellotte W and Peterson P. Transforming growth factor beta in Alzheimer's disease. Clin Diagn Lab Immunol 1994; 1: 109-110
18. Tarkowski E, Blennow K, Wallin A and Tarkowski A. Intracerebral production of tumor necrosis factor-α, a local neuroprotective agent, in Alzheimer disease and vascular dementia. J Clin Immunol 1999; 19: 223-230
19. Perry RT, Collins JS, Wiener H, Acton R and Go RCP. The role of TNF and its receptors in Alzheimer's disease. Neurobiology of Aging 2001; 22: 873-883
20. Stefano GB, Paemen LR and Hughes Jr TK. Autoimmunoregulation: differential modulation of CD10/neutral endopeptidase 24.11 by tumor necrosis factor and neuropeptides. Journal of Neuroimmunology 1992; 41: 9-14
21. Zhao RZ, Chen X, Yao Q and Chen C. TNF-α induces interleukin-8 and endothelin-1 expression in human endothelial cells with different redox pathways. Biochemical and Biophysical Research Communications 2005; 327: 985-992
22. Yamamoto M, Kiyota T, Walsh SM, Liu J, Kipnis J and Ikezu T. Cytokine-Mediated Inhibition of Fibrillar Amyloid-β Peptide Degradation by Human Mononuclear Phagocytes. The Journal of Immunology 2008; 181: 3877-3886
23. Saijonmaa O, Nyman T and Fyhrquist F. Downregulation of Angiotensin-Converting Enzyme by Tumor Necrosis Factor-α and Interleukin-1β in Cultured Human Endothelial Cells. Journal of Vascular Research 2001; 38: 370-378
24. Viinikainen A, Nyman T, Fyhrquist F and Saijonmaa O. Downregulation of angiotensin converting enzyme by TNF-α in differentiating human macrophages. Cytokine 2002; 18: 304-310
25. Kenchappa P, Yadav A, Singh G, Nandana S and Banerjee K. Rescue of TNFα-inhibited neuronal cells by IGF-1 involves Akt and c-Jun Nterminal kinases. Journal of Neuroscience Research 2004; 76: 466-474
26. Culpan D, Cram D, Chalmers K, Cornish A, Palmer L, Palmer J, Hughes A, Passmore P, Craigs D, Wilcock GK, Kehoe PG and Love S. TNFR-associated factor-2 (TRAF-2) in Alzheimer's disease. Neurobiology of Aging 2009; 30: 1052-1060
27. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408
28. Palmer JC, Baig S, Kehoe PG and Love S. Endothelin-Converting Enzyme-2 Is Increased in Alzheimer's Disease and Up-Regulated by Aβ. Am J Pathol 2009; 175: 262-270
29. Yang SK, Wang YC, Chao CC, Chuang YJ, Lan CY and Chen BS. Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFα-induced inflammatory responses. BMC Medical Genomics 2010; 3: 19
30. Streit W. Microglia and Alzheimer's disease pathogenesis. J Neurosci Res 2004; 77: 1-8
31. Krause DL, Müller N. Neuroinflammation, Microglia and Implications for Anti-Inflammatory Treatment in Alzheimer's Disease. International Journal of Alzheimer's Disease 2010; Article ID 732806. doi: 10.4061/2010/732806 vol
32. Yamamoto M, Kiyota T, Horiba M, Buescher JL, Walsh SM, Gendelman HE and Ikezu T. Interferon-γ and Tumor Necrosis Factor-α Regulate Amyloid-β Plaque Deposition and β-Secretase Expression in Swedish Mutant APP Transgenic Mice. Am J Pathol 2007; 170: 680-692
33. Liao YF, Wang BJ, Cheng HT, Kuo LH and Wolfe MS. Tumor Necrosis Factor-α, Interleukin-1β, and Interferon-γ Stimulate γ-Secretasemediated Cleavage of Amyloid Precursor Protein through a JNK-dependent MAPK Pathway. Journal of Biological Chemistry 2004; 279: 49523-49532
34. Eckman EA, Watson M, Marlow L, Sambamurti K and Eckman CB. Alzheimer's Disease β-Amyloid Peptide Is Increased in Mice Deficient in Endothelin-converting Enzyme. Journal of Biological Chemistry 2003; 278: 2081-2084
35. Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC and Devi LA. Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes, Brain and Behavior 2008; 7: 418-426
36. Palmer J, Love S. Endothelin receptor antagonists: Potential in Alzheimer's disease. Pharmacological Research 2011; 63: 525-531
37. Emoto N, Yanagisawa M. Endothelin-converting Enzyme-2 Is a Membrane-bound, Phosphoramidon-sensitive Metalloprotease with Acidic pH Optimum. Journal of Biological Chemistry 1995; 270: 15262-15268
38. Cheng B, Christakos S and Mattson MP. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 1994; 12: 139-153
39. Berk B, Abe J, Min W, Surapisitchat J and Yan C. Endothelial atheroprotective and antiinflammatory mechanisms. Ann N Y Acad Sci 2001; 947: 93-109
40. Cheong R, Bergmann A, Werner S, Regal J, Hoffmann A and Levchenko A. Transient IκB kinase activity mediates temporal NF-κB dynamics in response to a wide range of tumor necrosis factor-alpha doses. J Biol Chem 2006; 281: 2945-2950
41. Erhuma M, Köbel M, Mustafa T, Wulfänger J, Dralle H, Hoang-Vu C, Langner J, Seliger B and Kehlen A. Expression of neutral endopeptidase (NEP/CD10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues. International Journal of Cancer 2007; 120: 2393-2400
42. Nelson PT, Keller JN. RNA in Brain Disease: No Longer Just The Messenger in the Middle. J Neuropathol Exp Neurol 2007; 66: 461-468.