Downregulation of angiotensin-converting enzyme by tumor necrosis factor-α and interleukin-1β in cultured human endothelial cells

Journal of Vascular Research

Volumn 38, Issue 4, 2001, Pages 370-378

  Saijonmaa, Outi ^a,b   Nyman, Tuulikki ^a   Fyhrquist, Frej ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

Author keywords

Cell culture; Cytokines; Endothelial function; Renin angiotensin system

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN; BRADYKININ; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE; HYDROCORTISONE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P44; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL WALL; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REGULATORY MECHANISM;

CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYDROCORTISONE; INTERLEUKIN-1; KINETICS; LYMPHOKINES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDYL-DIPEPTIDASE A; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0034924537     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000051068     Document Type: Article

References (27)

1. Biochemistry of angiotensin I-converting enzyme
2. Cardiac, vascular, and intrarenal renin-angiotensin systems in normal physiology and disease
3. Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease
4. Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans
5. Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit
6. Reversal of left ventricular hypertrophy in hypertensive patients. A metaanalysis of 109 treatment studies
7. Stimulation of bovine pulmonary artery endothelial cell ACE by dexamethasone: Involvement of steroid receptors
8. Mechanism of increased angiotensin-converting enzyme activity stimulated by platelet-activating factor
9. Effect of endothelin on angiotensin converting enzyme activity in cultured pulmonary artery endothelial cells
10. Upregulation of angiotensin converting enzyme by atrial natriuretic peptide and cyclic GMP in human endothelial cells
11. Induction of angiotensin converting enzyme by oncostatin M in human endothelial cells
12. Induction of angiotensin I-converting enzyme transcription by a protein kinase C-dependent mechanism in human endothelial cells
13. Rat angiotensin-converting enzyme promoter regulation by beta-adrenergics and cAMP in endothelium
14. The pathogenesis of atherosclerosis: A perspective for the 1990s
15. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
16. Inhibitor binding assay for angiotensin converting enzyme
17. Lipopolysaccharides decrease angiotensin converting enzyme activity expressed by cultured human endothelial cells
18. Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA
19. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning
20. Monocyte- and cytokine-induced downregulation of angiotensin-converting enzyme in cultured human and porcine endothelial cells
21. Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase
22. The MKK6/p38 stress kinase cascade is critical for tumor necrosis factor-α-induced expression of monocyte-chemoattractant protein-1 in endothelial cells
23. Induction of the E-selectin promoter by interleukin 1 and tumor necrosis factor α, and inhibition by glucocorticoids
24. Angiotensin, LDL peroxidation and atherosclerosis
25. The biology of vascular endothelial growth factor
26. Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells
27. Angiotensin II potentiates vascular endothelial growth factor-induced angiogenic activity in retinal microcapillary endothelial cells