-
1
-
-
0037015052
-
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
-
DOI 10.1073/pnas.182425099
-
Lohoff M, Mittrucker HW, Prechtl S, Bischof S, Sommer F, Kock S, et al., Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc Natl Acad Sci USA 2002; 99: 11808-11812. (Pubitemid 34994480)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11808-11812
-
-
Lohoff, M.1
Mittrucker, H.-W.2
Prechtl, S.3
Bischof, S.4
Sommer, F.5
Kock, S.6
Ferrick, D.A.7
Duncan, G.S.8
Gessner, A.9
Mak, T.W.10
-
2
-
-
0037147204
-
Modulation of T cell cytokine production by interferon regulatory factor-4
-
DOI 10.1074/jbc.M205895200
-
Hu CM, Jang SY, Fanzo JC, Pernis AB,. Modulation of T cell cytokine production by interferon regulatory factor-4. J Biol Chem 2002; 277: 49238-49246. (Pubitemid 36014353)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49238-49246
-
-
Hu, C.-M.1
Jang, S.Y.2
Fanzo, J.C.3
Pernis, A.B.4
-
3
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
DOI 10.1084/jem.20011128
-
Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH,. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med 2002; 195: 1003-1012. (Pubitemid 34412002)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.8
, pp. 1003-1012
-
-
Rengarajan, J.1
Mowen, K.A.2
McBride, K.D.3
Smith, E.D.4
Singh, H.5
Glimcher, L.H.6
-
4
-
-
57349118423
-
Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells
-
Honma K, Kimura D, Tominaga N, Miyakoda M, Matsuyama T, Yui K,. Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells. Proc Natl Acad Sci USA 2008; 105: 15890-15895.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15890-15895
-
-
Honma, K.1
Kimura, D.2
Tominaga, N.3
Miyakoda, M.4
Matsuyama, T.5
Yui, K.6
-
5
-
-
33947207887
-
Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation
-
Lund RJ, Loytomaki M, Naumanen T, Dixon C, Chen Z, Ahlfors H, et al., Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation. J Immunol 2007; 178: 3648-3660. (Pubitemid 46417632)
-
(2007)
Journal of Immunology
, vol.178
, Issue.6
, pp. 3648-3660
-
-
Lund, R.J.1
Loytomaki, M.2
Naumanen, T.3
Dixon, C.4
Chen, Z.5
Ahlfors, H.6
Tuomela, S.7
Tahvanainen, J.8
Scheinin, J.9
Henttinen, T.10
Rasool, O.11
Lahesmaa, R.12
-
6
-
-
68149125188
-
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines
-
Ahyi AN, Chang HC, Dent AL, Nutt SL, Kaplan MH,. IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J Immunol 2009; 183: 1598-1606.
-
(2009)
J Immunol
, vol.183
, pp. 1598-1606
-
-
Ahyi, A.N.1
Chang, H.C.2
Dent, A.L.3
Nutt, S.L.4
Kaplan, M.H.5
-
7
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, et al., Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 2010; 33: 192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
Bothur, E.2
Klein, M.3
Lingnau, K.4
Reuter, S.5
Grebe, N.6
-
8
-
-
77956361520
-
Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice
-
Biswas PS, Gupta S, Chang E, Song L, Stirzaker RA, Liao JK, et al., Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice. J Clin Invest 2010; 120: 3280-3295.
-
(2010)
J Clin Invest
, vol.120
, pp. 3280-3295
-
-
Biswas, P.S.1
Gupta, S.2
Chang, E.3
Song, L.4
Stirzaker, R.A.5
Liao, J.K.6
-
9
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y, Chaudhry A, Kas A, deRoos P, Kim JM, Chu TT, et al., Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 2009; 458: 351-356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
Deroos, P.4
Kim, J.M.5
Chu, T.T.6
-
10
-
-
73249136480
-
IRF4 and its regulators: Evolving insights into the pathogenesis of inflammatory arthritis?
-
Biswas PS, Bhagat G, Pernis AB,. IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis? Immunol Rev 2010; 233: 79-96.
-
(2010)
Immunol Rev
, vol.233
, pp. 79-96
-
-
Biswas, P.S.1
Bhagat, G.2
Pernis, A.B.3
-
11
-
-
79955835559
-
IRF4 regulates IL-17A promoter activity and controls RORgammat-dependent Th17 colitis in vivo
-
Mudter J, Yu J, Zufferey C, Brustle A, Wirtz S, Weigmann B, et al., IRF4 regulates IL-17A promoter activity and controls RORgammat-dependent Th17 colitis in vivo. Inflamm Bowel Dis 2011; 17: 1343-1358.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1343-1358
-
-
Mudter, J.1
Yu, J.2
Zufferey, C.3
Brustle, A.4
Wirtz, S.5
Weigmann, B.6
-
12
-
-
77952711172
-
Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma
-
Kim BS, Kim IK, Park YJ, Kim YS, Kim YJ, Chang WS, et al., Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma. Proc Natl Acad Sci USA 2010; 107: 8742-8747.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8742-8747
-
-
Kim, B.S.1
Kim, I.K.2
Park, Y.J.3
Kim, Y.S.4
Kim, Y.J.5
Chang, W.S.6
-
13
-
-
70349312354
-
ChIP-seq: Advantages and challenges of a maturing technology
-
Park PJ,. ChIP-seq: advantages and challenges of a maturing technology. Nat Rev Gen 2009; 10: 669-680.
-
(2009)
Nat Rev Gen
, vol.10
, pp. 669-680
-
-
Park, P.J.1
-
14
-
-
71249086283
-
Increased IFN-gamma activity in seasonal allergic rhinitis is decreased by corticosteroid treatment
-
Wang H, Barrenas F, Bruhn S, Mobini R, Benson M,. Increased IFN-gamma activity in seasonal allergic rhinitis is decreased by corticosteroid treatment. J Allergy Clin Immunol 2009; 124: 1360-1362.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 1360-1362
-
-
Wang, H.1
Barrenas, F.2
Bruhn, S.3
Mobini, R.4
Benson, M.5
-
15
-
-
77956526237
-
C-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
-
Nakata Y, Brignier AC, Jin S, Shen Y, Rudnick SI, Sugita M, et al., c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development. Blood 2010; 116: 1280-1290.
-
(2010)
Blood
, vol.116
, pp. 1280-1290
-
-
Nakata, Y.1
Brignier, A.C.2
Jin, S.3
Shen, Y.4
Rudnick, S.I.5
Sugita, M.6
-
16
-
-
33845483452
-
Modulatory role for retinoid-related orphan receptor α in allergen-induced lung inflammation
-
DOI 10.1164/rccm.200510-1672OC
-
Jaradat M, Stapleton C, Tilley SL, Dixon D, Erikson CJ, McCaskill JG, et al., Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation. Am J Respir Crit Care Med 2006; 174: 1299-1309. (Pubitemid 44913031)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.174
, Issue.12
, pp. 1299-1309
-
-
Jaradat, M.1
Stapleton, C.2
Tilley, S.L.3
Dixon, D.4
Erikson, C.J.5
McCaskill, J.G.6
Hong, S.K.7
Angers, M.8
Liao, G.9
Collins, J.10
Grissom, S.11
Jetten, A.M.12
-
17
-
-
0034608416
-
T cell receptor-induced calcineurin activation-regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex
-
DOI 10.1084/jem.191.11.1869
-
Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C, Kamata T, et al., T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex. J Exp Med 2000; 191: 1869-1879. (Pubitemid 30390350)
-
(2000)
Journal of Experimental Medicine
, vol.191
, Issue.11
, pp. 1869-1879
-
-
Yamashita, M.1
Katsumata, M.2
Iwashima, M.3
Kimura, M.4
Shimizu, C.5
Kamata, T.6
Shin, T.7
Seki, N.8
Suzuki, S.9
Taniguchi, M.10
Nakayama, T.11
-
18
-
-
0032538985
-
C-maf Promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms
-
DOI 10.1084/jem.188.10.1859
-
Ho IC, Lo D, Glimcher LH,. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms. J Exp Med 1998; 188: 1859-1866. (Pubitemid 28536773)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.10
, pp. 1859-1866
-
-
Ho, I.-C.1
Lo, D.2
Glimcher, L.H.3
-
19
-
-
0033617297
-
Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1
-
Blumenthal SG, Aichele G, Wirth T, Czernilofsky AP, Nordheim A, Dittmer J,. Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1. J Biol Chem 1999; 274: 12910-12916.
-
(1999)
J Biol Chem
, vol.274
, pp. 12910-12916
-
-
Blumenthal, S.G.1
Aichele, G.2
Wirth, T.3
Czernilofsky, A.P.4
Nordheim, A.5
Dittmer, J.6
-
20
-
-
36548999223
-
Ets-1 is a negative regulator of Th17 differentiation
-
DOI 10.1084/jem.20070994
-
Moisan J, Grenningloh R, Bettelli E, Oukka M, Ho IC,. Ets-1 is a negative regulator of Th17 differentiation. J Exp Med 2007; 204: 2825-2835. (Pubitemid 350179553)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.12
, pp. 2825-2835
-
-
Moisan, J.1
Grenningloh, R.2
Bettelli, E.3
Oukka, M.4
Ho, I.-C.5
-
21
-
-
49649104975
-
Role of Ets-1 phosphorylation in the effector function of Th cells
-
Grenningloh R, Miaw SC, Moisan J, Graves BJ, Ho IC,. Role of Ets-1 phosphorylation in the effector function of Th cells. Eur J Immunol 2008; 38: 1700-1705.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1700-1705
-
-
Grenningloh, R.1
Miaw, S.C.2
Moisan, J.3
Graves, B.J.4
Ho, I.C.5
-
22
-
-
77949329601
-
Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus
-
Strempel JM, Grenningloh R, Ho IC, Vercelli D,. Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus. J Immunol 2010; 184: 1309-1316.
-
(2010)
J Immunol
, vol.184
, pp. 1309-1316
-
-
Strempel, J.M.1
Grenningloh, R.2
Ho, I.C.3
Vercelli, D.4
-
23
-
-
53149154521
-
Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression
-
Cimmino L, Martins GA, Liao J, Magnusdottir E, Grunig G, Perez RK, et al., Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression. J Immunol 2008; 181: 2338-2347.
-
(2008)
J Immunol
, vol.181
, pp. 2338-2347
-
-
Cimmino, L.1
Martins, G.A.2
Liao, J.3
Magnusdottir, E.4
Grunig, G.5
Perez, R.K.6
-
24
-
-
27944459341
-
Activation of the mammalian immune system by siRNAs
-
DOI 10.1038/nbt1161, PII N1161
-
Marques JT, Williams BR,. Activation of the mammalian immune system by siRNAs. Nat Biotechnol 2005; 23: 1399-1405. (Pubitemid 41679392)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.11
, pp. 1399-1405
-
-
Marques, J.T.1
Williams, B.R.G.2
-
25
-
-
33846847949
-
T-cell responses to allergens
-
DOI 10.1016/j.jaci.2006.11.008, PII S0091674906023499
-
Woodfolk JA,. T-cell responses to allergens. J Allergy Clin Immunol 2007; 119: 280-294; quiz 295-286. (Pubitemid 46204819)
-
(2007)
Journal of Allergy and Clinical Immunology
, vol.119
, Issue.2
, pp. 280-294
-
-
Woodfolk, J.A.1
-
26
-
-
77649252969
-
A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease
-
Bosco A, McKenna KL, Firth MJ, Sly PD, Holt PG,. A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease. J Immunol 2009; 182: 6011-6021.
-
(2009)
J Immunol
, vol.182
, pp. 6011-6021
-
-
Bosco, A.1
McKenna, K.L.2
Firth, M.J.3
Sly, P.D.4
Holt, P.G.5
-
27
-
-
33748575899
-
Treatment of allergic asthma by targeting transcription factors using nucleic-acid based technologies
-
DOI 10.2174/138161206778194150
-
Sel S, Henke W, Dietrich A, Herz U, Renz H,. Treatment of allergic asthma by targeting transcription factors using nucleic-acid based technologies. Curr Pharm Des 2006; 12: 3293-3304. (Pubitemid 44364138)
-
(2006)
Current Pharmaceutical Design
, vol.12
, Issue.25
, pp. 3293-3304
-
-
Sel, S.1
Henke, W.2
Dietrich, A.3
Herz, U.4
Renz, H.5
-
28
-
-
62649129291
-
A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation
-
Mobini R, Andersson BA, Erjefalt J, Hahn-Zoric M, Langston MA, Perkins AD, et al., A module-based analytical strategy to identify novel disease-associated genes shows an inhibitory role for interleukin 7 Receptor in allergic inflammation. BMC Syst Biol 2009; 3: 19.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 19
-
-
Mobini, R.1
Andersson, B.A.2
Erjefalt, J.3
Hahn-Zoric, M.4
Langston, M.A.5
Perkins, A.D.6
-
29
-
-
47049120726
-
IRF4 addiction in multiple myeloma
-
DOI 10.1038/nature07064, PII NATURE07064
-
Shaffer AL, Emre NC, Lamy L, Ngo VN, Wright G, Xiao W, et al., IRF4 addiction in multiple myeloma. Nature 2008; 454: 226-231. (Pubitemid 351969894)
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 226-231
-
-
Shaffer, A.L.1
Emre, N.C.T.2
Lamy, L.3
Ngo, V.N.4
Wright, G.5
Xiao, W.6
Powell, J.7
Dave, S.8
Yu, X.9
Zhao, H.10
Zeng, Y.11
Chen, B.12
Epstein, J.13
Staudt, L.M.14
-
30
-
-
12744262855
-
Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma
-
Cho SH, Stanciu LA, Holgate ST, Johnston SL,. Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma. Am J Respir Crit Care Med 2005; 171: 224-230.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 224-230
-
-
Cho, S.H.1
Stanciu, L.A.2
Holgate, S.T.3
Johnston, S.L.4
-
31
-
-
78651299880
-
Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation
-
Pedicini M, Barrenas F, Clancy T, Castiglione F, Hovig E, Kanduri K, et al., Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation. PLoS Comput Biol 2010; 6: e1001032.
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Pedicini, M.1
Barrenas, F.2
Clancy, T.3
Castiglione, F.4
Hovig, E.5
Kanduri, K.6
|