The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more?

Biochimie

Volumn 94, Issue 1, 2012, Pages 110-116

  Akhter, Yusuf ^a   Ehebauer, Matthias T ^a   Mukhopadhyay, Sangita ^b   Hasnain, Seyed E ^c,d,e  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS   (India)

^c INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^d INSTITUTE OF LIFE SCIENCES   (India)

^e INSTITUTE OF LIVER AND BILIARY SCIENCES   (India)

Author keywords

Antigenic variation; Mycobacterium tuberculosis; PE PPE; Virulence factor

Indexed keywords

BACTERIAL PROTEIN; CYTOKINE; GAMMA INTERFERON; GLUTAMIC ACID DERIVATIVE; PROLINE GLUTAMATE; PROLINE PROLINE GLUTAMATE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANTIGENIC VARIATION; BACTERIAL GENOME; BACTERIAL MEMBRANE; BACTERIAL SURVIVAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CELLULAR IMMUNITY; CRYSTAL STRUCTURE; EFFECTOR CELL; GENE DELETION; GENE DUPLICATION; GENE EXPRESSION; HOST PATHOGEN INTERACTION; IMMUNE RESPONSE; IMMUNOMODULATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MEMORY T LYMPHOCYTE; MULTIGENE FAMILY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYLOGENY; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SURFACE PROPERTY; T LYMPHOCYTE; UPREGULATION;

ANTIGENS, BACTERIAL; BACTERIAL VACCINES; GENES, BACTERIAL; HUMANS; MULTIGENE FAMILY; MYCOBACTERIUM; VIRULENCE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 83555165187     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.09.026     Document Type: Review

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