Notch-induced hIL-6 production facilitates the maintenance of self-renewal of hCD34 + cord blood cells through the activation of Jak-PI3K-STAT3 pathway

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 351-364

  Choi, Bongkum ^a   Chun, Eunyoung ^a   Kim, So Yong ^a   Kim, Miyoung ^a   Lee, Ki Young ^a   Kim, Sung Joo ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GAMMA SECRETASE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR ALPHA; JANUS KINASE; JANUS KINASE 1; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STAT3 PROTEIN; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL RENEWAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; UMBILICAL CORD BLOOD;

ANIMALS; ANTIGENS, CD34; BLOOD CELLS; CELL PROLIFERATION; FETAL BLOOD; HUMANS; INTERLEUKIN-6; JANUS KINASE 1; MICE; MICE, INBRED NOD; MICE, SCID; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STEM CELLS;

EID: 83455179755     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.09.030     Document Type: Article

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