Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart

Circulation

Volumn 124, Issue 24, 2011, Pages 2702-2715

  Liu, Wei ^a   Zi, Min ^a   Naumann, Ronald ^b   Ulm, Susanne ^a   Jin, Jiawei ^a   Taglieri, Domenico M ^c   Prehar, Sukhpal ^a   Gui, Junhong ^d   Tsui, Hoyee ^a   Xiao, Rui Ping ^e   Neyses, Ludwig ^a   Solaro, R John ^c   Ke, Yunbo ^c   Cartwright, Elizabeth J ^a   Lei, Ming ^a   Wang, Xin ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e PEKING UNIVERSITY   (China)

Author keywords

cardiac hypertrophy; heart failure; signal transduction; stress

Indexed keywords

ANGIOTENSIN II; FINGOLIMOD; P21 ACTIVATED KINASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG INFUSION; DRUG MECHANISM; FEMALE; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WILD TYPE;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; DISEASE MODELS, ANIMAL; FEMALE; MALE; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; P21-ACTIVATED KINASES; PROPYLENE GLYCOLS; RATS; SIGNAL TRANSDUCTION; SPHINGOSINE; STRESS, PHYSIOLOGICAL;

EID: 83455168963     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.111.048785     Document Type: Article

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