Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload

Journal of Molecular and Cellular Cardiology

Volumn 50, Issue 4, 2011, Pages 702-711

  Liu, Wei ^a   Zi, Min ^b   Chi, Hongbo ^c   Jin, Jiawei ^a   Prehar, Sukhpal ^b   Neyses, Ludwig ^b   Cartwright, Elizabeth J ^b   Flavell, Richard A ^d   Davis, Roger J ^e   Wang, Xin ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cardiac hypertrophy; Cardiomyocyte death; Genetically modified mice; Heart failure; Signal transduction

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIAC REMODELING; CELL ASSAY; CELL DEATH; CONTROLLED STUDY; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE FUNCTION; HEART VENTRICLE OVERLOAD; LUNG CONGESTION; MALE; MECHANICAL STRESS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CARDIOMEGALY; ECHOCARDIOGRAPHY; HEART FAILURE; IMMUNOBLOTTING; IN SITU NICK-END LABELING; MAP KINASE KINASE 7; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; POLYMERASE CHAIN REACTION; PRESSURE; SIGNAL TRANSDUCTION; SUPEROXIDES; TRANSFORMING GROWTH FACTOR BETA;

MUS;

EID: 79952068475     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.01.013     Document Type: Article

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