Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Ukil, Anindita ^a   Kar, Susanta ^b   Srivastav, Supriya ^b   Ghosh, Kuntal ^a   Das, Pijush K ^b  

^a UNIVERSITY OF CALCUTTA   (India)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCYRRHETINIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; STRESS ACTIVATED PROTEIN KINASE 1; 18ALPHA GLYCYRRHETINIC ACID; 18ALPHA-GLYCYRRHETINIC ACID; CYTOKINE; DRUG DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PHOSPHOPROTEIN PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; IMMUNOMODULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PARASITE LOAD; PROTEIN DEPHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; VISCERAL LEISHMANIASIS; ANIMAL; BAGG ALBINO MOUSE; ENZYMOLOGY; LEISHMANIA DONOVANI; METABOLISM; PARASITEMIA; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; SPLEEN; TH1 CELL; UPREGULATION;

ANIMALS; CYTOKINES; GLYCYRRHETINIC ACID; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PARASITEMIA; PHOSPHOPROTEIN PHOSPHATASES; SPLEEN; TH1 CELLS; UP-REGULATION;

EID: 83355168721     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029062     Document Type: Article

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