-
1
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003;9:327-37. (Pubitemid 36109749)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.1 I
, pp. 327-337
-
-
Mendel, D.B.1
Douglas, L.A.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
Chan, E.13
Moss, K.G.14
Haznedar, J.O.15
Sukbuntherng, J.16
Blake, R.A.17
Sun, L.18
Tang, C.19
Miller, T.20
Shirazian, S.21
McMahon, G.22
Cherrington, J.M.23
more..
-
2
-
-
78650874372
-
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
-
Abrams TJ, Lee LB, Murray LJ, Pryer NK, Cherrington JM. SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer. Mol Cancer Ther 2003;2:471-8.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 471-478
-
-
Abrams, T.J.1
Lee, L.B.2
Murray, L.J.3
Pryer, N.K.4
Cherrington, J.M.5
-
3
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
DOI 10.1182/blood-2002-07-2307
-
O'Farrell AM, Abrams TJ, Yuen HA, Ngai TJ, Louie SG, Yee KW, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003;101:3597-605. (Pubitemid 36857948)
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3597-3605
-
-
O'Farrell, A.-M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.H.6
Wong, L.M.7
Hong, W.8
Lee, L.B.9
Town, A.10
Smolich, B.D.11
Manning, W.C.12
Murray, L.J.13
Heinrich, M.C.14
Cherrington, J.M.15
-
4
-
-
34548316976
-
Molecular basis for sunitinib efficacy and future clinical development
-
DOI 10.1038/nrd2380, PII NRD2380
-
Faivre S, Demetri G, Sargent W, Raymond E. Molecular basis for sunitinib efficacy and future clinical development. Nat Rev Drug Discov 2007;6:734-45. (Pubitemid 47338181)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.9
, pp. 734-745
-
-
Faivre, S.1
Demetri, G.2
Sargent, W.3
Raymond, E.4
-
5
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Rixe O, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007;356:115-24. (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
6
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Bukowski RM, Oudard S, et al. Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol 2009;27:3584-90.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, M.D.4
Bukowski, R.M.5
Oudard, S.6
-
7
-
-
76949102287
-
Health-related quality of life in patients with metastatic renal cell carcinoma treated with sunitinib vs interferon-alpha in a phase III trial: Final results and geographical analysis
-
Cella D, Michaelson MD, Bushmakin AG, Cappelleri JC, Charbonneau C, Kim ST, et al. Health-related quality of life in patients with metastatic renal cell carcinoma treated with sunitinib vs interferon-alpha in a phase III trial: final results and geographical analysis. Br J Cancer 2010;102:658-64.
-
(2010)
Br J Cancer
, vol.102
, pp. 658-664
-
-
Cella, D.1
Michaelson, M.D.2
Bushmakin, A.G.3
Cappelleri, J.C.4
Charbonneau, C.5
Kim, S.T.6
-
8
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
DOI 10.1016/S0140-6736(06)69446-4, PII S0140673606694464
-
Demetri GD, van Oosterom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, et al. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial. Lancet 2006;368:1329-38. (Pubitemid 44528723)
-
(2006)
Lancet
, vol.368
, Issue.9544
, pp. 1329-1338
-
-
Demetri, G.D.1
Van Oosterom, A.T.2
Garrett, C.R.3
Blackstein, M.E.4
Shah, M.H.5
Verweij, J.6
McArthur, G.7
Judson, I.R.8
Heinrich, M.C.9
Morgan, J.A.10
Desai, J.11
Fletcher, C.D.12
George, S.13
Bello, C.L.14
Huang, X.15
Baum, C.M.16
Casali, P.G.17
-
9
-
-
66149185085
-
-
eMC. Leatherhead (Surrey, England): Datapharm. Pfizer Limited; SUTENT, December Available from
-
eMC. Leatherhead (Surrey, England): Datapharm. Pfizer Limited; SUTENT, Summary of product characteristics; December 2010. Available from: http://www.medicines.org.uk/EMC/medicine/18531/SPC/SUTENT+12.5mg%2c+25mg%2c+37. 5mg+and+50mg+Hard+Capsules/.
-
(2010)
Summary of product characteristics
-
-
-
10
-
-
78349313440
-
I'm so tired: Biological and genetic mechanisms of cancer-related fatigue
-
GENEQOL Consortium
-
Barsevick A, Frost M, Zwinderman A, Hall P, Halyard M GENEQOL Consortium. I'm so tired: biological and genetic mechanisms of cancer-related fatigue. Qual Life Res 2010;19:1419-27.
-
(2010)
Qual Life Res
, vol.19
, pp. 1419-1427
-
-
Barsevick, A.1
Frost, M.2
Zwinderman, A.3
Hall, P.4
Halyard, M.5
-
11
-
-
55249116969
-
Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib
-
Billemont B, Medioni J, Taillade L, Helley D, Meric JB, Rixe O, et al. Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib. Br J Cancer 2008;99:1380-2.
-
(2008)
Br J Cancer
, vol.99
, pp. 1380-1382
-
-
Billemont, B.1
Medioni, J.2
Taillade, L.3
Helley, D.4
Meric, J.B.5
Rixe, O.6
-
12
-
-
33947100984
-
Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer
-
DOI 10.1038/sj.onc.1209951, PII 1209951
-
Carretero J, Medina PP, Blanco R, Smit L, Tang M, Roncador G, et al. Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer. Oncogene 2007;26:1616-25. (Pubitemid 46398737)
-
(2007)
Oncogene
, vol.26
, Issue.11
, pp. 1616-1625
-
-
Carretero, J.1
Medina, P.P.2
Blanco, R.3
Smit, L.4
Tang, M.5
Roncador, G.6
Maestre, L.7
Conde, E.8
Lopez-Rios, F.9
Clevers, H.C.10
Sanchez-Cespedes, M.11
-
13
-
-
19744365702
-
A small molecule-kinase interaction map for clinical kinase inhibitors
-
DOI 10.1038/nbt1068
-
Fabian MA, Biggs WH 3rd, Treiber DK, Atteridge CE, Azimioara MD, Benedetti MG, et al. A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 2005;23:329-36. (Pubitemid 41094421)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.3
, pp. 329-336
-
-
Fabian, M.A.1
Biggs III, W.H.2
Treiber, D.K.3
Atteridge, C.E.4
Azimioara, M.D.5
Benedetti, M.G.6
Carter, T.A.7
Ciceri, P.8
Edeen, P.T.9
Floyd, M.10
Ford, J.M.11
Galvin, M.12
Gerlach, J.L.13
Grotzfeld, R.M.14
Herrgard, S.15
Insko, D.E.16
Insko, M.A.17
Lai, A.G.18
Lelias, J.-M.19
Mehta, S.A.20
Milanov, Z.V.21
Velasco, A.M.22
Wodicka, L.M.23
Patel, H.K.24
Zarrinkar, P.P.25
Lockhart, D.J.26
more..
-
14
-
-
0035449518
-
Glucose, exercise and insulin: Emerging concepts
-
DOI 10.1111/j.1469-7793.2001.t01-2-00313.x
-
Richter EA, Derave W, Wojtaszewski JF. Glucose, exercise and insulin: emerging concepts. J Physiol 2001;535:313-22. (Pubitemid 32825671)
-
(2001)
Journal of Physiology
, vol.535
, Issue.2
, pp. 313-322
-
-
Richter, E.A.1
Derave, W.2
Wojtaszewski, J.F.P.3
-
15
-
-
66149142809
-
Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis
-
Lahdenranta J, Hagendoorn J, Padera TP, Hoshida T, Nelson G, Kashiwagi S, et al. Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. Cancer Res 2009;69:2801-8.
-
(2009)
Cancer Res
, vol.69
, pp. 2801-2808
-
-
Lahdenranta, J.1
Hagendoorn, J.2
Padera, T.P.3
Hoshida, T.4
Nelson, G.5
Kashiwagi, S.6
-
16
-
-
34250192263
-
Symptom clusters in cancer patients and their relation to EGFR ligand modulation of the circadian axis
-
discussion 176-7
-
Rich TA. Symptom clusters in cancer patients and their relation to EGFR ligand modulation of the circadian axis. J Support Oncol 2007;5:167-74, discussion 176-7.
-
(2007)
J Support Oncol
, vol.5
, pp. 167-174
-
-
Rich, T.A.1
-
17
-
-
16344373564
-
Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer
-
DOI 10.1158/1078-0432.CCR-04-2000
-
Rich T, Innominato PF, Boerner J, Mormont MC, Iacobelli S, Baron B, et al. Elevated serum cytokines correlated with altered behavior, serum cortisol rhythm, and dampened 24-hour rest-activity patterns in patients with metastatic colorectal cancer. Clin Cancer Res 2005;11:1757-64. (Pubitemid 40471837)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.5
, pp. 1757-1764
-
-
Rich, T.1
Innominato, P.F.2
Boerner, J.3
Mormont, M.C.4
Iacobelli, S.5
Baron, B.6
Jasmin, C.7
Levi, F.8
-
18
-
-
44449171930
-
Dermatological reactions to the multitargeted tyrosine kinase inhibitor sunitinib
-
Rosenbaum SE, Wu S, Newman MA, West DP, Kuzel T, Lacouture ME. Dermatological reactions to the multitargeted tyrosine kinase inhibitor sunitinib. Support Care Cancer 2008;16:557-66.
-
(2008)
Support Care Cancer
, vol.16
, pp. 557-566
-
-
Rosenbaum, S.E.1
Wu, S.2
Newman, M.A.3
West, D.P.4
Kuzel, T.5
Lacouture, M.E.6
-
19
-
-
0142241307
-
Hair Depigmentation is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
-
DOI 10.1124/jpet.103.052530
-
Moss KG, Toner GC, Cherrington JM, Mendel DB, Laird AD. Hair depigmentation is a biological readout for pharmacological inhibition of KIT in mice and humans. J Pharmacol Exp Ther 2003;307:476-80. (Pubitemid 37310659)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.2
, pp. 476-480
-
-
Moss, K.G.1
Toner, G.C.2
Cherrington, J.M.3
Mendel, D.B.4
Laird, A.D.5
-
21
-
-
33747416695
-
Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity
-
DOI 10.1161/CIRCULATIONAHA.106.639831, PII 0000301720060815000007
-
Hsieh PC, MacGillivray C, Gannon J, Cruz FU, Lee RT. Local controlled intramyocardial delivery of platelet-derived growth factor improves postinfarction ventricular function without pulmonary toxicity. Circulation 2006;114:637-44. (Pubitemid 44252305)
-
(2006)
Circulation
, vol.114
, Issue.7
, pp. 637-644
-
-
Hsieh, P.C.H.1
MacGillivray, C.2
Gannon, J.3
Cruz, F.U.4
Lee, R.T.5
-
22
-
-
28244446238
-
Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse
-
DOI 10.1016/j.jacc.2005.08.045, PII S0735109705022047
-
Kido M, Du L, Sullivan CC, Li X, Deutsch R, Jamieson SW, et al. Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol 2005;46:2116-24. (Pubitemid 41713601)
-
(2005)
Journal of the American College of Cardiology
, vol.46
, Issue.11
, pp. 2116-2124
-
-
Kido, M.1
Du, L.2
Sullivan, C.C.3
Li, X.4
Deutsch, R.5
Jamieson, S.W.6
Thistlethwaite, P.A.7
-
23
-
-
33646149385
-
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload
-
DOI 10.1161/01.HYP.0000215207.54689.31, PII 0000426820060500000018
-
Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension 2006;47:887-93. (Pubitemid 44297560)
-
(2006)
Hypertension
, vol.47
, Issue.5
, pp. 887-893
-
-
Izumiya, Y.1
Shiojima, I.2
Sato, K.3
Sawyer, D.B.4
Colucci, W.S.5
Walsh, K.6
-
24
-
-
34247480545
-
Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition
-
DOI 10.1038/nrc2106, PII NRC2106
-
Force T, Krause DS, Van Etten RA. Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition. Nat Rev Cancer 2007;7:332-44. (Pubitemid 46652481)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.5
, pp. 332-344
-
-
Force, T.1
Krause, D.S.2
Van Etten, R.A.3
-
25
-
-
57349174523
-
Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib
-
Hasinoff BB, Patel D, O'Hara KA. Mechanisms of myocyte cytotoxicity induced by the multiple receptor tyrosine kinase inhibitor sunitinib. Mol Pharmacol 2008;74:1722-8.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1722-1728
-
-
Hasinoff, B.B.1
Patel, D.2
O'Hara, K.A.3
-
26
-
-
36849023013
-
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
-
DOI 10.1016/S0140-6736(07)61865-0, PII S0140673607618650
-
Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, et al. Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib. Lancet 2007;370:2011-9. (Pubitemid 350236338)
-
(2007)
Lancet
, vol.370
, Issue.9604
, pp. 2011-2019
-
-
Chu, T.F.1
Rupnick, M.A.2
Kerkela, R.3
Dallabrida, S.M.4
Zurakowski, D.5
Nguyen, L.6
Woulfe, K.7
Pravda, E.8
Cassiola, F.9
Desai, J.10
George, S.11
Morgan, J.A.12
Harris, D.M.13
Ismail, N.S.14
Chen, J.-H.15
Schoen, F.J.16
Van Den, A.A.D.17
Demetri, G.D.18
Force, T.19
Chen, M.H.20
more..
-
27
-
-
54349127397
-
Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells
-
Will Y, Dykens JA, Nadanaciva S, Hirakawa B, Jamieson J, Marroquin LD, et al. Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells. Toxicol Sci 2008;106:153-61.
-
(2008)
Toxicol Sci
, vol.106
, pp. 153-161
-
-
Will, Y.1
Dykens, J.A.2
Nadanaciva, S.3
Hirakawa, B.4
Jamieson, J.5
Marroquin, L.D.6
-
28
-
-
48349122489
-
The clinical implications of sunitinib-induced hypothyroidism: A prospective evaluation
-
Wolter P, Stefan C, Decallonne B, Dumez H, Bex M, Carmeliet P, et al. The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. Br J Cancer 2008;99:448-54.
-
(2008)
Br J Cancer
, vol.99
, pp. 448-454
-
-
Wolter, P.1
Stefan, C.2
Decallonne, B.3
Dumez, H.4
Bex, M.5
Carmeliet, P.6
-
29
-
-
34547865714
-
Vascular endothelial growth factor (VEGF), VEGF receptors expression and microvascular density in benign and malignant thyroid diseases
-
DOI 10.1111/j.1365-2613.2007.00533.x
-
Jebreel A, England J, Bedford K, Murphy J, Karsai L, Atkin S. Vascular endothelial growth factor (VEGF), VEGF receptors expression and microvascular density in benign and malignant thyroid diseases. Int J Exp Pathol 2007;88:271-7. (Pubitemid 47256303)
-
(2007)
International Journal of Experimental Pathology
, vol.88
, Issue.4
, pp. 271-277
-
-
Jebreel, A.1
England, J.2
Bedford, K.3
Murphy, J.4
Karsai, L.5
Atkin, S.6
-
30
-
-
33745982267
-
Iodide inhibits vascular endothelial growth factor-A expression in cultured human thyroid follicles: A microarray search for effects of thyrotropin and iodide on angiogenesis factors
-
DOI 10.1089/thy.2006.16.545
-
Yamada E, Yamazaki K, Takano K, Obara T, Sato K. Iodide inhibits vascular endothelial growth factor-A expression in cultured human thyroid follicles: a microarray search for effects of thyrotropin and iodide on angiogenesis factors. Thyroid 2006;16:545-54. (Pubitemid 44066261)
-
(2006)
Thyroid
, vol.16
, Issue.6
, pp. 545-554
-
-
Yamada, E.1
Yamazaki, K.2
Takano, K.3
Obara, T.4
Sato, K.5
-
31
-
-
34548764576
-
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
-
DOI 10.1210/jc.2007-0586
-
Mannavola D, Coco P, Vannucchi G, Bertuelli R, Carletto M, Casali PG, et al. A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. J Clin Endocrinol Metab 2007;92:3531-4. (Pubitemid 47435331)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.9
, pp. 3531-3534
-
-
Mannavola, D.1
Coco, P.2
Vannucchi, G.3
Bertuelli, R.4
Carletto, M.5
Casali, P.G.6
Beck-Peccoz, P.7
Fugazzola, L.8
-
32
-
-
33750961647
-
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors
-
Desai J, Yassa L, Marqusee E, George S, Frates MC, Chen MH, et al. Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Ann Intern Med 2006;145:660-4. (Pubitemid 46768841)
-
(2006)
Annals of Internal Medicine
, vol.145
, Issue.9
, pp. 660-664
-
-
Desai, J.1
Yassa, L.2
Marqusee, E.3
George, S.4
Frates, M.C.5
Chen, M.H.6
Morgan, J.A.7
Dychter, S.S.8
Larsen, P.R.9
Demetri, G.D.10
Alexander, E.K.11
-
33
-
-
34248632840
-
Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
-
Wong E, Rosen LS, Mulay M, Vanvugt A, Dinolfo M, Tomoda C, et al. Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid 2007;17:351-5.
-
(2007)
Thyroid
, vol.17
, pp. 351-355
-
-
Wong, E.1
Rosen, L.S.2
Mulay, M.3
Vanvugt, A.4
Dinolfo, M.5
Tomoda, C.6
-
34
-
-
77649310826
-
Sunitinib induces hypothyroidism with a markedly reduced vascularity
-
Makita N, Miyakawa M, Fujita T, Iiri T. Sunitinib induces hypothyroidism with a markedly reduced vascularity. Thyroid 2010;20:323-6.
-
(2010)
Thyroid
, vol.20
, pp. 323-326
-
-
Makita, N.1
Miyakawa, M.2
Fujita, T.3
Iiri, T.4
-
35
-
-
10344258027
-
Thyrotropin (TSH)-induced production of vascular endothelial growth factor in thyroid cancer cells in vitro: Evaluation of TSH signal transduction and of angiogenesis-stimulating growth factors
-
DOI 10.1210/jc.2004-1260
-
Hoffmann S, Hofbauer LC, Scharrenbach V, Wunderlich A, Hassan I, Lingelbach S, et al. Thyrotropin (TSH)-induced production of vascular endothelial growth factor in thyroid cancer cells in vitro: evaluation of TSH signal transduction and of angiogenesis-stimulating growth factors. J Clin Endocrinol Metab 2004;89:6139-45. (Pubitemid 39628426)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.12
, pp. 6139-6145
-
-
Hoffmann, S.1
Hofbauer, L.C.2
Scharrenbach, V.3
Wunderlich, A.4
Hassan, I.5
Lingelbach, S.6
Zielke, A.7
-
36
-
-
46349101365
-
Effect of sunitinib on growth and function of FRTL-5 thyroid cells
-
DOI 10.1089/thy.2007.0336
-
Salem AK, Fenton MS, Marion KM, Hershman JM. Effect of sunitinib on growth and function of FRTL-5 thyroid cells. Thyroid 2008;18:631-5. (Pubitemid 351918450)
-
(2008)
Thyroid
, vol.18
, Issue.6
, pp. 631-635
-
-
Salem, A.K.1
Fenton, M.S.2
Marion, K.M.3
Hershman, J.M.4
-
37
-
-
33749544080
-
An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases
-
DOI 10.1210/jc.2005-2845
-
Kim DW, Jo YS, Jung HS, Chung HK, Song JH, Park KC, et al. An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases. J Clin Endocrinol Metab 2006;91:4070-6. (Pubitemid 44536887)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.10
, pp. 4070-4076
-
-
Dong, W.K.1
Young, S.J.2
Hye, S.J.3
Hyo, K.C.4
Jung, H.S.5
Ki, C.P.6
Su, H.P.7
Jung, H.H.8
So, Y.R.9
Gi, R.K.10
Lee, S.-J.11
Jo, K.-W.12
Shong, M.13
-
38
-
-
0034693757
-
The RET proto-oncogene in human cancers
-
Jhiang SM. The RET proto-oncogene in human cancers. Oncogene 2000;19:5590-7.
-
(2000)
Oncogene
, vol.19
, pp. 5590-5597
-
-
Jhiang, S.M.1
-
39
-
-
83355174394
-
Efficacy and thyroidal effects of sunitinib in Japanese patients with metastatic renal cell carcinoma: Hypothyroidism and thyroid atrophy as potential biomarkers for sunitinib?
-
Shinohara N, Takahashi T, Kamishima H, Ikushima H, Sazawa A, Kanayama H. Efficacy and thyroidal effects of sunitinib in Japanese patients with metastatic renal cell carcinoma: Hypothyroidism and thyroid atrophy as potential biomarkers for sunitinib? J Clin Oncol 2009;27:e16097.
-
(2009)
J Clin Oncol
, vol.27
-
-
Shinohara, N.1
Takahashi, T.2
Kamishima, H.3
Ikushima, H.4
Sazawa, A.5
Kanayama, H.6
-
40
-
-
77956372429
-
Hypothyroidism and survival during sunitinib therapy in metastatic renal cell cancer: A prospective observational analysis
-
Abstract 317
-
Sabatier R, Gravis G, Deville J, Salem N, Brunelle S, Walz J. Hypothyroidism and survival during sunitinib therapy in metastatic renal cell cancer: A prospective observational analysis. American Society for Clinical Oncology 2009 Genitourinary Cancers Symposium 2009; Abstract 317.
-
American Society for Clinical Oncology 2009 Genitourinary Cancers Symposium 2009
-
-
Sabatier, R.1
Gravis, G.2
Deville, J.3
Salem, N.4
Brunelle, S.5
Walz, J.6
-
41
-
-
77958063197
-
Hypertension (HTN) as a biomarker of efficacy in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib
-
Alexandria (VA): ASCO; Abstract nr 312
-
Rini BI, Cohen DP, Lu D, Chen I, Hariharan S, Gore ME, et al. Hypertension (HTN) as a biomarker of efficacy in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib. In: Proceedings of the American Society for Clinical Oncology 2010 Genitourinary Cancers Symposium 2010 Mar 5-7; San Francisco. Alexandria (VA): ASCO; 2010. Abstract nr 312.
-
(2010)
Proceedings of the American Society for Clinical Oncology 2010 Genitourinary Cancers Symposium 2010 Mar 5-7; San Francisco
-
-
Rini, B.I.1
Cohen, D.P.2
Lu, D.3
Chen, I.4
Hariharan, S.5
Gore, M.E.6
-
42
-
-
77649125649
-
Diastolic blood pressure (dBP) and pharmacokinetics (PK) as predictors of axitinib efficacy in metastatic renal cell cancer (mRCC)
-
Rixe O, Dutcher J, Motzer R, Wilding G, Stadler WM, Garrett M, et al. Diastolic blood pressure (dBP) and pharmacokinetics (PK) as predictors of axitinib efficacy in metastatic renal cell cancer (mRCC). J Clin Oncol 2009;27:5045.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5045
-
-
Rixe, O.1
Dutcher, J.2
Motzer, R.3
Wilding, G.4
Stadler, W.M.5
Garrett, M.6
-
43
-
-
0031943236
-
VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells
-
Hood JD, Meininger CJ, Ziche M, Granger HJ. VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells. Am J Physiol 1998;274:H1054-8.
-
(1998)
Am J Physiol
, vol.274
-
-
Hood, J.D.1
Meininger, C.J.2
Ziche, M.3
Granger, H.J.4
-
45
-
-
21344462378
-
Cutaneous side-effects of kinase inhibitors and blocking antibodies
-
DOI 10.1016/S1470-2045(05)70243-6, PII S1470204505702436
-
Robert C, Soria JC, Spatz A, Le Cesne A, Malka D, Pautier P, et al. Cutaneous side-effects of kinase inhibitors and blocking antibodies. Lancet Oncol 2005;6:491-500. (Pubitemid 40903630)
-
(2005)
Lancet Oncology
, vol.6
, Issue.7
, pp. 491-500
-
-
Robert, C.1
Soria, J.-C.2
Spatz, A.3
Le, C.A.4
Malka, D.5
Pautier, P.6
Wechsler, J.7
Lhomme, C.8
Escudier, B.9
Boige, V.10
Armand, J.-P.11
Le, C.T.12
-
46
-
-
0029129814
-
Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells
-
Detmar M, Yeo KT, Nagy JA, Van de Water L, Brown LF, Berse B, et al. Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells. J Invest Dermatol 1995;105:44-50.
-
(1995)
J Invest Dermatol
, vol.105
, pp. 44-50
-
-
Detmar, M.1
Yeo, K.T.2
Nagy, J.A.3
Van De Water, L.4
Brown, L.F.5
Berse, B.6
-
47
-
-
2442636729
-
Loss of vascular endothelial growth factor A activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation
-
DOI 10.1158/0008-5472.CAN-03-2581
-
Rossiter H, Barresi C, Pammer J, Rendl M, Haigh J, Wagner EF, et al. Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Res 2004;64:3508-16. (Pubitemid 38657925)
-
(2004)
Cancer Research
, vol.64
, Issue.10
, pp. 3508-3516
-
-
Rossiter, H.1
Barresi, C.2
Pammer, J.3
Rendl, M.4
Haigh, J.5
Wagner, E.F.6
Tschachler, E.7
-
48
-
-
27544485277
-
Novel function for vascular endothelial growth factor receptor-1 on epidermal keratinocytes
-
Wilgus TA, Matthies AM, Radek KA, Dovi JV, Burns AL, Shankar R, et al. Novel function for vascular endothelial growth factor receptor-1 on epidermal keratinocytes. Am J Pathol 2005;167:1257-66. (Pubitemid 41541412)
-
(2005)
American Journal of Pathology
, vol.167
, Issue.5
, pp. 1257-1266
-
-
Wilgus, T.A.1
Matthies, A.M.2
Radek, K.A.3
Dovi, J.V.4
Burns, A.L.5
Shankar, R.6
DiPietro, L.A.7
-
49
-
-
0029001001
-
Production and secretion of platelet-derived growth factor AB by cultured human keratinocytes: Regulatory effects of phorbol 12-myristate 13-acetate, etretinate, 1,25-dihydroxyvitamin D3, and several cytokines
-
Zhang JZ, Maruyama K, Ono I, Kaneko F. Production and secretion of platelet-derived growth factor AB by cultured human keratinocytes: regulatory effects of phorbol 12-myristate 13-acetate, etretinate, 1,25-dihydroxyvitamin D3, and several cytokines. J Dermatol 1995;22:305-9.
-
(1995)
J Dermatol
, vol.22
, pp. 305-309
-
-
Zhang, J.Z.1
Maruyama, K.2
Ono, I.3
Kaneko, F.4
-
50
-
-
38449097166
-
Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma
-
de Böuard S, Herlin P, Christensen JG, Lemoisson E, Gauduchon P, Raymond E, et al. Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma. Neuro-oncol 2007;9:412-23.
-
(2007)
Neuro-oncol
, vol.9
, pp. 412-423
-
-
De Böuard, S.1
Herlin, P.2
Christensen, J.G.3
Lemoisson, E.4
Gauduchon, P.5
Raymond, E.6
-
51
-
-
52049106205
-
The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway
-
Roodhart JM, Langenberg MH, Witteveen E, Voest EE. The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway. Curr Clin Pharmacol 2008;3:132-43.
-
(2008)
Curr Clin Pharmacol
, vol.3
, pp. 132-143
-
-
Roodhart, J.M.1
Langenberg, M.H.2
Witteveen, E.3
Voest, E.E.4
-
52
-
-
0026586055
-
Role of c-kit ligand in the expansion of human hematopoietic progenitor cells
-
Brandt J, Briddell RA, Srour EF, Leemhuis TB, Hoffman R. Role of c-kit ligand in the expansion of human hematopoietic progenitor cells. Blood 1992;79:634-41.
-
(1992)
Blood
, vol.79
, pp. 634-641
-
-
Brandt, J.1
Briddell, R.A.2
Srour, E.F.3
Leemhuis, T.B.4
Hoffman, R.5
-
53
-
-
34848922067
-
Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome [3]
-
DOI 10.1093/annonc/mdm454
-
Kapiteijn E, Brand A, Kroep J, Gelderblom H. Sunitinib induced hypertension, thrombotic microangiopathy and reversible posterior leukencephalopathy syndrome. Ann Oncol 2007;18:1745-7. (Pubitemid 47506266)
-
(2007)
Annals of Oncology
, vol.18
, Issue.10
, pp. 1745-1747
-
-
Kapiteijn, E.1
Brand, A.2
Kroep, J.3
Gelderblom, H.4
-
54
-
-
54349087074
-
Drug-induced immune thrombocytopenic purpura secondary to sunitinib
-
Trinkaus M, Trudeau M, Callum J. Drug-induced immune thrombocytopenic purpura secondary to sunitinib. Curr Oncol 2008;15:152-4.
-
(2008)
Curr Oncol
, vol.15
, pp. 152-154
-
-
Trinkaus, M.1
Trudeau, M.2
Callum, J.3
-
55
-
-
0032400862
-
Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
-
Gabrilovich D, Ishida T, Oyama T, Ran S, Kravtsov V, Nadaf S, et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 1998;92:4150-66. (Pubitemid 28544331)
-
(1998)
Blood
, vol.92
, Issue.11
, pp. 4150-4166
-
-
Gabrilovich, D.1
Ishida, T.2
Oyama, T.3
Ran, S.4
Kravtsov, V.5
Nadaf, S.6
Carbone, D.P.7
-
56
-
-
77649233144
-
Sunitinib impairs the proliferation and function of human peripheral T cell and prevents T-cell-mediated immune response in mice
-
Gu Y, Zhao W, Meng F, Qu B, Zhu X, Sun Y, et al. Sunitinib impairs the proliferation and function of human peripheral T cell and prevents T-cell-mediated immune response in mice. Clin Immunol 2010;135:55-62.
-
(2010)
Clin Immunol
, vol.135
, pp. 55-62
-
-
Gu, Y.1
Zhao, W.2
Meng, F.3
Qu, B.4
Zhu, X.5
Sun, Y.6
-
57
-
-
47049127786
-
Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses
-
Hipp MM, Hilf N, Walter S, Werth D, Brauer KM, Radsak MP, et al. Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood 2008;111:5610-20.
-
(2008)
Blood
, vol.111
, pp. 5610-5620
-
-
Hipp, M.M.1
Hilf, N.2
Walter, S.3
Werth, D.4
Brauer, K.M.5
Radsak, M.P.6
-
58
-
-
39549091069
-
VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma
-
DOI 10.1084/jem.20072041
-
Maharaj AS, Walshe TE, Saint-Geniez M, Venkatesha S, Maldonado AE, Himes NC, et al. VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma. J Exp Med 2008;205:491-501. (Pubitemid 351281612)
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.2
, pp. 491-501
-
-
Maharaj, A.S.R.1
Walshe, T.E.2
Saint-Geniez, M.3
Venkatesha, S.4
Maldonado, A.E.5
Himes, N.C.6
Matharu, K.S.7
Ananth, K.S.8
D'Amore, P.A.9
-
59
-
-
37349055147
-
High Frequency of Intracerebral Hemorrhage in Metastatic Renal Carcinoma Patients with Brain Metastases Treated with Tyrosine Kinase Inhibitors Targeting the Vascular Endothelial Growth Factor Receptor
-
DOI 10.1016/j.eururo.2007.08.053, PII S0302283807011360
-
Pouessel D, Culine S. High frequency of intracerebral hemorrhage in metastatic renal carcinoma patients with brain metastases treated with tyrosine kinase inhibitors targeting the vascular endothelial growth factor receptor. Eur Urol 2008;53:376-81. (Pubitemid 350296582)
-
(2008)
European Urology
, vol.53
, Issue.2
, pp. 376-381
-
-
Pouessel, D.1
Culine, S.2
-
60
-
-
43649098164
-
Systemic Diseases with Renal Manifestations
-
DOI 10.1016/j.pop.2008.01.006, PII S0095454308000080
-
Rajashekar A, Perazella MA, Crowley S. Systemic diseases with renal manifestations. Prim Care 2008;35:297-328, vi-vii. (Pubitemid 351681912)
-
(2008)
Primary Care - Clinics in Office Practice
, vol.35
, Issue.2
, pp. 297-328
-
-
Rajashekar, A.1
Perazella, M.A.2
Crowley, S.3
-
61
-
-
38449087414
-
The role of the EGFR signaling in tumor microenvironment
-
DOI 10.1002/jcp.21260
-
De Luca A, Carotenuto A, Rachiglio A, Gallo M, Maiello MR, Aldinucci D, et al. The role of the EGFR signaling in tumor microenvironment. J Cell Physiol 2008;214:559-67. (Pubitemid 351224199)
-
(2008)
Journal of Cellular Physiology
, vol.214
, Issue.3
, pp. 559-567
-
-
De Luca, A.1
Carotenuto, A.2
Rachiglio, A.3
Gallo, M.4
Maiello, M.R.5
Aldinucci, D.6
Pinto, A.7
Normanno, N.8
-
62
-
-
50349101200
-
Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor
-
Steeghs N, Gelderblom H, Roodt JO, Christensen O, Rajagopalan P, Hovens M, et al. Hypertension and rarefaction during treatment with telatinib, a small molecule angiogenesis inhibitor. Clin Cancer Res 2008;14:3470-6.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3470-3476
-
-
Steeghs, N.1
Gelderblom, H.2
Roodt, J.O.3
Christensen, O.4
Rajagopalan, P.5
Hovens, M.6
-
63
-
-
69249142285
-
ABT-869, a promising multitargeted tyrosine kinase inhibitor: From bench to bedside
-
Zhou J, Goh BC, Albert DH, Chen CS. ABT-869, a promising multitargeted tyrosine kinase inhibitor: from bench to bedside. J Hematol Oncol 2009;2:33.
-
(2009)
J Hematol Oncol
, vol.2
, pp. 33
-
-
Zhou, J.1
Goh, B.C.2
Albert, D.H.3
Chen, C.S.4
-
64
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, et al. TARGET Study Group. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007;356:125-34. (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
65
-
-
77952300540
-
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
-
Escudier B, Bellmunt J, Négrier S, Bajetta E, Melichar B, Bracarda S, et al. Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol 2010;28:2144-50.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2144-2150
-
-
Escudier, B.1
Bellmunt, J.2
Négrier, S.3
Bajetta, E.4
Melichar, B.5
Bracarda, S.6
-
66
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes G, Carducci M, Tomczak P, Dutcher J, Figlin R, Kapoor A, et al. Global ARCC Trial. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007;356:2271-81. (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
67
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
RECORD-1 Study Group
-
Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. RECORD-1 Study Group. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 2008;372:449-56.
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
Hutson, T.E.4
Porta, C.5
Bracarda, S.6
-
68
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, Szczylik C, Lee E, Wagstaff J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010;28:1061-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
Szczylik, C.4
Lee, E.5
Wagstaff, J.6
-
69
-
-
34447322566
-
Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity
-
DOI 10.1158/1535-7163.MCT-07-0193
-
Kumar R, Knick VB, Rudolph SK, Johnson JH, Crosby RM, Crouthamel MC, et al. Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity. Mol Cancer Ther 2007;6:2012-21. (Pubitemid 47052491)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.7
, pp. 2012-2021
-
-
Kumar, R.1
Knick, V.B.2
Rudolph, S.K.3
Johnson, J.H.4
Crosby, R.M.5
Crouthamel, M.-C.6
Hopper, T.M.7
Miller, C.G.8
Harrington, L.E.9
Onori, J.A.10
Mullin, R.J.11
Gilmer, T.M.12
Truesdale, A.T.13
Epperly, A.H.14
Boloor, A.15
Stafford, J.A.16
Luttrell, D.K.17
Cheung, M.18
-
70
-
-
77953757715
-
Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma
-
Schmidinger M, Bellmunt J. Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma. Cancer Treat Rev 2010;36:416-24.
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 416-424
-
-
Schmidinger, M.1
Bellmunt, J.2
-
71
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109. (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
72
-
-
77649168107
-
Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: What are the important clinical markers to target?
-
Vaklavas C, Lenihan D, Kurzrock R, Tsimberidou AM. Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target? Oncologist 2010;15:130-41.
-
(2010)
Oncologist
, vol.15
, pp. 130-141
-
-
Vaklavas, C.1
Lenihan, D.2
Kurzrock, R.3
Tsimberidou, A.M.4
-
73
-
-
77955240423
-
Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib
-
Jain L, Sissung TM, Danesi R, Kohn EC, Dahut WL, Kummar S, et al. Hypertension and hand-foot skin reactions related to VEGFR2 genotype and improved clinical outcome following bevacizumab and sorafenib. J Exp Clin Cancer Res 2010;29:95.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 95
-
-
Jain, L.1
Sissung, T.M.2
Danesi, R.3
Kohn, E.C.4
Dahut, W.L.5
Kummar, S.6
-
74
-
-
80052225008
-
Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial
-
abstr 4503
-
Rini BI, Escudier B, Tomczak P, Kaprin A, Hutson TE, Szczylik C, et al. Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial. J Clin Oncol 2011;29(suppl; abstr 4503).
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Rini, B.I.1
Escudier, B.2
Tomczak, P.3
Kaprin, A.4
Hutson, T.E.5
Szczylik, C.6
-
75
-
-
77953033291
-
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis
-
Houk BE, Bello CL, Poland B, Rosen LS, Demetri GD, Motzer RJ. Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. Cancer Chemother Pharmacol 2010;66:357-71.
-
(2010)
Cancer Chemother Pharmacol
, vol.66
, pp. 357-371
-
-
Houk, B.E.1
Bello, C.L.2
Poland, B.3
Rosen, L.S.4
Demetri, G.D.5
Motzer, R.J.6
|