Mouse studies to shape clinical trials for mitochondrial diseases: High fat diet in Harlequin mice

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Schiff, Manuel ^a,b,c   Bénit, Paule ^a,b   El Khoury, Riyad ^a,b   Schlemmer, Dimitri ^c   Benoist, Jean François ^a,c   Rustin, Pierre ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CARNITINE; GLUCOSE; GLUTAMINE; PALMITIC ACID; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; PALMITIC ACID DERIVATIVE;

ALOPECIA; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CELL STRAIN; CEREBELLUM ATROPHY; CONTROLLED STUDY; CULTURE MEDIUM; DIET SUPPLEMENTATION; DIETARY INTAKE; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FIBROBLAST; FOOD COMPOSITION; GENE; GENE DELETION; HUMAN; HUMAN CELL; LIPID DIET; NDUFS1 GENE; NDUFS4 GENE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN DEFICIENCY; ANIMAL; ATROPHY; CATTLE; CELL DEATH; CELL RESPIRATION; CEREBELLUM; CLINICAL TRIAL (TOPIC); DRUG EFFECT; ELECTRON TRANSPORT; MITOCHONDRIAL COMPLEX I DEFICIENCY; MOUSE; MOUSE MUTANT; OXIDATION REDUCTION REACTION; PATHOLOGY; PHENOTYPE; ROTAROD TEST;

ANIMALS; ATROPHY; CARNITINE; CATTLE; CELL DEATH; CELL RESPIRATION; CEREBELLUM; CLINICAL TRIALS AS TOPIC; CYTOPROTECTION; DIET, HIGH-FAT; DISEASE PROGRESSION; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; FIBROBLASTS; HUMANS; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL DISEASES; NERVE DEGENERATION; OXIDATION-REDUCTION; PALMITATES; PHENOTYPE; ROTAROD PERFORMANCE TEST; SERUM ALBUMIN, BOVINE; SUCCINIC ACID;

EID: 83255164009     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028823     Document Type: Article

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