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Volumn 5, Issue , 2011, Pages

Noise filtering tradeoffs in spatial gradient sensing and cell polarization response

Author keywords

Noise gradient sensing g protein cell; Polarity yeast mating

Indexed keywords

EUKARYOTA;

EID: 83255162690     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-5-196     Document Type: Article
Times cited : (22)

References (57)
  • 1
    • 0037078982 scopus 로고    scopus 로고
    • Control, exploitation, and tolerance of intracellular noise
    • 10.1038/nature01258, 12432408
    • Rao CV, Wolf DM, Arkin AP. Control, exploitation, and tolerance of intracellular noise. Nature 2002, 420:231-237. 10.1038/nature01258, 12432408.
    • (2002) Nature , vol.420 , pp. 231-237
    • Rao, C.V.1    Wolf, D.M.2    Arkin, A.P.3
  • 2
    • 34548612846 scopus 로고    scopus 로고
    • Biased random walk by stochastic fluctuations of chemoattractant-receptor interactions at the lower limit of detection
    • 10.1529/biophysj.107.104356, 1948060, 17513372
    • van Haastert PJM, Postma M. Biased random walk by stochastic fluctuations of chemoattractant-receptor interactions at the lower limit of detection. Biophys J 2007, 93:1787-1796. 10.1529/biophysj.107.104356, 1948060, 17513372.
    • (2007) Biophys J , vol.93 , pp. 1787-1796
    • van Haastert, P.J.M.1    Postma, M.2
  • 5
    • 0017664223 scopus 로고
    • Physics of chemoreception
    • 10.1016/S0006-3495(77)85544-6, 1473391, 911982
    • Berg HC, Purcell EM. Physics of chemoreception. Biophys J 1977, 20:193-219. 10.1016/S0006-3495(77)85544-6, 1473391, 911982.
    • (1977) Biophys J , vol.20 , pp. 193-219
    • Berg, H.C.1    Purcell, E.M.2
  • 6
    • 22544467427 scopus 로고    scopus 로고
    • Physical limits to biochemical signaling
    • 10.1073/pnas.0504321102, 1177398, 16006514
    • Bialek W, Setayeshgar S. Physical limits to biochemical signaling. Proc Natl Acad Sci USA 2005, 102:10040-10045. 10.1073/pnas.0504321102, 1177398, 16006514.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10040-10045
    • Bialek, W.1    Setayeshgar, S.2
  • 7
    • 33751396142 scopus 로고    scopus 로고
    • Optimal noise filtering in the chemotactic response of E. coli
    • Andrews BW, Yi T-M, Iglesias PA. Optimal noise filtering in the chemotactic response of E. coli. PLoS Comp Biol 2006, 2.
    • (2006) PLoS Comp Biol , vol.2
    • Andrews, B.W.1    Yi, T.-.M.2    Iglesias, P.A.3
  • 8
    • 85010384444 scopus 로고
    • Cambridge, UK: Cambridge University Press
    • Thompson DW. On Growth and Form 1961, Cambridge, UK: Cambridge University Press.
    • (1961) On Growth and Form
    • Thompson, D.W.1
  • 9
    • 0030045345 scopus 로고    scopus 로고
    • Origins of cell polarity
    • 10.1016/S0092-8674(00)81278-7, 8608587
    • Drubin DG, Nelson WJ. Origins of cell polarity. Cell 1996, 84:335-344. 10.1016/S0092-8674(00)81278-7, 8608587.
    • (1996) Cell , vol.84 , pp. 335-344
    • Drubin, D.G.1    Nelson, W.J.2
  • 10
    • 0032823984 scopus 로고    scopus 로고
    • Orientation of chemotactic cells and growth cones: Models and mechanisms
    • Meinhardt H. Orientation of chemotactic cells and growth cones: Models and mechanisms. J Cell Sci 1999, 112:2867-2874.
    • (1999) J Cell Sci , vol.112 , pp. 2867-2874
    • Meinhardt, H.1
  • 11
    • 34249865356 scopus 로고    scopus 로고
    • Modeling yeast cell polarization induced by pheromone gradients
    • Yi T-M, Chen S, Chou C-S, Nie Q. Modeling yeast cell polarization induced by pheromone gradients. J Stat Phys 2007, 128:193-207.
    • (2007) J Stat Phys , vol.128 , pp. 193-207
    • Yi, T.-.M.1    Chen, S.2    Chou, C.-.S.3    Nie, Q.4
  • 12
    • 52149120381 scopus 로고    scopus 로고
    • Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients
    • 10.1371/journal.pone.0003103, 3021495, 21267054
    • Chou C-S, Nie Q, Yi T-M. Modeling robustness tradeoffs in yeast cell polarization induced by spatial gradients. PLoS ONE 2008, 3:e3103. 10.1371/journal.pone.0003103, 3021495, 21267054.
    • (2008) PLoS ONE , vol.3
    • Chou, C.-.S.1    Nie, Q.2    Yi, T.-.M.3
  • 13
    • 12244257806 scopus 로고    scopus 로고
    • Noisy signal amplification in ultrasensitive signal transduction
    • 10.1073/pnas.0403350102, 544281, 15625116
    • Shibata T, Fujimoto K. Noisy signal amplification in ultrasensitive signal transduction. Proc Natl Acad Sci USA 2005, 102:331-336. 10.1073/pnas.0403350102, 544281, 15625116.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 331-336
    • Shibata, T.1    Fujimoto, K.2
  • 14
    • 0034002965 scopus 로고    scopus 로고
    • Polarization of cell growth in yeast: I. Establishment and maintenance of polarity states
    • Pruyne D, Bretscher A. Polarization of cell growth in yeast: I. Establishment and maintenance of polarity states. J Cell Sci 2000, 113:365-375.
    • (2000) J Cell Sci , vol.113 , pp. 365-375
    • Pruyne, D.1    Bretscher, A.2
  • 15
    • 0034056057 scopus 로고    scopus 로고
    • Polarization of cell growth in yeast: II. The role of the cortical actin cytoskeleton
    • Pruyne D, Bretscher A. Polarization of cell growth in yeast: II. The role of the cortical actin cytoskeleton. J Cell Sci 2000, 113:571-585.
    • (2000) J Cell Sci , vol.113 , pp. 571-585
    • Pruyne, D.1    Bretscher, A.2
  • 16
    • 0034923514 scopus 로고    scopus 로고
    • Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
    • 10.1146/annurev.biochem.70.1.703, 11395421
    • Dohlman HG, Thorner JW. Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles. Annu Rev Biochem 2001, 70:703-754. 10.1146/annurev.biochem.70.1.703, 11395421.
    • (2001) Annu Rev Biochem , vol.70 , pp. 703-754
    • Dohlman, H.G.1    Thorner, J.W.2
  • 17
    • 57349128869 scopus 로고    scopus 로고
    • Accuracy of direct gradient sensing by single cells
    • 10.1073/pnas.0804688105, 2572938, 18843108
    • Endres RG, Wingreen NS. Accuracy of direct gradient sensing by single cells. Proc Natl Acad Sci USA 2008, 105:15749-15754. 10.1073/pnas.0804688105, 2572938, 18843108.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15749-15754
    • Endres, R.G.1    Wingreen, N.S.2
  • 18
    • 58049221114 scopus 로고    scopus 로고
    • Receptor noise limitations on cheotactic sensing
    • 10.1073/pnas.0804702105, 2614751, 19064934
    • Rappel W-J, Levine H. Receptor noise limitations on cheotactic sensing. Proc Natl Acad Sci USA 2008, 105:19270-19275. 10.1073/pnas.0804702105, 2614751, 19064934.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19270-19275
    • Rappel, W.-.J.1    Levine, H.2
  • 20
    • 34548378653 scopus 로고    scopus 로고
    • An information-theoretic characterization of the optimal gradient sensing response of cells
    • 10.1371/journal.pcbi.0030153, 1937015, 17676949
    • Andrews BW, Iglesias PA. An information-theoretic characterization of the optimal gradient sensing response of cells. PLoS Comput Biol 2007, 3:e153. 10.1371/journal.pcbi.0030153, 1937015, 17676949.
    • (2007) PLoS Comput Biol , vol.3
    • Andrews, B.W.1    Iglesias, P.A.2
  • 22
    • 56349125826 scopus 로고    scopus 로고
    • Symmetry-breaking polarization driven by a Cdc42p GEF-PAK complex
    • 10.1016/j.cub.2008.09.060, 2803100, 19013066
    • Kozubowski L, Saito K, Johnson JM, Howell AS, Zyla TR, Lew DJ. Symmetry-breaking polarization driven by a Cdc42p GEF-PAK complex. Curr Biol 2008, 18:1719-1726. 10.1016/j.cub.2008.09.060, 2803100, 19013066.
    • (2008) Curr Biol , vol.18 , pp. 1719-1726
    • Kozubowski, L.1    Saito, K.2    Johnson, J.M.3    Howell, A.S.4    Zyla, T.R.5    Lew, D.J.6
  • 23
    • 27144517984 scopus 로고    scopus 로고
    • Interlinked fast and slow positive feedback loops drive reliable cell decisions
    • 10.1126/science.1113834, 3175767, 16239477
    • Brandman O, JE F, Li R, Meyer T. Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science 2005, 310:496-498. 10.1126/science.1113834, 3175767, 16239477.
    • (2005) Science , vol.310 , pp. 496-498
    • Brandman, O.1    JE, F.2    Li, R.3    Meyer, T.4
  • 24
    • 0037458909 scopus 로고    scopus 로고
    • Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase
    • 10.1126/science.1080944, 12560471
    • Wedlich-Soldner R, Altschuler S, Wu L, Li R. Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science 2003, 299:1231-1235. 10.1126/science.1080944, 12560471.
    • (2003) Science , vol.299 , pp. 1231-1235
    • Wedlich-Soldner, R.1    Altschuler, S.2    Wu, L.3    Li, R.4
  • 25
    • 34147175165 scopus 로고    scopus 로고
    • Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity
    • 10.1016/j.cell.2007.02.043, 2000346, 17448998
    • Marco E, Wedlich-Soldner R, Li R, Altschuler SJ, Wu LF. Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity. Cell 2007, 129:411-422. 10.1016/j.cell.2007.02.043, 2000346, 17448998.
    • (2007) Cell , vol.129 , pp. 411-422
    • Marco, E.1    Wedlich-Soldner, R.2    Li, R.3    Altschuler, S.J.4    Wu, L.F.5
  • 26
    • 0031977016 scopus 로고    scopus 로고
    • The riddle of MAP kinase signaling specificity
    • 10.1016/S0168-9525(98)01425-5, 9594663
    • Madhani HD, Fink GR. The riddle of MAP kinase signaling specificity. Trends Genet 1998, 14:151-155. 10.1016/S0168-9525(98)01425-5, 9594663.
    • (1998) Trends Genet , vol.14 , pp. 151-155
    • Madhani, H.D.1    Fink, G.R.2
  • 27
    • 4544300880 scopus 로고    scopus 로고
    • A walk-through of the yeast mating pheromone response pathway
    • 10.1016/j.peptides.2003.10.022, 3017507, 15374648
    • Bardwell L. A walk-through of the yeast mating pheromone response pathway. Peptides 2004, 25:1465-1476. 10.1016/j.peptides.2003.10.022, 3017507, 15374648.
    • (2004) Peptides , vol.25 , pp. 1465-1476
    • Bardwell, L.1
  • 28
    • 0037195112 scopus 로고    scopus 로고
    • Cell surface polarization during yeast mating
    • 10.1073/pnas.172517799, 137858, 12374868
    • Bagnat M, Simons K. Cell surface polarization during yeast mating. Proc Natl Acad Sci USA 2002, 99:14183-14188. 10.1073/pnas.172517799, 137858, 12374868.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14183-14188
    • Bagnat, M.1    Simons, K.2
  • 29
    • 0036219106 scopus 로고    scopus 로고
    • Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils
    • 10.1016/S0006-3495(02)75373-3, 1302448, 11751295
    • Levchenko A, Iglesias PA. Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils. Biophys J 2002, 82:50-63. 10.1016/S0006-3495(02)75373-3, 1302448, 11751295.
    • (2002) Biophys J , vol.82 , pp. 50-63
    • Levchenko, A.1    Iglesias, P.A.2
  • 30
    • 0034712843 scopus 로고    scopus 로고
    • Robust perfect adaptation in bacterial chemotaxis through integral feedback control
    • 10.1073/pnas.97.9.4649, 18287, 10781070
    • Yi T-M, Huang Y, Simon MI, Doyle J. Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc Natl Acad Sci USA 2000, 97:4649-4653. 10.1073/pnas.97.9.4649, 18287, 10781070.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4649-4653
    • Yi, T.-.M.1    Huang, Y.2    Simon, M.I.3    Doyle, J.4
  • 32
    • 0027218647 scopus 로고
    • Polarization of yeast cells in spatial gradients of alpha mating factor
    • 10.1073/pnas.90.18.8332, 47350, 8397402
    • Segall JE. Polarization of yeast cells in spatial gradients of alpha mating factor. Proc Natl Acad Sci USA 1993, 90:8332-8336. 10.1073/pnas.90.18.8332, 47350, 8397402.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8332-8336
    • Segall, J.E.1
  • 34
    • 38949194331 scopus 로고    scopus 로고
    • Noise propagation and signaling sensitivity in biological networks: A role for positive feedback
    • 10.1371/journal.pcbi.0040008, 2174979, 18179281
    • Hornung G, Barkai N. Noise propagation and signaling sensitivity in biological networks: A role for positive feedback. PLoS Comput Biol 2008, 4:e8. 10.1371/journal.pcbi.0040008, 2174979, 18179281.
    • (2008) PLoS Comput Biol , vol.4
    • Hornung, G.1    Barkai, N.2
  • 35
    • 54249137797 scopus 로고    scopus 로고
    • Feedback loops shape cellular signals in space and time
    • 10.1126/science.1160617, 2680159, 18927383
    • Brandman O, Meyer T. Feedback loops shape cellular signals in space and time. Science 2008, 322:390-395. 10.1126/science.1160617, 2680159, 18927383.
    • (2008) Science , vol.322 , pp. 390-395
    • Brandman, O.1    Meyer, T.2
  • 36
    • 0037605637 scopus 로고    scopus 로고
    • Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
    • 10.1063/1.1349894, 12779456
    • Ferrell JE, Xiong W. Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible. Chaos 2001, 11:227-236. 10.1063/1.1349894, 12779456.
    • (2001) Chaos , vol.11 , pp. 227-236
    • Ferrell, J.E.1    Xiong, W.2
  • 37
    • 40749085952 scopus 로고    scopus 로고
    • Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses
    • Ferrell JE. Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses. Curr Biol 2008, 18:244-245.
    • (2008) Curr Biol , vol.18 , pp. 244-245
    • Ferrell, J.E.1
  • 38
    • 39149118309 scopus 로고    scopus 로고
    • Navigating through models of chemotaxis
    • 10.1016/j.ceb.2007.11.011, 18207721
    • Iglesias PA, Devreotes PN. Navigating through models of chemotaxis. Curr Opin Cell Biol 2008, 20:35-40. 10.1016/j.ceb.2007.11.011, 18207721.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 35-40
    • Iglesias, P.A.1    Devreotes, P.N.2
  • 39
    • 0842285841 scopus 로고    scopus 로고
    • Summing up the noise in gene networks
    • 10.1038/nature02257, 14749823
    • Paulsson J. Summing up the noise in gene networks. Nature 2004, 427:415-418. 10.1038/nature02257, 14749823.
    • (2004) Nature , vol.427 , pp. 415-418
    • Paulsson, J.1
  • 44
    • 0141703270 scopus 로고    scopus 로고
    • A quantitative characterization of the yeast heterotrimeric G protein cycle
    • 10.1073/pnas.1834247100, 196877, 12960402
    • Yi TM, Kitano H, Simon MI. A quantitative characterization of the yeast heterotrimeric G protein cycle. Proc Natl Acad Sci USA 2003, 100:10764-10769. 10.1073/pnas.1834247100, 196877, 12960402.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10764-10769
    • Yi, T.M.1    Kitano, H.2    Simon, M.I.3
  • 45
    • 71549171886 scopus 로고    scopus 로고
    • Accuracy of direct gradient sensing by cell-surface receptors
    • Endres RG, Wingreen NS. Accuracy of direct gradient sensing by cell-surface receptors. Prog Biophys Mol Bio 2009, 100:33-39.
    • (2009) Prog Biophys Mol Bio , vol.100 , pp. 33-39
    • Endres, R.G.1    Wingreen, N.S.2
  • 46
    • 0037371660 scopus 로고    scopus 로고
    • Identification of p21-activated kinase specificity determinants in budding yeast: a single amino acid substitution imparts Ste20 specificity to Cla4
    • 10.1128/MCB.23.5.1569-1580.2003, 151699, 12588977
    • Keniry ME, Sprague GF. Identification of p21-activated kinase specificity determinants in budding yeast: a single amino acid substitution imparts Ste20 specificity to Cla4. Mol Cell Biol 2003, 23:1569-1580. 10.1128/MCB.23.5.1569-1580.2003, 151699, 12588977.
    • (2003) Mol Cell Biol , vol.23 , pp. 1569-1580
    • Keniry, M.E.1    Sprague, G.F.2
  • 47
    • 0037007225 scopus 로고    scopus 로고
    • A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization
    • 10.1093/emboj/21.7.1565, 125953, 11927541
    • Butty AC, Perrinjaquet N, Petit A, Jaquenoud M, Segall JE, Hofmann K, Zwahlen C, Peter M. A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization. Embo J 2002, 21:1565-1576. 10.1093/emboj/21.7.1565, 125953, 11927541.
    • (2002) Embo J , vol.21 , pp. 1565-1576
    • Butty, A.C.1    Perrinjaquet, N.2    Petit, A.3    Jaquenoud, M.4    Segall, J.E.5    Hofmann, K.6    Zwahlen, C.7    Peter, M.8
  • 48
    • 0030932405 scopus 로고    scopus 로고
    • Bni1p, a yeast Formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis
    • 10.1126/science.276.5309.118, 9082982
    • Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, Peter M, Boone C. Bni1p, a yeast Formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 1997, 276:118-122. 10.1126/science.276.5309.118, 9082982.
    • (1997) Science , vol.276 , pp. 118-122
    • Evangelista, M.1    Blundell, K.2    Longtine, M.S.3    Chow, C.J.4    Adames, N.5    Pringle, J.R.6    Peter, M.7    Boone, C.8
  • 49
    • 33646764616 scopus 로고    scopus 로고
    • Spontaneous polarization in eukaryotic gradient sensing: A mathematical model based on mutual inhibition of frontness and backness pathways
    • 10.1016/j.jtbi.2005.10.022, 16343548
    • Narang A. Spontaneous polarization in eukaryotic gradient sensing: A mathematical model based on mutual inhibition of frontness and backness pathways. J Theor Biol 2006, 240:538-553. 10.1016/j.jtbi.2005.10.022, 16343548.
    • (2006) J Theor Biol , vol.240 , pp. 538-553
    • Narang, A.1
  • 50
    • 33847394655 scopus 로고    scopus 로고
    • MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast
    • 10.1038/nature05561, 17310144
    • Paliwal S, Iglesias PA, Campbell K, Hilioti Z, Groisman A, Levchenko A. MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast. Nature 2007, 446:46-51. 10.1038/nature05561, 17310144.
    • (2007) Nature , vol.446 , pp. 46-51
    • Paliwal, S.1    Iglesias, P.A.2    Campbell, K.3    Hilioti, Z.4    Groisman, A.5    Levchenko, A.6
  • 51
    • 57749106716 scopus 로고    scopus 로고
    • Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50
    • 10.1074/jbc.C800179200, 2662209, 18854322
    • Hao N, Zeng Y, Elston TC, Dohlman HG. Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50. J Biol Chem 2008, 283:33798-33802. 10.1074/jbc.C800179200, 2662209, 18854322.
    • (2008) J Biol Chem , vol.283 , pp. 33798-33802
    • Hao, N.1    Zeng, Y.2    Elston, T.C.3    Dohlman, H.G.4
  • 52
    • 57349179035 scopus 로고    scopus 로고
    • Robust spatial sensing of mating pheromone gradients by yeast cells
    • 10.1371/journal.pone.0003865, 2586657, 19052645
    • Moore TI, Chou C-S, Nie Q, Jeon NL, Yi T-M. Robust spatial sensing of mating pheromone gradients by yeast cells. PLoS ONE 2008, 3:e3865. 10.1371/journal.pone.0003865, 2586657, 19052645.
    • (2008) PLoS ONE , vol.3
    • Moore, T.I.1    Chou, C.-.S.2    Nie, Q.3    Jeon, N.L.4    Yi, T.-.M.5
  • 53
    • 57349179035 scopus 로고    scopus 로고
    • Robust spatial sensing of mating pheromone gradients by yeast cells
    • 10.1371/journal.pone.0003865, 2586657, 19052645
    • Moore TI, Chou CS, Nie Q, Jeon NL, Yi TM. Robust spatial sensing of mating pheromone gradients by yeast cells. PLoS One 2008, 3:e3865. 10.1371/journal.pone.0003865, 2586657, 19052645.
    • (2008) PLoS One , vol.3
    • Moore, T.I.1    Chou, C.S.2    Nie, Q.3    Jeon, N.L.4    Yi, T.M.5
  • 54
    • 77952093377 scopus 로고    scopus 로고
    • The scaffold protein Ste5 directly controls a switch-like mating decision in yeast
    • 10.1038/nature08946, 20400943
    • Malleshaiah MK, Shahrezaei V, Swain PS, Michnick SW. The scaffold protein Ste5 directly controls a switch-like mating decision in yeast. Nature 2010, 465:101-105. 10.1038/nature08946, 20400943.
    • (2010) Nature , vol.465 , pp. 101-105
    • Malleshaiah, M.K.1    Shahrezaei, V.2    Swain, P.S.3    Michnick, S.W.4
  • 55
    • 49649109812 scopus 로고    scopus 로고
    • Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade
    • 10.1016/j.cub.2008.07.050, 2562168, 18722124
    • Takahashi S, Pryciak PM. Membrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade. Curr Biol 2008, 18:1184-1191. 10.1016/j.cub.2008.07.050, 2562168, 18722124.
    • (2008) Curr Biol , vol.18 , pp. 1184-1191
    • Takahashi, S.1    Pryciak, P.M.2
  • 56
    • 77951639384 scopus 로고    scopus 로고
    • A combination of multisite phosphorylation and substrate sequestration produces switchlike responses
    • 10.1016/j.bpj.2009.12.4307, 2856190, 20409458
    • Liu X, Bardwell L, Nie Q. A combination of multisite phosphorylation and substrate sequestration produces switchlike responses. Biophys J 2010, 98:1396-1407. 10.1016/j.bpj.2009.12.4307, 2856190, 20409458.
    • (2010) Biophys J , vol.98 , pp. 1396-1407
    • Liu, X.1    Bardwell, L.2    Nie, Q.3


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