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Volumn 23, Issue 5, 2003, Pages 1569-1580

Identification of p21-activated kinase specificity determinants in budding yeast: A single amino acid substitution imparts Ste20 specificity to Cla4

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; GUANOSINE TRIPHOSPHATASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHEROMONE; PLECKSTRIN; PROTEIN; PROTEIN CDC42; PROTEIN CLA4; PROTEIN KINASE; PROTEIN P21; PROTEIN P21 ACTIVATED KINASE; PROTEIN STE20; RHO KINASE; THREONINE; UNCLASSIFIED DRUG;

EID: 0037371660     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.5.1569-1580.2003     Document Type: Article
Times cited : (13)

References (48)
  • 2
    • 0030848931 scopus 로고    scopus 로고
    • Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis
    • Benton, B. K., A. Tinkelenberg, I. Gonzalez, and F. R. Cross. 1997. Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis. Mol. Cell. Biol. 17:5067-5076.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5067-5076
    • Benton, B.K.1    Tinkelenberg, A.2    Gonzalez, I.3    Cross, F.R.4
  • 4
    • 0035831555 scopus 로고    scopus 로고
    • Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p
    • Bose, I., J. E. Irazoqui, J. J. Moskow, E. S. Bardes, T. R. Zyla, and D. J. Lew. 2001. Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p. J. Biol. Chem. 276:7176-7186.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7176-7186
    • Bose, I.1    Irazoqui, J.E.2    Moskow, J.J.3    Bardes, E.S.4    Zyla, T.R.5    Lew, D.J.6
  • 5
    • 0030134625 scopus 로고    scopus 로고
    • Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway
    • Brown, J. L., L. Stowers, M. Baer, J. Trejo, S. Coughlin, and J. Chant. 1996. Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway. Curr. Biol. 6:598-605.
    • (1996) Curr. Biol. , vol.6 , pp. 598-605
    • Brown, J.L.1    Stowers, L.2    Baer, M.3    Trejo, J.4    Coughlin, S.5    Chant, J.6
  • 6
    • 0028931727 scopus 로고
    • Patterns of bud-site selection in the yeast Saccharomyces cerevisiae
    • Chant, J., and J. R. Pringle. 1995. Patterns of bud-site selection in the yeast Saccharomyces cerevisiae. J. Cell Biol. 129:751-765.
    • (1995) J. Cell Biol. , vol.129 , pp. 751-765
    • Chant, J.1    Pringle, J.R.2
  • 7
    • 0030688862 scopus 로고    scopus 로고
    • Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway
    • Cook, J. G., L. Bardwell, and J. Thorner. 1997. Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 390:85-88.
    • (1997) Nature , vol.390 , pp. 85-88
    • Cook, J.G.1    Bardwell, L.2    Thorner, J.3
  • 8
    • 0034610273 scopus 로고    scopus 로고
    • Glucose depletion causes haploid invasive growth in yeast
    • Cullen, P. J., and G. F. Sprague, Jr. 2000. Glucose depletion causes haploid invasive growth in yeast. Proc. Natl. Acad. Sci. USA 97:13619-13624.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13619-13624
    • Cullen, P.J.1    Sprague G.F., Jr.2
  • 9
    • 0029091498 scopus 로고
    • Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast
    • Cvrckova, F., C. De Virgillo, E. Manser, J. R. Pringle, and K. Nasmyth. 1995. Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes Dev. 9:1817-1830.
    • (1995) Genes Dev. , vol.9 , pp. 1817-1830
    • Cvrckova, F.1    De Virgillo, C.2    Manser, E.3    Pringle, J.R.4    Nasmyth, K.5
  • 10
    • 0033635230 scopus 로고    scopus 로고
    • Phosphorylation of the cdc42 exchange factor cdc24 by the PAK-like kinase cla4 may regulate polarized growth in yeast
    • Gulli, M., M. Jaquenoud, Y. Shimada, G. Niederhauser, P. Wiget, and M. Peter. 2000. Phosphorylation of the cdc42 exchange factor cdc24 by the PAK-like kinase cla4 may regulate polarized growth in yeast. Mol. Cell 6:1155-1167.
    • (2000) Mol. Cell. , vol.6 , pp. 1155-1167
    • Gulli, M.1    Jaquenoud, M.2    Shimada, Y.3    Niederhauser, G.4    Wiget, P.5    Peter, M.6
  • 11
    • 0033571294 scopus 로고    scopus 로고
    • PAK-family kinases regulate cell and actin polarization throughout the cell cycle of Saccharomyces cerevisiae
    • Holly, S. P., and K. J. Blumer. 1999. PAK-family kinases regulate cell and actin polarization throughout the cell cycle of Saccharomyces cerevisiae. J. Cell Biol. 147:845-856.
    • (1999) J. Cell Biol. , vol.147 , pp. 845-856
    • Holly, S.P.1    Blumer, K.J.2
  • 12
    • 0023674389 scopus 로고
    • Identification of a DNA segment that is necessary and sufficient for α-specific gene control in Saccharomyces cerevisiae: Implications for regulation of α-specific and a-specific genes
    • Jarvis, E. E., D. C. Hagen, and G. F. Sprague, Jr. 1988. Identification of a DNA segment that is necessary and sufficient for α-specific gene control in Saccharomyces cerevisiae: implications for regulation of α-specific and a-specific genes. Mol. Cell. Biol. 8:309-320.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 309-320
    • Jarvis, E.E.1    Hagen, D.C.2    Sprague G.F., Jr.3
  • 13
    • 0028609209 scopus 로고
    • JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation
    • Kallunki, T., B. Su, I. Tsigelny, H. K. Sluss, B. Derijard, G. Moore, R. Davis, and M. Karin. 1994. JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev. 8:2996-3007.
    • (1994) Genes Dev. , vol.8 , pp. 2996-3007
    • Kallunki, T.1    Su, B.2    Tsigelny, I.3    Sluss, H.K.4    Derijard, B.5    Moore, G.6    Davis, R.7    Karin, M.8
  • 14
    • 0033522510 scopus 로고    scopus 로고
    • Src family kinases are required for integrin but not PDGFR signal transduction
    • Klinghoffer, R. A., C. Sachsenmaier, J. A. Cooper, and P. Soriano. 1999. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J. 18:2459-2471.
    • (1999) EMBO J. , vol.18 , pp. 2459-2471
    • Klinghoffer, R.A.1    Sachsenmaier, C.2    Cooper, J.A.3    Soriano, P.4
  • 15
    • 0031015562 scopus 로고    scopus 로고
    • Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase
    • Leberer, E., W. Cunle, T. Leeuw, A. Fourest-Lieuvin, J. Segall, and D. Thomas. 1997. Functional characterization of the Cdc42p binding domain of yeast Ste20p protein kinase. EMBO J. 16:83-97.
    • (1997) EMBO J. , vol.16 , pp. 83-97
    • Leberer, E.1    Cunle, W.2    Leeuw, T.3    Fourest-Lieuvin, A.4    Segall, J.5    Thomas, D.6
  • 16
    • 0027495599 scopus 로고
    • Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: Structural and functional similarity of Ste5 to Farl
    • Leberer, E., D. Dignard, D. Harcus, L. Hougan, M. Whiteway, and D. Y. Thomas. 1993. Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Farl. Mol. Gen. Genet. 241:241-254.
    • (1993) Mol. Gen. Genet. , vol.241 , pp. 241-254
    • Leberer, E.1    Dignard, D.2    Harcus, D.3    Hougan, L.4    Whiteway, M.5    Thomas, D.Y.6
  • 17
    • 0027048684 scopus 로고
    • The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components
    • Leberer, E., D. Dignard, D. Harcus, D. Y. Thomas, and M. Whiteway. 1992. The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components. EMBO J. 11:4815-4824.
    • (1992) EMBO J. , vol.11 , pp. 4815-4824
    • Leberer, E.1    Dignard, D.2    Harcus, D.3    Thomas, D.Y.4    Whiteway, M.5
  • 18
    • 0032495478 scopus 로고    scopus 로고
    • Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases
    • Leeuw, T., C. Wu, J. D. Schrag, M. Whiteway, D. Y. Thomas, and E. Leberer. 1998. Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature 391:191-195.
    • (1998) Nature , vol.391 , pp. 191-195
    • Leeuw, T.1    Wu, C.2    Schrag, J.D.3    Whiteway, M.4    Thomas, D.Y.5    Leberer, E.6
  • 19
    • 0034604338 scopus 로고    scopus 로고
    • Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch
    • Lei, M., W. Lu, W. Meng, M. C. Parrini, M. J. Eck, B. J. Mayer, and S. C. Harrison. 2000. Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch. Cell 102:387-397.
    • (2000) Cell , vol.102 , pp. 387-397
    • Lei, M.1    Lu, W.2    Meng, W.3    Parrini, M.C.4    Eck, M.J.5    Mayer, B.J.6    Harrison, S.C.7
  • 20
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • Longtine, M. S., A. McKenzie, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
    • (1998) Yeast , vol.14 , pp. 953-961
    • Longtine, M.S.1    McKenzie, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 22
    • 0030731714 scopus 로고    scopus 로고
    • MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation
    • Madhani, H. D., C. A. Styles, and G. R. Fink. 1997. MAP kinases with distinct inhibitory functions impart signaling specificity during yeast differentiation. Cell 91:673-684.
    • (1997) Cell , vol.91 , pp. 673-684
    • Madhani, H.D.1    Styles, C.A.2    Fink, G.R.3
  • 23
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by Cdc42 and Rac1
    • Manser, E., T. Leung, H. Salihuddin, Z. S. Zhao, and L. Lim. 1994. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367:40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.S.4    Lim, L.5
  • 24
    • 0031016037 scopus 로고    scopus 로고
    • Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase
    • Martin, H., A. Mendoza, J. M. Rodriguez-Pachon, M. Molina, and C. Nombela. 1997. Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase. Mol. Microbiol. 23:431-444.
    • (1997) Mol. Microbiol. , vol.23 , pp. 431-444
    • Martin, H.1    Mendoza, A.2    Rodriguez-Pachon, J.M.3    Molina, M.4    Nombela, C.5
  • 26
    • 0029895340 scopus 로고    scopus 로고
    • Ras2 signals via the Cdc421Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae
    • Mosch, H. U., R. L. Roberts, and G. R. Fink. 1996. Ras2 signals via the Cdc421Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 93:5352-5356.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5352-5356
    • Mosch, H.U.1    Roberts, R.L.2    Fink, G.R.3
  • 27
    • 0033801741 scopus 로고    scopus 로고
    • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae
    • Moskow, J. J., A. S. Gladfelter, R. E. Lamson, P. M. Pryciak, and D. J. Lew. 2000. Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. Mol. Cell. Biol. 20:7559-7571
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7559-7571
    • Moskow, J.J.1    Gladfelter, A.S.2    Lamson, R.E.3    Pryciak, P.M.4    Lew, D.J.5
  • 28
    • 0032530170 scopus 로고    scopus 로고
    • The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae
    • O'Rourke, S. M., and I. Herskowitz. 1998. The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae. Genes Dev. 12:2874-2886.
    • (1998) Genes Dev. , vol.12 , pp. 2874-2886
    • O'Rourke, S.M.1    Herskowitz, I.2
  • 29
    • 0031658234 scopus 로고    scopus 로고
    • Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
    • Posas, F., E. A. Witten, and H. Saito. 1998. Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway. Mol. Cell. Biol. 18:5788-5796.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5788-5796
    • Posas, F.1    Witten, E.A.2    Saito, H.3
  • 30
    • 0028046412 scopus 로고
    • Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
    • Printen, J. A., and G. F. Sprague, Jr. 1994. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138:609-619.
    • (1994) Genetics , vol.138 , pp. 609-619
    • Printen, J.A.1    Sprague G.F., Jr.2
  • 31
    • 0034282495 scopus 로고    scopus 로고
    • Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway
    • Raitt, D. C., F. Posas, and H. Saito. 2000. Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway. EMBO J. 19:4623-4631.
    • (2000) EMBO J. , vol.19 , pp. 4623-4631
    • Raitt, D.C.1    Posas, F.2    Saito, H.3
  • 32
    • 0027530380 scopus 로고
    • A dominant truncation allele identifies a gene, STE20, that encodes a putative protein kinase necessary for mating in Saccharomyces cerevisiae
    • Ramer, S. W., and R. W. Davis. 1993. A dominant truncation allele identifies a gene, STE20, that encodes a putative protein kinase necessary for mating in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 90:452-456.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 452-456
    • Ramer, S.W.1    Davis, R.W.2
  • 33
    • 0033546275 scopus 로고    scopus 로고
    • 2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast
    • 2/M morphogenetic checkpoint regulating the apical-isotropic switch and nuclear division in yeast. J. Biol. Chem. 274:16861-16870.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16861-16870
    • Richman, T.J.1    Sawyer, M.M.2    Johnson, D.I.3
  • 34
    • 0028670651 scopus 로고
    • Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: Mating and invasive growth
    • Roberts, R. L., and G. R. Fink. 1994. Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev. 8:2974-2985.
    • (1994) Genes Dev. , vol.8 , pp. 2974-2985
    • Roberts, R.L.1    Fink, G.R.2
  • 36
    • 0029157033 scopus 로고
    • Structure-function relationships of the yeast cyclin -dependent kinase Pho85
    • Santos, R. C., N. C. Waters, C. L. Creasy, and L. W. Bergman. 1995. Structure-function relationships of the yeast cyclin -dependent kinase Pho85. Mol. Cell. Biol. 15:5482-5491.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5482-5491
    • Santos, R.C.1    Waters, N.C.2    Creasy, C.L.3    Bergman, L.W.4
  • 38
    • 0033919372 scopus 로고    scopus 로고
    • Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae
    • Sheu, Y. J., Y. Barral, and M. Snyder. 2000. Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae. Mol. Cell. Biol. 20:5235-5247.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5235-5247
    • Sheu, Y.J.1    Barral, Y.2    Snyder, M.3
  • 39
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 40
    • 0023806075 scopus 로고
    • Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
    • Smith, D. B., and K. S. Johnson, 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
    • (1988) Gene , vol.67 , pp. 31-40
    • Smith, D.B.1    Johnson, K.S.2
  • 41
    • 0025971103 scopus 로고
    • Assay of yeast mating reaction
    • Sprague, G. F. 1991. Assay of yeast mating reaction. Methods Enzymol. 94:77-93.
    • (1991) Methods Enzymol. , vol.94 , pp. 77-93
    • Sprague, G.F.1
  • 42
    • 0033501047 scopus 로고    scopus 로고
    • The elm1 kinase functions in a mitotic signaling network in budding yeast
    • Sreenivasan, A., and D. Kellogg. 1999. The elm1 kinase functions in a mitotic signaling network in budding yeast. Mol. Cell. Biol. 19:7983-7994.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7983-7994
    • Sreenivasan, A.1    Kellogg, D.2
  • 43
    • 0028964465 scopus 로고
    • Cytokine signaling through nonreceptor protein tyrosine kinases
    • Taniguchi, T. 1995. Cytokine signaling through nonreceptor protein tyrosine kinases. Science 268:251-255.
    • (1995) Science , vol.268 , pp. 251-255
    • Taniguchi, T.1
  • 44
    • 0032504990 scopus 로고    scopus 로고
    • Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family
    • Tjandra, H., J. Compton, and D. Kellogg. 1998. Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family. Curr. Biol. 8:991-1000.
    • (1998) Curr. Biol. , vol.8 , pp. 991-1000
    • Tjandra, H.1    Compton, J.2    Kellogg, D.3
  • 45
    • 0032907949 scopus 로고    scopus 로고
    • Genetic evidence for Pak1 autoinhibition and its release by Cdc42
    • Tu, H., and M. Wigler. 1999. Genetic evidence for Pak1 autoinhibition and its release by Cdc42. Mol. Cell. Biol. 19:602-611.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 602-611
    • Tu, H.1    Wigler, M.2
  • 46
    • 0032528534 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
    • Ushiro, H., T. Tsutsumi, K. Suzuki, T. Kayahara, and K. Nakano. 1998. Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia. Arch. Biochem. Biophys. 355:233-240.
    • (1998) Arch. Biochem. Biophys. , vol.355 , pp. 233-240
    • Ushiro, H.1    Tsutsumi, T.2    Suzuki, K.3    Kayahara, T.4    Nakano, K.5
  • 47
    • 0029066439 scopus 로고
    • Molecular characterization of Ste20, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae
    • Wu, C., M. Whiteway, D. Thomas, and E. Lebere. 1995. Molecular characterization of Ste20, a potential mitogen-activated protein or extracellular signal-regulated kinase kinase (MEK) kinase kinase from Saccharomyces cerevisiae. J. Biol. Chem. 270:15984-15992.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15984-15992
    • Wu, C.1    Whiteway, M.2    Thomas, D.3    Lebere, E.4
  • 48
    • 0027499591 scopus 로고
    • Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases
    • Zhou, Z., A. Gartner, R. Cade, G. Ammerer, and B. Errede. 1993. Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases. Mol. Cell. Biol. 13:2069-2080.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 2069-2080
    • Zhou, Z.1    Gartner, A.2    Cade, R.3    Ammerer, G.4    Errede, B.5


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