Mutational Analysis of the Conserved Cysteines of the Rat P2X2 Purinoceptor

Journal of Neuroscience

Volumn 22, Issue 10, 2002, Pages 3873-3880

  Clyne, J Dylan ^a   Wang, Lin Fang ^a   Hume, Richard I ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Cell Devmtl Biol Grp Dept B   (United States)

Author keywords

Disulfide bonds; DTT; Mutagenesis; P2X; PH; Purinergic; Zinc

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALANINE; AMMONIUM DERIVATIVE; CYSTEINE DERIVATIVE; METHYL GROUP; MUTANT PROTEIN; PURINE P2X RECEPTOR; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ZINC; [2 (TRIMETHYLAMMONIUM)ETHYL]METHANETHIOSULFONATE BROMIDE; (2 (TRIMETHYLAMMONIUM)ETHYL)METHANETHIOSULFONATE; (2-(TRIMETHYLAMMONIUM)ETHYL)METHANETHIOSULFONATE; CYSTEINE; DITHIOTHREITOL; MESYLIC ACID DERIVATIVE; PURINE P2 RECEPTOR; PURINE P2X2 RECEPTOR; REDUCING AGENT; THIOL REAGENT;

ACIDITY; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISULFIDE BOND; EMBRYO; HUMAN; HUMAN CELL; ION CURRENT; KIDNEY CELL; METAL BINDING; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPECIES COMPARISON; WILD TYPE; XENOPUS; ANIMAL; CELL LINE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; GENETICS; KIDNEY; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; CONSERVED SEQUENCE; CYSTEINE; DITHIOTHREITOL; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KIDNEY; MEMBRANE POTENTIALS; MESYLATES; MUTAGENESIS, SITE-DIRECTED; OOCYTES; RATS; RECEPTORS, PURINERGIC P2; REDUCING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL REAGENTS; XENOPUS; ZINC;

EID: 0037095757     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-10-03873.2002     Document Type: Article

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