-
1
-
-
0032578279
-
Primary pulmonary hypertension
-
Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet. 1998;352: 719-725. (Pubitemid 28398718)
-
(1998)
Lancet
, vol.352
, Issue.9129
, pp. 719-725
-
-
Gaine, S.P.1
Rubin, L.J.2
-
2
-
-
67649632034
-
Diagnosis and assessment of pulmonary hypertension
-
Badesch DB, Champion HC, Sanchez MA, Hoeper MM, Loyd JE, Manes A, McGoon M, Naeije R, Olshewski H, Oudiz RJ, Torbicki A. Diagnosis and assessment of pulmonary hypertension. J Am Coll Cardiol. 2009;54: S55-S66.
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Badesch, D.B.1
Champion, H.C.2
Sanchez, M.A.3
Hoeper, M.M.4
Loyd, J.E.5
Manes, A.6
McGoon, M.7
Naeije, R.8
Olshewski, H.9
Oudiz, R.J.10
Torbicki, A.11
-
3
-
-
0025837793
-
Survival in patients with primary pulmonary hypertension: Results from a national prospective registry
-
D'Alonzo GE, Barst RJ, Ayres SM, Bergofsky EH, Brundage BH, Detre KM, Fishman AP, Goldring RM, Groves BM, Kernis JT, Levy PS, Pietra GS, Reid LM, Reeves JT, Stuart R, Vreim CE, Williams GW, Wu M. Survival in patients with primary pulmonary hypertension: results from a national prospective registry. Ann Intern Med. 1991;115:343-349.
-
(1991)
Ann Intern Med
, vol.115
, pp. 343-349
-
-
D'Alonzo, G.E.1
Barst, R.J.2
Ayres, S.M.3
Bergofsky, E.H.4
Brundage, B.H.5
Detre, K.M.6
Fishman, A.P.7
Goldring, R.M.8
Groves, B.M.9
Kernis, J.T.10
Levy, P.S.11
Pietra, G.S.12
Reid, L.M.13
Reeves, J.T.14
Stuart, R.15
Vreim, C.E.16
Williams, G.W.17
Wu, M.18
-
4
-
-
0037126044
-
Survival in primary pulmonary hypertension: The impact of epoprostenol therapy
-
McLaughlin VV, Shillington A, Rich S. Survival in primary pulmonary hypertension: the impact of epoprostenol therapy. Circulation. 2002;106: 1477-1482.
-
(2002)
Circulation
, vol.106
, pp. 1477-1482
-
-
McLaughlin, V.V.1
Shillington, A.2
Rich, S.3
-
5
-
-
33746827371
-
Survival in patients with pulmonary arterial hypertension treated with first-line bosentan
-
DOI 10.1111/j.1365-2362.2006.01688.x
-
McLaughlin VV. Survival in patients with pulmonary arterial hypertension treated with first-line bosentan. Eur J Clin Invest. 2006;36(Suppl 3):10-15. (Pubitemid 44179776)
-
(2006)
European Journal of Clinical Investigation
, vol.36
, Issue.SUPPL. 3
, pp. 10-15
-
-
McLaughlin, V.V.1
-
6
-
-
4143118866
-
Cellular and molecular mechanisms of pulmonary vascular remodeling: Role in the development of pulmonary hypertension
-
DOI 10.1016/j.mvr.2004.06.001, PII S0026286204000731
-
Mandegar M, Fung YC, Huang W, Remillard CV, Rubin LJ, Yuan JX. Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension. Microvasc Res. 2004;68:75-103. (Pubitemid 39093882)
-
(2004)
Microvascular Research
, vol.68
, Issue.2
, pp. 75-103
-
-
Mandegar, M.1
Fung, Y.-C.B.2
Huang, W.3
Remillard, C.V.4
Rubin, L.J.5
Yuan, J.X.-J.6
-
7
-
-
67649579669
-
Updated clinical classification of pulmonary hypertension
-
Simonneau G, Robbins IM, Beghetti M, Channick RN, Delcroix M, Denton CP, Elliott CG, Gaine SP, Gladwin MT, Jing ZC, Krowka MJ, Langleben D, Nakahashi N, Souza R. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009;54:S43-S54.
-
(2009)
J Am Coll Cardiol
, vol.54
-
-
Simonneau, G.1
Robbins, I.M.2
Beghetti, M.3
Channick, R.N.4
Delcroix, M.5
Denton, C.P.6
Elliott, C.G.7
Gaine, S.P.8
Gladwin, M.T.9
Jing, Z.C.10
Krowka, M.J.11
Langleben, D.12
Nakahashi, N.13
Souza, R.14
-
8
-
-
34547627296
-
The effects of hypoxia on-the cells of the pulmonary vasculature
-
DOI 10.1183/09031936.00128706
-
Pak O, Aldashev A, Welsh D, Peacock A. The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J. 2007;30:364-372. (Pubitemid 47201724)
-
(2007)
European Respiratory Journal
, vol.30
, Issue.2
, pp. 364-372
-
-
Pak, O.1
Aldashev, A.2
Welsh, D.3
Peacock, A.4
-
9
-
-
0032491187
-
+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
-
Yuan JX, Aldinger AM, Juhaszova M, Wang J, Conte JV Jr, Gaine SP, Orens JB, Rubin LJ. Dysfunctional voltage-gated Ḱchannels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension. Circulation. 1998;98:1400-1406. (Pubitemid 28462800)
-
(1998)
Circulation
, vol.98
, Issue.14
, pp. 1400-1406
-
-
Yuan, J.X.-J.1
Aldinger, A.M.2
Juhaszova, M.3
Wang, J.4
Conte Jr., J.V.5
Gaine, S.P.6
Orens, J.B.7
Rubin, L.J.8
-
10
-
-
34347265735
-
Potassium channel diversity in the pulmonary arteries and pulmonary veins: Implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension
-
DOI 10.1016/j.pharmthera.2007.03.014, PII S0163725807000769
-
Bonnet S, Archer SL. Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension. Pharmacol Ther. 2007;115:56-69. (Pubitemid 46992809)
-
(2007)
Pharmacology and Therapeutics
, vol.115
, Issue.1
, pp. 56-69
-
-
Bonnet, S.1
Archer, S.L.2
-
11
-
-
0028060499
-
Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia
-
Li H, Chen SJ, Chen YF, Meng QC, Durand J, Oparil S, Elton TS. Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia. J Appl Physiol. 1994;77:1451-1459. (Pubitemid 24299403)
-
(1994)
Journal of Applied Physiology
, vol.77
, Issue.3
, pp. 1451-1459
-
-
Li, H.1
Chen, S.-J.2
Chen, Y.-F.3
Qing Cheng Meng4
Durand, J.5
Oparil, S.6
Elton, T.S.7
-
13
-
-
17444448272
-
Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension
-
Eddahibi S, Humbert M, Fadel E, Raffestin B, Darmon M, Capron F, Simonneau G, Dartevelle P, Hamon M, Adnot S. Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension. Chest. 2002;121:97S-98S. (Pubitemid 34248379)
-
(2002)
Chest
, vol.121
, Issue.3
-
-
Eddahibi, S.1
Humbert, M.2
Fadel, E.3
Raffestin, B.4
Darmon, M.5
Capron, F.6
Simonneau, G.7
Dartevelle, P.8
Hamon, M.9
Adnot, S.10
-
15
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5- hydroxytryptamine transporter gene
-
Eddahibi S, Hanoun N, Lanfumey L, Lesch KP, Raffestin B, Hamon M, Adnot S. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest. 2000;105: 1555-1562. (Pubitemid 30390306)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.11
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
Lesch, K.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
16
-
-
33750046289
-
CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro
-
DOI 10.1111/j.1440-1681.2006.04488.x
-
Yuan SH, Dai DZ, Guan L, Dai Y, Ji M. CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro. Clin Exp Pharmacol Physiol. 2006;33:1066-1072. (Pubitemid 44581569)
-
(2006)
Clinical and Experimental Pharmacology and Physiology
, vol.33
, Issue.11
, pp. 1066-1072
-
-
Yuan, S.-H.1
Dai, D.-Z.2
Guan, L.3
Dai, Y.4
Ji, M.5
-
17
-
-
0029947602
-
Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats
-
DOI 10.1016/0167-4781(96)00036-X
-
Geertman R, McMahon A, Sabban EL. Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats. Biochim Biophys Acta. 1996;1306:147-152. (Pubitemid 26153429)
-
(1996)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1306
, Issue.2-3
, pp. 147-152
-
-
Geertman, R.1
McMahon, A.2
Sabban, E.L.3
-
18
-
-
0032574745
-
ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases
-
DOI 10.1073/pnas.95.9.5156
-
Koseki T, Inohara N, Chen S, Nunez G. ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases. Proc Natl Acad Sci USA. 1998;95:5156-5160. (Pubitemid 28208567)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.9
, pp. 5156-5160
-
-
Koseki, T.1
Inohara, N.2
Chen, S.3
Nunez, G.4
-
19
-
-
4644354531
-
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions
-
DOI 10.1016/j.molcel.2004.08.020, PII S1097276504004824
-
Nam YJ, Mani K, Ashton AW, Peng CF, Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ, Kitsis RN. Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions. Mol Cell. 2004;15:901-912. (Pubitemid 39277987)
-
(2004)
Molecular Cell
, vol.15
, Issue.6
, pp. 901-912
-
-
Nam, Y.-J.1
Mani, K.2
Ashton, A.W.3
Peng, C.-F.4
Krishnamurthy, B.5
Hayakawa, Y.6
Lee, P.7
Korsmeyer, S.J.8
Kitsis, R.N.9
-
20
-
-
2442716574
-
Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation
-
DOI 10.1074/jbc.M400695200
-
Gustafsson AB, Tsai JG, Logue SE, Crow MT, Gottlieb RA. Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. J Biol Chem. 2004;279:21233-21238. (Pubitemid 38656528)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 21233-21238
-
-
Gustafsson, A.B.1
Tsai, J.G.2
Logue, S.E.3
Crow, M.T.4
Gottlieb, R.A.5
-
21
-
-
0033539994
-
ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells
-
Ekhterae D, Lin Z, Lundberg MS, Crow MT, Brosius FC III, Nunez G. ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells. Circ Res. 1999;85:e70-e7.
-
(1999)
Circ Res
, vol.85
-
-
Ekhterae, D.1
Lin, Z.2
Lundberg, M.S.3
Crow, M.T.4
Brosius Iii, F.C.5
Nunez, G.6
-
22
-
-
0035823571
-
The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function
-
Neuss M, Monticone R, Lundberg MS, Chesley AT, Fleck E, Crow MT. The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function. J Biol Chem. 2001;276:33915-33922.
-
(2001)
J Biol Chem
, vol.276
, pp. 33915-33922
-
-
Neuss, M.1
Monticone, R.2
Lundberg, M.S.3
Chesley, A.T.4
Fleck, E.5
Crow, M.T.6
-
23
-
-
20444483234
-
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
-
DOI 10.1172/JCI23203
-
McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, Bonnet S, Puttagunta L, Michelakis ED. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest. 2005;115:1479-1491. (Pubitemid 40814657)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1479-1491
-
-
McMurtry, M.S.1
Archer, S.L.2
Altieri, D.C.3
Bonnet, S.4
Haromy, A.5
Harry, G.6
Bonnet, S.7
Puttagunta, L.8
Michelakis, E.D.9
-
24
-
-
0041859249
-
Attenuation of chronic hypoxic pulmonary hypertension by simvastatin
-
Girgis RE, Li X, Zhan X, Garcia JG, Tuder RM, Hassoun PM, Johns RA. Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Respir Cell Mol Biol. 2003;285:H938-H945. (Pubitemid 37048146)
-
(2003)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.285
, Issue.3
-
-
Girgis, R.E.1
Li, D.2
Zhan, X.3
Garcia, J.G.N.4
Tuder, R.M.5
Hassoun, P.M.6
Johns, R.A.7
-
25
-
-
40749090043
-
PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation
-
DOI 10.1152/ajplung.00245.2007
-
Hemnes AR, Zaiman A, Champion HC. PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation. Am J Physiol Lung Cell Mol Physiol. 2008;294:L24-L33. (Pubitemid 351380315)
-
(2008)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.294
, Issue.1
-
-
Hemnes, A.R.1
Zaiman, A.2
Champion, H.C.3
-
26
-
-
20044363270
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
-
DOI 10.1038/nm1175
-
Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med. 2005;11:214-222. (Pubitemid 40321358)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 214-222
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Belardi, D.4
Ren, S.5
Rodriguez, E.R.6
Bedja, D.7
Gabrielson, K.L.8
Wang, Y.9
Kass, D.A.10
-
27
-
-
20044392926
-
ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance [3]
-
DOI 10.1038/sj.cdd.4401631
-
Mercier I, Vuolo M, Madan R, Xue X, Levalley AJ, Ashton AW, Jasmin JF, Czaja MT, Lin EY, Armstrong RC, Pollard KW, Kitsis RN. ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo-and radiation-resistance. Cell Death Differ. 2005;12:682-686. (Pubitemid 40767172)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.6
, pp. 682-686
-
-
Mercier, I.1
Vuolo, M.2
Madan, R.3
Xue, X.4
Levalley, A.J.5
Ashton, A.W.6
Jasmin, J.-F.7
Czaja, M.T.8
Lin, E.Y.9
Armstrong, R.C.10
Pollard, J.W.11
Kitsis, R.N.12
-
28
-
-
77953495653
-
Induction of the apoptosis inhibitor ARC by Ras in human cancers
-
Wu L, Nam YJ, Kung G, Crow MT, Kitsis RN. Induction of the apoptosis inhibitor ARC by Ras in human cancers. J Biol Chem. 2010;285: 19235-19245.
-
(2010)
J Biol Chem
, vol.285
, pp. 19235-19245
-
-
Wu, L.1
Nam, Y.J.2
Kung, G.3
Crow, M.T.4
Kitsis, R.N.5
-
29
-
-
45849097197
-
ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer
-
Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN. ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer. Cell Cycle. 2008;7:1640-1647. (Pubitemid 351881332)
-
(2008)
Cell Cycle
, vol.7
, Issue.11
, pp. 1640-1647
-
-
Mercier, I.1
Vuolo, M.2
Jasmin, J.-F.3
Medina, C.M.4
Williams, M.5
Mariadason, J.M.6
Qian, H.7
Xue, X.8
Pestell, R.G.9
Lisanti, M.P.10
Kitsis, R.N.11
-
30
-
-
78751694922
-
Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML
-
Carter BZ, Qui YH, Zhang N, Coombes KR, Mak DH, Thomas DA, Ravandi F, Kantarjian HM, Andreeff M, Kornblau SM. 2011 Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML. Blood. 2011;117: 780-787.
-
(2011)
Blood
, vol.117
, pp. 780-787
-
-
Carter, B.Z.1
Qui, Y.H.2
Zhang, N.3
Coombes, K.R.4
Mak, D.H.5
Thomas, D.A.6
Ravandi, F.7
Kantarjian, H.M.8
Andreeff, M.9
Kornblau, S.M.10
-
31
-
-
18844411578
-
v channel gene expression in rat distal pulmonary artery
-
DOI 10.1152/ajplung.00379.2004
-
Wang J, Weigand L, Wang W, Sylvester JT, Shimoda LA. Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery. Am J Physiol Lung Cell Mol Physiol. 2005;288:L1049-L1058. (Pubitemid 40695430)
-
(2005)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.288
, Issue.6
-
-
Wang, J.1
Weigand, L.2
Wang, W.3
Sylvester, J.T.4
Shimoda, L.A.5
-
32
-
-
0032104119
-
+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes
-
Archer SL, Souil E, Nh-Xuan AT, Schremmer B, Mercier JC, El YA, Nguyen-Huu L, Reeve HL, Hampl V. Molecular identification of the role of voltage-gated Ḱchannels, Kv15 and Kv21, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes. J Clin Invest. 1998;101:2319-2330. (Pubitemid 28270426)
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.11
, pp. 2319-2330
-
-
Archer, S.L.1
Souil, E.2
Tuan Dinh-Xuan, A.3
Schremmer, B.4
Mercier, J.-C.5
Yaagoubi, A.E.6
Nguyen-Huu, L.7
Reeve, H.L.8
Hampl, V.9
-
33
-
-
40349110969
-
Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: Pharmacotherapeutic implications
-
DOI 10.1038/sj.bjp.0707635, PII 0707635
-
Burg ED, Remillard CV, Yuan JX. Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications. Br J Pharmacol. 2008;153(Suppl 1):S99-S111. (Pubitemid 351341007)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.SUPPL. 1
-
-
Burg, E.D.1
Remillard, C.V.2
Yuan, J.X.-J.3
-
34
-
-
2942726402
-
+ channels in human pulmonary artery smooth muscle cell
-
DOI 10.1152/ajplung.00438.2003
-
Platoshyn O, Remillard CV, Fantozzi I, Mandegar M, Sison TT, Zhang S, Burg E, Yuan JX. Diversity of voltage-dependent Ḱchannels in human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2004;287:L226-L238. (Pubitemid 38787670)
-
(2004)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.287
, Issue.1
-
-
Platoshyn, O.1
Remillard, C.V.2
Fantozzi, I.3
Mandegar, M.4
Sison, T.T.5
Zhang, S.6
Burg, E.7
Yuan, J.X.-J.8
-
35
-
-
51849167730
-
The cancer paradigm of severe pulmonary arterial hypertension
-
Rai PR, Cool CD, King JA, Stevens T, Burns N, Winn RA, Kasper M, Voelkel NF. The cancer paradigm of severe pulmonary arterial hypertension. Am J Respir Crit Care Med. 2008;178:558-564.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 558-564
-
-
Rai, P.R.1
Cool, C.D.2
King, J.A.3
Stevens, T.4
Burns, N.5
Winn, R.A.6
Kasper, M.7
Voelkel, N.F.8
-
36
-
-
34547456414
-
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
-
DOI 10.1073/pnas.0610467104
-
Bonnet S, Rochefort G, Sutendra G, Archer SL, Harmony A, Webster L, Hashimoto K, Bonnet SN, Mickelakis ED. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci USA. 2007;104:11418-11423. (Pubitemid 47175155)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.27
, pp. 11418-11423
-
-
Bonnet, S.1
Rochefort, G.2
Sutendra, G.3
Archer, S.L.4
Haromy, A.5
Webster, L.6
Hashimoto, K.7
Bonnet, S.N.8
Michelakis, E.D.9
-
37
-
-
34249905501
-
L expression in lung vascular smooth muscle
-
DOI 10.1165/rcmb.2006-0359OC
-
Suzuki YJ, Nagase H, Wong CM, Kumar SV, Jain V, Park AM, Day RM. Regulation of Bcl-xL expression in lung vascular smooth muscle. Am J Respir Cell Mol Biol. 2007;36:678-687. (Pubitemid 46871422)
-
(2007)
American Journal of Respiratory Cell and Molecular Biology
, vol.36
, Issue.6
, pp. 678-687
-
-
Suzuki, Y.J.1
Nagase, H.2
Chi, M.W.3
Kumar, S.V.4
Jain, V.5
Park, A.-M.6
Day, R.M.7
-
38
-
-
38049144182
-
Regulation of p53 tetramerization and nuclear export by ARC
-
Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, Provenzano E, Ellis I, Figg N, Pinder S, Bennett MR, Caldas C, Kitsis RN. Regulation of p53 tetramerization and nuclear export by ARC. Proc Natl Acad Sci USA. 2007; 104:20826-20831.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20826-20831
-
-
Foo, R.S.1
Nam, Y.J.2
Ostreicher, M.J.3
Metzl, M.D.4
Whelan, R.S.5
Peng, C.F.6
Ashton, A.W.7
Fu, W.8
Mani, K.9
Chin, S.F.10
Provenzano, E.11
Ellis, I.12
Figg, N.13
Pinder, S.14
Bennett, M.R.15
Caldas, C.16
Kitsis, R.N.17
-
39
-
-
37849029183
-
P53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC
-
Li YZ, Lu DY, Tan WQ, Wang JX, Li PF. p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC. Mol Cell Biol. 2008;28:564-574.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 564-574
-
-
Li, Y.Z.1
Lu, D.Y.2
Tan, W.Q.3
Wang, J.X.4
Li, P.F.5
-
40
-
-
79955772507
-
P53 gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice
-
Mizuno S, Bogaard HJ, Kraskauskas D, Alhussaini A, Gomez-Arroyo J, Voelkel NF, Ishizaki T. p53 gene deficiency promotes hypoxia-induced pulmonary hypertension and vascular remodeling in mice. Am J Physiol Lung Cell Mol Physiol. 2011;300:L753-L761.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
-
-
Mizuno, S.1
Bogaard, H.J.2
Kraskauskas, D.3
Alhussaini, A.4
Gomez-Arroyo, J.5
Voelkel, N.F.6
Ishizaki, T.7
-
41
-
-
0037598635
-
+ currents
-
Ekhterae D, Platoshyn O, Zhang S, Remillard CV, Yuan JX. Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing Ḱcurrents. Am J Physiol Cell Physiol. 2003;284: C1405-C1410. (Pubitemid 36583381)
-
(2003)
American Journal of Physiology - Cell Physiology
, vol.284
, Issue.6
-
-
Ekhterae, D.1
Platoshyn, O.2
Zhang, S.3
Remillard, C.V.4
Yuan, J.X.-J.5
-
42
-
-
39149127581
-
+ channel expression in pulmonary arterial myocytes
-
DOI 10.1152/ajplung.00091.2007
-
Whitman EM, Pisarcik S, Luke T, Fallon M, Wang J, Sylvester JT, Semenza GL, Shimoda LA. Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated Ḱchannel expression in pulmonary artery myocytes. Am J Physiol Lung Cell Mol Physiol. 2008;294:L309-L318. (Pubitemid 351253367)
-
(2008)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.294
, Issue.2
-
-
Whitman, E.M.1
Pisarcik, S.2
Luke, T.3
Fallon, M.4
Wang, J.5
Sylvester, J.T.6
Semenza, G.L.7
Shimoda, L.A.8
-
43
-
-
0034811051
-
Bcl-2 decreases voltage-gated Ḱchannel activity and enhances survival in vascular smooth muscle cells
-
Ekhterae D, Platoshyn, O, Krick S, Ying Y, Sharon SS, Yuan J-X. Bcl-2 decreases voltage-gated Ḱchannel activity and enhances survival in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2001;281: C157-C165.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Ekhterae, D.1
Platoshyn, O.2
Krick, S.3
Ying, Y.4
Sharon, S.S.5
Yuan, J.-X.6
-
44
-
-
0037817310
-
Therapeutic targeting of the survivin pathway in cancer: Initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis
-
Blanc-Brude OP, Mesri M, Wall NR, Plescia J, Dohi T, Altieri DC. Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis. Clin Cancer Res. 2003;7:2683-2692. (Pubitemid 36842114)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.7
, pp. 2683-2692
-
-
Blanc-Brude, O.P.1
Mesri, M.2
Wall, N.R.3
Plescia, J.4
Dohi, T.5
Altieri, D.C.6
-
45
-
-
0032539673
-
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux
-
DOI 10.1073/pnas.95.4.1455
-
Shimuzu S, Eguchi Y, Kamiiki W, Funahashi Y, Mignon M, Lacronique V, Matsuda H, Tsujimoto Y. Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux. Proc Nat Acad Sci USA. 1998; 95:1455-1459. (Pubitemid 28103413)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.4
, pp. 1455-1459
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
Funahashi, Y.4
Mignon, A.5
Lacronique, V.6
Matsuda, H.7
Tsujimoto, Y.8
-
46
-
-
0037080541
-
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: Role of increased expression and activity of voltage-gated potassium channels
-
DOI 10.1161/hc0202.101974
-
Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation. 2002; 105:244-250. (Pubitemid 34084326)
-
(2002)
Circulation
, vol.105
, Issue.2
, pp. 244-250
-
-
Michelakis, E.D.1
McMurtry, M.S.2
Wu, X.-C.3
Dyck, J.R.B.4
Moudgil, R.5
Hopkins, T.A.6
Lopaschuk, G.D.7
Puttagunta, L.8
Waite, R.9
Archer, S.L.10
-
47
-
-
0037461359
-
2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats
-
DOI 10.1161/01.CIR.0000062688.76508.B3
-
Pozeg ZI, Michelakis ED, McMurtry MS, Thébaud B, Wu XC, Dyck JR, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL. In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation. 2003;107:2037-2044. (Pubitemid 36506080)
-
(2003)
Circulation
, vol.107
, Issue.15
, pp. 2037-2044
-
-
Pozeg, Z.I.1
Michelakis, E.D.2
McMurtry, S.3
Thebaud, B.4
Wu, X.-C.5
Dyck, J.R.B.6
Hashimoto, K.7
Wang, S.8
Moudgil, R.9
Harry, G.10
Sultanian, R.11
Koshal, A.12
Archer, S.L.13
-
48
-
-
33645522627
-
Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress
-
and the German Heart Network
-
Donath S, Li P, Willenbockel C, Al-Saadi N, Gross V, Willnow T, Bader M, Martin U, Bauersach J, Wollert KC and the German Heart Network. Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress. Circulation. 2006;113:1203-1212.
-
(2006)
Circulation
, vol.113
, pp. 1203-1212
-
-
Donath, S.1
Li, P.2
Willenbockel, C.3
Al-Saadi, N.4
Gross, V.5
Willnow, T.6
Bader, M.7
Martin, U.8
Bauersach, J.9
Wollert, K.C.10
|