Age-related retention of fiber cell nuclei and nuclear fragments in the lens cortices of multiple species

Molecular Vision

Volumn 17, Issue , 2011, Pages 2672-2684

  Pendergrass, William ^a   Zitnik, Galynn ^a   Urfer, Silvan R ^a   Wolf, Norman ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; DEOXYRIBONUCLEASE II; EOSIN; HEMATOXYLIN; MESSENGER RNA;

AGING; ANIMAL TISSUE; ARTICLE; CATARACT; CELL DIFFERENTIATION; CELL NUCLEUS; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DEGRADATION; DOG; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOFLUORESCENCE TEST; LENS FIBER; LENS NUCLEUS; LIGHT REFRACTION; MICROSCOPY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; QUANTITATIVE ANALYSIS; RAT; RHESUS MONKEY; SPECIES DIFFERENCE;

AGED; AGED, 80 AND OVER; AGING; ANIMALS; CATARACT; CELL NUCLEUS; DNA; DNA FRAGMENTATION; DOGS; ENDODEOXYRIBONUCLEASES; FEMALE; FIBROSIS; HAPLORHINI; HISTOCYTOCHEMISTRY; HUMANS; INDOLES; LENS CORTEX, CRYSTALLINE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MIDDLE AGED; RATS; RATS, INBRED BN; RESEARCH DESIGN; SPECIES SPECIFICITY;

EID: 83055198559     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Bassnett S. On the mechanism of organelle degradation in the vertebrate lens. Exp Eye Res 2009; 88:133-9. [PMID: 18840431]
2. De Maria A, Bassnett S. DNase IIbeta distribution and activity in the mouse lens. Invest Ophthalmol Vis Sci 2007; 48:5638-46. [PMID: 18055814]
3. Wolf N, Pendergrass W, Singh N, Swisshelm K, Schwartz J. Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression. Mol Vis 2008; 14:274-85. [PMID: 18334943]
4. Bassnett S. Lens organelle degradation. Exp Eye Res 2002; 74:1-6. [PMID: 11878813]
5. Bassnnett S, Kuszak JR, Reinisch L, Brown HG, Beebe DC. Intercellular communication between epithelial and fiber cells of the eye lens esterases. J Cell Sci 1994; 107:799-811. [PMID: 8056837]
6. Bassnett S. Fiber cell denucleation in the primate lens. Invest Ophthalmol Vis Sci 1997; 38:1678-87. [PMID: 9286256]
7. Bassnett S, McNulty R. The effect of elevated intraocular oxygen on organelle degradation in the embryonic chicken lens. J Exp Biol 2003; 206:4353-61. [PMID: 14581604]
8. Bassøe CF, Li N, Ragheb K, Lawler G, Sturgis J, Robinson JP. Investigations of phagosomes, mitochondria, and acidic granules in human neutrophils using fluorescent probes. Cytometry 2003; 51:21-9. [PMID: 12500294]
9. Michael R, van Marle J, Vrensen GF, van den Berg TJ. Changes in the refractive index of lens fibre membranes during maturation-impact on lens transparency. Exp Eye Res 2003; 77:93-9. [PMID: 12823992]
10. Vrensen GF. Early cortical lens opacities: a short overview. Acta Ophthalmol 2009; 87:602-10. [PMID: 19719805]
11. Clark JI. Order and disorder in the transparent media of the eye. Exp Eye Res 2004; 78:427-32. [PMID: 15106922]
12. Pendergrass WR, Penn PE, Possin DE, Wolf NS. Cellular debris and ROS in age-related cortical cataract are caused by inappropriate involution of the surface epithelial cells into the lens cortex. Mol Vis 2006; 12:712-24. [PMID: 16807531]
13. Pendergrass W, Zitnik G, Tsai R, Wolf N. X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts. Mol Vis 2010; 16:1496-513. [PMID: 20806081]
14. Pendergrass W, Penn P, Possin D, Wolf N. Accumulation of DNA, Nuclear and Mitochondrial Debris, and ROS at Sites of Age-Related Cortical Cataract in Mice. Invest Ophthalmol Vis Sci 2005; 46:4661-70. [PMID: 16303963]
15. Graw J, Löster J, Soewarto D, Fuchs H, Meyer B, Reis A, Wolf E, Balling R, Hrabé de Angelis M. Characterization of a mutation in the lens-specific MP70 encoding gene of the mouse leading to a dominant cataract. Exp Eye Res 2001; 73:867-76. [PMID: 11846517]
16. Graw J, Neuhäuser-Klaus A, Löster J, Favor J. A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. Invest Ophthalmol Vis Sci 2002; 43:236-40. [PMID: 11773036]
17. Graw J. Mouse models of cataract. J Genet 2009; 88:469-86. [PMID: 20090208]
18. Jun G, Guo H, Klein BE, Klein R, Wang JJ, Mitchell P, Miao H, Lee KE, Joshi T, Buck M, Chugha P, Bardenstein D, Klein AP, Bailey-Wilson JE, Gong X, Spector TD, Andrew T, Hammond CJ, Elston RC, Lyengar SK, Wang B. EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet 2009; 5:e1000584. [PMID: 19649315]
19. Perez-Castro AV, Tran VT, Nguyen-Huu MC. Defective lens fiber differentiation and pancreatic tumorigenesis caused by ectopic expression of the cellular retinoic acid-binding protein I. Development 1993; 119:363-75. [PMID: 8287793]
20. Fromm L, Overbeek PA. Inhibition of cell death by lensspecific overexpression of bcl-2 in transgenic mice. Dev Genet 1997; 20:276-87. [PMID: 9216067]
21. Zhang J, Li J, Huang C, Xue L, Peng Y, Fu Q, Gao L, Zhang J, Li W. Targeted knockout of the mouse betaB2-crystallin gene (Crybb2) induces age-related cataract. Invest Ophthalmol Vis Sci 2008; 49:5476-83. [PMID: 18719080]
22. Uga S, Kohara M, Ishikawa S. Morphological study of agerelated changes in mouse lens. Jpn J Ophthalmol 1983; 27:157-65. [PMID: 6855009]
23. Puk O, Ahmad N, Wagner S, Hrabé de Angelis M, Graw J. First mutation in the betaA2-crystallin encoding gene is associated with small lenses and age-related cataracts. Invest Ophthalmol Vis Sci 2011; 52:2571-6. [PMID: 21212184]
24. Sinha D, Wyatt MK, Sarra R, Jaworski C, Slingsby C, Thaung C, Pannell L, Robison WG, Favor J, Lyon M, Wistow G. A temperature-sensitive mutation of Crygs in the murine Opj cataract. J Biol Chem 2001; 276:9308-15. [PMID: 11121426]
25. Nagata S. DNA degradation in development and programmed cell death. Annu Rev Immunol 2005; 23:853-75. [PMID: 15771588]
26. Wolf NS, Li Y, Pendergrass W, Schmeider C, Turturro A. Normal mouse and rat strains as models for age-related cataract and the effect of caloric restriction on its development. Exp Eye Res 2000; 70:683-92. [PMID: 10870527]
27. Wolf N, Galecki A, Lipman R, Chen S, Smith-Wheelock M, Burke D, Miller R. Quantitative trait locus mapping for agerelated cataract severity and synechia prevalence using fourway cross mice. Invest Ophthalmol Vis Sci 2004; 45:1922-9. [PMID: 15161859]
28. Ruiz-Ederra J, Verkman AS. Accelerated cataract formation and reduced lens epithelial water permeability in aquaporin-1-deficient mice. Invest Ophthalmol Vis Sci 2006; 47:3960-7. [PMID: 16936111]
29. Gelatt KN, Mackay EO. Prevalence of primary breed-related cataracts in the dog in North America. Vet Ophthalmol 2005; 8:101-11. [PMID: 15762923]
30. Fernandes A, Bradley DV, Tigges M, Tigges J, Herndon JG. Ocular measurements throughout the adult life span of rhesus monkeys. Invest Ophthalmol Vis Sci 2003; 44:2373-80. [PMID: 12766033]
31. Chew EY, Kim J, Sperduto RD, Datiles MB 3rd, Coleman HR, Thompson DJ, Milton RC, Clayton JA, Hubbard LD, Danis RP, Ferris FL 3rd. Evaluation of the age-related eye disease study clinical lens grading system AREDS report No. 31. Ophthalmology 2010; 117:2112-9. e3. [PMID: 20561686]
32. Klein BE, Meuer SM, Lee KE, Klein R. Retrodots in the lens in the Beaver Dam Eye Study cohort. Ophthalmology 2010; 117:1889-93. [PMID: 20570366]
33. Massof RW. A model of the prevalence and incidence of low vision and blindness among adults in the U.S. Optom Vis Sci 2002; 79:31-8. [PMID: 11828896]
34. Jackson Laboratory. electronic site, Harrison lab. Baseline life span data: commonly used JAX Mice and crosses. Jackson Laboratory: Bar Harbor, MN; 2011.
35. Nishimoto S, Kawane K, Watanabe-Fukunaga R, Fukuyama H, Ohsawa Y, Uchiyama Y, Hashida N, Ohguro N, Tano Y, Morimoto T, Fukuda Y, Nagata S. Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens. Nature 2003; 424:1071-4. [PMID: 12944971]
36. Urfer SR, Greer K, Wolf NS. Age-related cataract in dogs: a biomarker for life span and its relation to body size. Age (Dordr) 2010; 33:451-60. [PMID: 20607428]
37. Nagai N, Takeuchi N, Kamei A, Ito Y. Involvement of DNase II-like acid DNase in the cataract formation of the UPL rat and the Shumiya cataract rat. Biol Pharm Bull 2006; 29:2367-71. [PMID: 17142965]
38. Nakahara M, Nagasaka A, Koike M, Uchida K, Kawane K, Uchiyama Y, Nagata S. Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens. FEBS J 2007; 274:3055-64. [PMID: 17509075]
39. Costello MJ, Johnsen S, Gilliland KO, Freel CD, Fowler WC. Predicted light scattering from particles observed in human age-related nuclear cataracts using mie scattering theory. Invest Ophthalmol Vis Sci 2007; 48:303-12. [PMID: 17197547]
40. Gilliland KO, Freel CD, Johnsen S, Craig Fowler W, Costello MJ. Distribution, spherical structure and predicted Mie scattering of multilamellar bodies in human age-related nuclear cataracts. Exp Eye Res 2004; 79:563-76. [PMID: 15381040]
41. Wride MA. Minireview: apoptosis as seen through a lens. Apoptosis 2000; 5:203-9. [PMID: 11225840]
42. Wride MA. Lens fibre cell differentiation and organelle loss: many paths lead to clarity. Philos Trans R Soc Lond B Biol Sci 2011; 366:1219-33. [PMID: 21402582]
43. Michael R, Bron AJ. The ageing lens and cataract: a model of normal and pathological ageing. Philos Trans R Soc Lond B Biol Sci 2011; 366:1278-92. [PMID: 21402586]