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Volumn 20, Issue 3, 1997, Pages 276-287

Inhibition of cell death by lens-specific overexpression of bcl-2 in transgenic mice

Author keywords

Apoptosis; bcl 2; Crystallin; Lens; p53; Transgenic

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CHROMOSOME TRANSLOCATION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; IN SITU HYBRIDIZATION; LENS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RECEPTOR UPREGULATION; TUMOR SUPPRESSOR GENE;

EID: 0030745877     PISSN: 0192253X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6408(1997)20:3<276::AID-DVG10>3.0.CO;2-6     Document Type: Article
Times cited : (50)

References (63)
  • 2
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp TE, Wyatt S, Paterson HF, Davies AM (1993): The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73:295-307.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 3
  • 4
    • 0029949082 scopus 로고    scopus 로고
    • bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations
    • Chen J, Flannery JG, LaVail MM, Steinberg RH, Xu J (1996): bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proc Natl Acad Sci USA 93:7042-7047.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7042-7047
    • Chen, J.1    Flannery, J.G.2    LaVail, M.M.3    Steinberg, R.H.4    Xu, J.5
  • 5
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou SK, Rao L, White E (1994): Bcl-2 blocks p53-dependent apoptosis. Mol Cell Biol 14:2556-2563.
    • (1994) Mol Cell Biol , vol.14 , pp. 2556-2563
    • Chiou, S.K.1    Rao, L.2    White, E.3
  • 7
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulm transcript resulting from the t(14; 18) translocation
    • Cleary ML, Smith SD, Sklar J (1986): Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulm transcript resulting from the t(14; 18) translocation. Cell 47:19-28.
    • (1986) Cell , vol.47 , pp. 19-28
    • Cleary, M.L.1    Smith, S.D.2    Sklar, J.3
  • 8
    • 0030220462 scopus 로고    scopus 로고
    • Bcl-2 regulates activation of apoptotic proteases in a cell-free system
    • Cosulich SC, Green S and Clarke PR (1996): Bcl-2 regulates activation of apoptotic proteases in a cell-free system. Curr Biol 6:997-1005.
    • (1996) Curr Biol , vol.6 , pp. 997-1005
    • Cosulich, S.C.1    Green, S.2    Clarke, P.R.3
  • 12
    • 0029395054 scopus 로고
    • Life and death by p53
    • Elledge RM, Lee W-H (1995): Life and death by p53. BioEssays 17:923-930.
    • (1995) BioEssays , vol.17 , pp. 923-930
    • Elledge, R.M.1    Lee, W.-H.2
  • 13
    • 0025785484 scopus 로고
    • Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein
    • Ewen M, Xing YE, Lawrence JB, Livingston JM (1991): Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell 66:1155-1164.
    • (1991) Cell , vol.66 , pp. 1155-1164
    • Ewen, M.1    Xing, Y.E.2    Lawrence, J.B.3    Livingston, J.M.4
  • 14
    • 0026722655 scopus 로고
    • Cooperative interaction between c-myc and bcl-2 proto-oncogenes
    • Fanidi A, Harrington EA, Evan GI (1992): Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 359:554-556.
    • (1992) Nature , vol.359 , pp. 554-556
    • Fanidi, A.1    Harrington, E.A.2    Evan, G.I.3
  • 15
    • 0026724311 scopus 로고
    • Structure and function of simian virus 40 large tumor antigen
    • Fanning E, Knippers R (1992): Structure and function of simian virus 40 large tumor antigen. Annu Rev Biochem 61:55-85.
    • (1992) Annu Rev Biochem , vol.61 , pp. 55-85
    • Fanning, E.1    Knippers, R.2
  • 16
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ (1988): Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 8:531-539.
    • (1988) Mol Cell Biol , vol.8 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine, A.J.6
  • 17
    • 0030033194 scopus 로고    scopus 로고
    • Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein
    • Fromm L, Overbeek PA (1996): Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein. Oncogene 12:69-75.
    • (1996) Oncogene , vol.12 , pp. 69-75
    • Fromm, L.1    Overbeek, P.A.2
  • 18
    • 0028071541 scopus 로고
    • The retinoblastoma binding-region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice
    • Fromm L, Shawlot W, Gunning K, Butel JS, Overbeek PA (1994): The retinoblastoma binding-region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice. Mol Cell Biol 14:6743-6754.
    • (1994) Mol Cell Biol , vol.14 , pp. 6743-6754
    • Fromm, L.1    Shawlot, W.2    Gunning, K.3    Butel, J.S.4    Overbeek, P.A.5
  • 20
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • Garcia I, Martinou I, Tsujimoto Y, Martinou J-C (1992): Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258:302-304.
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.-C.4
  • 21
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992): Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 22
    • 0028109983 scopus 로고
    • bcl-2 expression in human colorectal adenomas and carcinomas
    • Hague A, Moorghen M, Hicks D, Chapman M, Paraskeva C (1994): bcl-2 expression in human colorectal adenomas and carcinomas. Oncogene 9:3367-3370.
    • (1994) Oncogene , vol.9 , pp. 3367-3370
    • Hague, A.1    Moorghen, M.2    Hicks, D.3    Chapman, M.4    Paraskeva, C.5
  • 23
    • 0027142956 scopus 로고
    • Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins
    • Hannon GJ, Demetrick D, Beach D (1993): Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes Dev 7:2378-2391.
    • (1993) Genes Dev , vol.7 , pp. 2378-2391
    • Hannon, G.J.1    Demetrick, D.2    Beach, D.3
  • 24
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993): The p21 cdk-interacting protein Cipl is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 25
    • 0024535277 scopus 로고
    • Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation
    • Hinds P, Finlay C, Levine AJ (1989): Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J Virol 62:739-746.
    • (1989) J Virol , vol.62 , pp. 739-746
    • Hinds, P.1    Finlay, C.2    Levine, A.J.3
  • 26
    • 0028605481 scopus 로고
    • bcl-2 in cancer, development and apoptosis
    • Hockenbery DM (1994): bcl-2 in cancer, development and apoptosis. J Cell Sci 18:51-55.
    • (1994) J Cell Sci , vol.18 , pp. 51-55
    • Hockenbery, D.M.1
  • 29
    • 0028227260 scopus 로고
    • Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
    • Howes KA, Ransom N, Papermaster DS, Lasudry JG, Albert DM, Windle JJ (1994): Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev 8:1300-1310.
    • (1994) Genes Dev , vol.8 , pp. 1300-1310
    • Howes, K.A.1    Ransom, N.2    Papermaster, D.S.3    Lasudry, J.G.4    Albert, D.M.5    Windle, J.J.6
  • 31
  • 32
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko LJ, Prives C (1996): p53: Puzzle and paradigm. Genes Dev 10:1054-1072.
    • (1996) Genes Dev , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 33
    • 0024431245 scopus 로고
    • High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene
    • Lavigueur A, Maltby V, Mock D, Rossant J, Pawson T, Bernstein A (1989): High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol Cell Biol 9:3982-3991.
    • (1989) Mol Cell Biol , vol.9 , pp. 3982-3991
    • Lavigueur, A.1    Maltby, V.2    Mock, D.3    Rossant, J.4    Pawson, T.5    Bernstein, A.6
  • 35
    • 0027326586 scopus 로고
    • The tumor suppressor genes
    • Levine AJ (1993): The tumor suppressor genes. Annu Rev Biochem 62:623-651.
    • (1993) Annu Rev Biochem , vol.62 , pp. 623-651
    • Levine, A.J.1
  • 36
    • 0027262606 scopus 로고
    • Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
    • Lowe SW, Ruley HE (1993): Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev 7:535-545.
    • (1993) Genes Dev , vol.7 , pp. 535-545
    • Lowe, S.W.1    Ruley, H.E.2
  • 38
    • 0021616838 scopus 로고
    • UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed cells
    • Maltzman W, Czyzyk L (1984): UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed cells. Mol Cell Biol 4:1689-1694.
    • (1984) Mol Cell Biol , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 39
    • 0028020522 scopus 로고
    • Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis
    • Marin MC, Hsu B, Meyn RE, Donehower LA, El-Naggar AK, McDonnell TJ (1994): Evidence that p53 and bcl-2 are regulators of a common cell death pathway important for in vivo lymphomagenesis. Oncogene 9:3107-3112.
    • (1994) Oncogene , vol.9 , pp. 3107-3112
    • Marin, M.C.1    Hsu, B.2    Meyn, R.E.3    Donehower, L.A.4    El-Naggar, A.K.5    McDonnell, T.J.6
  • 40
    • 0017903759 scopus 로고
    • Cell division, cell elongation and distribution of α-, β- and δ-crystallins in the rat lens
    • McAvoy JW (1978): Cell division, cell elongation and distribution of α-, β-and δ-crystallins in the rat lens. J Embryol Exp Morphol 44:149-165.
    • (1978) J Embryol Exp Morphol , vol.44 , pp. 149-165
    • McAvoy, J.W.1
  • 41
    • 0026053958 scopus 로고
    • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
    • McDonnell TJ, Korsmeyer SJ (1991): Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature 349:254-256.
    • (1991) Nature , vol.349 , pp. 254-256
    • McDonnell, T.J.1    Korsmeyer, S.J.2
  • 42
    • 0024521441 scopus 로고
    • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
    • McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKearn JP, Korsmeyer SJ (1989): bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57:79-88.
    • (1989) Cell , vol.57 , pp. 79-88
    • McDonnell, T.J.1    Deane, N.2    Platt, F.M.3    Nunez, G.4    Jaeger, U.5    McKearn, J.P.6    Korsmeyer, S.J.7
  • 43
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human Bax gene
    • Miyashita T, Reed JC (1995): Tumor suppressor p53 is a direct transcriptional activator of the human Bax gene. Cell 80:293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 46
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser SD, Williams BO, Jacks T, DePinho RA (1994): p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371:72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 47
    • 0027166048 scopus 로고
    • bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993): bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 48
    • 0022351502 scopus 로고
    • Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine αA-crystallin promoter in transgenic mice
    • Overbeek PA, Chepelinsky AB, Khillan JS, Piatigorsky J, Westphal H (1985): Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine αA-crystallin promoter in transgenic mice. Proc Natl Acad Sci USA 82:7815-7819.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7815-7819
    • Overbeek, P.A.1    Chepelinsky, A.B.2    Khillan, J.S.3    Piatigorsky, J.4    Westphal, H.5
  • 49
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan H, Griep AE (1994): Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development. Genes Dev 8:1285-1299.
    • (1994) Genes Dev , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 50
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • Pan H, Griep AE (1995): Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev 9:2157-2169.
    • (1995) Genes Dev , vol.9 , pp. 2157-2169
    • Pan, H.1    Griep, A.E.2
  • 51
    • 0019786296 scopus 로고
    • Lens differentiation in vertebrates: A review of cellular and molecular features
    • Piatigorsky J (1981): Lens differentiation in vertebrates: A review of cellular and molecular features. Differentiation 19:134-153.
    • (1981) Differentiation , vol.19 , pp. 134-153
    • Piatigorsky, J.1
  • 53
    • 0029610005 scopus 로고
    • Expression of a truncated FGF receptor results in defective lens development in transgenic mice
    • Robinson ML, MacMillan-Crow LA, Thompson JA, Overbeek PA (1995b): Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development 121:3959-3967.
    • (1995) Development , vol.121 , pp. 3959-3967
    • Robinson, M.L.1    MacMillan-Crow, L.A.2    Thompson, J.A.3    Overbeek, P.A.4
  • 54
    • 0023779204 scopus 로고
    • Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma
    • Seto M, Jaeger U, Hockett BD, Graninger W, Bennett S, Goldman P, Korsmeyer SJ (1988): Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J 7:123-131.
    • (1988) EMBO J , vol.7 , pp. 123-131
    • Seto, M.1    Jaeger, U.2    Hockett, B.D.3    Graninger, W.4    Bennett, S.5    Goldman, P.6    Korsmeyer, S.J.7
  • 55
    • 0026523778 scopus 로고
    • Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line
    • Shaw P, Bovey R, Tardy S, Sahli R, Sordat B, Costa J (1992): Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci USA 89:4495-4499.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4495-4499
    • Shaw, P.1    Bovey, R.2    Tardy, S.3    Sahli, R.4    Sordat, B.5    Costa, J.6
  • 56
    • 0024947938 scopus 로고
    • Insertional inactivation of the downless gene in a family of transgenic mice
    • Shawlot W, Siciliano MJ, Stallings RL, Overbeek PA (1989): Insertional inactivation of the downless gene in a family of transgenic mice. Mol Biol Med 6:299-307.
    • (1989) Mol Biol Med , vol.6 , pp. 299-307
    • Shawlot, W.1    Siciliano, M.J.2    Stallings, R.L.3    Overbeek, P.A.4
  • 62
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin X-M, Oltvai ZN, Korsmeyer SJ (1994): BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369:321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.-M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 63
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M (1991): Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352:345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


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