Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and α-hydroxy acid residue containing peptides

Chemistry - A European Journal

Volumn 8, Issue 18, 2002, Pages 4285-4291

  Rijkers, Dirk T S ^a   Höppener, Jo W M ^b   Posthuma, George ^b   Lips, Cornelis J M ^b   Liskamp, Rob M J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Aggregation; Amyloid; Peptides; Peptidomimetics; Protein modifications

Indexed keywords

AMINO ACIDS; DISEASES; ELECTRON MICROSCOPY; ENZYME INHIBITION; ESTERS; GENES; INFRARED SPECTROSCOPY; MUTAGENESIS;

PEPTIDES;

ENZYMES;

2 HYDROXYACID; ALKYL GROUP; AMIDE; AMINO ACID; AMINO ACID DERIVATIVE; AMYLIN; AMYLOID; ESTER; PEPTIDE; PEPTIDE DERIVATIVE; POLYPEPTIDE; PROTEIN DERIVATIVE;

ALKYLATION; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CHEMICAL BOND; CHEMISTRY; CREUTZFELDT JAKOB DISEASE; ELECTRON MICROSCOPY; HUMAN; INFRARED SPECTROSCOPY; MOLECULAR GENETICS; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; ULTRASTRUCTURE;

ALKYLATION; AMINO ACID SEQUENCE; AMINO ACIDS; AMYLOID; HUMANS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 0037120160     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20020916)8:18<4285::AID-CHEM4285>3.0.CO;2-0     Document Type: Article

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