Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for s -adenosylmethionine: Methyl transfer by S N2 displacement and radical generation

Journal of the American Chemical Society

Volumn 133, Issue 49, 2011, Pages 19586-19589

  Grove, Tyler L ^a   Radle, Matthew I ^a   Krebs, Carsten ^a   Booker, Squire J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON ATOMS; COFACTORS; CYS RESIDUES; METHYL GROUP; METHYL TRANSFERS; RADICAL GENERATION; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; SYNTHASES; WILD TYPES;

ALKYLATION; AMINO ACIDS; ESCHERICHIA COLI; FUNCTIONAL GROUPS; IRON; PROTEINS; RNA;

BIOSYNTHESIS;

CFR PROTEIN; CYSTEINE; IRON; RLMN PROTEIN; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATION; CATALYST; ENZYME ACTIVITY; ENZYME RECONSTITUTION; ESCHERICHIA COLI; PROTEIN ENGINEERING; WILD TYPE;

BACTERIAL PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IRON-SULFUR PROTEINS; METHYLTRANSFERASES; MODELS, MOLECULAR; S-ADENOSYLMETHIONINE; STAPHYLOCOCCUS AUREUS;

EID: 83055179165     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja207327v     Document Type: Article

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