-
1
-
-
33646380409
-
The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides
-
Abramov A.Y., Duchen M.R. The role of an astrocytic NADPH oxidase in the neurotoxicity of amyloid beta peptides. Philos Trans R Soc Lond B Biol Sci 2005, 360:2309-2314.
-
(2005)
Philos Trans R Soc Lond B Biol Sci
, vol.360
, pp. 2309-2314
-
-
Abramov, A.Y.1
Duchen, M.R.2
-
2
-
-
8144223671
-
RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
-
Arancio O., Zhang H.P., Chen X., Lin C., Trinchese F., Puzzo D., Liu S., Hegde A., Yan S.F., Stern A., Luddy J.S., Lue L.F., Walker D.G., Roher A., Buttini M., Mucke L., Li W., Schmidt A.M., Kindy M., Hyslop P.A., Stern D.M., Du Yan S.S. RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. EMBO J 2004, 23:4096-4105.
-
(2004)
EMBO J
, vol.23
, pp. 4096-4105
-
-
Arancio, O.1
Zhang, H.P.2
Chen, X.3
Lin, C.4
Trinchese, F.5
Puzzo, D.6
Liu, S.7
Hegde, A.8
Yan, S.F.9
Stern, A.10
Luddy, J.S.11
Lue, L.F.12
Walker, D.G.13
Roher, A.14
Buttini, M.15
Mucke, L.16
Li, W.17
Schmidt, A.M.18
Kindy, M.19
Hyslop, P.A.20
Stern, D.M.21
Du Yan, S.S.22
more..
-
3
-
-
0033105874
-
NADPH oxidase: an update
-
Babior B.M. NADPH oxidase: an update. Blood 1999, 93:1464-1476.
-
(1999)
Blood
, vol.93
, pp. 1464-1476
-
-
Babior, B.M.1
-
4
-
-
3042836549
-
The nature and effects of cortical microvascular pathology in aging and Alzheimer's disease
-
Bailey T.L., Rivara C.B., Rocher A.B., Hof P.R. The nature and effects of cortical microvascular pathology in aging and Alzheimer's disease. Neurol Res 2004, 26:573-578.
-
(2004)
Neurol Res
, vol.26
, pp. 573-578
-
-
Bailey, T.L.1
Rivara, C.B.2
Rocher, A.B.3
Hof, P.R.4
-
5
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J.B., Lesley R., Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994, 77:817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
6
-
-
0031882236
-
[Oxidative stress in the pathogenesis of Alzheimer's disease and antioxidant neuroprotection]
-
Behl C., Holsboer F. [Oxidative stress in the pathogenesis of Alzheimer's disease and antioxidant neuroprotection]. Fortschr Neurol Psychiatr 1998, 66:113-121.
-
(1998)
Fortschr Neurol Psychiatr
, vol.66
, pp. 113-121
-
-
Behl, C.1
Holsboer, F.2
-
7
-
-
67349142021
-
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
-
Bell R.D., Zlokovic B.V. Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol 2009, 118:103-113.
-
(2009)
Acta Neuropathol
, vol.118
, pp. 103-113
-
-
Bell, R.D.1
Zlokovic, B.V.2
-
8
-
-
0034603407
-
Agrin and microvascular damage in Alzheimer's disease
-
Berzin T.M., Zipser B.D., Rafii M.S., Kuo-Leblanc V., Yancopoulos G.D., Glass D.J., Fallon J.R., Stopa E.G. Agrin and microvascular damage in Alzheimer's disease. Neurobiol Aging 2000, 21:349-355.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 349-355
-
-
Berzin, T.M.1
Zipser, B.D.2
Rafii, M.S.3
Kuo-Leblanc, V.4
Yancopoulos, G.D.5
Glass, D.J.6
Fallon, J.R.7
Stopa, E.G.8
-
9
-
-
0031004788
-
Amyloid β-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells
-
Blanc E.M., Toborek M., Mark R.J., Hennig B., Mattson M.P. Amyloid β-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells. J Neurochem 1997, 68:1870-1881.
-
(1997)
J Neurochem
, vol.68
, pp. 1870-1881
-
-
Blanc, E.M.1
Toborek, M.2
Mark, R.J.3
Hennig, B.4
Mattson, M.P.5
-
10
-
-
0037111156
-
Microvascular damage and platelet abnormalities in early Alzheimer's disease
-
Borroni B., Akkawi N., Martini G., Colciaghi F., Prometti P., Rozzini L., Di Luca M., Lenzi G.L., Romanelli G., Caimi L., Padovani A. Microvascular damage and platelet abnormalities in early Alzheimer's disease. J Neurol Sci 2002, 203-204:189-193.
-
(2002)
J Neurol Sci
, vol.203-204
, pp. 189-193
-
-
Borroni, B.1
Akkawi, N.2
Martini, G.3
Colciaghi, F.4
Prometti, P.5
Rozzini, L.6
Di Luca, M.7
Lenzi, G.L.8
Romanelli, G.9
Caimi, L.10
Padovani, A.11
-
11
-
-
0030721487
-
Brain microvascular changes in Alzheimer's disease and other dementias
-
Buee L., Hof P.R., Delacourte A. Brain microvascular changes in Alzheimer's disease and other dementias. Ann N Y Acad Sci 1997, 826:7-24.
-
(1997)
Ann N Y Acad Sci
, vol.826
, pp. 7-24
-
-
Buee, L.1
Hof, P.R.2
Delacourte, A.3
-
12
-
-
0042379916
-
The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
-
Cai H., Griendling K.K., Harrison D.G. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 2003, 24:471-478.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 471-478
-
-
Cai, H.1
Griendling, K.K.2
Harrison, D.G.3
-
13
-
-
77955060516
-
P4-182: inhibition of ABCG2 transport function by amyloid-beta peptide augments cellular oxidative stress and inflammatory gene expression in cells
-
Callaghan D., Bai J., Huang A., Vukic V., Xiong H., Jones A., Walker D., Leu L.F., Beach T.G., Sue L., Zhang W. P4-182: inhibition of ABCG2 transport function by amyloid-beta peptide augments cellular oxidative stress and inflammatory gene expression in cells. Alzheimers Dement 2008, 4:T724.
-
(2008)
Alzheimers Dement
, vol.4
-
-
Callaghan, D.1
Bai, J.2
Huang, A.3
Vukic, V.4
Xiong, H.5
Jones, A.6
Walker, D.7
Leu, L.F.8
Beach, T.G.9
Sue, L.10
Zhang, W.11
-
14
-
-
20444462454
-
RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling
-
Chaney M.O., Stine W.B., Kokjohn T.A., Kuo Y.M., Esh C., Rahman A., Luehrs D.C., Schmidt A.M., Stern D., Yan S.D., Roher A.E. RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling. Biochim Biophys Acta 2005, 1741:199-205.
-
(2005)
Biochim Biophys Acta
, vol.1741
, pp. 199-205
-
-
Chaney, M.O.1
Stine, W.B.2
Kokjohn, T.A.3
Kuo, Y.M.4
Esh, C.5
Rahman, A.6
Luehrs, D.C.7
Schmidt, A.M.8
Stern, D.9
Yan, S.D.10
Roher, A.E.11
-
15
-
-
0035884148
-
Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid
-
Cherny V.V., Henderson L.M., Xu W., Thomas L.L., DeCoursey T.E. Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid. J Physiol 2001, 535:783-794.
-
(2001)
J Physiol
, vol.535
, pp. 783-794
-
-
Cherny, V.V.1
Henderson, L.M.2
Xu, W.3
Thomas, L.L.4
DeCoursey, T.E.5
-
16
-
-
0028854465
-
Studies on lipid peroxidation and protein oxidation in the aging brain
-
Cini M., Moretti A. Studies on lipid peroxidation and protein oxidation in the aging brain. Neurobiol Aging 1995, 16:53-57.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 53-57
-
-
Cini, M.1
Moretti, A.2
-
17
-
-
33748951370
-
How do heart disease and stroke become risk factors for Alzheimer's disease?
-
de la Torre J.C. How do heart disease and stroke become risk factors for Alzheimer's disease?. Neurol Res 2006, 28:637-644.
-
(2006)
Neurol Res
, vol.28
, pp. 637-644
-
-
de la Torre, J.C.1
-
18
-
-
34147183707
-
Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease
-
Deane R., Zlokovic B.V. Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease. Curr Alzheimer Res 2007, 4:191-197.
-
(2007)
Curr Alzheimer Res
, vol.4
, pp. 191-197
-
-
Deane, R.1
Zlokovic, B.V.2
-
19
-
-
0035875962
-
Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal {alpha}7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease
-
Dineley K.T., Westerman M., Bui D., Bell K., Ashe K.H., Sweatt J.D. Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal {alpha}7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci 2001, 21:4125-4133.
-
(2001)
J Neurosci
, vol.21
, pp. 4125-4133
-
-
Dineley, K.T.1
Westerman, M.2
Bui, D.3
Bell, K.4
Ashe, K.H.5
Sweatt, J.D.6
-
20
-
-
3042710057
-
Vascular smooth muscle actin is reduced in alzheimer disease brain: a quantitative analysis
-
Ervin J.F., Pannell C., Szymanski M., Welsh-Bohmer K., Schmechel D.E., Hulette C.M. Vascular smooth muscle actin is reduced in alzheimer disease brain: a quantitative analysis. J Neuropathol Exp Neurol 2004, 63:735-741.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 735-741
-
-
Ervin, J.F.1
Pannell, C.2
Szymanski, M.3
Welsh-Bohmer, K.4
Schmechel, D.E.5
Hulette, C.M.6
-
21
-
-
0035047718
-
Cerebral microvascular pathology in aging and Alzheimer's disease
-
Farkas E., Luiten P.G. Cerebral microvascular pathology in aging and Alzheimer's disease. Prog Neurobiol 2001, 64:575-611.
-
(2001)
Prog Neurobiol
, vol.64
, pp. 575-611
-
-
Farkas, E.1
Luiten, P.G.2
-
22
-
-
0033639245
-
Beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1
-
Giri R., Shen Y., Stins M., Du Yan S., Schmidt A.M., Stern D., Kim K.S., Zlokovic B., Kalra V.K. Beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1. Am J Physiol Cell Physiol 2000, 279:C1772-C1781.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Giri, R.1
Shen, Y.2
Stins, M.3
Du Yan, S.4
Schmidt, A.M.5
Stern, D.6
Kim, K.S.7
Zlokovic, B.8
Kalra, V.K.9
-
23
-
-
33644649803
-
Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
-
Girouard H., Iadecola C. Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 2006, 100:328-335.
-
(2006)
J Appl Physiol
, vol.100
, pp. 328-335
-
-
Girouard, H.1
Iadecola, C.2
-
24
-
-
33847613885
-
Inflammatory processes in Alzheimer's disease
-
Heneka M.T., O'Banion M.K. Inflammatory processes in Alzheimer's disease. J Neuroimmunol 2007, 184:69-91.
-
(2007)
J Neuroimmunol
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O'Banion, M.K.2
-
25
-
-
38549138327
-
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant
-
Heumüller S., Wind S., Barbosa-Sicard E., Schmidt H.H., Busse R., Schröder K., Brandes R.P. Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant. Hypertension 2008, 51:211-217.
-
(2008)
Hypertension
, vol.51
, pp. 211-217
-
-
Heumüller, S.1
Wind, S.2
Barbosa-Sicard, E.3
Schmidt, H.H.4
Busse, R.5
Schröder, K.6
Brandes, R.P.7
-
26
-
-
54049089921
-
Amyloid-beta peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A2
-
Hicks J.B., Lai Y., Sheng W., Yang X., Zhu D., Sun G.Y., Lee J.C. Amyloid-beta peptide induces temporal membrane biphasic changes in astrocytes through cytosolic phospholipase A2. Biochim Biophys Acta 2008, 1778:2512-2519.
-
(2008)
Biochim Biophys Acta
, vol.1778
, pp. 2512-2519
-
-
Hicks, J.B.1
Lai, Y.2
Sheng, W.3
Yang, X.4
Zhu, D.5
Sun, G.Y.6
Lee, J.C.7
-
27
-
-
0031026879
-
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study
-
Hofman A., Ott A., Breteler M.M., Bots M.L., Slooter A.J., van Harskamp F., van Duijn C.N., Van Broeckhoven C., Grobbee D.E. Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam study. Lancet 1997, 349:151-154.
-
(1997)
Lancet
, vol.349
, pp. 151-154
-
-
Hofman, A.1
Ott, A.2
Breteler, M.M.3
Bots, M.L.4
Slooter, A.J.5
van Harskamp, F.6
van Duijn, C.N.7
Van Broeckhoven, C.8
Grobbee, D.E.9
-
28
-
-
34250665401
-
Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis
-
Hsu M.J., Hsu C.Y., Chen B.C., Chen M.C., Ou G., Lin C.H. Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis. J Neurosci 2007, 27:5719-5729.
-
(2007)
J Neurosci
, vol.27
, pp. 5719-5729
-
-
Hsu, M.J.1
Hsu, C.Y.2
Chen, B.C.3
Chen, M.C.4
Ou, G.5
Lin, C.H.6
-
29
-
-
0041816291
-
Cerebrovascular effects of amyloid-beta peptides: mechanisms and implications for Alzheimer's dementia
-
Iadecola C. Cerebrovascular effects of amyloid-beta peptides: mechanisms and implications for Alzheimer's dementia. Cell Mol Neurobiol 2003, 23:681-689.
-
(2003)
Cell Mol Neurobiol
, vol.23
, pp. 681-689
-
-
Iadecola, C.1
-
30
-
-
0029583225
-
Increased collagen content of cerebral microvessels in Alzheimer's disease
-
Kalaria R.N., Pax A.B. Increased collagen content of cerebral microvessels in Alzheimer's disease. Brain Res 1995, 705:349-352.
-
(1995)
Brain Res
, vol.705
, pp. 349-352
-
-
Kalaria, R.N.1
Pax, A.B.2
-
31
-
-
33751185543
-
The role of cytosolic phospholipase A2-alfa in regulation of phagocytic functions
-
Levy R. The role of cytosolic phospholipase A2-alfa in regulation of phagocytic functions. Biochim Biophys Acta Mol Cell Biol Lipids 2006, 1761:1323-1334.
-
(2006)
Biochim Biophys Acta Mol Cell Biol Lipids
, vol.1761
, pp. 1323-1334
-
-
Levy, R.1
-
32
-
-
14944361889
-
NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes
-
Liu Q., Kkang J.H., Zheng R.L. NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes. Cell Biochem Funct 2005, 23:93-100.
-
(2005)
Cell Biochem Funct
, vol.23
, pp. 93-100
-
-
Liu, Q.1
Kkang, J.H.2
Zheng, R.L.3
-
33
-
-
0034840664
-
Involvement of microglial receptor for advanced glycation endproducts (rage) in alzheimer's disease: identification of a cellular activation mechanism
-
Lue L.F., Walker D.G., Brachova L., Beach T.G., Rogers J., Schmidt A.M., Stern D.M., Yan S.D. Involvement of microglial receptor for advanced glycation endproducts (rage) in alzheimer's disease: identification of a cellular activation mechanism. Exp Neurol 2001, 171:29-45.
-
(2001)
Exp Neurol
, vol.171
, pp. 29-45
-
-
Lue, L.F.1
Walker, D.G.2
Brachova, L.3
Beach, T.G.4
Rogers, J.5
Schmidt, A.M.6
Stern, D.M.7
Yan, S.D.8
-
34
-
-
0032526423
-
Beta-amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and thp1 monocytes
-
McDonald D.R., Bamberger M.E., Combs C.K., Landreth G.E. Beta-amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and thp1 monocytes. J Neurosci 1998, 18:4451-4460.
-
(1998)
J Neurosci
, vol.18
, pp. 4451-4460
-
-
McDonald, D.R.1
Bamberger, M.E.2
Combs, C.K.3
Landreth, G.E.4
-
35
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci P., MacGarvey U., Beal M.F. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann Neurol 1994, 36:747-751.
-
(1994)
Ann Neurol
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
36
-
-
33750603049
-
Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease
-
Moses G.S., Jensen M.D., Lue L.F., Walker D.G., Sun A.Y., Simonyi A., Sun G.Y. Secretory PLA2-IIA: a new inflammatory factor for Alzheimer's disease. J Neuroinflammation 2006, 3:28.
-
(2006)
J Neuroinflammation
, vol.3
, pp. 28
-
-
Moses, G.S.1
Jensen, M.D.2
Lue, L.F.3
Walker, D.G.4
Sun, A.Y.5
Simonyi, A.6
Sun, G.Y.7
-
37
-
-
0036213281
-
Phospholipase A2
-
Murakami M., Kudo I. Phospholipase A2. J Biochem 2002, 131:285-292.
-
(2002)
J Biochem
, vol.131
, pp. 285-292
-
-
Murakami, M.1
Kudo, I.2
-
38
-
-
70849085456
-
MAPK, β-amyloid and synaptic dysfunction: the role of RAGE
-
Origlia N., Arancio O., Domenici L., Yan S.S. MAPK, β-amyloid and synaptic dysfunction: the role of RAGE. Expert Rev Neurother 2009, 9:1635-1645.
-
(2009)
Expert Rev Neurother
, vol.9
, pp. 1635-1645
-
-
Origlia, N.1
Arancio, O.2
Domenici, L.3
Yan, S.S.4
-
39
-
-
14044258771
-
NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide
-
Park L., Anrather J., Zhou P., Frys K., Pitstick R., Younkin S., Carlson G.A., Iadecola C. NADPH-oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid beta peptide. J Neurosci 2005, 25:1769-1777.
-
(2005)
J Neurosci
, vol.25
, pp. 1769-1777
-
-
Park, L.1
Anrather, J.2
Zhou, P.3
Frys, K.4
Pitstick, R.5
Younkin, S.6
Carlson, G.A.7
Iadecola, C.8
-
40
-
-
39549106246
-
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
-
Park L., Zhou P., Pitstick R., Capone C., Anrather J., Norris E.H., Younkin L., Younkin S., Carlson G., McEwen B.S., Iadecola C. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci U S A 2008, 105:1347-1352.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1347-1352
-
-
Park, L.1
Zhou, P.2
Pitstick, R.3
Capone, C.4
Anrather, J.5
Norris, E.H.6
Younkin, L.7
Younkin, S.8
Carlson, G.9
McEwen, B.S.10
Iadecola, C.11
-
41
-
-
33646130154
-
The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress
-
Riganti C., Costamagna C., Bosia A., Ghigo D. The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress. Toxicol Appl Pharmacol 2006, 212:179-187.
-
(2006)
Toxicol Appl Pharmacol
, vol.212
, pp. 179-187
-
-
Riganti, C.1
Costamagna, C.2
Bosia, A.3
Ghigo, D.4
-
42
-
-
20444383813
-
Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam study
-
Ruitenberg A., den Heijer T., Bakker S.L., van Swieten J.C., Koudstaal P.J., Hofman A., Breteler M.M. Cerebral hypoperfusion and clinical onset of dementia: the Rotterdam study. Ann Neurol 2005, 57:789-794.
-
(2005)
Ann Neurol
, vol.57
, pp. 789-794
-
-
Ruitenberg, A.1
den Heijer, T.2
Bakker, S.L.3
van Swieten, J.C.4
Koudstaal, P.J.5
Hofman, A.6
Breteler, M.M.7
-
43
-
-
0035847269
-
Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
-
Sasaki N., Toki S., Chowei H., Saito T., Nakano N., Hayashi Y., Takeuchi M., Makita Z. Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease. Brain Res 2001, 888:256-262.
-
(2001)
Brain Res
, vol.888
, pp. 256-262
-
-
Sasaki, N.1
Toki, S.2
Chowei, H.3
Saito, T.4
Nakano, N.5
Hayashi, Y.6
Takeuchi, M.7
Makita, Z.8
-
44
-
-
45249097300
-
Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons
-
Shelat P.B., Chalimoniuk M., Wang J.H., Strosznajder J.B., Lee J.C., Sun A.Y., Simonyi A., Sun G.Y. Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons. J Neurochem 2008, 106:45-55.
-
(2008)
J Neurochem
, vol.106
, pp. 45-55
-
-
Shelat, P.B.1
Chalimoniuk, M.2
Wang, J.H.3
Strosznajder, J.B.4
Lee, J.C.5
Sun, A.Y.6
Simonyi, A.7
Sun, G.Y.8
-
46
-
-
0025790342
-
Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
-
Smith C.D., Carney J.M., Starke-Reed P.E., Oliver C.N., Stadtman E.R., Floyd R.A., Markesbery W.R. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci U S A 1991, 88:10540-10543.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 10540-10543
-
-
Smith, C.D.1
Carney, J.M.2
Starke-Reed, P.E.3
Oliver, C.N.4
Stadtman, E.R.5
Floyd, R.A.6
Markesbery, W.R.7
-
47
-
-
0032588897
-
Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration
-
Stephenson D., Rash K., Smalstig B., Roberts E., Johnstone E., Sharp J., Panetta J., Little S., Kramer R., Clemens J. Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration. Glia 1999, 27:110-128.
-
(1999)
Glia
, vol.27
, pp. 110-128
-
-
Stephenson, D.1
Rash, K.2
Smalstig, B.3
Roberts, E.4
Johnstone, E.5
Sharp, J.6
Panetta, J.7
Little, S.8
Kramer, R.9
Clemens, J.10
-
48
-
-
0029657725
-
Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain
-
Stephenson D.T., Lemere C.A., Selkoe D.J., Clemens J.A. Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain. Neurobiol Dis 1996, 3:51-63.
-
(1996)
Neurobiol Dis
, vol.3
, pp. 51-63
-
-
Stephenson, D.T.1
Lemere, C.A.2
Selkoe, D.J.3
Clemens, J.A.4
-
49
-
-
34548121631
-
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases
-
Sun G.Y., Horrocks L.A., Farooqui A.A. The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases. J Neurochem 2007, 103:1-16.
-
(2007)
J Neurochem
, vol.103
, pp. 1-16
-
-
Sun, G.Y.1
Horrocks, L.A.2
Farooqui, A.A.3
-
50
-
-
1242297090
-
Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases
-
Sun G.Y., Xu J., Jensen M.D., Simonyi A. Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases. J Lipid Res 2004, 45:205-213.
-
(2004)
J Lipid Res
, vol.45
, pp. 205-213
-
-
Sun, G.Y.1
Xu, J.2
Jensen, M.D.3
Simonyi, A.4
-
51
-
-
0032487625
-
Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40
-
Suo Z., Tan J., Placzek A., Crawford F., Fang C., Mullan M. Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Res 1998, 807:110-117.
-
(1998)
Brain Res
, vol.807
, pp. 110-117
-
-
Suo, Z.1
Tan, J.2
Placzek, A.3
Crawford, F.4
Fang, C.5
Mullan, M.6
-
52
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction
-
Takuma K., Fang F., Zhang W., Yan S., Fukuzaki E., Du H., Sosunov A., McKhann G., Funatsu Y., Nakamichi N., Nagai T., Mizoguchi H., Ibi D., Hori O., Ogawa S., Stern D.M., Yamada K., Yan S.S. RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci U S A 2009, 106:20021-20026.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
Sosunov, A.7
McKhann, G.8
Funatsu, Y.9
Nakamichi, N.10
Nagai, T.11
Mizoguchi, H.12
Ibi, D.13
Hori, O.14
Ogawa, S.15
Stern, D.M.16
Yamada, K.17
Yan, S.S.18
-
53
-
-
0032851269
-
Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides
-
Tan J., Town T., Suo Z., Wu Y., Song S., Kundtz A., Kroeger J., Humphrey J., Crawford F., Mullan M. Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides. Brain Res Bull 1999, 50:143-148.
-
(1999)
Brain Res Bull
, vol.50
, pp. 143-148
-
-
Tan, J.1
Town, T.2
Suo, Z.3
Wu, Y.4
Song, S.5
Kundtz, A.6
Kroeger, J.7
Humphrey, J.8
Crawford, F.9
Mullan, M.10
-
54
-
-
62249200515
-
Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
-
Vukic V., Callaghan D., Walker D., Lue L.F., Liu Q.Y., Couraud P.O., Romero I.A., Weksler B., Stanimirovic D.B., Zhang W. Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiol Dis 2009, 34:95-106.
-
(2009)
Neurobiol Dis
, vol.34
, pp. 95-106
-
-
Vukic, V.1
Callaghan, D.2
Walker, D.3
Lue, L.F.4
Liu, Q.Y.5
Couraud, P.O.6
Romero, I.A.7
Weksler, B.8
Stanimirovic, D.B.9
Zhang, W.10
-
55
-
-
0034996659
-
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
-
Wautier M.P., Chappey O., Corda S., Stern D.M., Schmidt A.M., Wautier J.L. Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab 2001, 280:E685-E694.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Wautier, M.P.1
Chappey, O.2
Corda, S.3
Stern, D.M.4
Schmidt, A.M.5
Wautier, J.L.6
-
56
-
-
0034981701
-
Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation
-
Xu J., Chen S., Ku G., Ahmed S.H., Xu J., Chen H., Hsu C.Y. Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation. J Cereb Blood Flow Metab 2001, 21:702-710.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 702-710
-
-
Xu, J.1
Chen, S.2
Ku, G.3
Ahmed, S.H.4
Xu, J.5
Chen, H.6
Hsu, C.Y.7
-
57
-
-
0013615899
-
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
-
Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., Schmidt A.M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 1996, 382:685-691.
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
58
-
-
0037112194
-
Amyloid-beta induces smac release via ap-1/bim activation in cerebral endothelial cells
-
Yin K.J., Lee J.M., Chen S.D., Xu J., Hsu C.Y. Amyloid-beta induces smac release via ap-1/bim activation in cerebral endothelial cells. J Neurosci 2002, 22:9764-9770.
-
(2002)
J Neurosci
, vol.22
, pp. 9764-9770
-
-
Yin, K.J.1
Lee, J.M.2
Chen, S.D.3
Xu, J.4
Hsu, C.Y.5
-
59
-
-
70349952431
-
Oligomeric aggregates of amyloid beta peptides:1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor
-
Young K.F., Pasternak S.H., Rylett R.J. Oligomeric aggregates of amyloid beta peptides:1-42 activate ERK/MAPK in SH-SY5Y cells via the alpha7 nicotinic receptor. Neurochem Int 2009, 55:796-801.
-
(2009)
Neurochem Int
, vol.55
, pp. 796-801
-
-
Young, K.F.1
Pasternak, S.H.2
Rylett, R.J.3
-
60
-
-
24644510715
-
Analysis of superoxide anion production in tissue
-
Zanetti M., d'Uscio L.V., Peterson T.E., Katusic Z.S., O'Brien T. Analysis of superoxide anion production in tissue. Methods Mol Med 2005, 108:65-72.
-
(2005)
Methods Mol Med
, vol.108
, pp. 65-72
-
-
Zanetti, M.1
d'Uscio, L.V.2
Peterson, T.E.3
Katusic, Z.S.4
O'Brien, T.5
-
61
-
-
67650888887
-
NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2
-
Zhu D., Hu C., Sheng W., Tan K.S., Haidekker M.A., Sun A.Y., Sun G.Y., Lee J.C.M. NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2. Biochem J 2009, 421:201-210.
-
(2009)
Biochem J
, vol.421
, pp. 201-210
-
-
Zhu, D.1
Hu, C.2
Sheng, W.3
Tan, K.S.4
Haidekker, M.A.5
Sun, A.Y.6
Sun, G.Y.7
Lee, J.C.M.8
-
62
-
-
33751079341
-
Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction
-
Zhu D., Lai Y., Shelat P.B., Hu C., Sun G.Y., Lee J.C. Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction. J Neurosci 2006, 26:11111-11119.
-
(2006)
J Neurosci
, vol.26
, pp. 11111-11119
-
-
Zhu, D.1
Lai, Y.2
Shelat, P.B.3
Hu, C.4
Sun, G.Y.5
Lee, J.C.6
-
63
-
-
46749099351
-
New therapeutic targets in the neurovascular pathway in Alzheimer's disease
-
Zlokovic B.V. New therapeutic targets in the neurovascular pathway in Alzheimer's disease. Neurotherapeutics 2008, 5:409-414.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 409-414
-
-
Zlokovic, B.V.1
|