Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction

Molecular Vision

Volumn 17, Issue , 2011, Pages 2665-2671

  Yi, Kayoung ^a   Chung, Tae Young ^b   Hyon, Joon Young ^c   Koh, Jae Woong ^d   Wee, Won Ryang ^c   Shin, Young Joo ^a  

^a Hallym University College of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

^d Chosun University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; DEXAMETHASONE; GELATINASE B; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 6; MACROPHAGE MIGRATION INHIBITION FACTOR; MYCOPHENOLIC ACID; RAPAMYCIN; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CELL DAMAGE; CELL PROLIFERATION; CHEMICAL BURN; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CORNEA BURN; CORNEA CELL; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANTIOXIDANTS; BURNS, CHEMICAL; CELLS, CULTURED; COCULTURE TECHNIQUES; CORNEA; CORNEAL KERATOCYTES; DEXAMETHASONE; DRUG COMBINATIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-6; INTRAMOLECULAR OXIDOREDUCTASES; LEUKOCYTES, MONONUCLEAR; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MATRIX METALLOPROTEINASE 9; MYCOPHENOLIC ACID; SIROLIMUS; SODIUM HYDROXIDE; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 83055174011     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Freeman BA, Crapo JD. Biology of disease: free radicals and tissue injury. Lab Invest 1982; 47:412-26. [PMID: 6290784]
2. Kubota M, Shimmura S, Kubota S, Miyashita H, Kato N, Noda K, Oawa Y, Usui T, Ishida S, Umezawa K, Kurihara T, Tsubota K. Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model. Invest Ophthalmol Vis Sci 2011; 52:427-33. [PMID: 20847117]
3. Wagoner MD. Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol 1997; 41:275-313. [PMID: 9104767]
4. Nuijts RM. Autologous limbal transplantation in unilateral chemical burns. Doc Ophthalmol 1999; 98:257-66. [PMID: 10945445]
5. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007; 39:44-84. [PMID: 16978905]
6. Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82:47-95. [PMID: 11773609]
7. Khodr B, Khalil Z. Modulation of inflammation by reactive oxygen species: implications for aging and tissue repair. Free Radic Biol Med 2001; 30:1-8. [PMID: 11134890]
8. Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, Siegel RM. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med 2011; 208:519-33. [PMID: 21282379]
9. Zhou Q, Wang Y, Yang L, Wang Y, Chen P, Wang Y, Chen P, Wang Y, Dong X, Xie L. Histone deacetylase inhibitors blocked activation and caused senescence of corneal stromal cells. Mol Vis 2008; 14:2556-65. [PMID: 19122829]
10. Burdon RH, Gill V, Rice-Evans C. Oxidative stress and tumor cell proliferation. Free Radic Res Commun 1990; 11:65-76. [PMID: 1963620]
11. Bourcier T, Borderie V, Forgez P, Lombet A, Rostène W, Laroche L. In vitro effect of dexamethasone on human corneal keratocytes. Invest Ophthalmol Vis Sci 1999; 40:1061-70. [PMID: 10235539]
12. Borderie VM, Lopez M, Lombet A, Carvajal-Gonzalez S, Cywiner C, Laroche L. Cryopreservation and culture of human corneal keratocytes. Invest Ophthalmol Vis Sci 1998; 39:1511-9. [PMID: 9660502]
13. Musselmann K, Kane BP, Hassell JR. Isolation of a putative keratocyte activating factor from the corneal stroma. Exp Eye Res 2003; 77:273-9. [PMID: 12907159]
14. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65:55-63. [PMID: 6606682]
15. Pathak S, Goldofsky E, Vivas EX, Bonagura VR, Vambutas A. IL-1β Is Overexpressed and Aberrantly Regulated in Corticosteroid Nonresponders with Autoimmune Inner Ear Disease. J Immunol 2011; 186:1870-9. [PMID: 21199898]
16. Yang L, Hou Y. Different Characters of Spleen OX-62 Positive Dendritic Cells between Fischer and Lewis Rats. Cell Mol Immunol 2006; 3:145-50. [PMID: 16696902]
17. Burdon RH, Rice-Evans C. Free radicals and the regulation of mammalian cell proliferation. Free Radic Res Commun 1989; 6:345-58. [PMID: 2676744]
18. DiBartolomeis SM, Moné JP. Apoptosis: a four-week laboratory investigation for advanced molecular and cellular biology students. Cell Biol Educ 2003; 2:275-95. [PMID: 14673493]
19. Chakravarti S, Wu F, Vij N, Roberts L, Joyce S. Microarray studies reveal macrophage-like function of stromal keratocytes in the cornea. Invest Ophthalmol Vis Sci 2004; 45:3475-84. [PMID: 15452052]
20. Cho YS, Lee J, Lee TH, Lee EY, Lee KU, Park JY, Moon HB. Alpha-Lipoic acid inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. J Allergy Clin Immunol 2004; 114:429-35. [PMID: 15316528]
21. Zhang WJ, Wei H, Hagen T, Frei B. Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proc Natl Acad Sci USA 2007; 104:4077-82. [PMID: 17360480]
22. Saja K, Babu MS, Karunagaran D, Sudhakaran PR. Antiinflammatory effect of curcumin involves downregulation of MMP-9 in blood mononuclear cells. Int Immunopharmacol 2007; 7:1659-67. [PMID: 17996675]
23. Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell 2000; 103:481-90. [PMID: 11081634]
24. Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2:161-74. [PMID: 11990853]
25. Matsubara M, Zieske JD, Fini ME. Mechanism of basement membrane dissolution preceding corneal ulceration. Invest Ophthalmol Vis Sci 1991; 32:3221-37. [PMID: 1660857]
26. Schindler R, Mancilla J, Endres S, Ghorbani R, Clark SC, Dinarello CA. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 1990; 75:40-7. [PMID: 2294996]
27. Calandra T, Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 2003; 3:791-800. [PMID: 14502271]
28. Gadjeva M, Nagashima J, Zaidi T, Mitchell RA, Pier GB. Inhibition of macrophage migration inhibitory factor ameliorates ocular Pseudomonas aeruginosa-induced keratitis. PLoS Pathog 2010; 6:e1000826. [PMID: 20361053]
29. Flaster H, Bernhagen J, Calandra T, Bucala R. The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol 2007; 21:1267-80. [PMID: 17389748]
30. Calandra T, Bernhagen J, Metz CN, Spiegel LA, Bacher M, Donnelly T, Cerami A, Bucala R. MIF as a glucocorticoidinduced modulator of cytokine production. Nature 1995; 377:68-71. [PMID: 7659164]
31. Yu X, Lin SG, Huang XR, Bacher M, Leng L, Bucala R, Lan HY. Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway. J Interferon Cytokine Res 2007; 27:103-9. [PMID: 17316137]
32. Wahl SM. Transforming growth factor beta (TGF-beta) in inflammation: a cause and a cure. J Clin Immunol 1992; 12:61-74. [PMID: 1313827]
33. Leung JC, Chan LY, Tsang AW, Liu EW, Lam MF, Tang SC, Lai KN. Anti-macrophage migration inhibitory factor reduces transforming growth factor-beta 1 expression in experimental IgA nephropathy. Nephrol Dial Transplant 2004; 19:1976-85. [PMID: 15187193]
34. Chaiyaroj SC, Rutta AS, Muenthaisong K, Watkins P, Na Ubol M, Looareesuwan S. Reduced levels of transforming growth factor-β1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria. Acta Trop 2004; 89:319-27. [PMID: 14744558]
35. Andresen JL, Ehlers N. Chemotaxis of human keratocytes is increased by platelet-derived growth factor-BB, epidermal growth factor, transforming growth factor-alpha, acidic fibroblast growth factor, insulin-like growth factor-I, and transforming growth factor-beta. Curr Eye Res 1998; 17:79-87. [PMID: 9472475]